James J Moon

James J Moon

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James J Moon

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Bioinspired nucleic acid structures for immune modulation.

Biomaterials 2019 Oct 19;217:119287. Epub 2019 Jun 19.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635102PMC
October 2019

Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection.

ACS Nano 2019 Sep 12. Epub 2019 Sep 12.

Department of Pharmaceutical Sciences , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acsnano.9b03660DOI Listing
September 2019

Engineering patient-specific cancer immunotherapies.

Nat Biomed Eng 2019 Aug 12. Epub 2019 Aug 12.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41551-019-0436-xDOI Listing
August 2019

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.

Cell Rep 2019 Aug;28(7):1758-1772.e4

Division of Immunology, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711398PMC
August 2019

Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis.

Nat Mater 2019 Aug 19. Epub 2019 Aug 19.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41563-019-0462-9DOI Listing
August 2019

Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer.

Surgery 2019 Jul 29. Epub 2019 Jul 29.

University of Michigan, Department of Surgery, Ann Arbor, MI; University of Michigan, Department of Pharmacology, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2019.06.010DOI Listing
July 2019

Vaccine nanoparticles displaying recombinant Ebola virus glycoprotein for induction of potent antibody and polyfunctional T cell responses.

Nanomedicine 2019 06 22;18:414-425. Epub 2018 Nov 22.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2018.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531357PMC
June 2019

induces intestinal adaptive immune responses during homeostasis.

Science 2019 06;364(6446):1179-1184

Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.

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http://dx.doi.org/10.1126/science.aaw7479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645389PMC
June 2019

Antimicrobial Microwebs of DNA-Histone Inspired from Neutrophil Extracellular Traps.

Adv Mater 2019 Apr 30;31(14):e1807436. Epub 2019 Jan 30.

Wallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA, 30332, USA.

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http://dx.doi.org/10.1002/adma.201807436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467213PMC
April 2019

Generation of Allergen-Specific Tetramers for a Murine Model of Airway Inflammation.

Methods Mol Biol 2018 ;1799:165-181

Department of Immunology, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7896-0_14DOI Listing
February 2019

Dendritic Cell Membrane Vesicles for Activation and Maintenance of Antigen-Specific T Cells.

Adv Healthc Mater 2019 Feb 22;8(4):e1801091. Epub 2018 Nov 22.

Department of Pharmaceutical Sciences, University of Michigan, Biointerfaces Institute, University of Michigan, 2800 Plymouth Drive, Ann Arbor, MI, 48109, USA.

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http://doi.wiley.com/10.1002/adhm.201801091
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http://dx.doi.org/10.1002/adhm.201801091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386464PMC
February 2019

Revealing the Presence of a Symbolic Sequence Representing Multiple Nucleotides Based on K-Means Clustering of Oligonucleotides.

Molecules 2019 Jan 18;24(2). Epub 2019 Jan 18.

School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Gyeonggi-do, South Korea.

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http://dx.doi.org/10.3390/molecules24020348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359743PMC
January 2019

Bioengineered stem cell membrane functionalized nanocarriers for therapeutic targeting of severe hindlimb ischemia.

Biomaterials 2018 12 9;185:360-370. Epub 2018 Aug 9.

Stem Cell Engineering Laboratory, Department of Biomedical Science, CHA University, Pangyo-Ro 335, Bundang-gu, Seongnam-si, Gyeonggi-do 463-400, South Korea; Stem Cells Integrative Engineering Laboratory, Department of Medical Biotechnology, Dongguk University, 32 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10326, South Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183057
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http://dx.doi.org/10.1016/j.biomaterials.2018.08.018DOI Listing
December 2018

Interrogation of Antigen Display on Individual Vaccine Nanoparticles for Achieving Neutralizing Antibody Responses against Hepatitis C Virus.

Nano Lett 2018 12 21;18(12):7832-7838. Epub 2018 Nov 21.

Department of Pharmaceutical Sciences , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.8b03601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465111PMC
December 2018

PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy.

Biomaterials 2018 11 9;182:157-166. Epub 2018 Aug 9.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183057
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http://dx.doi.org/10.1016/j.biomaterials.2018.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156795PMC
November 2018

Immunomodulating Nanomedicine for Cancer Therapy.

Nano Lett 2018 11 10;18(11):6655-6659. Epub 2018 Sep 10.

Department of Radiation Oncology , The University of Texas Southwestern Medical Center , Dallas , Texas 75390 , United States.

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http://pubs.acs.org/doi/10.1021/acs.nanolett.8b02340
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http://dx.doi.org/10.1021/acs.nanolett.8b02340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238186PMC
November 2018

Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance.

