James Nuttall

James Nuttall

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James Nuttall

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Effect of heat wave on N fixation and N remobilization of lentil (Lens culinaris MEDIK) grown under Free Air CO Enrichment in a Mediterranean-type environment.

Plant Biol (Stuttg) 2019 Sep 18. Epub 2019 Sep 18.

Department of Agriculture, Science and the Environment, School of Health, Medical and Applied Science, CQUniversity Australia, Rockhampton, QLD, Australia.

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http://dx.doi.org/10.1111/plb.13047DOI Listing
September 2019

A ten-year review of ESBL and non-ESBL Escherichia coli bloodstream infections among children at a tertiary referral hospital in South Africa.

PLoS One 2019 24;14(9):e0222675. Epub 2019 Sep 24.

Paediatric Infectious Diseases Unit, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222675PLOS
September 2019

Management of active tuberculosis in adults with HIV.

Lancet HIV 2019 Jul;6(7):e463-e474

Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, South Africa; Division of Clinical Pharmacology, Department of Medicine, South Africa.

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http://dx.doi.org/10.1016/S2352-3018(19)30154-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750245PMC
July 2019

Current antimicrobial management of community-acquired pneumonia in HIV-infected children.

Expert Opin Pharmacother 2019 04 21;20(5):595-608. Epub 2019 Jan 21.

a Department of Paediatrics and Child Health, Faculty of Health Sciences , University of Cape Town and Red Cross War Memorial Children's Hospital , Cape Town , South Africa.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2018.1
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http://dx.doi.org/10.1080/14656566.2018.1561864DOI Listing
April 2019

Bloodstream infections at a tertiary level paediatric hospital in South Africa.

BMC Infect Dis 2017 12 6;17(1):750. Epub 2017 Dec 6.

Paediatric Infectious Diseases Unit, Red Cross War Memorial Children's Hospital and the Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12879-017-2862-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718141PMC
December 2017

Reevaluation of the role of Pex1 and dynamin-related proteins in peroxisome membrane biogenesis.

J Cell Biol 2015 Dec;211(5):1041-56

Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, England, UK

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http://dx.doi.org/10.1083/jcb.201412066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674274PMC
December 2015

Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004-2012.

J Acquir Immune Defic Syndr 2015 Aug;69(5):593-601

*School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; †MMed Paeds and Child Health (UNZA), Centre for Infectious Disease Research in Zambia, Lusaka, Zambia; ‡Tygerberg Academic Hospital and Stellenbosch University, Cape Town, South Africa; §Lighthouse Trust Clinic, Lilongwe, Malawi; ‖Red Cross War Memorial Children's Hospital, Cape Town, South Africa; ¶School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa; #Wits Reproductive Health and HIV Institute (Wits RHI), University of the Witwatersrand, Johannesburg, South Africa; **Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Rahima Moosa Mother and Child Hospital and University of the Witwatersrand, Johannesburg, South Africa; ††Médecins Sans Frontierès, Khayelitsha and School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; ‡‡Gugulethu Community Health Centre and Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa; §§Newlands Clinic, Harare, Zimbabwe; ‖‖Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; ¶¶McCord Hospital, Durban, South Africa; and ##Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAI.0000000000000683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509628PMC
August 2015

Antiretroviral therapy during the neonatal period.

South Afr J HIV Med 2015 4;16(1):361. Epub 2015 May 4.

Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.4102/sajhivmed.v16i1.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843175PMC
May 2015

Steady-state pharmacokinetics of nevirapine extended-release tablets in HIV-1-infected children and adolescents: an open-label, multiple-dose, cross-over study.

Pediatr Infect Dis J 2014 Jul;33(7):e173-9

From the *Department of Pediatrics, University of Padua, Italy; †Botswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana; ‡Department of Pediatric Pneumology and Immunology, Charité-Universitätsmedizin Berlin, Germany; §Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa; ¶Tati River Clinic, Francistown, Botswana; ‖Department of Pediatrics, Goethe University, Frankfurt, Germany; and **Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT.

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http://dx.doi.org/10.1097/INF.0000000000000241DOI Listing
July 2014

Epidemiology of Staphylococcus aureus bacteraemia at a tertiary children's hospital in Cape Town, South Africa.

PLoS One 2013 22;8(10):e78396. Epub 2013 Oct 22.

Paediatric Infectious Diseases Unit, Red Cross War Memorial Children's Hospital and the School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078396PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805599PMC
May 2014

Deficiency of the exportomer components Pex1, Pex6, and Pex15 causes enhanced pexophagy in Saccharomyces cerevisiae.

Autophagy 2014 May 18;10(5):835-45. Epub 2014 Mar 18.

Department of Molecular Biology and Biotechnology; University of Sheffield, Western Bank; Sheffield, UK.

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http://dx.doi.org/10.4161/auto.28259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119063PMC
May 2014

Developments in pediatric infectious diseases: a review of WSPID 2013.

Expert Rev Anti Infect Ther 2014 Apr 3;12(4):419-22. Epub 2014 Mar 3.

Pediatric Infectious Diseases Unit, Red Cross War Memorial Children's Hospital, Western Cape, South Africa.

