James O Lindsay

James O Lindsay

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James O Lindsay

James O Lindsay

Publications by authors named "James O Lindsay"

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Ulcerative Colitis: Shifting Sands.

Drugs R D 2019 Jun;19(2):227-234

Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s40268-019-0263-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544716PMC
June 2019

Hematopoietic stem cell therapy for autoimmune diseases - Clinical experience and mechanisms.

J Autoimmun 2018 08 20;92:35-46. Epub 2018 Jun 20.

Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, S10 2JF, UK.

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http://dx.doi.org/10.1016/j.jaut.2018.06.002DOI Listing
August 2018

Autologous haematopoietic stem cell transplantation (aHSCT) for severe resistant autoimmune and inflammatory diseases - a guide for the generalist.

Clin Med (Lond) 2018 08;18(4):329-334

Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.7861/clinmedicine.18-4-329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334059PMC
August 2018

Volatile Organic Compounds in Feces Associate With Response to Dietary Intervention in Patients With Irritable Bowel Syndrome.

Clin Gastroenterol Hepatol 2018 03 7;16(3):385-391.e1. Epub 2017 Oct 7.

Department of Nutritional Sciences, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.09.055DOI Listing
March 2018

Monitoring adolescents and young people with inflammatory bowel disease during transition to adult healthcare.

Frontline Gastroenterol 2018 Jan 10;9(1):37-44. Epub 2017 Jan 10.

Bart's Health NHS Trust, The Royal London Hospital, London, UK.

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http://dx.doi.org/10.1136/flgastro-2016-100747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824770PMC
January 2018

Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans.

Inflamm Bowel Dis 2017 12;24(1):136-148

Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1093/ibd/izx024DOI Listing
December 2017

A Diet Low in FODMAPs Reduces Symptoms in Patients With Irritable Bowel Syndrome and A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial.

Gastroenterology 2017 10 15;153(4):936-947. Epub 2017 Jun 15.

Faculty of Life Sciences and Medicine, Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.06.010DOI Listing
October 2017

Indicators of suboptimal tumor necrosis factor antagonist therapy in inflammatory bowel disease.

Dig Liver Dis 2017 Oct 1;49(10):1086-1091. Epub 2017 Aug 1.

Takeda Development Centre Europe Ltd., London, United Kingdom.

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http://dx.doi.org/10.1016/j.dld.2017.07.010DOI Listing
October 2017

ECCO IBD Curriculum.

J Crohns Colitis 2017 Sep;11(9):1039-1043

Department of Gastroenterology, Hospital Clínic Barcelona, Barcelona, Spain.

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https://academic.oup.com/ecco-jcc/ecco-jcc/article/2959901/E
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http://dx.doi.org/10.1093/ecco-jcc/jjx004DOI Listing
September 2017

Living with Crohn's disease: an exploratory cross-sectional qualitative study into decision-making and expectations in relation to autologous haematopoietic stem cell treatment (the DECIDES study).

BMJ Open 2017 Sep 11;7(9):e015201. Epub 2017 Sep 11.

Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre. Queen's Medical Centre, E Floor, Nottingham University Hospitals and University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1136/bmjopen-2016-015201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595183PMC
September 2017

The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients.

PLoS One 2017 13;12(3):e0173664. Epub 2017 Mar 13.

Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine & Dentistry, London E1 2AT United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173664PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348010PMC
August 2017

The gut microbiota of siblings offers insights into microbial pathogenesis of inflammatory bowel disease.

Gut Microbes 2017 07 23;8(4):359-365. Epub 2017 Jan 23.

e King's College London , Faculty of Life Sciences & Medicine, Diabetes and Nutritional Sciences Division , London , UK.

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http://dx.doi.org/10.1080/19490976.2017.1284733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570433PMC
July 2017

MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8.

Cell Tissue Res 2017 05 11;368(2):325-335. Epub 2017 Feb 11.

Centre for Genomics and Child Health and National Centre for Bowel Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark St, Whitechapel, E1 2AT, London, UK.

