James M Allan

James M Allan

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James M Allan

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Telomere length is a critical determinant for survival in multiple myeloma.

Br J Haematol 2017 07 24;178(1):94-98. Epub 2017 Mar 24.

Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1111/bjh.14643DOI Listing
July 2017

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Nat Commun 2017 02 6;8:14175. Epub 2017 Feb 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1038/ncomms14175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303820PMC
February 2017

Pharmacogenetic association of MBL2 and CD95 polymorphisms with grade 3 infection following adjuvant therapy for breast cancer with doxorubicin and cyclophosphamide.

Eur J Cancer 2017 01 8;71:15-24. Epub 2016 Dec 8.

Faculty of Pharmacy, Pharmacy and Bank Building (A15), University of Sydney, Science Road, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.10.035DOI Listing
January 2017

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism.

Cell Rep 2016 08 11;16(8):2061-2067. Epub 2016 Aug 11.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK; Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999417PMC
August 2016

Does radiation-induced c-MYC amplification initiate breast oncogenesis?

Mol Cell Oncol 2016 Jan-Feb;3(1):e1010950. Epub 2015 Feb 3.

Northern Institute for Cancer Research; Newcastle University ; Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1080/23723556.2015.1010950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845163PMC
June 2016

Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.

Inflamm Bowel Dis 2016 Jan;22(1):20-7

*Department of Pediatrics and †Center for Research Informatics, The University of Chicago, Chicago, Illinois; ‡Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom; §Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; ¶F. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; **Department of Genetics and Genomic Sciences and ††Zane Cohen Centre for Digestive Diseases, Department of Medicine, Mount Sinai Hospital, The University of Toronto, Toronto, Ontario, Canada; and ‡‡Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1097/MIB.0000000000000610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679526PMC
January 2016

Distally-based osteocutaneous dorsal metatarsal artery flap for hallux reconstruction.

J Plast Reconstr Aesthet Surg 2014 Sep 10;67(9):1291-4. Epub 2014 May 10.

Department of Plastic and Reconstructive Surgery, Royal Prince Alfred Hospital, Missinden Road, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.bjps.2014.04.013DOI Listing
September 2014

Second malignant neoplasms and cardiovascular disease following radiotherapy.

Health Phys 2014 Feb;106(2):229-46

*Rubin Center for Cancer Survivorship and Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY; †Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Dana-Farber Cancer Institute, Boston, MA; ‡Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK; §Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN; and the University of Tennessee Health Science Center, Memphis, TN; **Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA; ††Nuclear Engineering and Engineering Physics Program, Rensselaer Polytechnic Institute, Troy, NY; ‡‡Department of Radiation Oncology, University of California at Davis, Davis, CA; §§Department of Radiology, Emory University, Atlanta, GA; ***Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY; †††Division ofCancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD; ‡‡‡National Council on Radiation Protection and Measurements, Bethesda, MD, and the Department of Medicine, Vanderbilt University, Nashville, TN.

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http://dx.doi.org/10.1097/HP.0000000000000013DOI Listing
February 2014

Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors.

Nat Rev Clin Oncol 2013 May 26;10(5):289-301. Epub 2013 Mar 26.

Department of Radiation Oncology and Rubin Center for Cancer Survivorship, University of Rochester Medical Center, Rochester, NY 14642-0318, USA.

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http://dx.doi.org/10.1038/nrclinonc.2013.41DOI Listing
May 2013

Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication.

Leuk Lymphoma 2013 Mar 28;54(3):447-8. Epub 2012 Sep 28.

Newcastle Cancer Centre, Northern Institute for Cancer Research, Medical School, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.3109/10428194.2012.728289DOI Listing
March 2013

Second malignant neoplasms and cardiovascular disease following radiotherapy.

J Natl Cancer Inst 2012 Mar 6;104(5):357-70. Epub 2012 Feb 6.

Rubin Center for Cancer Survivorship and Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester Medical Center, 265 Crittenden Blvd, CU 420318, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1093/jnci/djr533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295744PMC
March 2012

A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia.

Blood 2012 Jan 14;119(1):196-205. Epub 2011 Nov 14.

Newcastle Cancer Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom.

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http://dx.doi.org/10.1182/blood-2011-04-349803DOI Listing
January 2012

Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk.

Blood 2010 Jun 15;115(22):4472-7. Epub 2010 Mar 15.

Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1182/blood-2009-09-244483DOI Listing
June 2010

Genetic variation in the folate metabolic pathway and risk of childhood leukemia.

Blood 2010 May 25;115(19):3923-9. Epub 2010 Jan 25.

Epidemiology & Genetics Unit, Department of Health Sciences, University of York, York, UK.

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http://dx.doi.org/10.1182/blood-2009-10-249722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869556PMC
May 2010

Non-homologous end-joining gene profiling reveals distinct expression patterns associated with lymphoma and multiple myeloma.

Br J Haematol 2010 Apr 8;149(2):258-62. Epub 2010 Feb 8.

The Children's Foundation Research Center, Le Bonheur Children's Medical Center, TN 38103, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08088.xDOI Listing
April 2010

Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.

J Clin Oncol 2009 Nov 26;27(33):5519-28. Epub 2009 Oct 26.

Oncology & Clinical Research and Pathology & Tumour Biology Sections, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom.

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http://jco.ascopubs.org/content/27/33/5519.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2008.21.6283
Publisher Site
http://dx.doi.org/10.1200/JCO.2008.21.6283DOI Listing
November 2009

Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma.

Cancer Epidemiol 2009 Oct 6;33(3-4):257-60. Epub 2009 Sep 6.

Department of Biology, University of York, York, YO10 5YW, United Kingdom.

