James J Hsieh

James J Hsieh

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James J Hsieh

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Chromophobe Renal Cell Carcinoma: Results From a Large Single-Institution Series.

Clin Genitourin Cancer 2019 Jun 26. Epub 2019 Jun 26.

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2019.06.011DOI Listing
June 2019

Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics.

Anal Cell Pathol (Amst) 2018 10;2018:2898962. Epub 2018 Dec 10.

Interventional Radiology Section, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1155/2018/2898962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311765PMC
April 2019

Linking Binary Gene Relationships to Drivers of Renal Cell Carcinoma Reveals Convergent Function in Alternate Tumor Progression Paths.

Sci Rep 2019 Feb 27;9(1):2899. Epub 2019 Feb 27.

Clemson University Department of Genetics & Biochemistry, Clemson, SC, USA.

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http://dx.doi.org/10.1038/s41598-019-39875-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393532PMC
February 2019

Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.

J Clin Oncol 2018 Oct 29:JCO2018792549. Epub 2018 Oct 29.

James J. Hsieh, Valerie H. Le, and Toshinao Oyama, Washington University, St Louis, MO; Christopher J. Ricketts, National Institutes of Health, Bethesda, MA; Thai Huu Ho, Mayo Clinic, Phoenix, AZ; and Emily H. Cheng, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2018.79.2549
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http://dx.doi.org/10.1200/JCO.2018.79.2549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299341PMC
October 2018

Plasma Glycosaminoglycans as Diagnostic and Prognostic Biomarkers in Surgically Treated Renal Cell Carcinoma.

Eur Urol Oncol 2018 10 13;1(5):364-377. Epub 2018 Jun 13.

Department of Biology and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.euo.2018.04.015DOI Listing
October 2018

KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function.

Oncogene 2018 08 14;37(34):4692-4710. Epub 2018 May 14.

Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1038/s41388-018-0273-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107480PMC
August 2018

Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.

J Clin Oncol 2018 Oct 29:JCO2018792549. Epub 2018 Oct 29.

James J. Hsieh, Valerie H. Le, and Toshinao Oyama, Washington University, St Louis, MO; Christopher J. Ricketts, National Institutes of Health, Bethesda, MA; Thai Huu Ho, Mayo Clinic, Phoenix, AZ; and Emily H. Cheng, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2018.79.2549
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http://dx.doi.org/10.1200/JCO.2018.79.2549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299341PMC
October 2018

In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of F-(2S,4R)-4-Fluoroglutamine.

Radiology 2018 05 31;287(2):667-675. Epub 2018 Jan 31.

From the Department of Radiology (M.P.S.D., W.W., J.S.L.), Department of Medicine (J.J.H., J.B., A.M.O., J.J.H., I.K.M., J.F.G., D.P.K.), Radiochemistry and Molecular Imaging Probe Core (H.Z., E.M.B., S.K.L., J.S.L.), and Department of Medical Physics (B.J.B., P.B.Z.), Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Room S113E, New York, NY 10065; Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY (H.Z., K.S., J.S.L.); Department of Radiology, Weill-Cornell Medical College, New York, NY (M.P.S.D., W.W., J.S.L.); Laboratory of Neural Systems, the Rockefeller University, New York, NY (C.P.); Department of Pathology, University of Michigan, Ann Arbor, Mich (S.V.); and Departments of Radiology and Pharmacology, University of Pennsylvania, Philadelphia, Pa (H.F.K.).

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http://dx.doi.org/10.1148/radiol.2017162610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929369PMC
May 2018

Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision.

J Pathol 2018 04 14;244(5):525-537. Epub 2018 Feb 14.

Human Genome Sequencing Center, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1002/path.5022DOI Listing
April 2018

Are We Ready for Adjuvant Sunitinib in High-risk Renal Cell Carcinoma?

Eur Urol 2018 01 12;73(1):69-70. Epub 2017 Oct 12.

Molecular Oncology, Department of Medicine, Siteman Cancer Center, Washington University, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.eururo.2017.09.026DOI Listing
January 2018

Recommendations for the Management of Rare Kidney Cancers.

Eur Urol 2017 12 16;72(6):974-983. Epub 2017 Jul 16.

Division of Surgical Oncology, Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.06.040DOI Listing
December 2017

ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival.

Cell Rep 2017 Dec;21(10):2926-2939

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173166
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http://dx.doi.org/10.1016/j.celrep.2017.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915869PMC
December 2017

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nat Commun 2017 08 4;8(1):199. Epub 2017 Aug 4.

Dan L. Duncan Comprehensive Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-017-00289-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543131PMC
August 2017

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy.

Nat Commun 2017 07 17;8:16078. Epub 2017 Jul 17.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms16078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520052PMC
July 2017

Molecular Classification of Renal Cell Carcinoma and Its Implication in Future Clinical Practice.

Kidney Cancer 2017 Jul 26;1(1):3-13. Epub 2017 Jul 26.

Molecular Oncology, Department of Medicine, Siteman Cancer Center, Washington University, St. Louis, MO, USA.