Cell Rep 2018 Aug;24(8):2112-2126

Department of Medicine, Section of Rheumatology, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.07.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142813PMC
August 2018

Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy.

J Control Release 2018 07 25;282:131-139. Epub 2018 Apr 25.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.04.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056764PMC
July 2018

NanoDDS 2017: The 15th International Nanomedicine & Drug Delivery Symposium.

J Control Release 2018 07;282:1-2

Department of Pharmaceutical Sciences, Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.jconrel.2018.06.009DOI Listing
July 2018

Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy.

Biomaterials 2018 05 23;165:56-65. Epub 2018 Feb 23.

Department of Radiology, University of Wisconsin-Madison, WI 53705, United States; Department of Medical Physics, University of Wisconsin-Madison, WI 53705, United States; Department of Materials Science and Engineering, University of Wisconsin-Madison, WI 53706, United States; University of Wisconsin Carbone Cancer Center, Madison, WI 53705, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.02.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880312PMC
May 2018

Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal.

Surgery 2018 May 9. Epub 2018 May 9.

Department of Surgery, University of Michigan, Ann Arbor, MI; Department of Pharmacology, University of Michigan, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2018.01.023DOI Listing
May 2018

Guest Editorial Title: Nanomedicine: past, present, and future.

Adv Drug Deliv Rev 2018 05;130:1-2

Department of Pharmaceutical Sciences, Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.addr.2018.07.018DOI Listing
May 2018

High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia.

Biomaterials 2018 04 19;161:69-80. Epub 2018 Jan 19.

Department of Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea; Center for Nanomedicine, Institute for Basic Science (IBS), Seoul, 03722, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817004PMC
April 2018

Quantitation and Stability of Protein Conjugation on Liposomes for Controlled Density of Surface Epitopes.

Bioconjug Chem 2018 04 19;29(4):1251-1260. Epub 2018 Mar 19.

Department of Pharmaceutical Sciences , 428 Church Street , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00033
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http://dx.doi.org/10.1021/acs.bioconjchem.8b00033DOI Listing
April 2018

Elimination of established tumors with nanodisc-based combination chemoimmunotherapy.

Sci Adv 2018 04 18;4(4):eaao1736. Epub 2018 Apr 18.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1126/sciadv.aao1736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906077PMC
April 2018

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer.

Nat Commun 2018 03 14;9(1):1074. Epub 2018 Mar 14.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1038/s41467-018-03473-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852008PMC
March 2018

Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy.

Nano Lett 2017 12 22;17(12):7387-7393. Epub 2017 Nov 22.

Department of Pharmaceutical Sciences, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.nanolett.7b03218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821496PMC
December 2017

Adjuvant-Loaded Spiky Gold Nanoparticles for Activation of Innate Immune Cells.

Cell Mol Bioeng 2017 Oct 30;10(5):341-355. Epub 2017 Aug 30.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1007/s12195-017-0505-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734115PMC
October 2017

Self-encapsulating Poly(lactic-co-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery.

Mol Pharm 2017 09 22;14(9):3228-3237. Epub 2017 Aug 22.

Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642922PMC
September 2017

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting.

Nanomedicine 2017 Aug 18;13(6):1869-1878. Epub 2017 Apr 18.

Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554706PMC
August 2017

Toward a Single-Dose Vaccination Strategy with Self-Encapsulating PLGA Microspheres.

Adv Healthc Mater 2017 Jun 3;6(12). Epub 2017 Apr 3.

Department of Pharmaceutical Sciences, Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/adhm.201601418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483999PMC
June 2017

Designer vaccine nanodiscs for personalized cancer immunotherapy.

Nat Mater 2017 04 26;16(4):489-496. Epub 2016 Dec 26.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nmat4822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374005PMC
April 2017

Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens.

Int J Nanomedicine 2017 14;12:1251-1264. Epub 2017 Feb 14.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA; Biointerfaces Institute; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.2147/IJN.S125866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317250PMC
April 2017

Vaccine nanoparticles for protection against HIV infection.

Nanomedicine (Lond) 2017 Mar 21;12(6):673-682. Epub 2017 Feb 21.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.2217/nnm-2016-0381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331416PMC
March 2017

Particulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogens.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2017 01 1;9(1). Epub 2016 Apr 1.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045734PMC
http://dx.doi.org/10.1002/wnan.1403DOI Listing
January 2017

High-Density Lipoproteins: Nature's Multifunctional Nanoparticles.

ACS Nano 2016 Mar 25;10(3):3015-41. Epub 2016 Feb 25.

Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , 1150 W. Medical Center Drive, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acsnano.5b07522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918468PMC
March 2016

Synthetic high-density lipoprotein nanoparticles: A novel therapeutic strategy for adrenocortical carcinomas.

