Publications by authors named "James G Krueger"

100Publications

Mild atopic dermatitis lacks systemic inflammation, and shows reduced non-lesional skin abnormalities.

J Allergy Clin Immunol 2020 Oct 1. Epub 2020 Oct 1.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.08.041DOI Listing
October 2020

Secukinumab Lowers Expression of ACE2 in Affected Skin of Patients With Psoriasis.

J Allergy Clin Immunol 2020 Sep 28. Epub 2020 Sep 28.

Oregon Medical Research Center, Portland, OR.

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http://dx.doi.org/10.1016/j.jaci.2020.09.021DOI Listing
September 2020

Tape-strips provide a minimally invasive approach to track therapeutic response to topical corticosteroids in atopic dermatitis patients.

J Allergy Clin Immunol Pract 2020 Sep 2. Epub 2020 Sep 2.

Department of Dermatology, and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.08.037DOI Listing
September 2020

SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age.

Allergy 2020 Jul 29. Epub 2020 Jul 29.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/all.14522DOI Listing
July 2020

A Preliminary F-FDG-PET/MRI Study Shows Increased Vascular Inflammation in Moderate-to-Severe Atopic Dermatitis.

J Allergy Clin Immunol Pract 2020 Jul 25. Epub 2020 Jul 25.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY; The Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY; Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.07.018DOI Listing
July 2020

Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis.

J Allergy Clin Immunol 2020 Jul 9. Epub 2020 Jul 9.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.05.048DOI Listing
July 2020

Improving evaluation of drugs in atopic dermatitis by combining clinical and molecular measures.

J Allergy Clin Immunol Pract 2020 Jul 20. Epub 2020 Jul 20.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.07.015DOI Listing
July 2020

Tape strips from early-onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin.

Allergy 2020 Jul 8. Epub 2020 Jul 8.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/all.14490DOI Listing
July 2020

A systematic review and critical appraisal of metagenomic and culture studies in hidradenitis suppurativa.

Exp Dermatol 2020 Jul 2. Epub 2020 Jul 2.

Laboratory of Investigative Dermatology, Rockefeller University, New York, New York.

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http://dx.doi.org/10.1111/exd.14141DOI Listing
July 2020

The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: An open-label cohort study.

J Am Acad Dermatol 2020 Nov 13;83(5):1341-1348. Epub 2020 May 13.

Laboratory of Investigative Dermatology, The Rockefeller University, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572493PMC
November 2020

Cross-sectional study of blood biomarkers of patients with moderate to severe alopecia areata reveals systemic immune and cardiovascular biomarker dysregulation.

J Am Acad Dermatol 2020 May 4. Epub 2020 May 4.

Department of Dermatology and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.04.138DOI Listing
May 2020

Beyond antibodies: B cells in Hidradenitis Suppurativa: Bystanders, contributors or therapeutic targets?

Exp Dermatol 2020 05 17;29(5):509-515. Epub 2020 Mar 17.

Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.

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http://dx.doi.org/10.1111/exd.14092DOI Listing
May 2020

Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.

Arterioscler Thromb Vasc Biol 2020 05 5;40(5):1340-1351. Epub 2020 Mar 5.

From the Department of Medicine, Center for the Prevention of Cardiovascular Disease (M.S.G., E.A.F., J.S.B.), New York University School of Medicine.

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http://dx.doi.org/10.1161/ATVBAHA.119.314008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180109PMC
May 2020

The aging skin microenvironment dictates stem cell behavior.

Proc Natl Acad Sci U S A 2020 03 24;117(10):5339-5350. Epub 2020 Feb 24.

Robin Neustein Laboratory of Mammalian Development and Cell Biology, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1901720117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071859PMC
March 2020

Comparing cutaneous molecular improvement with different treatments in atopic dermatitis patients.

J Allergy Clin Immunol 2020 Apr 16;145(4):1285-1288. Epub 2020 Jan 16.

Department of Dermatology and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.01.005DOI Listing
April 2020

Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis.

J Allergy Clin Immunol 2020 Mar 27;145(3):922-932. Epub 2019 Dec 27.

The Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.10.041DOI Listing
March 2020

Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept.

