James L Kennedy

James L Kennedy

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Adequate evidence to support improved outcomes in depression by primary care physicians compared to psychiatrists when using combinatorial pharmacogenomics.

J Psychiatr Res 2019 Oct 15;117:151-152. Epub 2018 Nov 15.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Molecular Brain Science Research Department, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.10.016DOI Listing
October 2019

Impulsivity moderates the effects of dopamine D2 and mixed D1-D2 antagonists in individuals with gambling disorder.

J Psychopharmacol 2019 Aug 20;33(8):1015-1029. Epub 2019 Jun 20.

1 Molecular Brain Sciences Research Department, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.

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http://dx.doi.org/10.1177/0269881119855972DOI Listing
August 2019

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Authors:
Hunna J Watson Zeynep Yilmaz Laura M Thornton Christopher Hübel Jonathan R I Coleman Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Sarah E Medland Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Kirstin L Purves Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Jessica H Baker Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Jaakko Kaprio Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Lars Klareskog Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Melissa A Munn-Chernoff Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op 't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James E Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Garret D Stuber Scott Gordon Jakob Grove Anjali K Henders Anders Juréus Katherine M Kirk Janne T Larsen Richard Parker Liselotte Petersen Jennifer Jordan Martin Kennedy Grant W Montgomery Tracey D Wade Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Nicholas G Martin Preben Bo Mortensen Patrick F Sullivan Gerome Breen Cynthia M Bulik

Nat Genet 2019 Aug 15;51(8):1207-1214. Epub 2019 Jul 15.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41588-019-0439-2DOI Listing
August 2019

The complement system in schizophrenia: where are we now and what's next?

Mol Psychiatry 2019 Aug 22. Epub 2019 Aug 22.

Tanenbaum Centre for Pharmacogenetics, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, 250 College Street, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.1038/s41380-019-0479-0DOI Listing
August 2019

Copy number variant syndromes are frequent in schizophrenia: Progressing towards a CNV-schizophrenia model.

Schizophr Res 2019 Jul 10;209:171-178. Epub 2019 May 10.

Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, 250 College Street, Toronto M5T 1R8, Canada; The Fred A. Litwin Family Centre in Genetic Medicine, University Health Network & Mount Sinai Hospital, 60 Murray Street, Toronto M5T 3L9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.04.026DOI Listing
July 2019

BDNF Val66Met polymorphism and clinical response to antipsychotic treatment in schizophrenia and schizoaffective disorder patients: a meta-analysis.

Pharmacogenomics J 2019 Jun 5;19(3):269-276. Epub 2018 Sep 5.

Psychiatric Neurogenetics Section, Campbell Family Research Institute Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41397-018-0041-5DOI Listing
June 2019

Dr Nurnberger and Colleagues Reply.

J Clin Psychiatry 2019 Apr 9;80(3). Epub 2019 Apr 9.

Centre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada.

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https://www.psychiatrist.com/JCP/article/Pages/2019/v80/19lr
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http://dx.doi.org/10.4088/JCP.19lr12741aDOI Listing
April 2019