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http://dx.doi.org/10.1586/14787210.2014.894460DOI Listing
April 2014

Presentation and outcome of tuberculous meningitis among children: experiences from a tertiary children's hospital.

Afr Health Sci 2014 Mar;14(1):143-9

Red Cross War Memorial Children's Hospital and the School of Child and Adolescent Health, University of Cape Town.

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http://dx.doi.org/10.4314/ahs.v14i1.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449047PMC
March 2014

What are the levels of evidence on which we base decisions for surgical management of lower extremity bone tumors?

Clin Orthop Relat Res 2014 Jan 1;472(1):8-15. Epub 2013 Oct 1.

Division of Orthopaedics, Department of Surgery, McMaster University, 293 Wellington Street North, Suite 110, Hamilton, ON, L8L 8E7, Canada.

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http://dx.doi.org/10.1007/s11999-013-3311-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889455PMC
January 2014

Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum.

Biochem J 2012 Nov;447(3):353-61

Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK.

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http://biochemj.org/lookup/doi/10.1042/BJ20120750
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http://dx.doi.org/10.1042/BJ20120750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465988PMC
November 2012

Atg36: the Saccharomyces cerevisiae receptor for pexophagy.

Autophagy 2012 Nov 9;8(11):1680-1. Epub 2012 Aug 9.

Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK.

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http://www.tandfonline.com/doi/abs/10.4161/auto.21485
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http://dx.doi.org/10.4161/auto.21485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494598PMC
November 2012

Systemic amyloidosis complicating multidrug-resistant tuberculosis in childhood.

Pediatr Infect Dis J 2012 Sep;31(9):994-7

Paediatric Infectious Disease Unit, University of Cape Town, Cape Town, South Africa. drdaveleroux@ gmail.com

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http://dx.doi.org/10.1097/INF.0b013e318260519fDOI Listing
September 2012

BCG Vaccination in HIV-Infected Children.

Tuberc Res Treat 2011 10;2011:712736. Epub 2011 Apr 10.

Paediatric Infectious Diseases Unit, Red Cross Children's Hospital and University of Cape Town, Rondebosch 7700, South Africa.

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http://www.hindawi.com/journals/trt/2011/712736/
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http://dx.doi.org/10.1155/2011/712736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335547PMC
August 2012

South African measles outbreak 2009 - 2010 as experienced by a paediatric hospital.

S Afr Med J 2012 Aug 22;102(9):760-4. Epub 2012 Aug 22.

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

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August 2012

Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae.

EMBO J 2012 Jun 29;31(13):2852-68. Epub 2012 May 29.

Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK.

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http://dx.doi.org/10.1038/emboj.2012.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395097PMC
June 2012

It is time to consider third-line options in antiretroviral-experienced paediatric patients?

J Int AIDS Soc 2011 Nov 15;14:55. Epub 2011 Nov 15.

Division of Medical Virology, Stellenbosch University, and National Health Laboratory Service Tygerberg, Parow, Cape Town, South Africa.

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http://dx.doi.org/10.1186/1758-2652-14-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228719PMC
November 2011

Peroxisome biogenesis: recent advances.

Curr Opin Cell Biol 2011 Aug;23(4):421-6

Dept. Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S09550674110007
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http://dx.doi.org/10.1016/j.ceb.2011.05.005DOI Listing
August 2011

Low rates of hepatotoxicity in HIV-infected children on anti-retroviral therapy with and without isoniazid prophylaxis.

J Trop Pediatr 2010 Jun 26;56(3):159-65. Epub 2009 Aug 26.

Paediatric HIV Service, Groote Schuur Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1093/tropej/fmp079DOI Listing
June 2010

Sequencing of antiretroviral therapy in children in low- and middle-income countries.

Curr Opin HIV AIDS 2010 Jan;5(1):54-60

TREAT Asia/amfAR, The Foundation for AIDS Research, Bangkok, Thailand.

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http://dx.doi.org/10.1097/COH.0b013e3283339bd8DOI Listing
January 2010

A dual function for Pex3p in peroxisome formation and inheritance.

J Cell Biol 2009 Nov 9;187(4):463-71. Epub 2009 Nov 9.

Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, England, UK.

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http://dx.doi.org/10.1083/jcb.200906161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779223PMC
November 2009

The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiae.

Yeast 2009 Jun;26(6):339-47

Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK.

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http://doi.wiley.com/10.1002/yea.1670
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http://dx.doi.org/10.1002/yea.1670DOI Listing
June 2009

Effect of rifampicin on efavirenz pharmacokinetics in HIV-infected children with tuberculosis.

J Acquir Immune Defic Syndr 2009 Apr;50(5):439-43

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0b013e31819c33a3DOI Listing
April 2009

Structural basis of the radicicol resistance displayed by a fungal hsp90.

ACS Chem Biol 2009 Apr;4(4):289-97

Section of Structural Biology, The Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London, U.K.

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http://dx.doi.org/10.1021/cb9000316DOI Listing
April 2009

Bacillus Calmette-Guérin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy.