Surgery 2016 Jan 12;159(1):284-94. Epub 2015 Nov 12.

Department of Surgery, University of Michigan, Ann Arbor, MI; Department of Pharmacology, University of Michigan, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2015.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709032PMC
January 2016

CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.

Immunity 2015 Nov 10;43(5):896-908. Epub 2015 Nov 10.

Center for Immunology and Inflammatory Diseases, and Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital; and Harvard Medical School, Charlestown, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654997PMC
November 2015

The human T-cell repertoire grows up.

Immunol Cell Biol 2015 Aug 5;93(7):601-2. Epub 2015 May 5.

Center for Immunology and Department of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://dx.doi.org/10.1038/icb.2015.50DOI Listing
August 2015

Nanoparticle Drug Delivery Systems Designed to Improve Cancer Vaccines and Immunotherapy.

Vaccines (Basel) 2015 Aug 27;3(3):662-85. Epub 2015 Aug 27.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.3390/vaccines3030662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586472PMC
August 2015

Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens.

J Control Release 2015 Jun 11;208:121-129. Epub 2015 Apr 11.

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.jconrel.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430437PMC
June 2015

Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8+ T cell responses after nanoparticle vaccination.

J Vis Exp 2015 Apr 29(98):e52771. Epub 2015 Apr 29.

Department of Pharmaceutical Sciences, University of Michigan; Biointerfaces Institute, University of Michigan; Department of Biomedical Engineering, University of Michigan;

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http://dx.doi.org/10.3791/52771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541589PMC
April 2015

Biomaterials for nanoparticle vaccine delivery systems.

Pharm Res 2014 Oct 22;31(10):2563-82. Epub 2014 May 22.

Department of Pharmaceutical Sciences, College of Pharmacy University of Michigan, 2800 Plymouth Road NCRC, Ann Arbor, Michigan, 48109, USA.

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http://link.springer.com/10.1007/s11095-014-1419-y
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http://dx.doi.org/10.1007/s11095-014-1419-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198431PMC
October 2014

A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93.

PLoS One 2014 3;9(1):e83884. Epub 2014 Jan 3.

Infectious Disease Research Institute, Seattle, Washington, United States of America ; Department of Global Health, University of Washington, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083884PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880254PMC
September 2014

CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation.

Immunity 2012 Dec 1;37(6):1091-103. Epub 2012 Nov 1.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.immuni.2012.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525757PMC
December 2012

Peptide:MHC tetramer-based enrichment of epitope-specific T cells.

J Vis Exp 2012 Oct 22(68). Epub 2012 Oct 22.

Center for Immunology and Inflammatory Diseases, and Pulmonary and Critical Care Unit, Massachusetts General Hospital and Harvard Medical School, USA.

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http://www.jove.com/video/4420/peptidemhc-tetramer-based-enr
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http://dx.doi.org/10.3791/4420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490303PMC
October 2012

Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery.

ACS Nano 2012 Sep 30;6(9):8041-51. Epub 2012 Aug 30.

Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

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http://pubs.acs.org/doi/10.1021/nn302639r
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http://dx.doi.org/10.1021/nn302639rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475723PMC
September 2012

Engineering nano- and microparticles to tune immunity.

Adv Mater 2012 Jul 29;24(28):3724-46. Epub 2012 May 29.

Dept. of Materials Science and Eng., Massachusetts Institute of Technology-MIT, Cambridge, MA, USA.

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http://dx.doi.org/10.1002/adma.201200446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786137PMC
July 2012

Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine.

PLoS One 2012 6;7(2):e31472. Epub 2012 Feb 6.

Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031472PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273465PMC
June 2012

The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude.

J Immunol 2012 May;188(9):4135-40

Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.4049/jimmunol.1102661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334329PMC
May 2012

Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine.

J Control Release 2012 Feb 24;157(3):354-65. Epub 2011 Jul 24.

Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139-4307, USA.

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http://dx.doi.org/10.1016/j.jconrel.2011.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811132PMC
February 2012

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.

Proc Natl Acad Sci U S A 2012 Jan 12;109(4):1080-5. Epub 2012 Jan 12.

Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1112648109
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http://dx.doi.org/10.1073/pnas.1112648109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268296PMC
January 2012

CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma.

J Immunol 2011 Dec 9;187(12):6197-207. Epub 2011 Nov 9.

Pulmonary and Critical Care Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.4049/jimmunol.1101348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237896PMC
December 2011

Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells.

Proc Natl Acad Sci U S A 2011 Aug 22;108(35):14602-7. Epub 2011 Aug 22.

