Publications by authors named "James W Welsh"

100Publications

Role of Mitochondria in Cancer Immune Evasion and Potential Therapeutic Approaches.

Front Immunol 2020 16;11:573326. Epub 2020 Oct 16.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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October 2020

The Effects of Time to Treatment Initiation for Patients With Non-small-cell Lung Cancer in the United States.

Clin Lung Cancer 2021 Jan 18;22(1):e84-e97. Epub 2020 Sep 18.

Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA. Electronic address:

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January 2021

Radiation-induced lymphopenia during chemoradiation therapy for non-small cell lung cancer is linked with age, lung V5, and XRCC1 rs25487 genotypes in lymphocytes.

Radiother Oncol 2020 Sep 9;154:187-193. Epub 2020 Sep 9.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address:

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September 2020

Use of Multi-Site Radiation Therapy for Systemic Disease Control.

Int J Radiat Oncol Biol Phys 2021 Feb 13;109(2):352-364. Epub 2020 Aug 13.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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February 2021

Interaction between lymphopenia, radiotherapy technique, dosimetry, and survival outcomes in lung cancer patients receiving combined immunotherapy and radiotherapy.

Radiother Oncol 2020 Sep 7;150:114-120. Epub 2020 Jun 7.

Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, USA. Electronic address:

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September 2020

Definitive Management of Presumed Synchronous Early Stage Non-Small Cell Lung Cancers: Outcomes and Utility of Stereotactic Ablative Radiation Therapy.

Int J Radiat Oncol Biol Phys 2020 Jun 7;107(2):261-269. Epub 2020 Feb 7.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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June 2020

Absolute Lymphocyte Count Predicts Abscopal Responses and Outcomes in Patients Receiving Combined Immunotherapy and Radiation Therapy: Analysis of 3 Phase 1/2 Trials.

Int J Radiat Oncol Biol Phys 2020 Sep 7;108(1):196-203. Epub 2020 Feb 7.

Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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September 2020

Impact of Corticosteroid Administration on Outcomes Following Stereotactic Ablative Radiotherapy for Non-small-cell Lung Cancer.

Clin Lung Cancer 2019 07 15;20(4):e480-e488. Epub 2019 Mar 15.

Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX. Electronic address:

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July 2019

Glycosylation and Antitumor Immunity.

Int Rev Cell Mol Biol 2019 17;343:111-127. Epub 2018 Jul 17.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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February 2020

Outcomes of re-irradiation for brain recurrence after prophylactic or therapeutic whole-brain irradiation for small cell lung Cancer: a retrospective analysis.

Radiat Oncol 2018 Dec 29;13(1):258. Epub 2018 Dec 29.

Department of Radiation Oncology, Unit 97, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030-4009, USA.

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December 2018

A systematic review of the cost and cost-effectiveness studies of immune checkpoint inhibitors.

J Immunother Cancer 2018 11 23;6(1):128. Epub 2018 Nov 23.

Department of Radiation Oncology, Oregon Health & Science University, Portland, OR, USA.

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November 2018

Altered cancer metabolism in mechanisms of immunotherapy resistance.

Pharmacol Ther 2019 03 12;195:162-171. Epub 2018 Nov 12.

Departments of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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March 2019

Toxicity of radiation and immunotherapy combinations.

Adv Radiat Oncol 2018 Oct-Dec;3(4):506-511. Epub 2018 Oct 23.

Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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October 2018

Twice-daily Thoracic Radiotherapy for Limited-stage Small-cell Lung Cancer Does Not Increase the Incidence of Acute Severe Esophagitis.

Clin Lung Cancer 2018 11 22;19(6):e885-e891. Epub 2018 Aug 22.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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November 2018

Overview of ongoing clinical trials investigating combined radiotherapy and immunotherapy.

Immunotherapy 2018 08;10(10):851-0

Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.

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August 2018

Safety of Combined Immunotherapy and Thoracic Radiation Therapy: Analysis of 3 Single-Institutional Phase I/II Trials.

Int J Radiat Oncol Biol Phys 2018 08 27;101(5):1141-1148. Epub 2018 Apr 27.

Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas. Electronic address:

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August 2018

Hematologic variables associated with brain failure in patients with small-cell lung cancer.

