James R Heath

James R Heath

UNVERIFIED PROFILE

Are you James R Heath?   Register this Author

Register author
James R Heath

James R Heath

Publications by authors named "James R Heath"

Are you James R Heath?   Register this Author

100Publications

3460Reads

41Profile Views

Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer.

Cell Stem Cell 2019 Oct 5;25(4):542-557.e9. Epub 2019 Sep 5.

Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2019.08.004DOI Listing
October 2019

Framing technology challenges associated with improving cancer immunotherapies.

Authors:
James R Heath

Lab Chip 2019 Oct;19(20):3366-3367

Institute for Systems Biology, Seattle, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9lc90103eDOI Listing
October 2019

Protein-Catalyzed Capture Agents.

Chem Rev 2019 Sep 6;119(17):9950-9970. Epub 2019 Mar 6.

Institute for Systems Biology , 401 Terry Avenue North , Seattle , Washington 98109-5234 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.chemrev.8b00660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731165PMC
September 2019

Inhibition of heme sequestration of histidine-rich protein 2 using multiple epitope-targeted peptides.

J Pept Sci 2019 Sep 25;25(9):e3203. Epub 2019 Jul 25.

Institute for Systems Biology, 401 Terry Ave North, Seattle, WA, 98109-5263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/psc.3203DOI Listing
September 2019

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.

Cell Rep 2019 Sep;28(10):2728-2738.e7

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Blvd., Pasadena, CA 91125, USA; Institute for Systems Biology, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.07.106DOI Listing
September 2019

MATE-Seq: microfluidic antigen-TCR engagement sequencing.

Lab Chip 2019 Sep;19(18):3011-3021

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Blvd, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9lc00538bDOI Listing
September 2019

Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance.

PLoS Comput Biol 2019 Jun 5;15(6):e1007034. Epub 2019 Jun 5.

Institute for Systems Biology, Seattle, Washington, United State of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1007034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576794PMC
June 2019

T cell antigen discovery via signaling and antigen-presenting bifunctional receptors.

Nat Methods 2019 02 28;16(2):191-198. Epub 2019 Jan 28.

Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41592-018-0304-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755906PMC
February 2019

T cell antigen discovery via trogocytosis.

Nat Methods 2019 02 28;16(2):183-190. Epub 2019 Jan 28.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41592-018-0305-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719556PMC
February 2019

Integrated measurement of intracellular proteins and transcripts in single cells.

Lab Chip 2018 10;18(21):3251-3262

California Institute of Techology, Division of Chemistry and Chemical Engineering, Pasadena, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8lc00639cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752714PMC
October 2018

Allosteric Inhibitor of KRas Identified Using a Barcoded Assay Microchip Platform.

Anal Chem 2018 08 19;90(15):8824-8830. Epub 2018 Jul 19.

The Arthur Amos Noyes Laboratory of Chemical Physics, Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.analchem.8b00706
Publisher Site
http://dx.doi.org/10.1021/acs.analchem.8b00706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734936PMC
August 2018

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

Cell 2018 07;174(3):672-687.e27

Departments of Molecular and Cellular Physiology and Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140336PMC
July 2018

Modulating the Folding Landscape of Superoxide Dismutase 1 with Targeted Molecular Binders.

Angew Chem Int Ed Engl 2018 05 25;57(21):6212-6215. Epub 2018 Apr 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC, 172-27, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201802269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295353PMC
May 2018

Epitope-Targeted Macrocyclic Peptide Ligand with Picomolar Cooperative Binding to Interleukin-17F.

Chemistry 2018 Mar 19;24(15):3760-3767. Epub 2018 Feb 19.

Indi Molecular, Inc., 6162 Bristol Parkway, Culver City, CA, 90230, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201704752DOI Listing
March 2018

High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.

Proc Natl Acad Sci U S A 2017 03 21;114(10):2544-2549. Epub 2017 Feb 21.

Key Laboratory of Systems Biomedicine (Ministry of Education), School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1612229114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347549PMC
March 2017

Microfluidics-based single-cell functional proteomics for fundamental and applied biomedical applications.

Annu Rev Anal Chem (Palo Alto Calif) 2014 2;7:275-95. Epub 2014 Jun 2.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125; email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-anchem-071213-020323DOI Listing
December 2016

A Thermodynamic-Based Interpretation of Protein Expression Heterogeneity in Different Glioblastoma Multiforme Tumors Identifies Tumor-Specific Unbalanced Processes.