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http://dx.doi.org/10.1016/j.canep.2009.08.002DOI Listing
October 2009

Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay.

Environ Mol Mutagen 2008 Dec;49(9):669-75

Department of Biosciences and Nutrition, Karolinska Institute, 14157 Huddinge, Sweden.

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http://dx.doi.org/10.1002/em.20415DOI Listing
December 2008

Genetic susceptibility to radiogenic cancer in humans.

Authors:
James M Allan

Health Phys 2008 Nov;95(5):677-86

Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1097/01.HP.0000326339.06405.eaDOI Listing
November 2008

MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility.

Blood 2008 Aug 21;112(3):741-9. Epub 2008 Apr 21.

Department of Medicine, University of Chicago Cancer Research Center, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1182/blood-2007-11-126508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481552PMC
August 2008

Risk of leukemia among survivors of testicular cancer: a population-based study of 42,722 patients.

Ann Epidemiol 2008 May;18(5):416-21

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.annepidem.2008.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034178PMC
May 2008

The genetics of cancer survivorship.

Authors:
James M Allan

Hematol Oncol Clin North Am 2008 Apr;22(2):257-69, vi-vii

Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Framlington Place, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1016/j.hoc.2008.01.001DOI Listing
April 2008

RAD51 homologous recombination repair gene haplotypes and risk of acute myeloid leukaemia.

Leuk Res 2007 Feb 4;31(2):169-74. Epub 2006 Aug 4.

Division of Laboratory and Regenerative Medicine, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom.

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http://dx.doi.org/10.1016/j.leukres.2006.05.028DOI Listing
February 2007

A common genetic variant in XPD associates with risk of 5q- and 7q-deleted acute myeloid leukemia.

Blood 2007 Feb 5;109(3):1233-6. Epub 2006 Oct 5.

Epidemiology and Genetics Unit, Department of Health Sciences, University of York, UK.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-07-03
Publisher Site
http://dx.doi.org/10.1182/blood-2006-07-037853DOI Listing
February 2007

Molar pregnancy, childhood cancer and genomic imprinting - is there a link?

Hum Fertil (Camb) 2006 Sep;9(3):171-4

Department of Health Sciences, University of York, York, UK.

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http://dx.doi.org/10.1080/14647270600636400DOI Listing
September 2006

Acute myeloid leukemia following Hodgkin lymphoma: a population-based study of 35,511 patients.

J Natl Cancer Inst 2006 Feb;98(3):215-8

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-7238, USA.

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http://dx.doi.org/10.1093/jnci/djj017DOI Listing
February 2006

Mechanisms of therapy-related carcinogenesis.

Nat Rev Cancer 2005 Dec;5(12):943-55

Epidemiology and Genetics Unit, Department of Biology, University of York, Heslington, York, YO10 5YW, UK.

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http://dx.doi.org/10.1038/nrc1749DOI Listing
December 2005

Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes.

Cancer Epidemiol Biomarkers Prev 2005 Dec;14(12):2999-3003

Epidemiology and Genetics Unit, Department of Health Sciences, University of York, Area 3, Seebohm Rowntree Building YO10 5DD, York, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-05-0515DOI Listing
December 2005

Breast cancer risk following radiotherapy for Hodgkin lymphoma: modification by other risk factors.

Blood 2005 Nov 28;106(10):3358-65. Epub 2005 Jul 28.

Division of Cancer Epidemiology and Genetics and Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.

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http://dx.doi.org/10.1182/blood-2005-04-1535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895063PMC
November 2005

Genetic susceptibility to iatrogenic malignancy.

Pharmacogenomics 2005 Sep;6(6):615-28

Department of Biology, Epidemiology and Genetics Unit, University of York, York, UK.

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http://dx.doi.org/10.2217/14622416.6.6.615DOI Listing
September 2005

Genetic variation in XPD predicts treatment outcome and risk of acute myeloid leukemia following chemotherapy.

Blood 2004 Dec 31;104(13):3872-7. Epub 2004 Aug 31.

Epidemiology and Genetics Unit, Department of Biology, University of York, York, United Kingdom, YO10 5YW.

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http://dx.doi.org/10.1182/blood-2004-06-2161DOI Listing
December 2004

Application of DNA pooling to large studies of disease.

Stat Med 2004 Dec;23(24):3841-50

Department of Health Sciences, Epidemiology and Genetics Unit, University of York, UK.

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http://dx.doi.org/10.1002/sim.1996DOI Listing
December 2004

High-throughput association testing on DNA pools to identify genetic variants that confer susceptibility to acute myeloid leukemia.

Cancer Epidemiol Biomarkers Prev 2004 May;13(5):795-800

Leukaemia Research Fund Epidemiology and Genetics Unit, School of Medicine, University of Leeds, United Kingdom.

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May 2004

Causal models of leukaemia and lymphoma.

IARC Sci Publ 2004 (157):373-92

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley 94720-7360, USA.

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April 2004

Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma.

Blood 2003 Oct 5;102(7):2345-50. Epub 2003 Jun 5.

Academic Unit of Hematology and Oncology, University of Leeds, United Kingdom.

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http://dx.doi.org/10.1182/blood-2003-02-0444DOI Listing
October 2003

Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia.

Cancer Res 2003 Aug;63(15):4327-30

Leukaemia Research Fund, Epidemiology and Genetics Unit, School of Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom.

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August 2003

An intron splice acceptor polymorphism in hMSH2 and risk of leukemia after treatment with chemotherapeutic alkylating agents.

Clin Cancer Res 2003 Aug;9(8):3012-20

Leukaemia Research Fund Epidemiology and Genetics Unit, Academic Unit of Epidemiology, School of Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom.

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August 2003