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Authors:
Eli A Stahl Gerome Breen Andreas J Forstner Andrew McQuillin Stephan Ripke Vassily Trubetskoy Manuel Mattheisen Yunpeng Wang Jonathan R I Coleman Héléna A Gaspar Christiaan A de Leeuw Stacy Steinberg Jennifer M Whitehead Pavlides Maciej Trzaskowski Enda M Byrne Tune H Pers Peter A Holmans Alexander L Richards Liam Abbott Esben Agerbo Huda Akil Diego Albani Ney Alliey-Rodriguez Thomas D Als Adebayo Anjorin Verneri Antilla Swapnil Awasthi Judith A Badner Marie Bækvad-Hansen Jack D Barchas Nicholas Bass Michael Bauer Richard Belliveau Sarah E Bergen Carsten Bøcker Pedersen Erlend Bøen Marco P Boks James Boocock Monika Budde William Bunney Margit Burmeister Jonas Bybjerg-Grauholm William Byerley Miquel Casas Felecia Cerrato Pablo Cervantes Kimberly Chambert Alexander W Charney Danfeng Chen Claire Churchhouse Toni-Kim Clarke William Coryell David W Craig Cristiana Cruceanu David Curtis Piotr M Czerski Anders M Dale Simone de Jong Franziska Degenhardt Jurgen Del-Favero J Raymond DePaulo Srdjan Djurovic Amanda L Dobbyn Ashley Dumont Torbjørn Elvsåshagen Valentina Escott-Price Chun Chieh Fan Sascha B Fischer Matthew Flickinger Tatiana M Foroud Liz Forty Josef Frank Christine Fraser Nelson B Freimer Louise Frisén Katrin Gade Diane Gage Julie Garnham Claudia Giambartolomei Marianne Giørtz Pedersen Jaqueline Goldstein Scott D Gordon Katherine Gordon-Smith Elaine K Green Melissa J Green Tiffany A Greenwood Jakob Grove Weihua Guan José Guzman-Parra Marian L Hamshere Martin Hautzinger Urs Heilbronner Stefan Herms Maria Hipolito Per Hoffmann Dominic Holland Laura Huckins Stéphane Jamain Jessica S Johnson Anders Juréus Radhika Kandaswamy Robert Karlsson James L Kennedy Sarah Kittel-Schneider James A Knowles Manolis Kogevinas Anna C Koller Ralph Kupka Catharina Lavebratt Jacob Lawrence William B Lawson Markus Leber Phil H Lee Shawn E Levy Jun Z Li Chunyu Liu Susanne Lucae Anna Maaser Donald J MacIntyre Pamela B Mahon Wolfgang Maier Lina Martinsson Steve McCarroll Peter McGuffin Melvin G McInnis James D McKay Helena Medeiros Sarah E Medland Fan Meng Lili Milani Grant W Montgomery Derek W Morris Thomas W Mühleisen Niamh Mullins Hoang Nguyen Caroline M Nievergelt Annelie Nordin Adolfsson Evaristus A Nwulia Claire O'Donovan Loes M Olde Loohuis Anil P S Ori Lilijana Oruc Urban Ösby Roy H Perlis Amy Perry Andrea Pfennig James B Potash Shaun M Purcell Eline J Regeer Andreas Reif Céline S Reinbold John P Rice Fabio Rivas Margarita Rivera Panos Roussos Douglas M Ruderfer Euijung Ryu Cristina Sánchez-Mora Alan F Schatzberg William A Scheftner Nicholas J Schork Cynthia Shannon Weickert Tatyana Shehktman Paul D Shilling Engilbert Sigurdsson Claire Slaney Olav B Smeland Janet L Sobell Christine Søholm Hansen Anne T Spijker David St Clair Michael Steffens John S Strauss Fabian Streit Jana Strohmaier Szabolcs Szelinger Robert C Thompson Thorgeir E Thorgeirsson Jens Treutlein Helmut Vedder Weiqing Wang Stanley J Watson Thomas W Weickert Stephanie H Witt Simon Xi Wei Xu Allan H Young Peter Zandi Peng Zhang Sebastian Zöllner Rolf Adolfsson Ingrid Agartz Martin Alda Lena Backlund Bernhard T Baune Frank Bellivier Wade H Berrettini Joanna M Biernacka Douglas H R Blackwood Michael Boehnke Anders D Børglum Aiden Corvin Nicholas Craddock Mark J Daly Udo Dannlowski Tõnu Esko Bruno Etain Mark Frye Janice M Fullerton Elliot S Gershon Michael Gill Fernando Goes Maria Grigoroiu-Serbanescu Joanna Hauser David M Hougaard Christina M Hultman Ian Jones Lisa A Jones René S Kahn George Kirov Mikael Landén Marion Leboyer Cathryn M Lewis Qingqin S Li Jolanta Lissowska Nicholas G Martin Fermin Mayoral Susan L McElroy Andrew M McIntosh Francis J McMahon Ingrid Melle Andres Metspalu Philip B Mitchell Gunnar Morken Ole Mors Preben Bo Mortensen Bertram Müller-Myhsok Richard M Myers Benjamin M Neale Vishwajit Nimgaonkar Merete Nordentoft Markus M Nöthen Michael C O'Donovan Ketil J Oedegaard Michael J Owen Sara A Paciga Carlos Pato Michele T Pato Danielle Posthuma Josep Antoni Ramos-Quiroga Marta Ribasés Marcella Rietschel Guy A Rouleau Martin Schalling Peter R Schofield Thomas G Schulze Alessandro Serretti Jordan W Smoller Hreinn Stefansson Kari Stefansson Eystein Stordal Patrick F Sullivan Gustavo Turecki Arne E Vaaler Eduard Vieta John B Vincent Thomas Werge John I Nurnberger Naomi R Wray Arianna Di Florio Howard J Edenberg Sven Cichon Roel A Ophoff Laura J Scott Ole A Andreassen John Kelsoe Pamela Sklar

Nat Genet 2019 05 1;51(5):793-803. Epub 2019 May 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.nature.com/articles/s41588-019-0397-8
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http://dx.doi.org/10.1038/s41588-019-0397-8DOI Listing
May 2019

The coming-of-age of pharmacogenetic testing in clinical psychiatry.

