Publications by authors named "James J Lee"

100Publications

The UPMC Hillman Cancer Center Approach to the Management of Colorectal Cancer During the COVID-19 Pandemic Era.

Clin Colorectal Cancer 2020 09 9;19(3):146-148. Epub 2020 Jul 9.

Division of Hematology-Oncology, Department of Medicine, Cancer Therapeutics Program, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2020.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347322PMC
September 2020

Eosinophil accumulation in postnatal lung is specific to the primary septation phase of development.

Sci Rep 2020 03 10;10(1):4425. Epub 2020 Mar 10.

Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/s41598-020-61420-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064572PMC
March 2020

Minnesota Center for Twin and Family Research.

Twin Res Hum Genet 2019 12 3;22(6):746-752. Epub 2019 Dec 3.

Department of Psychology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1017/thg.2019.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056536PMC
December 2019

The role of parental genotype in predicting offspring years of education: evidence for genetic nurture.

Mol Psychiatry 2019 Aug 23. Epub 2019 Aug 23.

Department of Psychology, University of Minnesota Twin Cities, 75 East River Parkway, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1038/s41380-019-0494-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061492PMC
August 2019

Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis.

J Clin Invest 2019 07 2;129(8):3224-3235. Epub 2019 Jul 2.

Gastrointestinal Eosinophilic Diseases Program, Department of Pediatrics, University of Colorado School of Medicine; Digestive Health Institute, Children's Hospital Colorado; Aurora, Colorado, USA.

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http://dx.doi.org/10.1172/JCI126744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668670PMC
July 2019

A phase 1b study evaluating the safety and pharmacokinetics of regorafenib in combination with cetuximab in patients with advanced solid tumors.

Int J Cancer 2019 11 14;145(9):2450-2458. Epub 2019 Jun 14.

Division of Medical Oncology, University of Southern California/Norris Comprehensive Center, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.32317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771657PMC
November 2019

Eosinophil peroxidase, GATA3, and T-bet as tissue biomarkers in chronic rhinosinusitis.

J Allergy Clin Immunol 2019 06 8;143(6):2284-2287.e6. Epub 2019 Feb 8.

Department of Otolaryngology, Mayo Clinic, Phoenix, Ariz; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic, Scottsdale, Ariz; Division of Pulmonology, Phoenix Children's Hospital, Phoenix, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.038DOI Listing
June 2019

Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer.

Cancer Immunol Res 2019 03 21;7(3):388-400. Epub 2019 Jan 21.

Department of Clinical Microbiology and Immunology, the Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0494DOI Listing
March 2019

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

Nat Genet 2019 02 14;51(2):245-257. Epub 2019 Jan 14.

Department of Economics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41588-018-0309-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713272PMC
February 2019

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Authors:
Mengzhen Liu Yu Jiang Robbee Wedow Yue Li David M Brazel Fang Chen Gargi Datta Jose Davila-Velderrain Daniel McGuire Chao Tian Xiaowei Zhan Hélène Choquet Anna R Docherty Jessica D Faul Johanna R Foerster Lars G Fritsche Maiken Elvestad Gabrielsen Scott D Gordon Jeffrey Haessler Jouke-Jan Hottenga Hongyan Huang Seon-Kyeong Jang Philip R Jansen Yueh Ling Reedik Mägi Nana Matoba George McMahon Antonella Mulas Valeria Orrù Teemu Palviainen Anita Pandit Gunnar W Reginsson Anne Heidi Skogholt Jennifer A Smith Amy E Taylor Constance Turman Gonneke Willemsen Hannah Young Kendra A Young Gregory J M Zajac Wei Zhao Wei Zhou Gyda Bjornsdottir Jason D Boardman Michael Boehnke Dorret I Boomsma Chu Chen Francesco Cucca Gareth E Davies Charles B Eaton Marissa A Ehringer Tõnu Esko Edoardo Fiorillo Nathan A Gillespie Daniel F Gudbjartsson Toomas Haller Kathleen Mullan Harris Andrew C Heath John K Hewitt Ian B Hickie John E Hokanson Christian J Hopfer David J Hunter William G Iacono Eric O Johnson Yoichiro Kamatani Sharon L R Kardia Matthew C Keller Manolis Kellis Charles Kooperberg Peter Kraft Kenneth S Krauter Markku Laakso Penelope A Lind Anu Loukola Sharon M Lutz Pamela A F Madden Nicholas G Martin Matt McGue Matthew B McQueen Sarah E Medland Andres Metspalu Karen L Mohlke Jonas B Nielsen Yukinori Okada Ulrike Peters Tinca J C Polderman Danielle Posthuma Alexander P Reiner John P Rice Eric Rimm Richard J Rose Valgerdur Runarsdottir Michael C Stallings Alena Stančáková Hreinn Stefansson Khanh K Thai Hilary A Tindle Thorarinn Tyrfingsson Tamara L Wall David R Weir Constance Weisner John B Whitfield Bendik Slagsvold Winsvold Jie Yin Luisa Zuccolo Laura J Bierut Kristian Hveem James J Lee Marcus R Munafò Nancy L Saccone Cristen J Willer Marilyn C Cornelis Sean P David David A Hinds Eric Jorgenson Jaakko Kaprio Jerry A Stitzel Kari Stefansson Thorgeir E Thorgeirsson Gonçalo Abecasis Dajiang J Liu Scott Vrieze

