Publications by authors named "James Galagan"

81Publications

Development and Clinical Validation of Iso-IMRS: A Novel Diagnostic Assay for Malaria.

Anal Chem 2021 Jan 19. Epub 2021 Jan 19.

Department of Biomedical Engineering, Boston University, 44 Cummington Mall, Room 702, Boston, Massachusetts 02215, United States.

View Article and Find Full Text PDF
January 2021

Transcription Factor Based Small-Molecule Sensing with a Rapid Cell Phone Enabled Fluorescent Bead Assay.

Angew Chem Int Ed Engl 2020 11 18;59(48):21597-21602. Epub 2020 Sep 18.

Division of Materials Science and Engineering, Boston University, Boston, MA, USA.

View Article and Find Full Text PDF
November 2020

Redefining fundamental concepts of transcription initiation in bacteria.

Nat Rev Genet 2020 11 14;21(11):699-714. Epub 2020 Jul 14.

Programa de Genómica Computacional, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Morelos, Cuernavaca, México.

View Article and Find Full Text PDF
November 2020

Epigenetic competition reveals density-dependent regulation and target site plasticity of phosphorothioate epigenetics in bacteria.

Proc Natl Acad Sci U S A 2020 06 9;117(25):14322-14330. Epub 2020 Jun 9.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139;

View Article and Find Full Text PDF
June 2020

A Förster Resonance Energy Transfer-Based Ratiometric Sensor with the Allosteric Transcription Factor TetR.

Small 2020 04 6;16(17):e1907522. Epub 2020 Apr 6.

Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.

View Article and Find Full Text PDF
April 2020

Comprehensive Definition of the SigH Regulon of Mycobacterium tuberculosis Reveals Transcriptional Control of Diverse Stress Responses.

PLoS One 2016 22;11(3):e0152145. Epub 2016 Mar 22.

Division of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, United States of America.

View Article and Find Full Text PDF
August 2016

Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis.

PLoS One 2016 28;11(1):e0147651. Epub 2016 Jan 28.

Technical University of Denmark, Novo Nordisk Foundation Center for Biosustainability, Hørsholm, Denmark.

View Article and Find Full Text PDF
July 2016

Metabolic modeling predicts metabolite changes in Mycobacterium tuberculosis.

BMC Syst Biol 2015 Sep 16;9:57. Epub 2015 Sep 16.

Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.

View Article and Find Full Text PDF
September 2015

Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon.

Nucleic Acids Res 2016 Jan 10;44(1):134-51. Epub 2015 Sep 10.

Department of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Albany, NY 12201, USA Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, NY 12201-2002, USA

View Article and Find Full Text PDF
January 2016