Psychiatry Clin Neurosci 2019 05;73(5):203

Pharmacogenetic Research Clinic, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1111/pcn.12832DOI Listing
May 2019

Dr Nurnberger and Colleagues Reply.

J Clin Psychiatry 2019 Apr 9;80(3). Epub 2019 Apr 9.

Centre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada.

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https://www.psychiatrist.com/JCP/article/Pages/2019/v80/19lr
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http://dx.doi.org/10.4088/JCP.19lr12741aDOI Listing
April 2019

Peripheral Biomarkers in Schizophrenia: A Meta-Analysis of Microarray Gene Expression Datasets.

Int J Neuropsychopharmacol 2019 03;22(3):186-193

Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1093/ijnp/pyy103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403089PMC
March 2019

The effect of ethnicity and immigration on treatment resistance in schizophrenia.

Compr Psychiatry 2019 Feb 7;89:28-32. Epub 2018 Dec 7.

Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; University of Naples "Federico II", Naples, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0010440X183020
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http://dx.doi.org/10.1016/j.comppsych.2018.12.003DOI Listing
February 2019

Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia.

World J Biol Psychiatry 2019 01 10;20(1):91-95. Epub 2017 Apr 10.

a Neurogenetics Section, Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science , Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto , ON , Canada.

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http://dx.doi.org/10.1080/15622975.2017.1301681DOI Listing
January 2019

Genetic validation study of protein tyrosine phosphatase receptor type D (PTPRD) gene variants and risk for antipsychotic-induced weight gain.

J Neural Transm (Vienna) 2019 Jan 18;126(1):27-33. Epub 2018 Sep 18.

Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, R-132, Toronto, ON, M5T1R8, Canada.

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http://dx.doi.org/10.1007/s00702-018-1921-1DOI Listing
January 2019

Sex differences in schizophrenia: estrogen and mitochondria.

Neuropsychopharmacology 2019 01 7;44(1):216-217. Epub 2018 Oct 7.

Molecular Brain Science, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://www.nature.com/articles/s41386-018-0228-0
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http://dx.doi.org/10.1038/s41386-018-0228-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235927PMC
January 2019

Enrichment of pathogenic variants in genes associated with inborn errors of metabolism in psychiatric populations.

Am J Med Genet B Neuropsychiatr Genet 2019 Jan 16;180(1):46-54. Epub 2018 Dec 16.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ajmg.b.32702
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http://dx.doi.org/10.1002/ajmg.b.32702DOI Listing
January 2019

Association study of Disrupted-In-Schizophrenia-1 gene variants and tardive dyskinesia.

Neurosci Lett 2018 11 15;686:17-22. Epub 2018 Aug 15.

Neurogenetics Section, Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science Department, Campbell Family Mental Health Research Institute, CAMH, Canada; Institute of Medical Science, University of Toronto, Canada; Department of Psychiatry, University of Toronto, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Canada. Electronic address:

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https://www.sciencedirect.com/journal/neuroscience-letters/v
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https://academic.oup.com/ntr/article-abstract/11/4/404/11007
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https://academic.oup.com/schizophreniabulletin/article/21/2/
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https://linkinghub.elsevier.com/retrieve/pii/S03043940183053
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http://dx.doi.org/10.1016/j.neulet.2018.08.007DOI Listing
November 2018

Childhood emotional abuse, physical abuse, and neglect are associated with theory of mind decoding accuracy in young adults with depression.

Psychiatry Res 2018 10 2;268:501-507. Epub 2018 Aug 2.

Department of Psychology, Queen's University, Kingston, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2018.07.045DOI Listing
October 2018

Circadian genes in major depressive disorder.

World J Biol Psychiatry 2018 Sep 26:1-11. Epub 2018 Sep 26.

a Institute of Medical Sciences, University of Toronto , Toronto , Canada.