Nat Genet 2019 02 14;51(2):237-244. Epub 2019 Jan 14.

Department of Psychology, University of Minnesota Twin Cities, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41588-018-0307-5
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http://dx.doi.org/10.1038/s41588-018-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358542PMC
February 2019

A phase 2 trial of regorafenib as a single agent in patients with chemotherapy-refractory, advanced, and metastatic biliary tract adenocarcinoma.

Cancer 2019 03 18;125(6):902-909. Epub 2018 Dec 18.

National Institute for Occupational Safety and Health (NIOSH) Research Branch, Centers for Disease Control and Prevention, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.31872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402964PMC
March 2019

Author Correction: Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2.

Cell Death Differ 2019 Sep;26(9):1859-1860

Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, Zhejiang, China.

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http://dx.doi.org/10.1038/s41418-018-0247-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748119PMC
September 2019

Exploring the genetic correlations of antisocial behaviour and life history traits.

BJPsych Open 2018 Nov 5;4(6):467-470. Epub 2018 Nov 5.

Associate Professor of Criminology and Criminal Justice, Department of Epidemiology and Department of Family and Community Medicine, Saint Louis University, USA.

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http://dx.doi.org/10.1192/bjo.2018.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235975PMC
November 2018

Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia.

J Allergy Clin Immunol 2019 03 14;143(3):1237-1240.e2. Epub 2018 Nov 14.

Section of Pediatric Gastroenterology, Hepatology and Nutrition, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colo; Gastrointestinal Eosinophilic Diseases Program, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colo; Institute of Immunology, Department of Biology, Maynooth University, Maynooth, Ireland.

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http://dx.doi.org/10.1016/j.jaci.2018.10.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408974PMC
March 2019

Spheroid Culture of Human Pancreatic Ductal Cells to Reconstitute Development of Pancreatic Intraepithelial Neoplasia.

Methods Mol Biol 2019 ;1882:63-71

Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8879-2_6DOI Listing
June 2019

ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer.

Clin Colorectal Cancer 2018 12 13;17(4):255-257. Epub 2018 Sep 13.

Department of Medicine, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA.

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https://linkinghub.elsevier.com/retrieve/pii/S15330028183043
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http://dx.doi.org/10.1016/j.clcc.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561466PMC
December 2018

Free Will, Determinism, and Intuitive Judgments About the Heritability of Behavior.

Behav Genet 2019 03 12;49(2):136-153. Epub 2018 Oct 12.

Department of Psychology, University of Minnesota Twin Cities, 75 East River Rd., Minneapolis, MN, 55455, USA.

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http://link.springer.com/10.1007/s10519-018-9931-1
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http://dx.doi.org/10.1007/s10519-018-9931-1DOI Listing
March 2019

The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies.

Genet Epidemiol 2018 12 24;42(8):783-795. Epub 2018 Sep 24.