Department of Microbiology and Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1109806108
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http://dx.doi.org/10.1073/pnas.1109806108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167500PMC
August 2011

Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations.

J Immunol 2010 Oct 22;185(8):4705-13. Epub 2010 Sep 22.

Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1002276
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510669PMC
October 2010

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles.

Nat Med 2010 Sep 15;16(9):1035-41. Epub 2010 Aug 15.

Department of Material Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm.2198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935928PMC
September 2010

On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands.

Annu Rev Immunol 2010 ;28:275-94

Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, 55455, USA.

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http://www.annualreviews.org/doi/10.1146/annurev-immunol-030
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http://dx.doi.org/10.1146/annurev-immunol-030409-101253DOI Listing
May 2010

Covalently-immobilized vascular endothelial growth factor promotes endothelial cell tubulogenesis in poly(ethylene glycol) diacrylate hydrogels.

J Biomater Sci Polym Ed 2009 ;20(12):1763-79

Department of Bioengineering, Rice University, Houston, TX 77005, USA.

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http://dx.doi.org/10.1163/156856208X386381DOI Listing
November 2009

Tracking the dynamics of salmonella specific T cell responses.

Curr Top Microbiol Immunol 2009 ;334:179-98

Department of Microbiology, Center for Immunology, University of Minnesota Medical, Minneapolis, MN 55455, USA.

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http://link.springer.com/10.1007/978-3-540-93864-4_8
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http://dx.doi.org/10.1007/978-3-540-93864-4_8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732114PMC
September 2009

Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire.

Proc Natl Acad Sci U S A 2009 Jul 18;106(27):11241-5. Epub 2009 Jun 18.

Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0902015106
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708705PMC
July 2009

Tracking epitope-specific T cells.

Nat Protoc 2009 ;4(4):565-81

Department of Microbiology and Center for Immunology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1038/nprot.2009.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517879PMC
June 2009

Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles.

Biomacromolecules 2009 Apr;10(4):756-65

Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://pubs.acs.org/doi/abs/10.1021/bm801199z
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769516PMC
April 2009

Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin.

Immunity 2009 Feb 5;30(2):277-88. Epub 2009 Feb 5.

Department of Microbiology and Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.immuni.2008.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770245PMC
February 2009

EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells.

Int J Nanomedicine 2008 ;3(3):351-8

Department of Bioengineering, Rice University, Houston, TX 77251-1892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626934PMC
December 2008

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration.

Biomaterials 2008 Jul 22;29(20):2962-8. Epub 2008 Apr 22.

Department of Bioengineering, Rice University, Houston, Texas, TX 77251-1892, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S014296120800229
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http://dx.doi.org/10.1016/j.biomaterials.2008.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942083PMC
July 2008

Vascularization of engineered tissues: approaches to promote angio-genesis in biomaterials.

Curr Top Med Chem 2008 ;8(4):300-10

Department of Bioengineering, Rice University, P.O. Box 1892, MS 142, Houston, Texas 77251-1892, USA.

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http://dx.doi.org/10.2174/156802608783790983DOI Listing
May 2008

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

Immunity 2008 Jan;28(1):112-21

Department of Laboratory Medicine and Pathology, Center for Immunology, The Cancer Center, University of Minnesota, 312 Church Street SE, 6-116 Nils Hasselmo Hall, Minneapolis, MN 55455 USA.

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http://dx.doi.org/10.1016/j.immuni.2007.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430111PMC
January 2008

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

Immunity 2007 Aug 16;27(2):203-13. Epub 2007 Aug 16.

Department of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.immuni.2007.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200089PMC
August 2007

Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration.

Biomaterials 2007 Jul 14;28(20):3163-70. Epub 2007 Mar 14.

Department of Bioengineering, Rice University, P.O. Box 1892, MS 142, Houston, TX 77251-1892, USA.

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July 2007

Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1.

Science 2007 May;316(5825):754-8

Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1126/science.1137895DOI Listing
May 2007

Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis.

Biomacromolecules 2007 Jan;8(1):42-9

Department of Bioengineering, Rice University, P.O. Box 1892, MS 142, Houston, Texas 77251-1892, USA.

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http://dx.doi.org/10.1021/bm060452pDOI Listing
January 2007

Photolithographic patterning of polyethylene glycol hydrogels.

Biomaterials 2006 Apr 20;27(12):2519-24. Epub 2005 Dec 20.

Department of Bioengineering, Rice University, 6100 Main Street/MS 142, Houston, TX 77005, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2005.11.045DOI Listing
April 2006

Naive and memory CD4+ T cell survival controlled by clonal abundance.

Science 2006 Apr 2;312(5770):114-6. Epub 2006 Mar 2.

Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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April 2006