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http://dx.doi.org/10.1080/15622975.2018.1500028DOI Listing
September 2018

Combinatorial pharmacogenomics and improved patient outcomes in depression: Treatment by primary care physicians or psychiatrists.

J Psychiatr Res 2018 09 21;104:157-162. Epub 2018 Jul 21.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Molecular Brain Science Research Department, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.07.012DOI Listing
September 2018

Pharmacogenetic evaluation of a DISP1 gene variant in antidepressant treatment of obsessive-compulsive disorder.

Hum Psychopharmacol 2018 07 28;33(4):e2659. Epub 2018 Jun 28.

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hup.2659DOI Listing
July 2018

Genetics of tardive dyskinesia: Promising leads and ways forward.

J Neurol Sci 2018 06 5;389:28-34. Epub 2018 Feb 5.

Neurogenetics Section, Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; Department of Psychiatry, University of Toronto, Canada; Institute of Medical Science, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.02.011DOI Listing
June 2018

The Complex Interaction of Mitochondrial Genetics and Mitochondrial Pathways in Psychiatric Disease.

Mol Neuropsychiatry 2018 Jun 30;4(1):52-69. Epub 2018 May 30.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1159/000488031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032034PMC
June 2018

The Complex Interaction of Mitochondrial Genetics and Mitochondrial Pathways in Psychiatric Disease.

Mol Neuropsychiatry 2018 Jun 30;4(1):52-69. Epub 2018 May 30.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1159/000488031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032034PMC
June 2018

New findings in pharmacogenetics of schizophrenia.

Curr Opin Psychiatry 2018 05;31(3):200-212

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health.

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http://dx.doi.org/10.1097/YCO.0000000000000417DOI Listing
May 2018

A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia.

Biol Psychiatry 2018 05 15;83(9):780-789. Epub 2018 Mar 15.

Department of Statistical Sciences, Faculty of Arts and Science, University of Toronto, Toronto, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.biopsych.2018.02.1175DOI Listing
May 2018

Association study of BDNF and DRD3 genes with alcohol use disorder in Schizophrenia.

Neurosci Lett 2018 04 31;671:1-6. Epub 2018 Jan 31.

Neurogenetics Section, Molecular Brain Science, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Canada; Institute of Medical Science, University of Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043940183003
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http://dx.doi.org/10.1016/j.neulet.2018.01.033DOI Listing
April 2018

DNA methylation and clinical response to antidepressant medication in major depressive disorder: A review and recommendations.

Neurosci Lett 2018 03 4;669:14-23. Epub 2017 Jan 4.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043940163101
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http://dx.doi.org/10.1016/j.neulet.2016.12.071DOI Listing
March 2018

Genetic testing for CYP2D6 and CYP2C19 suggests improved outcome for antidepressant and antipsychotic medication.

Psychiatry Res 2018 Mar 9. Epub 2018 Mar 9.

Pharmacogenetic Research Clinic, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781173133
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http://dx.doi.org/10.1016/j.psychres.2018.02.055DOI Listing
March 2018

Binge Eating Disorder (BED) in Relation to Addictive Behaviors and Personality Risk Factors.

Front Psychol 2017 25;8:579. Epub 2017 Apr 25.

Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ONCanada.

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http://dx.doi.org/10.3389/fpsyg.2017.00579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403820PMC
April 2017

Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain.

Neuropsychobiology 2016 23;74(3):169-175. Epub 2017 May 23.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1159/000457903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653224PMC
February 2018

Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children.

Appetite 2018 Jan 14;120:596-601. Epub 2017 Oct 14.

Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada; Sackler Program for Epigenetics & Psychobiology at McGill University, Montreal, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.appet.2017.10.021DOI Listing
January 2018

Genetic testing as a supporting tool in prescribing psychiatric medication: Design and protocol of the IMPACT study.

J Psychiatr Res 2018 01 1;96:265-272. Epub 2018 Jan 1.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; Molecular Brain Science Research Department, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2017.09.002DOI Listing
January 2018

Genetic epistasis regulates amyloid deposition in resilient aging.

Alzheimers Dement 2017 Oct 17;13(10):1107-1116. Epub 2017 Mar 17.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601013PMC
October 2017

Pattern of gene expression in different stages of schizophrenia: Down-regulation of NPTX2 gene revealed by a meta-analysis of microarray datasets.

Eur Neuropsychopharmacol 2017 10 18;27(10):1054-1063. Epub 2017 Jul 18.

Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S0924977X173042
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http://dx.doi.org/10.1016/j.euroneuro.2017.07.002DOI Listing
October 2017

Dynamic interaction between fetal adversity and a genetic score reflecting dopamine function on developmental outcomes at 36 months.

PLoS One 2017 15;12(5):e0177344. Epub 2017 May 15.

Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Douglas Mental Health University Institute, Montreal, Quèbec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177344PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432105PMC
September 2017

A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain.

Schizophr Res 2017 09 8;187:67-73. Epub 2017 Jul 8.

Neurogenetics Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.06.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660917PMC
September 2017

Applying deep neural networks to unstructured text notes in electronic medical records for phenotyping youth depression.

Evid Based Ment Health 2017 08 24;20(3):83-87. Epub 2017 Jul 24.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/eb-2017-102688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566092PMC
August 2017

Cognitive and psychosocial function in retired professional hockey players.

J Neurol Neurosurg Psychiatry 2017 06 10;88(6):512-519. Epub 2017 Apr 10.

Baycrest Health Sciences, Rotman Research Institute, Toronto, Canada.

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http://dx.doi.org/10.1136/jnnp-2016-315260DOI Listing
June 2017

Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults.

Am J Psychiatry 2017 05 10;174(5):468-475. Epub 2017 Jan 10.

From the Institute of Medical Science, University of Toronto, Toronto; the Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto; the Department of Psychiatry, McGill University, Montreal; the Department of Psychiatry and the Department of Pharmacology, University of Toronto, Toronto; the Department of Psychiatry, University of Pittsburgh, Pittsburgh; the Geriatric Research Education and Clinical Center, VA Pittsburgh Health System, Pittsburgh; and the Healthy Mind Lab, Department of Psychiatry, Washington University, St. Louis.

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http://dx.doi.org/10.1176/appi.ajp.2016.16050617DOI Listing
May 2017

Binge Eating Disorder (BED) in Relation to Addictive Behaviors and Personality Risk Factors.

Front Psychol 2017 25;8:579. Epub 2017 Apr 25.

Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ONCanada.

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http://dx.doi.org/10.3389/fpsyg.2017.00579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403820PMC
April 2017

A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in two independent cohorts of preschool children.

J Child Psychol Psychiatry 2017 02 11;58(2):180-188. Epub 2016 Oct 11.

Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1111/jcpp.12646DOI Listing
February 2017

Investigating Cortical Inhibition in First-Degree Relatives and Probands in Schizophrenia.

Sci Rep 2017 02 27;7:43629. Epub 2017 Feb 27.

Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/srep43629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378912PMC
February 2017

Investigating Cortical Inhibition in First-Degree Relatives and Probands in Schizophrenia.

Sci Rep 2017 02 27;7:43629. Epub 2017 Feb 27.

Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/srep43629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378912PMC
February 2017

Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine.

Mol Neuropsychiatry 2017 Feb 12;2(4):185-197. Epub 2016 Oct 12.

Neuroscience Research Department, Campbell Family Research Institute, Toronto, Ont., Canada; Institute of Medical Science, Toronto, Ont., Canada; Department of Psychiatry, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000449224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318922PMC
February 2017

Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine.

Mol Neuropsychiatry 2017 Feb 12;2(4):185-197. Epub 2016 Oct 12.

Neuroscience Research Department, Campbell Family Research Institute, Toronto, Ont., Canada; Institute of Medical Science, Toronto, Ont., Canada; Department of Psychiatry, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000449224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318922PMC
February 2017

Parallel role for the dopamine D1 receptor in gambling and amphetamine reinforcement in healthy volunteers.

J Psychopharmacol 2017 01 27;31(1):31-42. Epub 2016 Sep 27.

Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1177/0269881116665329DOI Listing
January 2017

A review of molecular genetic studies of neurocognitive deficits in schizophrenia.

Neurosci Biobehav Rev 2017 Jan 17;72:50-67. Epub 2016 Nov 17.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry and Institute of Medical Science, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.neubiorev.2016.10.024DOI Listing
January 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

Association study between the neurexin-1 gene and tardive dyskinesia.

Hum Psychopharmacol 2017 01;32(1)

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hup.2568DOI Listing
January 2017

Rapporteur summaries of plenary, symposia, and oral sessions from the XXIIIrd World Congress of Psychiatric Genetics Meeting in Toronto, Canada, 16-20 October 2015.

