Publications by authors named "James Uney"

61Publications

CREB transcription in the medial prefrontal cortex regulates the formation of long-term associative recognition memory.

Learn Mem 2020 02 16;27(2):45-51. Epub 2020 Jan 16.

School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, United Kingdom.

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February 2020

Exosomes populate the cerebrospinal fluid of preterm infants with post-haemorrhagic hydrocephalus.

Int J Dev Neurosci 2019 Apr 9;73:59-65. Epub 2019 Jan 9.

Regenerative Medicine Laboratory, Bristol Medical School, University of Bristol, UK.

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April 2019

Contrasting roles for DNA methyltransferases and histone deacetylases in single-item and associative recognition memory.

Neuroepigenetics 2017 Mar 6;9:1-9. Epub 2017 Mar 6.

School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK.

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March 2017

Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections.

Nat Neurosci 2017 02 9;20(2):242-250. Epub 2017 Jan 9.

School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.

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February 2017

The increasing diversity of functions attributed to the SAFB family of RNA-/DNA-binding proteins.

Biochem J 2016 12;473(23):4271-4288

Regenerative Medicine Laboratories, School of Clinical Sciences, Cellular and Molecular Medicine, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, U.K.

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December 2016

MiR-132 Is Upregulated by Ischemic Preconditioning of Cultured Hippocampal Neurons and Protects them from Subsequent OGD Toxicity.

J Mol Neurosci 2016 Jul 13;59(3):404-10. Epub 2016 Apr 13.

School of Clinical Sciences & School of Cellular and Molecular Medicine, Regenerative Medicine Laboratories, University Walk, Bristol, BS8 1TD, UK.

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July 2016

iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.

BMC Biol 2015 Dec 22;13:111. Epub 2015 Dec 22.

Regenerative Medicine Laboratories, School of Clinical Sciences, Cellular & Molecular Medicine, Medical Sciences Building, University Walk, University of Bristol, Bristol, BS8 1TD, UK.

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December 2015

Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease.

Mol Ther 2015 Feb 5;23(2):244-54. Epub 2014 Nov 5.

1] School of Clinical Sciences, Medical Sciences Building, University Walk, Bristol, UK [2] Regenerative Medicine Laboratory, Medical Sciences Building, University Walk, Bristol, UK.

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February 2015

miR-186 inhibits muscle cell differentiation through myogenin regulation.

J Biol Chem 2014 Feb 2;289(7):3923-35. Epub 2014 Jan 2.

From the Department of Molecular Genetics, Function, and Therapy, The Cyprus Institute of Neurology and Genetics, 1683, Nicosia, Cyprus and.

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February 2014

Twist reverses muscle cell differentiation through transcriptional down-regulation of myogenin.

Biosci Rep 2013 Dec 3;33(6). Epub 2013 Dec 3.

*Department of Molecular Genetics, Function and Therapy, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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December 2013

Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A.

Hum Mol Genet 2013 Jan 5;22(1):74-83. Epub 2012 Oct 5.

Cancer Epigenetics Laboratory, Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK.

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January 2013

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex.

Eur J Neurosci 2012 Oct 30;36(7):2941-8. Epub 2012 Jul 30.

Henry Wellcome Laboratories for Integrative Neuroscience & Endocrinology & MRC Centre for Synaptic Plasticity, Dorothy Hodgkin Building, University of Bristol, Whitson Street, Bristol BS1 3NY, UK.

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October 2012

MiR-3120 is a mirror microRNA that targets heat shock cognate protein 70 and auxilin messenger RNAs and regulates clathrin vesicle uncoating.

J Biol Chem 2012 Apr 5;287(18):14726-33. Epub 2012 Mar 5.

Henry Wellcome Laboratories for Integrated Neuroscience and Endocrinology, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, United Kingdom.

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April 2012

Down-regulation of myogenin can reverse terminal muscle cell differentiation.

PLoS One 2012 3;7(1):e29896. Epub 2012 Jan 3.

Department of Molecular Genetics, Function and Therapy, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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May 2012

Endogenous TWIST expression and differentiation are opposite during human muscle development.

Muscle Nerve 2011 Dec;44(6):984-6

Department of Molecular Genetics, Function & Therapy, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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December 2011

Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.

PLoS One 2011 10;6(8):e23423. Epub 2011 Aug 10.

School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.

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December 2011

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

BMC Dev Biol 2011 Jun 7;11:34. Epub 2011 Jun 7.

Department of Molecular Genetics, Function & Therapy, The Cyprus Institute of Neurology & Genetics, PO Box 2346, 1683 Nicosia, Cyprus.

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June 2011

Connexin 36 expression regulates neuronal differentiation from neural progenitor cells.

PLoS One 2011 Mar 9;6(3):e14746. Epub 2011 Mar 9.

Henry Wellcome Laboratories for Integrative Neuroscience & Endocrinology, University of Bristol, Bristol, United Kingdom.

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March 2011

Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis.

J Neuropathol Exp Neurol 2010 Nov;69(11):1087-95

MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, United Kingdom.

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November 2010

The application of ribozymes and DNAzymes in muscle and brain.

Molecules 2010 Aug 9;15(8):5460-72. Epub 2010 Aug 9.

Department of Molecular Genetics, Function & Therapy, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.

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August 2010

Identifying neural progenitor cells in the adult brain.

Methods Mol Biol 2009 ;549:217-30

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology (LINE), Clinical Sciences at South Bristol, University of Bristol, Bristol, UK.

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June 2009

Twist-1 regulates the miR-199a/214 cluster during development.

Nucleic Acids Res 2009 Jan 23;37(1):123-8. Epub 2008 Nov 23.

The Henry-Wellcome Laboratories for Integrated Neuroscience and Endocrinology, University of Bristol, Bristol, UK.