Int J Infect Dis 2008 Nov 16;12(6):e99-105. Epub 2008 Sep 16.

Paediatric Infectious Diseases Unit, Red Cross Children's Hospital, School of Child and Adolescent Health, University of Cape Town, Rondebosch, 7700, Cape Town, South Africa.

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http://linkinghub.elsevier.com/retrieve/pii/S120197120801413
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http://dx.doi.org/10.1016/j.ijid.2008.06.014DOI Listing
November 2008

Fluorescent protein fusions to a human immunodeficiency virus monoclonal antibody reveal its intracellular transport through the plant endomembrane system.

Plant Biotechnol J 2008 Sep 15;6(7):649-62. Epub 2008 May 15.

School of Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford, UK.

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http://dx.doi.org/10.1111/j.1467-7652.2008.00348.xDOI Listing
September 2008

Adherence to antiretroviral therapy in young children in Cape Town, South Africa, measured by medication return and caregiver self-report: a prospective cohort study.

BMC Pediatr 2008 Sep 4;8:34. Epub 2008 Sep 4.

Red Cross War Memorial Children's Hospital and the School of Child and Adolescent Health, University of Cape Town, Cape Town, The Republic of South Africa.

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http://bmcpediatr.biomedcentral.com/articles/10.1186/1471-24
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http://dx.doi.org/10.1186/1471-2431-8-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533648PMC
September 2008

Effect of rifampicin on lopinavir pharmacokinetics in HIV-infected children with tuberculosis.

J Acquir Immune Defic Syndr 2008 Apr;47(5):566-9

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0b013e3181642257DOI Listing
April 2008

High prevalence of subtherapeutic plasma concentrations of efavirenz in children.

J Acquir Immune Defic Syndr 2007 Jun;45(2):133-6

Pharmacokinetic Research Unit, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0b013e31805c9d52DOI Listing
June 2007

In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity.

Eukaryot Cell 2007 Apr 9;6(4):744-52. Epub 2007 Feb 9.

Department of Molecular Biology and Biotechnology, The University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, United Kingdom.

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http://dx.doi.org/10.1128/EC.00009-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865661PMC
April 2007

Antiretroviral therapy for children: challenges and opportunities.

Ann Trop Paediatr 2007 Mar;27(1):1-10

Red Cross Children's Hospital and School of Child & Adolescent Health, University of Cape Town, South Africa.

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http://dx.doi.org/10.1179/146532807X170448DOI Listing
March 2007

Expression, intracellular targeting and purification of HIV Nef variants in tobacco cells.

BMC Biotechnol 2007 Feb 26;7:12. Epub 2007 Feb 26.

ENEA-BIOTEC Sezione Genetica e Genomica Vegetale, C.R. Casaccia, 00060 Rome, Italy.

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http://dx.doi.org/10.1186/1472-6750-7-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808453PMC
February 2007

Antiretroviral treatment for children.

S Afr Med J 2006 Sep;96(9 Pt 2):988-93

Red Cross War Memorial Children's Hospital, Rondebosch, Cape Town, South Africa.

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September 2006

HIV-1 p24-immunoglobulin fusion molecule: a new strategy for plant-based protein production.

Plant Biotechnol J 2006 Mar;4(2):195-207

Department of Cellular and Molecular Medicine, Infectious Diseases, Immunology Unit, St. George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK.

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http://dx.doi.org/10.1111/j.1467-7652.2005.00171.xDOI Listing
March 2006

A functional antibody lacking N-linked glycans is efficiently folded, assembled and secreted by tobacco mesophyll protoplasts.

Plant Biotechnol J 2005 Sep;3(5):497-504

Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK.

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http://doi.wiley.com/10.1111/j.1467-7652.2005.00140.x
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http://dx.doi.org/10.1111/j.1467-7652.2005.00140.xDOI Listing
September 2005

HIV-infected infants born to women who tested HIV-negative during pregnancy.

S Afr Med J 2004 Oct;94(10):794

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October 2004

Initial experience of a public sector antiretroviral treatment programme for HIV-infected children and their infected parents.

S Afr Med J 2004 Aug;94(8):643-6

Department of Paediatrics and Child Health, Red Cross Children's Hospital and University of Cape Town.

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August 2004

Progressive multifocal leukoencephalopathy after initiation of highly active antiretroviral therapy in a child with advanced human immunodeficiency virus infection: a case of immune reconstitution inflammatory syndrome.

Pediatr Infect Dis J 2004 Jul;23(7):683-5

Division of Paediatric Infectious Diseases, School of Child and Adolescent Health, School of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/01.inf.0000130954.41818.07DOI Listing
July 2004

C-terminal extension of phaseolin with a short methionine-rich sequence can inhibit trimerisation and result in high instability.

Plant Mol Biol 2003 Apr;51(6):885-94

Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK.

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http://dx.doi.org/10.1023/a:1023041901029DOI Listing
April 2003

ER-resident chaperone interactions with recombinant antibodies in transgenic plants.

Eur J Biochem 2002 Dec;269(24):6042-51

Department of Biological Sciences, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1046/j.1432-1033.2002.03302.xDOI Listing
December 2002