Psychiatr Genet 2016 12;26(6):229-257

aNeurogenetics Section bCampbell Family Mental Health Research Institute cClinical Genetics Research Program dKrembil Family Epigenetics Laboratory, Centre for Addiction and Mental Health eDepartment of Psychiatry fInstitute of Medical Science gDepartment of Psychology, University of Toronto hFrederick W. Thompson Anxiety Disorders Centre, Department of Psychiatry, Sunnybrook Health Sciences Centre iThe Dalglish Family 22q Clinic jUniversity Health Network kThe Centre for Applied Genomics, Genetics and Genome Biology, The Hospital for Sick Children, Toronto lMolecular Genetics Unit mBiomedical Sciences Division, Department of Biology, University of Ottawa, Ottawa, Ontario, Canada nMax Planck Institute of Psychiatry oInstitute of Psychiatric Phenomics and Genomics, University of Munich, Munich pDepartment of Translational Research in Psychiatry, Institute of Computational Biology, Helmholtz Zentrum München qDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg rCharité Universitätsmedizin Berlin, Berlin, Germany sDepartment of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary tSchool of Social Work uDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan vStanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Woodbury, New York wDepartment of Psychiatry, University of Iowa, Iowa City, Iowa xVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia yDepartment of Chemistry and Biochemistry zDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA †Department of Nuclear Medicine, Academic Medical Centre, Amsterdam, The Netherlands ‡Institute and Department of Psychiatry, University of São Paulo Medical School, São Paulo §Department of Genetics, Instituto de Biociências ¶ADHD Outpatient Clinic, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil ∥Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden #Department of Psychiatry, University of Calabar Teaching Hospital, Calabar, Nigeria **Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland ††Department of Psychiatry, Hakkari State Hospital, Turkey ‡‡Department of Genetics, University of Delhi, South Campus, New Delhi §§Molecular Genetics Lab, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India ¶¶Genetics Unit, IRCCS Centro S. Giovanni di Dio, Fatebenefratelli, Brescia, Italy ∥∥Queensland Brain Institute, University of Queensland, St Lucia, Queensland, Australia ##Clinic for Psychiatry, Clinical Center of Serbia, Belgrade, Serbia ***Molecular Psychiatric Laboratory, Division of Psychiatry, University College London, London, UK †††Department of Clinical Medicine, Aarhus University, Aarhus ‡‡‡Psychosis Research Unit, Aarhus University Hospital, Risskov, Denmark §§§Human Genetics Lab, Department of Genetics ¶¶¶Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa ∥∥∥Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece ###Nagoya University, Nagoya, Japan ****School of Psychology, Shaanxi Normal University, Xi'an, China ††††School of Psychology, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1097/YPG.0000000000000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134913PMC
December 2016

Impact of histamine receptors H1 and H3 polymorphisms on antipsychotic-induced weight gain.

World J Biol Psychiatry 2018 15;19(sup3):S97-S105. Epub 2016 Dec 15.

a Neurogenetics Section, Neuroscience Department , Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto , ON , Canada.

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http://dx.doi.org/10.1080/15622975.2016.1262061DOI Listing
December 2016

The Role of the Catechol-o-Methyltransferase (COMT) GeneVal158Met in Aggressive Behavior, a Review of Genetic Studies.

Curr Neuropharmacol 2015 ;13(6):802-14

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8 Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759319PMC
September 2016

Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response.

Pharmacogenomics 2016 15;17(2):103-9. Epub 2015 Dec 15.

250 College Street, Pharmacogenetic Research Clinic, Centre for Addiction & Mental Health, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.2217/pgs.15.155DOI Listing
September 2016

Admixture analysis of age at onset in first episode bipolar disorder.

J Affect Disord 2016 Sep 27;201:88-94. Epub 2016 Apr 27.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2016.04.006DOI Listing
September 2016

Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases.

Schizophr Bull 2016 09 30;42(5):1176-84. Epub 2016 May 30.

Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Lancaster Medical School and Data Science Institute, Lancaster University, Lancaster, UK;

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https://academic.oup.com/schizophreniabulletin/article-looku
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http://dx.doi.org/10.1093/schbul/sbw059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988748PMC
September 2016

Prefrontal White Matter Structure Mediates the Influence of GAD1 on Working Memory.

Neuropsychopharmacology 2016 08 29;41(9):2224-31. Epub 2016 Jan 29.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946050PMC
August 2016

FKBP5 interacts with maltreatment in children with extreme, pervasive, and persistent aggression.