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January 2009

Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration.

Neurosci Lett 2008 Dec 17;448(1):71-3. Epub 2008 Oct 17.

MS Stem Cell Group, Burden Neurological Institute, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1LE, UK.

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December 2008

The effect of myotonic dystrophy transcript levels and location on muscle differentiation.

Biochem Biophys Res Commun 2008 Dec 16;377(2):526-531. Epub 2008 Oct 16.

The Cyprus Institute of Neurology & Genetics, P.O. Box 23462, 1683 Nicosia, Cyprus. Electronic address:

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December 2008

Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature.

Arterioscler Thromb Vasc Biol 2008 Aug 22;28(8):1462-8. Epub 2008 May 22.

Microvascular Research Laboratories, Bristol Heart Institute, Department of Physiology, University of Bristol, Southwell Street, Bristol BS2 8EJ, United Kingdom.

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August 2008

Expression of long-term depression underlies visual recognition memory.

Neuron 2008 Apr;58(2):186-94

MRC Centre for Synaptic Plasticity, Department of Anatomy, University of Bristol, Bristol BS8 1TD, UK.

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April 2008

Patterned growth of neuronal cells on modified diamond-like carbon substrates.

Biomaterials 2008 Jun 21;29(17):2573-80. Epub 2008 Mar 21.

Henry Wellcome L.I.N.E., Clinical Sciences South Bristol, University of Bristol, UK.

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June 2008

Enhanced green fluorescent protein-expressing human mesenchymal stem cells retain neural marker expression.

J Neuroimmunol 2008 Jan 3;193(1-2):59-67. Epub 2007 Dec 3.

MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, BS16 1JB, UK.

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January 2008

Twist induces reversal of myotube formation.

Differentiation 2008 Feb 27;76(2):182-92. Epub 2007 Jul 27.

The Cyprus Institute of Neurology & Genetics, P.O. Box 23462, 1683 Nicosia, Cyprus.

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February 2008

SAFB re-distribution marks steps of the apoptotic process.

Exp Cell Res 2007 Nov 6;313(18):3914-23. Epub 2007 Jul 6.

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Bristol University, Dorothy Hodgkin Building, Whitson Street Bristol BS1 3NY, UK.

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November 2007

A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.

Biochem J 2007 Nov;407(3):355-62

Henry Wellcome Laboratories for Integrative Neurosciences and Endocrinology, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK.

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November 2007

MicroRNAs and osmotic regulation.

Proc Natl Acad Sci U S A 2006 Oct 9;103(42):15278-9. Epub 2006 Oct 9.

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, United Kingdom.

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October 2006

Twist is required for establishment of the mouse coronal suture.

J Anat 2005 May;206(5):437-44

Department of Molecular Craniofacial Embryology, Graduate School, Tokyo Medical and Dental University, Japan.

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May 2005

Effects of prolactin on hypothalamic supraoptic neurones: evidence for modulation of STAT5 expression and electrical activity.

Neuro Endocrinol Lett 2005 Apr;26(2):125-30

Department of Anatomy, University of Bristol, Pre-clinical Veterinary School, Southwell St, Bristol, BS2 8EJ, UK.

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April 2005

Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus.

Mol Ther 2005 Jan;11(1):89-95

Oxford BioMedica (UK) Ltd., Medawar Centre, Robert Robinson Avenue, The Oxford Science Park, Oxford OX4 4GA, UK.

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January 2005

Increased utility in the CNS of a powerful neuron-specific tetracycline-regulatable adenoviral system developed using a post-transcriptional enhancer.

J Gene Med 2005 May;7(5):576-83

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology (LINE), Bristol University, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK.

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May 2005

Optimizing regulatable gene expression using adenoviral vectors.

Exp Physiol 2005 Jan 12;90(1):33-7. Epub 2004 Nov 12.

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK.

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January 2005

Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs.

J Neurosci 2004 Jun;24(22):5172-6

Medical Research Council, Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.

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June 2004

Adenoviral expression of CREB protects neurons from apoptotic and excitotoxic stress.

Neuroreport 2004 May;15(7):1171-5

The Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology (LINE), Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK.

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May 2004

cAMP-dependent protein kinase A mediation of vasopressin gene expression in the hypothalamus of the osmotically challenged rat.

Mol Cell Neurosci 2003 Sep;24(1):82-90

The University Research Centre for Neuroendocrinology, University of Bristol, Bristol Royal Infirmary, Marlborough Street, Bristol BS2 8HW, England, UK.

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September 2003

Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons.

Mol Cell Neurosci 2003 Jan;22(1):98-106

University Research Centre for Neuroendocrinology and MRC Centre for Synaptic Plasticity, University of Bristol, Marlborough Street, Bristol BS2 8HW, UK.

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January 2003

DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis.

Biochem Biophys Res Commun 2003 Jan;300(1):178-81

The Cyprus Institute of Neurology and Genetics, P.O. Box 23462, 1683 Nicosia, Cyprus.

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January 2003

Adenoviral-mediated, high-level, cell-specific transgene expression: a SYN1-WPRE cassette mediates increased transgene expression with no loss of neuron specificity.

Mol Ther 2002 May;5(5 Pt 1):509-16

MRC Centre for Synaptic Plasticity and University Research Centre for Neuroendocrinology, University of Bristol, Bristol, BS2 8HW, UK.

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May 2002

Cerebral glucose utilization in transgenic mice overexpressing heat shock protein 70 is altered by dizocilpine.

Eur J Neurosci 2002 Mar;15(6):945-52

Wellcome Surgical Institute and Hugh Fraser Neuroscience Laboratories, University of Glasgow, Glasgow, Scotland, UK.

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March 2002