Mathematical Biology Section, Laboratory of Biological Modeling, NIDDK, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/gepi.22161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758917PMC
December 2018

The Adjuvant Treatment of Stage III Colon Cancer: Might Less Be More?

Oncology (Williston Park) 2018 09;32(9):437-42, 444

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September 2018

The genetics of human fertility.

Curr Opin Psychol 2019 06 13;27:41-45. Epub 2018 Aug 13.

Department of Psychology, University of Minnesota Twin Cities, 75 East River Parkway, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.copsyc.2018.07.011DOI Listing
June 2019

Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non-MSI-H Metastatic Colorectal Cancer.

Clin Colorectal Cancer 2018 12 21;17(4):258-273. Epub 2018 Jun 21.

Division of Hematology-Oncology, Department of Medicine, Cancer Therapeutics Program, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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https://linkinghub.elsevier.com/retrieve/pii/S15330028183027
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http://dx.doi.org/10.1016/j.clcc.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612427PMC
December 2018

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

Nat Genet 2018 07 23;50(8):1112-1121. Epub 2018 Jul 23.

National Bureau of Economic Research, Cambridge, MA, USA.

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http://www.nature.com/articles/s41588-018-0147-3
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http://dx.doi.org/10.1038/s41588-018-0147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393768PMC
July 2018

Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease.

J Leukoc Biol 2018 07 14;104(1):95-108. Epub 2018 Apr 14.

Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://doi.wiley.com/10.1002/JLB.1MR1117-442RR
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http://dx.doi.org/10.1002/JLB.1MR1117-442RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013365PMC
July 2018

Inhibiting focal adhesion kinase (FAK) blocks IL-4 induced VCAM-1 expression and eosinophil recruitment in vitro and in vivo.

J Leukoc Biol 2018 07 6;104(1):147-158. Epub 2018 Apr 6.

Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1002/JLB.3MA1117-429RDOI Listing
July 2018

Frontline Science: Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils.

J Leukoc Biol 2018 07 30;104(1):11-19. Epub 2018 Mar 30.

Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/JLB.2HI0917-391RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013361PMC
July 2018

Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease.

J Allergy Clin Immunol 2018 05 31;141(5):1919-1921.e5. Epub 2018 Jan 31.

Digestive Health Institute, Children's Hospital of Colorado, Aurora, Colo; Gastrointestinal Eosinophilic Diseases Program, University of Colorado School of Medicine, Aurora, Colo.

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http://dx.doi.org/10.1016/j.jaci.2017.12.993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938131PMC
May 2018

Genomic data can illuminate the architecture and evolution of cognitive abilities.

Behav Brain Sci 2017 01;40:e209

Institute for Advanced Application,Geisinger Health System,Lewisburg,PA

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http://dx.doi.org/10.1017/S0140525X16002004DOI Listing
January 2017

Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis.

Cell Res 2018 Mar 12;28(3):323-335. Epub 2018 Jan 12.

Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Institute of Respiratory Diseases, Hangzhou, Zhejiang 310009, China.

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http://dx.doi.org/10.1038/cr.2018.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835778PMC
March 2018

Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid.

J Invest Dermatol 2018 05 12;138(5):1032-1043. Epub 2017 Dec 12.

Department of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531612PMC
May 2018

Throat-derived eosinophil peroxidase is not a reliable biomarker of pediatric eosinophilic esophagitis.

J Allergy Clin Immunol Pract 2017 Nov - Dec;5(6):1804-1805

Phoenix Children's Hospital, Phoenix, Ariz; Mayo Clinic Arizona, Scottsdale, Ariz; University of Arizona College of Medicine, Phoenix, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.07.043DOI Listing
May 2019

Sputum autoantibodies in patients with severe eosinophilic asthma.

J Allergy Clin Immunol 2018 04 24;141(4):1269-1279. Epub 2017 Jul 24.

Division of Respirology, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.06.033DOI Listing
April 2018

Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications.

J Allergy Clin Immunol 2018 03 15;141(3):918-926.e3. Epub 2017 Jun 15.