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http://dx.doi.org/10.3233/KCA-170008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179110PMC
July 2017

SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer.

Mol Cell Oncol 2017 19;4(4):e1342747. Epub 2017 Jun 19.

Molecular Oncology, Department of Medicine, Siteman Cancer Center, Washington University, St. Louis, MO, USA.

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http://dx.doi.org/10.1080/23723556.2017.1342747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540208PMC
June 2017

Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer.

Semin Cell Dev Biol 2017 04 8;64:98-106. Epub 2016 Sep 8.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States.

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http://dx.doi.org/10.1016/j.semcdb.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522717PMC
April 2017

Renal cell carcinoma.

Nat Rev Dis Primers 2017 Mar 9;3:17009. Epub 2017 Mar 9.

Department of Experimental and Clinical Medical Sciences - Urologic Clinic, University of Udine, Udine, Italy.

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http://dx.doi.org/10.1038/nrdp.2017.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936048PMC
March 2017

A braided cancer river connects tumor heterogeneity and precision medicine.

Clin Transl Med 2016 Dec 20;5(1):42. Epub 2016 Oct 20.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.

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http://dx.doi.org/10.1186/s40169-016-0123-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073086PMC
December 2016

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.

Cancer Cell 2016 Dec 23;30(6):863-878. Epub 2016 Nov 23.

Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501282PMC
December 2016

The panoramic view of clear cell renal cell carcinoma metabolism: values of integrated global cancer metabolomics.

Transl Androl Urol 2016 Dec;5(6):984-986

Department of Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.21037/tau.2016.11.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182233PMC
December 2016

Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.

J Clin Oncol 2016 11;34(32):3846-3853

Martin H. Voss, Ying-Bei Chen, Kaitlin M. Woo, Joshua L. Chaim, Devyn T. Coskey, Almedina Redzematovic, Patricia Wang, William Lee, S. Duygu Selcuklu, Chung-Han Lee, Michael F. Berger, Satish K. Tickoo, Victor E. Reuter, Sujata Pati, James J. Hsieh, Robert J. Motzer, and Darren R. Feldman, Memorial Sloan Kettering Cancer Center; and Ana M. Molina, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.67.9084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791841PMC
November 2016

Sarcomatoid renal cell carcinoma: genomic insights from sequencing of matched sarcomatous and carcinomatous components.

Transl Cancer Res 2016 Aug;5(Suppl 2):S160-S165

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.21037/tcr.2016.07.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695716PMC
August 2016

Taspase 1: A protease with many biological surprises.

Mol Cell Oncol 2015 Oct-Dec;2(4):e999513. Epub 2015 Jan 23.

Human Oncology & Pathogenesis Program; Memorial Sloan-Kettering Cancer Center; New York, NY, USA; Department of Medicine; Memorial Sloan-Kettering Cancer Center; New York, NY, USA; Department of Medicine; Weill Medical College of Cornell University; New York, NY, USA.

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http://dx.doi.org/10.1080/23723556.2014.999513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905357PMC
June 2016

Therapeutic Guide for mTOuRing through the Braided Kidney Cancer Genomic River.

Clin Cancer Res 2016 05 26;22(10):2320-2. Epub 2016 Feb 26.

Department of Medicine, GU Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431075PMC
May 2016

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Cell Rep 2016 Mar 3;14(10):2476-89. Epub 2016 Mar 3.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794376PMC
March 2016

Bevacizumab Monotherapy as Salvage Therapy for Advanced Clear Cell Renal Cell Carcinoma Pretreated With Targeted Drugs.

Clin Genitourin Cancer 2016 Feb 7;14(1):56-62. Epub 2015 Aug 7.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2015.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965701PMC
February 2016

Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID.

Transcription 2015 ;6(2):21-32

a Marie Curie Research Institute; The Chart , Oxted , Surrey , United Kingdom.

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http://dx.doi.org/10.1080/21541264.2015.1052178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581359PMC
December 2015

A river model to map convergent cancer evolution and guide therapy in RCC.

Nat Rev Urol 2015 Dec 3;12(12):706-12. Epub 2015 Nov 3.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 353 East 68th Street, New York, NY 10065, USA.

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http://www.nature.com/articles/nrurol.2015.260
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http://dx.doi.org/10.1038/nrurol.2015.260DOI Listing
December 2015

The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis.

Cell Rep 2015 Dec 19;13(9):1895-908. Epub 2015 Nov 19.

Rutgers Cancer Institute of New Jersey (CINJ), 195 Little Albany Street, New Brunswick, NJ 08903, USA; Department of Molecular Biology and Biochemistry, Rutgers University, 604 Allison Road, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.10.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779191PMC
December 2015

Expression of Ror2 mediates invasive phenotypes in renal cell carcinoma.

PLoS One 2014 26;9(12):e116101. Epub 2014 Dec 26.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599, United States of America; Departments of Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116101PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277431PMC
November 2015

Genomic characterisation of two cancers of unknown primary cases supports a kidney cancer origin.