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http://dx.doi.org/10.1007/s00441-017-2576-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397660PMC
May 2017

Antigen-Presenting Human γδ T Cells Promote Intestinal CD4 T Cell Expression of IL-22 and Mucosal Release of Calprotectin.

J Immunol 2017 05 22;198(9):3417-3425. Epub 2017 Mar 22.

Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1700003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392732PMC
May 2017

Predicting Outcomes to Optimize Disease Management in Inflammatory Bowel Diseases.

J Crohns Colitis 2016 Dec 9;10(12):1385-1394. Epub 2016 Jun 9.

The Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

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http://dx.doi.org/10.1093/ecco-jcc/jjw116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174730PMC
December 2016

Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours.

Oncoscience 2016 30;3(5-6):173-85. Epub 2016 Jun 30.

Centre for Genomics and Child Health and National Centre for Bowel Research and Surgical Innovation, Barts and The London School of Medicine & Dentistry, London, United Kingdom.

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http://dx.doi.org/10.18632/oncoscience.312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965260PMC
August 2016

Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities.

Gut 2016 06 8;65(6):944-53. Epub 2015 Apr 8.

Faculty of Life Sciences & Medicine, Diabetes and Nutritional Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2014-308896DOI Listing
June 2016

Food-related Quality of Life in Inflammatory Bowel Disease: Development and Validation of a Questionnaire.

J Crohns Colitis 2016 Feb 27;10(2):194-201. Epub 2015 Oct 27.

King's College London, Diabetes and Nutritional Sciences Division, London, UK

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http://dx.doi.org/10.1093/ecco-jcc/jjv192DOI Listing
February 2016

Inflammatory bowel disease in young patients: challenges faced by black and minority ethnic communities in the UK.

Health Soc Care Community 2015 Nov 9;23(6):665-72. Epub 2015 Feb 9.

Department of Gastroenterology, St George's Hospital, London, UK.

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http://dx.doi.org/10.1111/hsc.12188DOI Listing
November 2015

Dietary intake of inulin-type fructans in active and inactive Crohn's disease and healthy controls: a case-control study.

J Crohns Colitis 2015 Nov 27;9(11):1024-31. Epub 2015 Jul 27.

King's College London, Faculty of Life Sciences and Medicine, Diabetes and Nutritional Sciences Division, London , UK

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http://dx.doi.org/10.1093/ecco-jcc/jjv136DOI Listing
November 2015

Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype.

Inflamm Bowel Dis 2015 Aug;21(8):1926-34

*Centre for Digestive Diseases, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom; †Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom; ‡Department of Surgery and Cancer, Imperial College London, London, United Kingdom; §Centre for Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom; ‖Department of Cellular Pathology, The Royal London Hospital, London, United Kingdom; ¶Department of Internal Medicine, S. Matteo Hospital, University of Pavia, Pavia, Italy; and **Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000443DOI Listing
August 2015

Intestinal fibrosis in Crohn's disease: role of microRNAs as fibrogenic modulators, serum biomarkers, and therapeutic targets.

Inflamm Bowel Dis 2015 May;21(5):1141-50

*Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom; and †Department of Cellular Pathology, The Royal London Hospital, London, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000298DOI Listing
May 2015

Guidance: The practical management of the gastrointestinal symptoms of pelvic radiation disease.

Frontline Gastroenterol 2015 Jan 17;6(1):53-72. Epub 2014 Jun 17.

Digestive Diseases Clinical Academic Unit , Barts and The London School of Medicine and Dentistry, Queen Mary University of London , London , UK.

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http://dx.doi.org/10.1136/flgastro-2014-100468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283714PMC
January 2015

Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings.

Gut 2014 Oct 7;63(10):1578-86. Epub 2014 Jan 7.

Centre for Digestive Diseases, Blizard Institute, Queen Mary University of London, London, UK Gastroenterology Division, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2013-306226DOI Listing
October 2014

In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts.