J Phys Chem B 2016 07 12;120(26):5990-7. Epub 2016 Apr 12.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine and Department of Chemistry and Biochemistry, UCLA , Los Angeles, California 90095, United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.jpcb.6b01692
Publisher Site
http://dx.doi.org/10.1021/acs.jpcb.6b01692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937832PMC
July 2016

Intercellular signaling through secreted proteins induces free-energy gradient-directed cell movement.

Proc Natl Acad Sci U S A 2016 May 2;113(20):5520-5. Epub 2016 May 2.

NanoSystems Biology Cancer Center, Division of Chemistry, California Institute of Technology, Pasadena, CA 91125;

View Article

Download full-text PDF

Source
http://www.pnas.org/lookup/doi/10.1073/pnas.1602171113
Publisher Site
http://dx.doi.org/10.1073/pnas.1602171113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878481PMC
May 2016

Harry Kroto (1939-2016).

Nature 2016 05;533(7604):470

Rice University, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/533470aDOI Listing
May 2016

Degradation of Akt using protein-catalyzed capture agents.

J Pept Sci 2016 Apr 16;22(4):196-200. Epub 2016 Feb 16.

Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, CA 91125.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/psc.2858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883657PMC
April 2016

Single-cell analysis tools for drug discovery and development.

Nat Rev Drug Discov 2016 Mar 16;15(3):204-16. Epub 2015 Dec 16.

Ludwig Institute for Cancer Research San Diego, Department of Pathology and Moores Cancer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrd.2015.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883669PMC
March 2016

Critical Points in Tumorigenesis: A Carcinogen-Initiated Phase Transition Analyzed via Single-Cell Proteomics.

Small 2016 Mar 18;12(11):1425-31. Epub 2016 Jan 18.

Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, 1200 E. California Blvd, Pasadena, CA, 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/smll.201501178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886749PMC
March 2016

Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells.

J Am Chem Soc 2016 Mar 26;138(9):3085-93. Epub 2016 Feb 26.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b12187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887079PMC
March 2016

Correction to "Modeling Dioxygen Reduction at Multicopper Oxidase Cathodes".

J Am Chem Soc 2015 Dec 10;137(50):15978. Epub 2015 Dec 10.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b11603DOI Listing
December 2015

Nanotechnologies for biomedical science and translational medicine.

Authors:
James R Heath

Proc Natl Acad Sci U S A 2015 Nov;112(47):14436-43

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1515202112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664315PMC
November 2015

Epitope targeting of tertiary protein structure enables target-guided synthesis of a potent in-cell inhibitor of botulinum neurotoxin.

Angew Chem Int Ed Engl 2015 Jun 29;54(24):7114-9. Epub 2015 Apr 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, Pasadena, CA 91125 (USA).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201502451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444873PMC
June 2015

Quantitative assessments of glycolysis from single cells.

Technology (Singap World Sci) 2015 Jun 25;3(4):172-178. Epub 2015 Jun 25.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA; NanoSystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1142/S2339547815200058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728151PMC
June 2015

The influence of water on the optical properties of single-layer molybdenum disulfide.

Adv Mater 2015 May 18;27(17):2734-40. Epub 2015 Mar 18.

Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, CA, 91125, USA.

View Article

Download full-text PDF

Source
http://authors.library.caltech.edu/55965/2/adma201500555-sup
Web Search
http://doi.wiley.com/10.1002/adma.201500555
Publisher Site
http://dx.doi.org/10.1002/adma.201500555DOI Listing
May 2015

Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells.

J Am Chem Soc 2015 Apr 19;137(12):4066-9. Epub 2015 Mar 19.

†Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b00944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883658PMC
April 2015

Modeling dioxygen reduction at multicopper oxidase cathodes.

J Am Chem Soc 2014 Oct 17;136(39):13882-7. Epub 2014 Sep 17.

Beckman Institute, Noyes Laboratory of Chemical Physics, California Institute of Technology , Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/ja5077519
Publisher Site
http://dx.doi.org/10.1021/ja5077519DOI Listing
October 2014

Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function.

J Immunol 2014 Jul 16;193(2):940-9. Epub 2014 Jun 16.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1400093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096688PMC
July 2014

Microchip platforms for multiplex single-cell functional proteomics with applications to immunology and cancer research.

Genome Med 2013 29;5(8):75. Epub 2013 Aug 29.

NanoSystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://www.eng.yale.edu/fanlab/Rong_Fan_Group/Publications_f
Web Search
http://genomemedicine.biomedcentral.com/articles/10.1186/gm4
Publisher Site
http://dx.doi.org/10.1186/gm479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978720PMC
June 2014

Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.