J Invest Dermatol 2020 May 6;140(5):1026-1034. Epub 2019 Nov 6.

Department of Population Health Science & Policy, The Icahn School of Medicine at Mount Sinai, New York; Laboratory for Investigative Dermatology, The Rockefeller University, New York; Department of Genetics and Genomics, The Icahn School of Medicine at Mount Sinai, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.09.023DOI Listing
May 2020

The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature.

J Am Acad Dermatol 2020 Mar 25;82(3):690-699. Epub 2019 Oct 25.

Department of Dermatology and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.10.039DOI Listing
March 2020

Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood.

J Allergy Clin Immunol 2020 01 15;145(1):215-228. Epub 2019 Oct 15.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957229PMC
January 2020

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis.

Ann Allergy Asthma Immunol 2020 01 14;124(1):70-78. Epub 2019 Oct 14.

Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2019.10.013DOI Listing
January 2020

Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.

J Allergy Clin Immunol 2019 10 1;144(4):1036-1049. Epub 2019 Aug 1.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.06.019DOI Listing
October 2019

Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis.

J Allergy Clin Immunol 2019 10 26;144(4):1011-1024. Epub 2019 Jul 26.

Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.07.013DOI Listing
October 2019

A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa.

F1000Res 2018 11;7:1923. Epub 2018 Dec 11.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY, 10065, USA.

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http://dx.doi.org/10.12688/f1000research.17268.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593329PMC
November 2019

Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa.

Exp Dermatol 2019 08 3;28(8):886-891. Epub 2019 Jul 3.

Laboratory of Investigative Dermatology, Rockefeller University, New York, New York.

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http://dx.doi.org/10.1111/exd.13978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663622PMC
August 2019

Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals.

J Invest Dermatol 2019 10 3;139(10):2228-2232.e10. Epub 2019 May 3.

Department of Dermatology and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.04.008DOI Listing
October 2019

The skin as an immune organ: Tolerance versus effector responses and applications to food allergy and hypersensitivity reactions.

J Allergy Clin Immunol 2019 08 5;144(2):362-374. Epub 2019 Apr 5.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY.

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http://dx.doi.org/10.1016/j.jaci.2019.03.021DOI Listing
August 2019

Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms.

Ther Adv Chronic Dis 2019 1;10:2040622319830646. Epub 2019 Mar 1.

Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.

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http://dx.doi.org/10.1177/2040622319830646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399757PMC
March 2019

A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa.

F1000Res 2018 13;7:1930. Epub 2018 Dec 13.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY, 10065, USA.

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http://dx.doi.org/10.12688/f1000research.17267.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392156PMC
September 2019

Inflammasome Signaling and Impaired Vascular Health in Psoriasis.

Arterioscler Thromb Vasc Biol 2019 04;39(4):787-798

From the Center for the Prevention of Cardiovascular Disease, Department of Medicine (M.S.G., E.A.F., J.S.B.), New York University School of Medicine, New York.

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http://dx.doi.org/10.1161/ATVBAHA.118.312246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436998PMC
April 2019

Modulation of inflammatory gene transcripts in psoriasis vulgaris: Differences between ustekinumab and etanercept.

J Allergy Clin Immunol 2019 05 29;143(5):1965-1969. Epub 2019 Jan 29.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.017DOI Listing
May 2019

Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.

J Allergy Clin Immunol 2019 07 24;144(1):144-156. Epub 2019 Jan 24.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.015DOI Listing
July 2019

Atopic dermatitis endotypes and implications for targeted therapeutics.

J Allergy Clin Immunol 2019 01;143(1):1-11

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.10.032DOI Listing
January 2019

Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases.

J Allergy Clin Immunol 2019 06 18;143(6):2095-2107. Epub 2018 Dec 18.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.11.031DOI Listing
June 2019

Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients.

Ann Allergy Asthma Immunol 2019 03 1;122(3):318-330.e3. Epub 2018 Dec 1.

The Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York; Department of Dermatology, the Laboratory for Inflammatory Skin Diseases, and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2018.11.025DOI Listing
March 2019

Atopic dermatitis in African American patients is T2/T22-skewed with T1/T17 attenuation.