Clin Sci (Lond) 2014 Sep;127(5):341-50

*Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K.

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http://dx.doi.org/10.1042/CS20140048DOI Listing
September 2014

Smoking in inflammatory bowel disease: impact on disease course and insights into the aetiology of its effect.

J Crohns Colitis 2014 Aug 11;8(8):717-25. Epub 2014 Mar 11.

Digestive Disease Clinical Academic Unit, Barts Health NHS Trust, London, United Kingdom; Centre for Digestive Diseases, Blizard Institute of Cell and Molecular Science, Queen Mary University of London, London, United Kingdom. Electronic address:

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http://ecco-jcc.oxfordjournals.org/content/eccojc/8/8/717.fu
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http://ecco-jcc.oxfordjournals.org/cgi/doi/10.1016/j.crohns.
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http://dx.doi.org/10.1016/j.crohns.2014.02.002DOI Listing
August 2014

Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease.

Gastroenterology 2014 May 4;146(5):1278-88.e1-2. Epub 2014 Feb 4.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, England. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.01.057DOI Listing
May 2014

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

Inflamm Bowel Dis 2014 Mar;20(3):514-24

*Centre for Digestive Diseases, Blizard Institute, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; †National Centre for Bowel Research and Surgical Innovation, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; ‡Flow Cytometry Core Facility, Blizard Institute, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; §Department of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany; ‖Department of Cellular Pathology, Royal London Hospital, London, United Kingdom; ¶Division of Pulmonary and Critical Care Medicine, Genome and Biomedical Sciences Facility, University of California at Davis, Davis, California; and **Department of Pathology, Genentech, Inc., South San Francisco, California.

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http://pdfs.journals.lww.com/ibdjournal/2014/03000/DUOX2_and
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.MIB.0000442012.45038.0eDOI Listing
March 2014

Oral tacrolimus as maintenance therapy for refractory ulcerative colitis--an analysis of outcomes in two London tertiary centres.

J Crohns Colitis 2013 Dec 25;7(11):e516-21. Epub 2013 Apr 25.

IBD Unit, St Mark's Hospital, Harrow, London HA1 3UJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.crohns.2013.03.008DOI Listing
December 2013

Algorithm-based management of patients with gastrointestinal symptoms in patients after pelvic radiation treatment (ORBIT): a randomised controlled trial.

Lancet 2013 Dec 23;382(9910):2084-92. Epub 2013 Sep 23.

Digestive Diseases Clinical Academic Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://dx.doi.org/10.1016/S0140-6736(13)61648-7DOI Listing
December 2013

Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells.

J Immunol 2013 Sep 31;191(5):2752-63. Epub 2013 Jul 31.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1202959DOI Listing
September 2013

Prevalence and management of anemia in children, adolescents, and adults with inflammatory bowel disease.

Inflamm Bowel Dis 2012 Mar 20;18(3):513-9. Epub 2011 May 20.

Digestive Diseases Clinical Academic Unit, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary's University, London, UK.

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http://dx.doi.org/10.1002/ibd.21740DOI Listing
March 2012

Family studies in Crohn's disease: new horizons in understanding disease pathogenesis, risk and prevention.

Gut 2012 Feb 11;61(2):311-8. Epub 2011 May 11.

King's College London, School of Medicine, Diabetes and Nutritional Sciences Division, London, UK.

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http://dx.doi.org/10.1136/gut.2011.238568DOI Listing
February 2012

Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE.

J Immunol 2010 Oct 10;185(7):4118-27. Epub 2010 Sep 10.

Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Whitechapel, London.

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http://dx.doi.org/10.4049/jimmunol.1000500DOI Listing
October 2010

Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials.

Proc Nutr Soc 2007 Aug;66(3):307-15

Nutritional Sciences Division, King's College London, London SE1 9NH, UK.

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http://www.journals.cambridge.org/abstract_S0029665107005563
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http://dx.doi.org/10.1017/S0029665107005563DOI Listing
August 2007