Clin Cancer Res 2014 May 14;20(9):2457-65. Epub 2014 Mar 14.

Authors' Affiliations: Departments of Medicine, Surgery, Pathology and Laboratory Medicine, Microbiology, Immunology and Molecular Genetics, and Molecular and Medical Pharmacology; Jonsson Comprehensive Cancer Center; Department of Ophthalmology, Jules Stein Eye Institute; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research; Howard Hughes Medical Institute, University of California, Los Angeles (UCLA); The Angeles Clinic Research Institute, Los Angeles; Department of Medicine, University of California San Diego (UCSD) Moores Cancer Center, La Jolla; Divisions of Chemistry and Biology, California Institute of Technology, Pasadena, California; Department of Medical and Molecular Genetics, Indiana University, and the Indiana University Viral Production Facility (IU VPF), Indianapolis, Indiana; Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada; Mayo Clinic Scottsdale, Scottsdale, Arizona; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut; and Center for Immunology, Roswell Park Cancer Institute, Buffalo, New York.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-13-3017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070853PMC
May 2014

Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis.

Cell Stem Cell 2014 Apr 20;14(4):445-459. Epub 2014 Feb 20.

Division of Biology, California Institute of Technology, 1200 E. California Blvd, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119790PMC
April 2014

Glioblastoma cellular architectures are predicted through the characterization of two-cell interactions.

Proc Natl Acad Sci U S A 2014 Apr 14;111(17):6521-6. Epub 2014 Apr 14.

NanoSystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1404462111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035957PMC
April 2014

A chemical epitope-targeting strategy for protein capture agents: the serine 474 epitope of the kinase Akt2.

Angew Chem Int Ed Engl 2013 Dec 19;52(52):13975-9. Epub 2013 Nov 19.

Department of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, Pasadena, CA 91125 (USA).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201305882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059071PMC
December 2013

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.

Clin Cancer Res 2013 Oct 12;19(20):5722-32. Epub 2013 Sep 12.

Authors' Affiliations: Laboratory of Molecular Pathology, Ludwig Institute for Cancer Research; Moores Cancer Center; University of California San Diego, La Jolla; Celgene Corporation, San Diego; Department of Neurological Surgery and Brain Tumor Research Center, University of California at San Francisco, San Francisco; California Institute of Technology, Pasadena; Henry Singleton Brain Tumor Program; Jonsson Comprehensive Cancer Center; Department of Neurology, David Geffen UCLA School of Medicine; Department of Molecular and Medical Pharmacology; UCLA Medical Scientist Training Program, University of California, Los Angeles, Los Angeles, California; Celgene Corporation, Summit, New Jersey; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Arthur G. James Cancer Hospital, Columbus, Ohio; Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy; INSERM; Metabolomics Platform, Institut Gustave Roussy, Villejuif; Université Paris Descartes/Sorbonne Paris Cité; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers; and Pôle de Biologie, Hôpital Européen Georges Pompidou, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-0527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815450PMC
October 2013

Wetting: Contact with what?

Authors:
Ke Xu James R Heath

Nat Mater 2013 Oct;12(10):872-3

Department of Chemistry, University of California, Berkeley, California 94720, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmat3763DOI Listing
October 2013

A chemically synthesized capture agent enables the selective, sensitive, and robust electrochemical detection of anthrax protective antigen.

ACS Nano 2013 Oct 8;7(10):9452-60. Epub 2013 Oct 8.

Department of Applied Physics and Materials Science, and ‡Division of Chemistry and Chemical Engineering, California Institute of Technology , 1200 East California Boulevard, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nn404296kDOI Listing
October 2013

Hypoxia induces a phase transition within a kinase signaling network in cancer cells.

Proc Natl Acad Sci U S A 2013 Apr 25;110(15):E1352-60. Epub 2013 Mar 25.

NanoSystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1303060110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625329PMC
April 2013

In situ click chemistry: from small molecule discovery to synthetic antibodies.

Integr Biol (Camb) 2013 Jan;5(1):87-95

Department of Experimental Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Experimental Diagnostic Imaging, Unit 603, P.O. Box 301402, Houston, TX 77230-1402, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2ib20110kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716466PMC
January 2013

Catalysis of dioxygen reduction by Thermus thermophilus strain HB27 laccase on ketjen black electrodes.

J Phys Chem B 2013 Jan 28;117(2):527-34. Epub 2012 Nov 28.

California Institute of Technology, Pasadena, California, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/jp309759g
Publisher Site
http://dx.doi.org/10.1021/jp309759gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548030PMC
January 2013

A microfluidic-based bubble generation platform enables analysis of physical property change in phospholipid surfactant layers by interfacial ozone reaction.