Ann Allergy Asthma Immunol 2019 01 14;122(1):99-110.e6. Epub 2018 Sep 14.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2018.08.024DOI Listing
January 2019

Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis.

J Immunol 2018 09;201(6):1605-1613

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY 10065; and

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1800013
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http://dx.doi.org/10.4049/jimmunol.1800013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129988PMC
September 2018

An integrated model of alopecia areata biomarkers highlights both T1 and T2 upregulation.

J Allergy Clin Immunol 2018 11 5;142(5):1631-1634.e13. Epub 2018 Jul 5.

Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.06.029DOI Listing
November 2018

Atopic dermatitis in Chinese patients shows T2/T17 skewing with psoriasiform features.

J Allergy Clin Immunol 2018 09 28;142(3):1013-1017. Epub 2018 Jun 28.

Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.06.016DOI Listing
September 2018

IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis.

J Invest Dermatol 2018 07;138(7):1467-1469

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1016/j.jid.2018.02.037DOI Listing
July 2018

Synergistic cytokine effects as apremilast response predictors in patients with psoriasis.

J Allergy Clin Immunol 2018 09 21;142(3):1010-1013.e6. Epub 2018 Jun 21.

Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.05.039DOI Listing
September 2018

Proportion of CD4CD49bLAG-3 Type 1 Regulatory T Cells in the Blood of Psoriasis Patients Inversely Correlates with Psoriasis Area and Severity Index.

J Invest Dermatol 2018 12 8;138(12):2669-2672. Epub 2018 Jun 8.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X183204
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http://dx.doi.org/10.1016/j.jid.2018.05.021DOI Listing
December 2018

Ichthyosis molecular fingerprinting shows profound T17 skewing and a unique barrier genomic signature.

J Allergy Clin Immunol 2019 02 24;143(2):604-618. Epub 2018 May 24.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195861PMC
February 2019

Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment.

Ther Adv Chronic Dis 2018 May 19;9(5):111-119. Epub 2018 Mar 19.

The Milstein Research Program, Laboratory Head, Investigative Dermatology, The Rockefeller University, 1230 York Avenue, Box 178, New York, NY 10065, USA.

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http://dx.doi.org/10.1177/2040622318759282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956648PMC
May 2018

Early-onset pediatric atopic dermatitis is characterized by T2/T17/T22-centered inflammation and lipid alterations.

J Allergy Clin Immunol 2018 06 3;141(6):2094-2106. Epub 2018 May 3.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183039
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http://dx.doi.org/10.1016/j.jaci.2018.02.040DOI Listing
June 2018

The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood.

J Invest Dermatol 2018 10 14;138(10):2157-2167. Epub 2018 Apr 14.

Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.03.1523DOI Listing
October 2018

Serum from Asian patients with atopic dermatitis is characterized by T2/T22 activation, which is highly correlated with nonlesional skin measures.

J Allergy Clin Immunol 2018 07 11;142(1):324-328.e11. Epub 2018 Apr 11.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.02.047DOI Listing
July 2018

Interleukin-17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities.

Exp Dermatol 2018 02 29;27(2):115-123. Epub 2017 Dec 29.

Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY, USA.

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http://doi.wiley.com/10.1111/exd.13467
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http://dx.doi.org/10.1111/exd.13467DOI Listing
February 2018

Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones.

J Clin Invest 2017 Nov 25;127(11):4031-4041. Epub 2017 Sep 25.

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI93396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663366PMC
November 2017

Psoriasis pathogenesis and the development of novel targeted immune therapies.

J Allergy Clin Immunol 2017 Sep;140(3):645-653

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600287PMC
September 2017

Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?

Curr Opin Immunol 2017 Oct 1;48:68-73. Epub 2017 Sep 1.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA.

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http://dx.doi.org/10.1016/j.coi.2017.08.008DOI Listing
October 2017

Line scanning, stage scanning confocal microscope (LSSSCM).

Biomed Opt Express 2017 Aug 24;8(8):3807-3815. Epub 2017 Jul 24.

Ronald O. Pearleman Department of Dermatology, New York University, 240 E. 38th St., New York, NY 10016, USA.

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https://www.osapublishing.org/abstract.cfm?URI=boe-8-8-3807
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http://dx.doi.org/10.1364/BOE.8.003807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560842PMC
August 2017

Response to Hjuler et al.