Psychiatry Res 2016 Aug 7;242:277-280. Epub 2016 Jun 7.

Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Child, Youth, and Family Services, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.psychres.2015.09.052DOI Listing
August 2016

Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes.

Schizophr Bull 2016 07 27;42(4):1027-36. Epub 2015 Dec 27.

Zucker Hillside Hospital, Glen Oaks, NY; Center for Psychiatric Neuroscience, Feinstein Institute, Manhasset, NY.

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http://dx.doi.org/10.1093/schbul/sbv180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903045PMC
July 2016

Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study.

Brain 2016 07 13;139(Pt 7):2050-62. Epub 2016 May 13.

4 Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada 5 Institute of Medical Science, University of Toronto, Toronto, Canada 7 Department of Psychiatry, University of Toronto, Toronto, Canada 8 Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada 11 Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada 12 Lancaster Medical School and Data Science Institute, Lancaster University, Lancaster, UK.

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http://dx.doi.org/10.1093/brain/aww109DOI Listing
July 2016

Increased Nigral SLC6A3 Activity in Schizophrenia Patients: Findings From the Toronto-McLean Cohorts.

Schizophr Bull 2016 May 26;42(3):772-81. Epub 2015 Dec 26.

Laboratory of Psychiatric Neurogenomics, McLean Hospital, Belmont, MA; Department of Psychiatry, Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.1093/schbul/sbv191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838105PMC
May 2016

Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis.

Int J Neuropsychopharmacol 2016 05 29;19(5). Epub 2016 Apr 29.

Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada (Mr Huang, Dr Zai, Ms Lisoway, Dr Maciukiewicz, Mr Felsky, Dr Tiwari, Dr Müller, and Dr Kennedy); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN (Dr Bishop); Department of Psychiatry, Fujita Health University, Toyoake, Aichi, Japan (Dr Ikeda); Departamento de Psiquiatria, Clinica Universidad de Navarra, Pamplona, Spain (Drs Molero and Ortuno); Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy (Dr Porcelli); Department of Psychiatry, Pomeranian Medical University, Szczecin, Poland (Dr Samochowiec); Department of Pharmacology, Institute of Psychiatry and Neurology, Warsaw, Poland (Dr Mierzejewski); Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, China (Dr Gao); Department of Psychiatry, CIBERSAM, University Hospital Marqués de Valdecilla- IDIVAL, School of Medicine, University of Cantabria, Santander, Spain (Dr Pelayo-Terán); Institute of Genomics and Integrative Biology, Delhi, India (Drs Kaur and Kukreti); Feinberg School of Medicine, Northwestern University, Chicago, IL (Dr Meltzer); Department of Psychiatry, Columbia University Medical Center, New York, NY (Dr Lieberman); Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA (Dr Potkin).

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http://dx.doi.org/10.1093/ijnp/pyv132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886669PMC
May 2016

Association of orexin receptor polymorphisms with antipsychotic-induced weight gain.

World J Biol Psychiatry 2016 04 8;17(3):221-9. Epub 2015 Oct 8.

a Pharmacogenetics Research Clinic, Neurogenetics Section , Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto , ON , Canada .

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http://dx.doi.org/10.3109/15622975.2015.1076173DOI Listing
April 2016

Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.

J Cereb Blood Flow Metab 2016 Apr 13;36(4):819-30. Epub 2016 Jan 13.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada Institute of Medical Science, University of Toronto, King's College Circle, Toronto, ON, Canada

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http://dx.doi.org/10.1177/0271678X15626719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821029PMC
April 2016

Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine.

Hum Psychopharmacol 2016 Mar 15;31(2):121-34. Epub 2016 Feb 15.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hup.2519DOI Listing
March 2016

Possible association between the prolactin receptor gene and callous-unemotional traits among aggressive children.

Psychiatr Genet 2016 Feb;26(1):48-51

aNeurogenetics Section bChild Psychiatry Section, Child, Youth, and Family Program, Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/YPG.0000000000000108DOI Listing
February 2016

Candidate gene analysis of pharmacodynamic targets for antipsychotic dosage.

Pharmacogenomics 2016 Feb 18;17(3):199-208. Epub 2016 Jan 18.

Institute of Medical Science, Faculty of Medicine, University of Toronto, 1 King's College Circle, Room 2374, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.2217/pgs.15.171DOI Listing
February 2016

A Behavioral Genetic Model of the Mechanisms Underlying the Link Between Obesity and Symptoms of ADHD.