Lab Chip 2012 Dec;12(24):5243-8

Nanosystems Biology Cancer Center, California Institute of Technology, MC 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2lc40940bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681610PMC
December 2012

Quantitating cell-cell interaction functions with applications to glioblastoma multiforme cancer cells.

Nano Lett 2012 Dec 7;12(12):6101-6. Epub 2012 Nov 7.

NanoSystems Biology Cancer Center and Kavli Nanoscience Institute, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl302748qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680341PMC
December 2012

Silicon nanowire charge-trap memory incorporating self-assembled iron oxide quantum dots.

Small 2012 Nov 10;8(22):3417-21. Epub 2012 Sep 10.

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, MC 127-72, Pasadena, CA 91125, USA, FAX: (+1) 626-395-2355; Micron Technology, Inc., 3060 N. First Street, San Jose, CA 95134, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/smll.201200940DOI Listing
November 2012

Visualizing local doping effects of individual water clusters on gold(111)-supported graphene.

Nano Lett 2012 Mar 15;12(3):1459-63. Epub 2012 Feb 15.

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/nl2041673
Publisher Site
http://dx.doi.org/10.1021/nl2041673DOI Listing
March 2012

Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells.

Proc Natl Acad Sci U S A 2012 Jan 27;109(2):419-24. Epub 2011 Dec 27.

Nanosystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1110865109
Publisher Site
http://dx.doi.org/10.1073/pnas.1110865109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258586PMC
January 2012

The microscopic structure of adsorbed water on hydrophobic surfaces under ambient conditions.

Nano Lett 2011 Dec 15;11(12):5581-6. Epub 2011 Nov 15.

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://authors.library.caltech.edu/29026/2/nl2036639_si_001.
Web Search
http://pubs.acs.org/doi/abs/10.1021/nl2036639
Publisher Site
http://dx.doi.org/10.1021/nl2036639DOI Listing
December 2011

Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.

J Am Chem Soc 2011 Nov 24;133(45):18280-8. Epub 2011 Oct 24.

Nanosystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, MC-127-72, California Institute of Technology, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja2064389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651860PMC
November 2011

A robotics platform for automated batch fabrication of high density, microfluidics-based DNA microarrays, with applications to single cell, multiplex assays of secreted proteins.

Rev Sci Instrum 2011 Sep;82(9):094301

NanoSystems Biology Cancer Center and Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, 1200 East California Boulevard, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1063/1.3636077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189969PMC
September 2011

High-density, multiplexed patterning of cells at single-cell resolution for tissue engineering and other applications.

Angew Chem Int Ed Engl 2011 Aug 29;50(32):7378-80. Epub 2011 Jun 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201102249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651859PMC
August 2011

Protein signaling networks from single cell fluctuations and information theory profiling.

Biophys J 2011 May;100(10):2378-86

Nanosystems Biology Cancer Center and Kavli Nanoscience Institute, California Institute of Technology, Pasadena, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpj.2011.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093549PMC
May 2011

Atomic force microscopy characterization of room-temperature adlayers of small organic molecules through graphene templating.

J Am Chem Soc 2011 Mar 4;133(8):2334-7. Epub 2011 Feb 4.

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja108554pDOI Listing
March 2011

Batch fabrication of high-performance planar patch-clamp devices in quartz.

Adv Mater 2010 Nov;22(41):4622-7

Broad Fellows Program, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adma.201001793DOI Listing
November 2010

Ultradense, deep subwavelength nanowire array photovoltaics as engineered optical thin films.

Nano Lett 2010 Nov;10(11):4429-34

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/nl102199b
Publisher Site
http://dx.doi.org/10.1021/nl102199bDOI Listing
November 2010

Reduction of thermal conductivity in phononic nanomesh structures.

Nat Nanotechnol 2010 Oct 25;5(10):718-21. Epub 2010 Jul 25.

Division of Chemistry and Chemical Engineering, MC 127-72 1200 East California Boulevard, California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nnano.2010.149DOI Listing
October 2010

Chemistries for patterning robust DNA microbarcodes enable multiplex assays of cytoplasm proteins from single cancer cells.

Chemphyschem 2010 Oct;11(14):3063-9

Division of Chemistry and Chemical Engineering, Nanosystems Biology Cancer Center, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cphc.201000528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681607PMC
October 2010

Achieving the theoretical depairing current limit in superconducting nanomesh films.

Nano Lett 2010 Oct;10(10):4206-10

Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl102584jDOI Listing
October 2010

Graphene visualizes the first water adlayers on mica at ambient conditions.