Department of Medicine, University of Arizona, Tucson, Ariz; Department of Immunobiology, University of Arizona, Tucson, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732097PMC
March 2018

Adjuvant Chemotherapy for Stage II Colon Cancer: The Debate Goes On.

J Oncol Pract 2017 04;13(4):245-246

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JOP.2017.022178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455155PMC
April 2017

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.

J Immunol 2017 04 10;198(8):3214-3226. Epub 2017 Mar 10.

Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103.

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http://dx.doi.org/10.4049/jimmunol.1600787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384374PMC
April 2017

Adherence, Dosing, and Managing Toxicities With Trifluridine/Tipiracil (TAS-102).

Clin Colorectal Cancer 2017 06 25;16(2):85-92. Epub 2017 Jan 25.

Division of Hematology-Oncology, Department of Medicine, Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.clcc.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743195PMC
June 2017

Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation.

Am J Respir Crit Care Med 2017 05;195(10):1321-1332

3 Division of Hematology/Oncology, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona, Scottsdale, Arizona.

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http://dx.doi.org/10.1164/rccm.201606-1129OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443899PMC
May 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G William Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 11;48(12):1591

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http://dx.doi.org/10.1038/ng1216-1587bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509058PMC
November 2016

Induction of Airway Allergic Inflammation by Hypothiocyanite via Epithelial Cells.

J Biol Chem 2016 12 18;291(53):27219-27227. Epub 2016 Nov 18.

From the Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga 849-8501, Japan and