Radiother Oncol 2018 09 12;128(3):505-512. Epub 2018 Jun 12.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address:

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September 2018

Cost Analysis of PET/CT Versus CT as Surveillance for Stage III Non-Small-Cell Lung Cancer After Definitive Radiation Therapy.

Clin Lung Cancer 2018 07 17;19(4):e517-e528. Epub 2018 Mar 17.

Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX. Electronic address:

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July 2018

Combining radiation plus immunotherapy to improve systemic immune response.

J Thorac Dis 2018 Feb;10(Suppl 3):S468-S479

Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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February 2018

Radiation therapy and immunotherapy: what is the optimal timing or sequencing?

Immunotherapy 2018 02;10(4):299-316

From the Departments of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.

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February 2018

Prognostic significance of pretreatment total lymphocyte count and neutrophil-to-lymphocyte ratio in extensive-stage small-cell lung cancer.

Radiother Oncol 2018 Mar 2;126(3):499-505. Epub 2018 Feb 2.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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March 2018

Radiation and Anti-Cancer Vaccines: A Winning Combination.

Vaccines (Basel) 2018 Jan 30;6(1). Epub 2018 Jan 30.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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January 2018

Barriers to Combined-Modality Therapy for Limited-Stage Small Cell Lung Cancer.

JAMA Oncol 2018 08 9;4(8):e174504. Epub 2018 Aug 9.

Division of Radiation of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston.

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August 2018

Incidence of Second Malignancy after Successful Treatment of Limited-Stage Small-Cell Lung Cancer and Its Effects on Survival.

J Thorac Oncol 2017 11 10;12(11):1696-1703. Epub 2017 Aug 10.

Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas. Electronic address:

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November 2017

Optimizing Radiotherapy with Immunotherapeutic Approaches.

Adv Exp Med Biol 2017 ;995:53-71

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Anderson Central (Y2.5316), 1515 Holcombe Blvd., Unit 0097, Houston, TX, 77030, USA.

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September 2017

Stereotactic Ablative Radiation Therapy is Highly Safe and Effective for Elderly Patients With Early-stage Non-Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2017 07 21;98(4):900-907. Epub 2016 Dec 21.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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July 2017

Analysis of Factors Affecting Successful Clinical Trial Enrollment in the Context of Three Prospective, Randomized, Controlled Trials.

Int J Radiat Oncol Biol Phys 2017 03 27;97(4):770-777. Epub 2016 Nov 27.

Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas. Electronic address:

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March 2017

Phase I Trial: SABR and Ipilimumab-Response.

Clin Cancer Res 2017 01;23(1):321

Departments of Radiation Oncology and Investigational Cancer Therapeutics, MD Anderson Cancer Center, Houston, Texas.

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January 2017

Stereotactic ablative radiotherapy for adrenal gland metastases: Factors influencing outcomes, patterns of failure, and dosimetric thresholds for toxicity.

Pract Radiat Oncol 2017 May - Jun;7(3):e195-e203. Epub 2016 Sep 13.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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February 2018

Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors.

Cancer J 2016 Jul-Aug;22(4):257-66

From the *Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Departments of †Experimental Radiation Oncology and ‡Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; and Departments of §Dermatology and ∥Pathology, Yale University School of Medicine, New Haven, CT.

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August 2017

Preclinical Rationale and Clinical Considerations for Radiotherapy Plus Immunotherapy: Going Beyond Local Control.

Cancer J 2016 Mar-Apr;22(2):130-7

From the *Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX; †Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA; and ‡Department of Radiation Oncology, University of Texas MD Anderson Cancer Center; and §Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX.

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January 2017

PDL1 Regulation by p53 via miR-34.

J Natl Cancer Inst 2016 Jan 17;108(1). Epub 2015 Nov 17.

Departments of Experimental Radiation Oncology (MAC, DV, XW, YY), Experimental Therapeutics (CI, GAC), and Radiation Oncology (RK, DRG, SK, JWW), The University of Texas MD Anderson Cancer Center, Houston, TX; Mirna Therapeutics, Inc., Austin, TX (HJP, KK, DM, AGB); Ohio State University, Columbus, OH (LA, DPC, KS); Texas Veterinary Pathology Associates (Houston), Houston, TX (DKG).

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January 2016

Author's view: radiation and immunotherapy as systemic therapy for solid tumors.