J Atten Disord 2016 Jan 21. Epub 2016 Jan 21.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/1087054715618793DOI Listing
January 2016

Corrigendum to "Age at onset of schizophrenia: Cannabis, COMT gene, and their interactions" [Volume 151, Issues 1-3, December 2013, Pages 289-290].

Schizophr Res 2015 Dec 14;169(1-3):507. Epub 2015 Nov 14.

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.09.031DOI Listing
December 2015

Genetic variation in IL-1β, IL-2, IL-6, TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder.

Pharmacogenomics 2015 Nov 10;16(17):1919-29. Epub 2015 Nov 10.

Pharmacogenetic Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction & Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada.

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http://dx.doi.org/10.2217/pgs.15.136DOI Listing
November 2015

Physicians' opinions following pharmacogenetic testing for psychotropic medication.

Psychiatry Res 2015 Oct 7;229(3):913-8. Epub 2015 Aug 7.

Pharmacogenetic Research Clinic, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.07.032DOI Listing
October 2015

Effects of Genotype and Sleep on Temperament.

Pediatrics 2015 Oct 14;136(4):e914-21. Epub 2015 Sep 14.

Ludmer Center for Neuroinformatics and Mental Health, and Douglas Mental Health University Institute, McGill University, Montreal Canada;

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http://dx.doi.org/10.1542/peds.2015-0080DOI Listing
October 2015

Physicians' opinions following pharmacogenetic testing for psychotropic medication.

Psychiatry Res 2015 Oct 7;229(3):913-8. Epub 2015 Aug 7.

Pharmacogenetic Research Clinic, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.07.032DOI Listing
October 2015

Childhood emotional and sexual maltreatment moderate the relation of the serotonin transporter gene to stress generation.

J Abnorm Psychol 2015 May 2;124(2):275-87. Epub 2015 Feb 2.

Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto.

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http://dx.doi.org/10.1037/abn0000034DOI Listing
May 2015

Age at onset mixture analysis and systematic comparison in schizophrenia spectrum disorders: Is the onset heterogeneity dependent on heterogeneous diagnosis?

Schizophr Res 2015 May 25;164(1-3):83-91. Epub 2015 Mar 25.

Schizophrenia Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.03.004DOI Listing
May 2015

Meta-analysis and association of brain-derived neurotrophic factor (BDNF) gene with obsessive-compulsive disorder.

Psychiatr Genet 2015 Apr;25(2):95-6

aNeurogenetics Section, Centre for Addiction and Mental Health bDepartment of Psychiatry and Institute of Medical Science, University of Toronto cDepartment of Psychiatry and Program in Genetics and Genome Biology, Hospital for Sick Children dFrederick W. Thompson Anxiety Disorders Centre and Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/YPG.0000000000000077DOI Listing
April 2015

Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes.

JAMA Psychiatry 2015 Mar;72(3):268-75

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada2Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada3Department of Psychiatry, University of Toronto, T.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.2427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836849PMC
March 2015

Association study of GABAA α2 receptor subunit gene variants in antipsychotic-associated weight gain.

J Clin Psychopharmacol 2015 Feb;35(1):7-12

From the *Neurogenetics Section, Centre for Addiction and Mental Health; †Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; ‡Department of Psychiatry and Psychotherapy, Campus Mitte, Charité Universitätsmedizin Berlin, Berlin, Germany; §Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, Lieber Center for Schizophrenia Research, New York Presbyterian Hospital & Columbia University Medical Center, New York, NY; and ║Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1097/JCP.0000000000000261DOI Listing
February 2015

The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain.

World J Biol Psychiatry 2015 Jan;16(1):45-56

Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health & Department of Psychiatry, University of Toronto , Toronto, ON , Canada.

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http://dx.doi.org/10.3109/15622975.2014.984631DOI Listing
January 2015

The maternal adversity, vulnerability and neurodevelopment project: theory and methodology.

Can J Psychiatry 2014 Sep;59(9):497-508

Professor, McGill University, Montreal, Quebec. Associate Director, Douglas Mental Health University Institute, Montreal, Quebec; Adjunct Senior Investigator, Singapore Institute for Clinical Sciences, Singapore, Republic of Singapore.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168812PMC
http://dx.doi.org/10.1177/070674371405900906DOI Listing
September 2014