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http://dx.doi.org/10.1074/jbc.M116.746909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207149PMC
December 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Authors:
Nicola Barban Rick Jansen Ronald de Vlaming Ahmad Vaez Jornt J Mandemakers Felix C Tropf Xia Shen James F Wilson Daniel I Chasman Ilja M Nolte Vinicius Tragante Sander W van der Laan John R B Perry Augustine Kong Tarunveer S Ahluwalia Eva Albrecht Laura Yerges-Armstrong Gil Atzmon Kirsi Auro Kristin Ayers Andrew Bakshi Danny Ben-Avraham Klaus Berger Aviv Bergman Lars Bertram Lawrence F Bielak Gyda Bjornsdottir Marc Jan Bonder Linda Broer Minh Bui Caterina Barbieri Alana Cavadino Jorge E Chavarro Constance Turman Maria Pina Concas Heather J Cordell Gail Davies Peter Eibich Nicholas Eriksson Tõnu Esko Joel Eriksson Fahimeh Falahi Janine F Felix Mark Alan Fontana Lude Franke Ilaria Gandin Audrey J Gaskins Christian Gieger Erica P Gunderson Xiuqing Guo Caroline Hayward Chunyan He Edith Hofer Hongyan Huang Peter K Joshi Stavroula Kanoni Robert Karlsson Stefan Kiechl Annette Kifley Alexander Kluttig Peter Kraft Vasiliki Lagou Cecile Lecoeur Jari Lahti Ruifang Li-Gao Penelope A Lind Tian Liu Enes Makalic Crysovalanto Mamasoula Lindsay Matteson Hamdi Mbarek Patrick F McArdle George McMahon S Fleur W Meddens Evelin Mihailov Mike Miller Stacey A Missmer Claire Monnereau Peter J van der Most Ronny Myhre Mike A Nalls Teresa Nutile Ioanna Panagiota Kalafati Eleonora Porcu Inga Prokopenko Kumar B Rajan Janet Rich-Edwards Cornelius A Rietveld Antonietta Robino Lynda M Rose Rico Rueedi Kathleen A Ryan Yasaman Saba Daniel Schmidt Jennifer A Smith Lisette Stolk Elizabeth Streeten Anke Tönjes Gudmar Thorleifsson Sheila Ulivi Juho Wedenoja Juergen Wellmann Peter Willeit Jie Yao Loic Yengo Jing Hua Zhao Wei Zhao Daria V Zhernakova Najaf Amin Howard Andrews Beverley Balkau Nir Barzilai Sven Bergmann Ginevra Biino Hans Bisgaard Klaus Bønnelykke Dorret I Boomsma Julie E Buring Harry Campbell Stefania Cappellani Marina Ciullo Simon R Cox Francesco Cucca Daniela Toniolo George Davey-Smith Ian J Deary George Dedoussis Panos Deloukas Cornelia M van Duijn Eco J C de Geus Johan G Eriksson Denis A Evans Jessica D Faul Cinzia Felicita Sala Philippe Froguel Paolo Gasparini Giorgia Girotto Hans-Jörgen Grabe Karin Halina Greiser Patrick J F Groenen Hugoline G de Haan Johannes Haerting Tamara B Harris Andrew C Heath Kauko Heikkilä Albert Hofman Georg Homuth Elizabeth G Holliday John Hopper Elina Hyppönen Bo Jacobsson Vincent W V Jaddoe Magnus Johannesson Astanand Jugessur Mika Kähönen Eero Kajantie Sharon L R Kardia Bernard Keavney Ivana Kolcic Päivikki Koponen Peter Kovacs Florian Kronenberg Zoltan Kutalik Martina La Bianca Genevieve Lachance William G Iacono Sandra Lai Terho Lehtimäki David C Liewald Cecilia M Lindgren Yongmei Liu Robert Luben Michael Lucht Riitta Luoto Per Magnus Patrik K E Magnusson Nicholas G Martin Matt McGue Ruth McQuillan Sarah E Medland Christa Meisinger Dan Mellström Andres Metspalu Michela Traglia Lili Milani Paul Mitchell Grant W Montgomery Dennis Mook-Kanamori Renée de Mutsert Ellen A Nohr Claes Ohlsson Jørn Olsen Ken K Ong Lavinia Paternoster Alison Pattie Brenda W J H Penninx Markus Perola Patricia A Peyser Mario Pirastu Ozren Polasek Chris Power Jaakko Kaprio Leslie J Raffel Katri Räikkönen Olli Raitakari Paul M Ridker Susan M Ring Kathryn Roll Igor Rudan Daniela Ruggiero Dan Rujescu Veikko Salomaa David Schlessinger Helena Schmidt Reinhold Schmidt Nicole Schupf Johannes Smit Rossella Sorice Tim D Spector John M Starr Doris Stöckl Konstantin Strauch Michael Stumvoll Morris A Swertz Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Joyce Y Tung André G Uitterlinden Simona Vaccargiu Jorma Viikari Veronique Vitart Henry Völzke Peter Vollenweider Dragana Vuckovic Johannes Waage Gert G Wagner Jie Jin Wang Nicholas J Wareham David R Weir Gonneke Willemsen Johann Willeit Alan F Wright Krina T Zondervan Kari Stefansson Robert F Krueger James J Lee Daniel J Benjamin David Cesarini Philipp D Koellinger Marcel den Hoed Harold Snieder Melinda C Mills

Nat Genet 2016 12 31;48(12):1462-1472. Epub 2016 Oct 31.

Department of Sociology and Nuffield College, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695684PMC
December 2016

Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma.

J Biol Chem 2016 Oct 1;291(42):22118-22135. Epub 2016 Sep 1.

From the Departments of Cellular and Molecular Medicine, Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195,

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http://dx.doi.org/10.1074/jbc.M116.750034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063994PMC
October 2016

SiglecF+Gr1hi eosinophils are a distinct subpopulation within the lungs of allergen-challenged mice.

J Leukoc Biol 2017 01 16;101(1):321-328. Epub 2016 Aug 16.

Inflammation Immunobiology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA;

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http://dx.doi.org/10.1189/jlb.3A0416-166RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166438PMC
January 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G Iacono Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 07;48(8):970

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July 2016

Genome-wide association study identifies 74 loci associated with educational attainment.