Oncoimmunology 2015 Jan 20;4(3):e986402. Epub 2015 Jan 20.

Department of Radiation Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.

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January 2015

Intensity-Modulated Radiotherapy versus 3-Dimensional Conformal Radiotherapy Strategies for Locally Advanced Non-Small-Cell Lung Cancer.

Balkan Med J 2014 Dec 13;31(4):286-94. Epub 2014 Sep 13.

Department of Radiation Oncology, Başkent University Adana Faculty of Medicine, Adana, Turkey.

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December 2014

Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer.

Radiother Oncol 2014 Dec 25;113(3):379-84. Epub 2014 Nov 25.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address:

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December 2014

Galectin-1 and immune suppression during radiotherapy.

Clin Cancer Res 2014 Dec 27;20(24):6230-2. Epub 2014 Oct 27.

Department of Radiation Oncology, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania.

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December 2014

Clinical staging of patients with early esophageal adenocarcinoma: does FDG-PET/CT have a role?

J Thorac Oncol 2014 Aug;9(8):1202-6

*Diagnostic Radiology; †Nuclear Medicine; GI Medical Oncology; §Radiation Oncology Department; ‖Gastroenterology Hepatitis and Nutrition; ¶Surgery; #Thoracic and Cardio Surgery-Research; and **Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.

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August 2014

Stereotactic ablative radiotherapy (SABR) using 70 Gy in 10 fractions for non-small cell lung cancer: exploration of clinical indications.

Radiother Oncol 2014 Aug 6;112(2):256-61. Epub 2014 Aug 6.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States. Electronic address:

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August 2014

Lymphopenia association with gross tumor volume and lung V5 and its effects on non-small cell lung cancer patient outcomes.

Int J Radiat Oncol Biol Phys 2014 Aug 8;89(5):1084-1091. Epub 2014 Jul 8.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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August 2014

Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer.

Mol Ther 2014 Aug 5;22(8):1494-1503. Epub 2014 May 5.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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August 2014

Progress in the management of limited-stage small cell lung cancer.

Cancer 2014 Mar 10;120(6):790-8. Epub 2013 Dec 10.

Department, of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; University of California at Irvine School of Medicine, Irvine, California.

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March 2014

The influence of histopathologic tumor viability on long-term survival and recurrence rates following neoadjuvant therapy for esophageal adenocarcinoma.

Ann Surg 2013 Sep;258(3):500-7

Departments of *Thoracic and Cardiovascular Surgery, †GI Medical Oncology, ‡Diagnostic Radiology, §GI Medicine & Nutrition, ¶Pathology, ‖Radiation Therapy, and **Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.

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September 2013

Cardiac ¹⁸F-fluorodeoxyglucose uptake on positron emission tomography after thoracic stereotactic body radiation therapy.

Radiother Oncol 2013 Oct 7;109(1):82-8. Epub 2013 Sep 7.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States; Texas Tech University Health Sciences Center School of Medicine, Lubbock, United States.

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October 2013

Stereotactic ablative radiotherapy: a potentially curable approach to early stage multiple primary lung cancer.

Cancer 2013 Sep 24;119(18):3402-10. Epub 2013 Jun 24.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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September 2013

Surgery is an essential component of multimodality therapy for patients with locally advanced esophageal adenocarcinoma.

J Gastrointest Surg 2013 Aug 29;17(8):1359-69. Epub 2013 May 29.

Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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August 2013

Aortic dose constraints when reirradiating thoracic tumors.

Radiother Oncol 2013 Mar 28;106(3):327-32. Epub 2013 Feb 28.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.

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March 2013

Modulation of c-Met signaling and cellular sensitivity to radiation: potential implications for therapy.

Cancer 2013 May 19;119(10):1768-75. Epub 2013 Feb 19.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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May 2013

Comparative effectiveness of 5 treatment strategies for early-stage non-small cell lung cancer in the elderly.

Int J Radiat Oncol Biol Phys 2012 Dec 11;84(5):1060-70. Epub 2012 Sep 11.

Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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December 2012

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells.

Radiat Oncol 2009 Dec 22;4:69. Epub 2009 Dec 22.

Departmentr of Radiation Oncology, The University of Texas M, D, Anderson Cancer Center, 1515 Holcombe Blvd,, Houston, TX, USA.

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December 2009