Publications by authors named "James Thaventhiran"

27Publications

Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells.

Elife 2020 11 2;9. Epub 2020 Nov 2.

Infection, Immunity and Inflammation Programme, University College London Great Ormond Street Institute of Child Health, London, United Kingdom.

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November 2020

Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.

Immunity 2020 Aug 30;53(2):353-370.e8. Epub 2020 Jul 30.

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Northern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK. Electronic address:

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August 2020

Repositioning PARP inhibitors for SARS-CoV-2 infection(COVID-19); a new multi-pronged therapy for acute respiratory distress syndrome?

Br J Pharmacol 2020 08 5;177(16):3635-3645. Epub 2020 Jul 5.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

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August 2020

ADA2 deficiency complicated by EBV-driven lymphoproliferative disease.

Clin Immunol 2020 06 27;215:108443. Epub 2020 Apr 27.

Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, United Kingdom; Department of Immunology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom; Department of Medicine, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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June 2020

Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations.

J Allergy Clin Immunol 2020 Oct 9;146(4):901-911. Epub 2020 Apr 9.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS (Centre for Integrative Biological Signalling Studies), University of Freiburg, Freiburg, Germany; RESIST - Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital and University College London, London, United Kingdom; DZIF (German Center for Infection Research) Satellite Center Freiburg, Freiburg, Germany; Rheumatology and Clinical Immunology, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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October 2020

Predicting the Occurrence of Variants in RAG1 and RAG2.

J Clin Immunol 2019 10 6;39(7):688-701. Epub 2019 Aug 6.

Department of Clinical Immunology and Allergy, St James's University Hospital, Beckett Street, Leeds, UK.

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October 2019

Pathogenic NFKB2 variant in the ankyrin repeat domain (R635X) causes a variable antibody deficiency.

Clin Immunol 2019 06 3;203:23-27. Epub 2019 Apr 3.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Department of Pediatric Immunology, Rheumatology and Infectious diseases, Meibergdreef 9, Amsterdam, The Netherlands; Amsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Meibergdreef 9, Amsterdam, The Netherlands. Electronic address:

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June 2019

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway.

J Allergy Clin Immunol 2018 07 6;142(1):311-314.e6. Epub 2018 Mar 6.

Cancer Research UK Cambridge Institute, Cambridge, United Kingdom; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom. Electronic address:

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July 2018

Transcriptional regulation of effector and memory CD8+ T cell fates.

Curr Opin Immunol 2013 Jun 6;25(3):321-8. Epub 2013 Jun 6.

Centre for Lung Infection, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, United Kingdom.

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June 2013

Therapeutic management of primary immunodeficiency in older patients.

Drugs Aging 2013 Jul;30(7):503-12

Department of Immunology and Molecular Pathology, Royal Free Hospital and University College London, London, UK.

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July 2013