Authors:
Aysu Okbay Jonathan P Beauchamp Mark Alan Fontana James J Lee Tune H Pers Cornelius A Rietveld Patrick Turley Guo-Bo Chen Valur Emilsson S Fleur W Meddens Sven Oskarsson Joseph K Pickrell Kevin Thom Pascal Timshel Ronald de Vlaming Abdel Abdellaoui Tarunveer S Ahluwalia Jonas Bacelis Clemens Baumbach Gyda Bjornsdottir Johannes H Brandsma Maria Pina Concas Jaime Derringer Nicholas A Furlotte Tessel E Galesloot Giorgia Girotto Richa Gupta Leanne M Hall Sarah E Harris Edith Hofer Momoko Horikoshi Jennifer E Huffman Kadri Kaasik Ioanna P Kalafati Robert Karlsson Augustine Kong Jari Lahti Sven J van der Lee Christiaan deLeeuw Penelope A Lind Karl-Oskar Lindgren Tian Liu Massimo Mangino Jonathan Marten Evelin Mihailov Michael B Miller Peter J van der Most Christopher Oldmeadow Antony Payton Natalia Pervjakova Wouter J Peyrot Yong Qian Olli Raitakari Rico Rueedi Erika Salvi Börge Schmidt Katharina E Schraut Jianxin Shi Albert V Smith Raymond A Poot Beate St Pourcain Alexander Teumer Gudmar Thorleifsson Niek Verweij Dragana Vuckovic Juergen Wellmann Harm-Jan Westra Jingyun Yang Wei Zhao Zhihong Zhu Behrooz Z Alizadeh Najaf Amin Andrew Bakshi Sebastian E Baumeister Ginevra Biino Klaus Bønnelykke Patricia A Boyle Harry Campbell Francesco P Cappuccio Gail Davies Jan-Emmanuel De Neve Panos Deloukas Ilja Demuth Jun Ding Peter Eibich Lewin Eisele Niina Eklund David M Evans Jessica D Faul Mary F Feitosa Andreas J Forstner Ilaria Gandin Bjarni Gunnarsson Bjarni V Halldórsson Tamara B Harris Andrew C Heath Lynne J Hocking Elizabeth G Holliday Georg Homuth Michael A Horan Jouke-Jan Hottenga Philip L de Jager Peter K Joshi Astanand Jugessur Marika A Kaakinen Mika Kähönen Stavroula Kanoni Liisa Keltigangas-Järvinen Lambertus A L M Kiemeney Ivana Kolcic Seppo Koskinen Aldi T Kraja Martin Kroh Zoltan Kutalik Antti Latvala Lenore J Launer Maël P Lebreton Douglas F Levinson Paul Lichtenstein Peter Lichtner David C M Liewald Anu Loukola Pamela A Madden Reedik Mägi Tomi Mäki-Opas Riccardo E Marioni Pedro Marques-Vidal Gerardus A Meddens George McMahon Christa Meisinger Thomas Meitinger Yusplitri Milaneschi Lili Milani Grant W Montgomery Ronny Myhre Christopher P Nelson Dale R Nyholt William E R Ollier Aarno Palotie Lavinia Paternoster Nancy L Pedersen Katja E Petrovic David J Porteous Katri Räikkönen Susan M Ring Antonietta Robino Olga Rostapshova Igor Rudan Aldo Rustichini Veikko Salomaa Alan R Sanders Antti-Pekka Sarin Helena Schmidt Rodney J Scott Blair H Smith Jennifer A Smith Jan A Staessen Elisabeth Steinhagen-Thiessen Konstantin Strauch Antonio Terracciano Martin D Tobin Sheila Ulivi Simona Vaccargiu Lydia Quaye Frank J A van Rooij Cristina Venturini Anna A E Vinkhuyzen Uwe Völker Henry Völzke Judith M Vonk Diego Vozzi Johannes Waage Erin B Ware Gonneke Willemsen John R Attia David A Bennett Klaus Berger Lars Bertram Hans Bisgaard Dorret I Boomsma Ingrid B Borecki Ute Bültmann Christopher F Chabris Francesco Cucca Daniele Cusi Ian J Deary George V Dedoussis Cornelia M van Duijn Johan G Eriksson Barbara Franke Lude Franke Paolo Gasparini Pablo V Gejman Christian Gieger Hans-Jörgen Grabe Jacob Gratten Patrick J F Groenen Vilmundur Gudnason Pim van der Harst Caroline Hayward David A Hinds Wolfgang Hoffmann Elina Hyppönen William G Iacono Bo Jacobsson Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Terho Lehtimäki Steven F Lehrer Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Neil Pendleton Brenda W J H Penninx Markus Perola Nicola Pirastu Mario Pirastu Ozren Polasek Danielle Posthuma Christine Power Michael A Province Nilesh J Samani David Schlessinger Reinhold Schmidt Thorkild I A Sørensen Tim D Spector Kari Stefansson Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier Joyce Y Tung André G Uitterlinden Veronique Vitart Peter Vollenweider David R Weir James F Wilson Alan F Wright Dalton C Conley Robert F Krueger George Davey Smith Albert Hofman David I Laibson Sarah E Medland Michelle N Meyer Jian Yang Magnus Johannesson Peter M Visscher Tõnu Esko Philipp D Koellinger David Cesarini Daniel J Benjamin