J Invest Dermatol 2017 10 23;137(10):2237-2238. Epub 2017 Jun 23.

Montreal Heart Institute Research Center, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.jid.2017.05.027DOI Listing
October 2017

Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march.

J Allergy Clin Immunol 2017 Jun;139(6):1723-1734

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.04.004DOI Listing
June 2017

The management of moderate-to-severe chronic plaque psoriasis.

G Ital Dermatol Venereol 2017 Oct 23;152(5):447-457. Epub 2017 May 23.

Department of Dermatology, University of Pisa, Pisa, Italy -

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http://dx.doi.org/10.23736/S0392-0488.17.05681-4DOI Listing
October 2017

Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting.

J Rheumatol 2017 05;44(5):679-683

From Clinical Investigation, The Rockefeller University, New York; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Guy's and St. Thomas' UK National Health Service (NHS) Foundation Trust; King's College London, London, UK.

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http://dx.doi.org/10.3899/jrheum.170143DOI Listing
May 2017

Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis.

N Engl J Med 2017 04;376(16):1551-1560

From K. Papp Clinical Research and Probity Medical Research, Waterloo, ON (K.A.P.), School of Medicine, Queen's University, Kingston, ON (M.G.), and Centre for Dermatology and Probity Medical Research, Peterborough, ON (M.G.) - all in Canada; Oregon Medical Research Center, Portland (A.B.); Altman Dermatology Associates, Arlington Heights, IL (M.B.); Rockefeller University, New York (J.K.); Hôpital de l'Archet, University of Nice-Sophia Antipolis, Nice, France (J.-P.L.); Baylor Research Institute, Dallas (A.M.); Charité Universitätsmedizin Berlin, Berlin (S.P.), Boehringer Ingelheim Pharma, Biberach (B.R.B.), and Boehringer Ingelheim Pharma, Ingelheim, (S.J.P.) - all in Germany; University of Texas Health Science Center, Houston (S.T.); University of California, Los Angeles, School of Medicine, Los Angeles (H.S.); and Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (S.V., C.P., N.B., M.F., P.S.).

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http://dx.doi.org/10.1056/NEJMoa1607017DOI Listing
April 2017

Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment.

Exp Dermatol 2018 04 9;27(4):409-417. Epub 2017 May 9.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/exd.13336DOI Listing
April 2018

Expression of Programmed Cell Death Ligand in Cutaneous Squamous Cell Carcinoma and Treatment of Locally Advanced Disease With Pembrolizumab.

JAMA Dermatol 2017 Apr;153(4):299-303

Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1001/jamadermatol.2016.5118DOI Listing
April 2017

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism.

Nature 2017 03 20;543(7644):252-256. Epub 2017 Feb 20.

Department of Dermatology and Harvard Skin Disease Research Center, Brigham and Women's Hospital, Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nature21379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509051PMC
March 2017

MAGEA3 Expression in Cutaneous Squamous Cell Carcinoma Is Associated with Advanced Tumor Stage and Poor Prognosis.

J Invest Dermatol 2017 03 5;137(3):775-778. Epub 2016 Nov 5.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.036DOI Listing
March 2017

An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease.

J Invest Dermatol 2017 03 4;137(3):603-613. Epub 2016 Nov 4.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA; Department of Immunology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.09.037DOI Listing
March 2017

Digital imaging biomarkers feed machine learning for melanoma screening.

Exp Dermatol 2017 07 19;26(7):615-618. Epub 2016 Dec 19.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA.

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http://dx.doi.org/10.1111/exd.13250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516237PMC
July 2017

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.

J Invest Dermatol 2016 11 13;136(11):2173-2182. Epub 2016 May 13.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.04.032DOI Listing
November 2016

Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.

J Dermatol Sci 2017 Jan 29;85(1):20-26. Epub 2016 Sep 29.

Laboratory of Investigative Dermatology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065 USA.

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http://dx.doi.org/10.1016/j.jdermsci.2016.09.019DOI Listing
January 2017

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.

J Allergy Clin Immunol 2017 02 1;139(2):562-571. Epub 2016 Oct 1.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.08.029DOI Listing
February 2017