Science 2010 Sep;329(5996):1188-91

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1192907DOI Listing
September 2010

Scanning tunneling microscopy characterization of the electrical properties of wrinkles in exfoliated graphene monolayers.

Nano Lett 2009 Dec;9(12):4446-51

Division of Chemistry and Chemical Engineering, Kavli Nanoscience Institute, California Institute of Technology, MC 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl902729pDOI Listing
December 2009

Iterative in situ click chemistry creates antibody-like protein-capture agents.

Angew Chem Int Ed Engl 2009 ;48(27):4944-8

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.200900488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716464PMC
September 2009

Self-powered microfluidic chips for multiplexed protein assays from whole blood.

Lab Chip 2009 Jul 16;9(14):2016-20. Epub 2009 Apr 16.

NanoSystems Biology Cancer Center(NSBCC), Kavli Nanoscience Institute, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/b821247cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651861PMC
July 2009

The crossover from two dimensions to one dimension in granular electronic materials.

Nat Nanotechnol 2009 Jun 19;4(6):368-72. Epub 2009 Apr 19.

Kavli Nanoscience Institute and Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nnano.2009.81DOI Listing
June 2009

Fast nonlinear ion transport via field-induced hydrodynamic slip in sub-20-nm hydrophilic nanofluidic transistors.

Nano Lett 2009 Apr;9(4):1315-9

The Kavli Nanoscience Institute and Division of Engineering and Applied Science, Bioengineering, Caltech, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl802931rDOI Listing
April 2009

Free energy barrier for molecular motions in bistable [2]rotaxane molecular electronic devices.

J Phys Chem A 2009 Mar;113(10):2136-43

Materials and Process Simulation Center (MC 139-74), California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jp809213mDOI Listing
March 2009

Nanomedicine targets cancer.

Sci Am 2009 Feb;300(2):44-51

NanoSystems Biology Cancer Center, California Institute of Technology, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700418PMC
http://dx.doi.org/10.1038/scientificamerican0209-44DOI Listing
February 2009

Superlattice nanowire pattern transfer (SNAP).

Authors:
James R Heath

Acc Chem Res 2008 Dec;41(12):1609-17

Caltech Division of Chemistry & Chemical Engineering and the Kavli Nanoscience Institute, MC 127-72, 1200 East California Boulevard, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ar800015yDOI Listing
December 2008

Rapid microwave-assisted CNBr cleavage of bead-bound peptides.

J Comb Chem 2008 Nov-Dec;10(6):807-9. Epub 2008 Sep 24.

Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cc800113dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720530PMC
December 2008

Kinetic and thermodynamic approaches for the efficient formation of mechanical bonds.

Acc Chem Res 2008 Dec;41(12):1750-61

Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/ar800067h
Publisher Site
http://dx.doi.org/10.1021/ar800067hDOI Listing
December 2008

Heterogeneous catalysis through microcontact printing.

Angew Chem Int Ed Engl 2008 ;47(51):9927-32

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.200803480DOI Listing
December 2008

Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood.

Nat Biotechnol 2008 Dec 16;26(12):1373-8. Epub 2008 Nov 16.

NanoSystems Biology Cancer Center, California Institute of Technology, MC 127-72, 1200 E. California Blvd., Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.1507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775523PMC
December 2008

Azidation of silicon(111) surfaces.

J Am Chem Soc 2008 Nov 16;130(45):14910-1. Epub 2008 Oct 16.

Division of Chemistry and Chemical Engineering, Noyes Laboratory, 127-72, Kavli Nanoscience Institute, California Institute of Technology, Pasadena, California 91125

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja804448pDOI Listing
November 2008

Long, highly-ordered high-temperature superconductor nanowire arrays.

Authors:
Ke Xu James R Heath

Nano Lett 2008 Nov 28;8(11):3845-9. Epub 2008 Oct 28.

Division of Chemistry and Chemical Engineering, California Institute of Technology, MC 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl802264xDOI Listing
November 2008

Complementary symmetry nanowire logic circuits: experimental demonstrations and in silico optimizations.

ACS Nano 2008 Sep;2(9):1789-98

Division of Chemistry and Chemical Engineering, California Institute of Technology, M/C 127-72, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nn800025qDOI Listing
September 2008

Peptide-nanowire hybrid materials for selective sensing of small molecules.

J Am Chem Soc 2008 Jul 25;130(29):9583-9. Epub 2008 Jun 25.

Kavli NanoScience Institute and the Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja802506dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716463PMC
July 2008