Nature 2016 05 11;533(7604):539-42. Epub 2016 May 11.

Center for Economic and Social Research, University of Southern California, Los Angeles, California 90089-3332, USA.

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http://dx.doi.org/10.1038/nature17671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883595PMC
May 2016

Therapeutic drug monitoring of 5-fluorouracil.

Cancer Chemother Pharmacol 2016 09 23;78(3):447-64. Epub 2016 May 23.

Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, 5150 Centre Ave., Fifth Floor, Pittsburgh, PA, 15232, USA.

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http://dx.doi.org/10.1007/s00280-016-3054-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204259PMC
September 2016

Phase I study of safety and tolerability of sunitinib in combination with sirolimus in patients with refractory solid malignancies and determination of VEGF (VEGF-A) and soluble VEGF-R2 (sVEGFR2) in plasma.

Cancer Chemother Pharmacol 2016 06 21;77(6):1193-200. Epub 2016 Apr 21.

Division of Hematology/Oncology, Department of Medicine, Tufts Medical Center Cancer Center, Boston, MA, 02111, USA.

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http://dx.doi.org/10.1007/s00280-016-3033-7DOI Listing
June 2016

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G Iacono Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 06 18;48(6):624-33. Epub 2016 Apr 18.

Department of Economics, New York University, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.3552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884152PMC
June 2016

Uncovering the Genetic Architectures of Quantitative Traits.

Comput Struct Biotechnol J 2016 23;14:28-34. Epub 2015 Nov 23.

Mathematical Biology Section, NIDDK/LBM, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.csbj.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816193PMC
April 2016

Options for Second-Line Treatment in Metastatic Colorectal Cancer.

Clin Adv Hematol Oncol 2016 Jan;14(1):46-54

The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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January 2016

Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus.

Am J Respir Cell Mol Biol 2016 09;55(3):387-94

1 Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.

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http://dx.doi.org/10.1165/rcmb.2015-0405OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023029PMC
September 2016

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.

Am J Pathol 2016 Apr 22;186(4):885-98. Epub 2016 Feb 22.

Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807926PMC
April 2016

Why Behavioral Genetics Matters: Comment on Plomin et al. (2016).

Perspect Psychol Sci 2016 Jan;11(1):29-30

Department of Psychology, University of Minnesota Twin Cities.

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http://dx.doi.org/10.1177/1745691615611932DOI Listing
January 2016

Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry.

Cancer Chemother Pharmacol 2016 Mar 19;77(3):515-26. Epub 2016 Jan 19.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Hillman Research Pavilion, Suite G27E, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1007/s00280-016-2965-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767595PMC
March 2016

Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury.

PLoS Pathog 2015 Dec 31;11(12):e1005347. Epub 2015 Dec 31.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697774PMC
December 2015

Eosinophils and IL-33 Perpetuate Chronic Inflammation and Fibrosis in a Pediatric Population with Stricturing Crohn's Ileitis.

Inflamm Bowel Dis 2015 Oct;21(10):2429-40

*Section of Pediatric Gastroenterology, Hepatology and Nutrition, Gastrointestinal Eosinophilic Diseases Program, Department of Pediatrics and Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado; †Department of Medicine, Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, Colorado; ‡University of Colorado School of Medicine, Aurora, Colorado; §Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado; ‖Department of Anesthesiology, University of Colorado School of Medicine, Aurora, Colorado; and ¶Department of Biochemistry and Molecular Biology, Mayo Clinic Scottsdale, Azusa, California.

