James Leach

A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets.

Authors:

Xiaoting Zhu Margot A Lazow Austin Schafer Allison Bartlett Shiva Senthil Kumar Deepak Kumar Mishra Phillip Dexheimer Mariko DeWire Christine Fuller James L Leach Maryam Fouladi Rachid Drissi

Acta Neuropathol Commun 2021 Jan 11;9(1):14. Epub 2021 Jan 11.

The Ohio State University College of Medicine, Columbus, OH, USA.

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January 2021

High-gamma modulation language mapping with stereo-EEG: A novel analytic approach and diagnostic validation.

Authors:

Brian Ervin Jason Buroker Leonid Rozhkov Timothy Holloway Paul S Horn Craig Scholle Anna W Byars Francesco T Mangano James L Leach Hansel M Greiner Katherine D Holland Ravindra Arya

Clin Neurophysiol 2020 Dec 16;131(12):2851-2860. Epub 2020 Oct 16.

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address:

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December 2020

A phase I/II study of ribociclib following radiation therapy in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG).

J Neurooncol 2020 Sep 9;149(3):511-522. Epub 2020 Oct 9.

Division of Oncology, Department of Pediatrics College of Medicine, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, MLC 7015, Cincinnati, OH, 45209, USA.

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September 2020

The effects of internal jugular vein compression for modulating and preserving white matter following a season of American tackle football: A prospective longitudinal evaluation of differential head impact exposure.

Authors:

Jed A Diekfuss Weihong Yuan Kim D Barber Foss Jonathan A Dudley Christopher A DiCesare Danielle L Reddington Wen Zhong Katharine S Nissen Jessica L Shafer James L Leach Scott Bonnette Kelsey Logan Jeffery N Epstein Joseph Clark Mekibib Altaye Gregory D Myer

J Neurosci Res 2021 Feb 27;99(2):423-445. Epub 2020 Sep 27.

The SPORT Center, Division of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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February 2021

A 2-week-old Infant Presenting with Seizures.

Authors:

Kelsey E Poisson Cameron W Thomas James L Leach

Neoreviews 2020 09;21(9):e631-e635

Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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September 2020

MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: report from the International DIPG Registry.

Neuro Oncol 2020 11;22(11):1647-1657

Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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November 2020

Electrical stimulation sensorimotor mapping with stereo-EEG.

Authors:

Ravindra Arya Brian Ervin Timothy Holloway Jonathan Dudley Paul S Horn Jason Buroker Leonid Rozhkov Craig Scholle Anna W Byars James L Leach Francesco T Mangano Hansel M Greiner Katherine D Holland

Clin Neurophysiol 2020 Aug 18;131(8):1691-1701. Epub 2020 May 18.

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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August 2020

Response assessment in diffuse intrinsic pontine glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.

Authors:

Tabitha M Cooney Kenneth J Cohen Carolina V Guimaraes Girish Dhall James Leach Maura Massimino Alessandra Erbetta Luisa Chiapparini Fatema Malbari Kim Kramer Ian F Pollack Patricia Baxter Suzanne Laughlin Zoltán Patay Tina Young Poussaint Katherine E Warren

Lancet Oncol 2020 06;21(6):e330-e336

Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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June 2020

Aromatic Stacking Facilitated Self-Assembly of Ultrashort Ionic Complementary Peptide Sequence: β-Sheet Nanofibers with Remarkable Gelation and Interfacial Properties.

Authors:

Jacek K Wychowaniec Ronak Patel James Leach Rachel Mathomes Vikesh Chhabria Yogita Patil-Sen Araida Hidalgo-Bastida Robert T Forbes Joseph M Hayes Mohamed A Elsawy

Biomacromolecules 2020 07 29;21(7):2670-2680. Epub 2020 May 29.

School of Materials, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.

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July 2020

Functional MRI in Children: Current Clinical Applications.

Authors:

Julie B Guerin Hansel M Greiner Francesco T Mangano James L Leach

Semin Pediatr Neurol 2020 Apr 22;33:100800. Epub 2020 Jan 22.

Department of Pediatric Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Radiology, Mayo Clinic, Rochester, MN. Electronic address:

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April 2020

Altered Functional and Structural Connectomes in Female High School Soccer Athletes After a Season of Head Impact Exposure and the Effect of a Novel Collar.

Authors:

Jonathan Dudley Weihong Yuan Jed Diekfuss Kim D Barber Foss Christopher A DiCesare Mekibib Altaye Kelsey Logan James L Leach Gregory D Myer

Brain Connect 2020 08 1;10(6):292-301. Epub 2020 Jun 1.

Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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August 2020

Reading in children with drug-resistant epilepsy was related to functional connectivity in cognitive control regions.

Authors:

Dror Kraus Jennifer Vannest Ravindra Arya John S Hutton James L Leach Francesco T Mangano Jeffrey R Tenney Anna W Byars Thomas G DeWitt Tzipi Horowitz-Kraus

Acta Paediatr 2020 10 13;109(10):2105-2111. Epub 2020 Feb 13.

Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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October 2020

Relative Head Impact Exposure and Brain White Matter Alterations After a Single Season of Competitive Football: A Pilot Comparison of Youth Versus High School Football.

Authors:

Kim D Barber Foss Weihong Yuan Jed A Diekfuss James Leach William Meehan Christopher A DiCesare Gary Solomon Daniel K Schneider James MacDonald Jon Dudley Nelson Cortes Ryan Galloway Mark Halstead Gregory Walker Gregory D Myer

Clin J Sport Med 2019 11;29(6):442-450

Division of Sports Medicine, The SPORT Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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November 2019

Electrical stimulation mapping of language with stereo-EEG.

Authors:

Ravindra Arya Brian Ervin Jonathan Dudley Jason Buroker Leonid Rozhkov Craig Scholle Paul S Horn Jennifer Vannest Anna W Byars James L Leach Francesco T Mangano Hansel M Greiner Katherine D Holland Tracy A Glauser

Epilepsy Behav 2019 10 15;99:106395. Epub 2019 Aug 15.

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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October 2019

Alterations in knee sensorimotor brain functional connectivity contributes to ACL injury in male high-school football players: a prospective neuroimaging analysis.

Authors:

Jed A Diekfuss Dustin R Grooms Katharine S Nissen Daniel K Schneider Kim D Barber Foss Staci Thomas Scott Bonnette Jonathan A Dudley Weihong Yuan Danielle L Reddington Jonathan D Ellis James Leach Michael Gordon Craig Lindsey Ken Rushford Carlee Shafer Gregory D Myer

Braz J Phys Ther 2020 Sep - Oct;24(5):415-423. Epub 2019 Jul 17.

The SPORT Center, Division of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Departments of Pediatrics and Orthopaedic Surgery, University of Cincinnati, Cincinnati, OH, USA; The Micheli Center for Sports Injury Prevention, Waltham, MA, USA.

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July 2019