BMJ Case Rep 2015 Oct 22;2015. Epub 2015 Oct 22.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1136/bcr-2015-212685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620212PMC
October 2015

Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis.

Cancer Res 2015 Jun 7;75(12):2541-52. Epub 2015 May 7.

Division of Nephrology, Department of Internal Medicine, School of Medicine, University of California, Davis, California. Cancer Center, University of California, Davis, California. Medical Service, Sacramento VA Medical Center, Sacramento, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470795PMC
June 2015

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

Cell Res 2014 Nov 30;24(11):1354-66. Epub 2014 Sep 30.

1] Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA [2] Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA [3] Department of Medicine, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/cr.2014.129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220155PMC
November 2014

ClearCode34: A prognostic risk predictor for localized clear cell renal cell carcinoma.

Eur Urol 2014 Jul 25;66(1):77-84. Epub 2014 Feb 25.

UNC Lineberger Cancer Center, Chapel Hill, NC, USA; Department of Medicine, Division of Hematology and Oncology, and Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838140016
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http://dx.doi.org/10.1016/j.eururo.2014.02.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058355PMC
July 2014

A systematic review of predictive and prognostic biomarkers for VEGF-targeted therapy in renal cell carcinoma.

Cancer Treat Rev 2014 May 4;40(4):533-47. Epub 2013 Dec 4.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Medical College of Cornell University, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2013.11.008DOI Listing
May 2014

Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy.

Clin Cancer Res 2014 Apr 12;20(7):1955-64. Epub 2014 Mar 12.

Authors' Affiliations: Departments of Medicine, Surgery, Pathology, Radiology, and Computational Biology; Human Oncology and Pathogenesis Program; Genomics Core Laboratory, Memorial Sloan-Kettering Cancer Center; and Department of Medicine, Weill Medical College of Cornell University, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140619PMC
April 2014

Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4.

Cancer Cell 2014 Apr;25(4):530-42

Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097146PMC
April 2014

Novel approaches targeting the vascular endothelial growth factor axis in renal cell carcinoma.

Cancer J 2013 Jul-Aug;19(4):299-306

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://pdfs.journals.lww.com/journalppo/2013/07000/Novel_App
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PPO.0b013e31829d5cffDOI Listing
February 2014

Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations.

Radiology 2014 Feb 28;270(2):464-71. Epub 2013 Oct 28.

From the Genitourinary Imaging Group, Department of Radiology (C.A.K., P.L.D.P., J.C., H.H., O.A.), Urology Service, Department of Surgery (A.A.H., P.R.), Human Oncology & Pathogenesis Program (A.A.H., J.J.H.), Department of Epidemiology and Biostatistics (I.O.), and Department of Medicine, Genitourinary Oncology Service (R.M., J.J.H.), Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Radiology Academic Offices, Room C278, New York, NY 10065.

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http://dx.doi.org/10.1148/radiol.13130663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011179PMC
February 2014

An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma.

J Natl Cancer Inst 2013 Dec 27;105(24):1862-70. Epub 2013 Nov 27.

Affiliations of authors: Urology Service, Department of Surgery (AAH, NM, BF, PHK, PR), Human Oncology & Pathogenesis Program (AAH, JJH); Epidemiology and Biostatistics (HF, ECZ), Computational Biology (AJ, NS, GC, CS), Genitourinary Oncology (MHV, RJM, JJH), and Department of Pathology (VER), Memorial Sloan-Kettering Cancer Center, New York, NY; USC Epigenome Center, University of Southern California, Los Angeles, California (HS, PWL); Weill Medical College, Cornell University, New York, NY (RJM, JJH, PR).

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http://dx.doi.org/10.1093/jnci/djt310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866155PMC
December 2013

SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer.

Cancer Cell 2013 Dec;24(6):738-50

Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910168PMC
December 2013

Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.

Dev Cell 2013 Oct;27(2):188-200

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2013.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947863PMC
October 2013

Long-term response to sunitinib therapy for metastatic renal cell carcinoma.

Clin Genitourin Cancer 2013 Sep 24;11(3):297-302. Epub 2013 May 24.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.clgc.2013.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959735PMC
September 2013

A clear picture of renal cell carcinoma.

Nat Genet 2013 Aug;45(8):849-50

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http://dx.doi.org/10.1038/ng.2708DOI Listing
August 2013

HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.

J Clin Invest 2013 Jul 24;123(7):3154-65. Epub 2013 Jun 24.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI65566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696564PMC
July 2013

"Targeting Taspase1 for Cancer Therapy"-Response.

Cancer Res 2012 Jun;72(11):2913

Human Oncology and Pathogenesis Program Memorial Sloan-Kettering Cancer Center New York, NY, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947868PMC
June 2012

MLL fusions: pathways to leukemia.

Cancer Biol Ther 2009 Jul;8(13):1204-11

Molecular Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289713PMC
http://dx.doi.org/10.4161/cbt.8.13.8924DOI Listing
July 2009