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http://dx.doi.org/10.1097/MIB.0000000000000512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567482PMC
October 2015

KRAS Status as an Independent Prognostic Factor for Survival after Yttrium-90 Radioembolization Therapy for Unresectable Colorectal Cancer Liver Metastases.

J Vasc Interv Radiol 2015 Aug;26(8):1102-11

Division of Interventional Radiology, Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.. Electronic address:

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http://dx.doi.org/10.1016/j.jvir.2015.05.032DOI Listing
August 2015

Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease.

J Allergy Clin Immunol 2015 Jun;135(6):1519-28.e8

Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, Ohio; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460579PMC
June 2015

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

N Engl J Med 2015 Jun 30;372(26):2509-20. Epub 2015 May 30.

From the Swim Across America Laboratory (D.T.L., J.N.U., B.R.B., L.A.D.), Sidney Kimmel Comprehensive Cancer Center (D.T.L., J.N.U., H.W., H.K., A.D.E., A.D.S., B.S.L., N.S.A., D.L., B.B., R.C.D., D.M.P., N.P., K.W.K., S.Z., B.V., L.A.D.), Ludwig Center and Howard Hughes Medical Institute (B.R.B., A.D.S., N.P., K.W.K., S.Z., B.V., L.A.D.), and the Departments of Radiology (A.Z.) and Pathology (F.B., T.H., R.H.H., L.D.W., N.C., T.C.C., J.M.T., R.A.A., J.R.E.), Johns Hopkins University School of Medicine, Baltimore; Department of Medicine, Stanford University School of Medicine, Stanford, CA (G.A.F.); Providence Cancer Center at Providence Health and Services, Portland, OR (T.S.C.); Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh (J.J.L.); Bon Secours Cancer Institute, Richmond, VA (S.M.D.); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center-James Cancer Center and Solove Research Institute, and Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus (R.M.G., A.C.); and Merck, Kenilworth, NJ, and North Wales, PA (M.K.).

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http://dx.doi.org/10.1056/NEJMoa1500596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481136PMC
June 2015

Thickness-Dependent Coherent Phonon Frequency in Ultrathin FeSe/SrTiO₃ Films.

Nano Lett 2015 Jun 1;15(6):4150-4. Epub 2015 Jun 1.

†Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, United States.

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June 2015

Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture.

PLoS One 2015 11;10(5):e0126846. Epub 2015 May 11.

The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, Tempe, Arizona, United States of America; School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427280PMC
February 2016

Second-generation PLINK: rising to the challenge of larger and richer datasets.

Gigascience 2015 25;4. Epub 2015 Feb 25.

Mathematical Biology Section, NIDDK/LBM, National Institutes of Health, Bethesda, 20892 MD USA ; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, 55455 MN USA.

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http://dx.doi.org/10.1186/s13742-015-0047-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342193PMC
December 2016

Eosinophils mediate protective immunity against secondary nematode infection.

J Immunol 2015 Jan 26;194(1):283-90. Epub 2014 Nov 26.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853;

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http://dx.doi.org/10.4049/jimmunol.1402219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272919PMC
January 2015

Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge.

J Allergy Clin Immunol 2015 Feb 11;135(2):451-60. Epub 2014 Oct 11.

Division of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587899PMC
February 2015

Eosinophil-derived IL-10 supports chronic nematode infection.

J Immunol 2014 Oct 10;193(8):4178-87. Epub 2014 Sep 10.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1400852
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http://dx.doi.org/10.4049/jimmunol.1400852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241261PMC
October 2014

Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis.

Gut 2015 Aug 10;64(8):1236-47. Epub 2014 Sep 10.

Section of Pediatric Gastroenterology, Hepatology and Nutrition, Gastrointestinal Eosinophilic Diseases Program, Department of Pediatrics; Digestive Health Institute, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, Colorado, USA University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1136/gutjnl-2014-306998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515997PMC
August 2015