James F Meschia

James F Meschia

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James F Meschia

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Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

CNS small vessel disease: A clinical review.

Neurology 2019 Jun 29;92(24):1146-1156. Epub 2019 May 29.

From the Department of Neurology (R.J.C., M.B., B.H.E., J.F.M.), Department of Laboratory Medicine and Pathology (D.W.D.), Department of Neuroscience (D.W.D.), and Department of Radiology (E.H.M.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000007654DOI Listing
June 2019

Mesenchymal stem cells for hemorrhagic stroke: status of preclinical and clinical research.

NPJ Regen Med 2019 13;4:10. Epub 2019 May 13.

3Department of Neurology, Mayo Clinic Florida, Jacksonville, FL USA.

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http://dx.doi.org/10.1038/s41536-019-0073-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513857PMC
May 2019

Pharmacotherapy for Patients With Atrial Fibrillation and Cerebral Microbleeds.

J Stroke Cerebrovasc Dis 2019 May 15. Epub 2019 May 15.

Department of Neurology, Mayo Clinic Florida, Jacksonville, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.04.027DOI Listing
May 2019

Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis.

Neurology 2019 Apr 5;92(18):e2150-e2164. Epub 2019 Apr 5.

From the Wessex Neurological Centre (B.G., D.O.B., I.G.), University Hospital Southampton NHS Foundation Trust, UK; School of Nursing (D.R., S.A.) and Department of Biostatistics (D.R., T.E.), University of Pittsburgh, PA; Department of Neurology (E.R.B.), Duke University School of Medicine, Durham, NC; NeuroSpring (D.M.B., M.K.B.), Dover, DE; Department of Neurosurgery (S.L.B.), University of Texas Health Science Center at Houston; Department of Anesthesiology, Neurology, Psychiatry, Psychology, Pharmaceutics, and Neuroscience (S.D., J.L.L.), College of Medicine, Center for Translational Research in Neurodegenerative Disease, McKnight Brain Institute, University of Florida, Gainesville; Brain Injury Research Group (J.G.), Division of Cardiovascular Sciences (University of Manchester), Salford Royal NHS Foundation Trust, UK; Clinical Neurosciences, Clinical & Experimental Sciences (P.G., I.G.), Faculty of Medicine, University of Southampton, UK; Department of Neurosurgery (K.I., Y.K.), Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Neurology (J.F.M., M.A.P.), Mayo Clinic, Jacksonville, FL; and Division of Cerebrovascular Neurosurgery (R.J.T.) and Departments of Neurology, Anesthesia/Critical Care Medicine, and Neurosurgery (W.Y., P.A.N.), Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000007397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512887PMC
April 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

The Clinical Dilemma of Anticoagulation Use in Patients with Cerebral Amyloid Angiopathy and Atrial Fibrillation.

Curr Cardiol Rep 2018 09 12;20(11):106. Epub 2018 Sep 12.

From the Department of Neurology (RJC, JFM), Mayo Clinic in Florida, 4500 San Pablo Road, Jacksonville, FL, 32256, USA.

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http://dx.doi.org/10.1007/s11886-018-1052-1DOI Listing
September 2018

Destigmatizing Migraine.

Cureus 2018 May 30;10(5):e2711. Epub 2018 May 30.

Neurology, Mayo Clinic Jacksonville, Fl, Jacksonville, USA.

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http://dx.doi.org/10.7759/cureus.2711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066189PMC
May 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

Discovery of a cause of vein of Galen malformations.

Authors:
James F Meschia

Brain 2018 04;141(4):936-938

Cerebrovascular Division, Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

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http://dx.doi.org/10.1093/brain/awy066DOI Listing
April 2018

Diagnosis and Management of Acute Ischemic Stroke.

Mayo Clin Proc 2018 04;93(4):523-538

Department of Neurologic Surgery, Mayo Clinic, Jacksonville, FL. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2018.02.013DOI Listing
April 2018

Informing vs Changing the Practice of Carotid Revascularization.

Authors:
James F Meschia

JAMA Neurol 2018 Jan;75(1):20-21

Department of Neurology, Mayo Clinic, Jacksonville, Florida.

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http://dx.doi.org/10.1001/jamaneurol.2017.3298DOI Listing
January 2018

Carotid Stenting Versus Carotid Endarterectomy: What Did the Carotid Revascularization Endarterectomy Versus Stenting Trial Show and Where Do We Go From Here?

Angiology 2017 Sep 9;68(8):675-682. Epub 2016 Aug 9.

2 Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

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http://dx.doi.org/10.1177/0003319716661661DOI Listing
September 2017

Translational Stroke Research: Vision and Opportunities.

Stroke 2017 09 27;48(9):2632-2637. Epub 2017 Jul 27.

From the National Institute of Neurological Disorders and Stroke, National Institutes of Health (F.B., J.I.K., R.A.C., L.B.J., S.J., L.M.M., C.S.M., I.R., W.K.); Department of Neurology, Massachusetts General Hospital, Boston (C.A., E.H.L., L.H.S.); Oregon Health & Science University, Portland (S.A.B., M.P.S.-P.); Department of Neurology and Neurological Surgery, University of Washington, Seattle (K.B.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (J.P.B.); Department of Neurology, University of California, Los Angeles (S.T.C.); Brain Mind Research Institute, Weill Cornell Medicine, New York, NY (S.C., C.I.); Department of Neurological Sciences, University of Vermont, Burlington (M.J. C.); Brain and Mind Research Institute, University of Ottawa, Ontario (D.C.); Department of Neurology, University of California, Irvine, Orange (S.C.C.); Department of Neurological Surgery, University of California, San Francisco (A.R.F.); Stemetix, Inc, Needham, MA (S.F.); Division of Biomedical Sciences, University of California, Riverside (B.D.F.); Department of Neurology, Brown University, Providence, RI (K.L.F.); Department of Neurology, University of California, San Diego (T.M.H.); Department of Emergency Medicine, Medical University of South Carolina, Charleston (E.C.J.); Department of Neurology, University of Virginia, Charlottesville (K.C.J.); Department of Critical Care Medicine (P.M.K.) and Department of Neurology (L.R.W.), University of Pittsburgh, PA; School of Pharmacy, University of North Carolina, Chapel Hill (H.K.); Cedars-Sinai Medical Center, Los Angeles, CA (P.D.L.); University of Gothenburg, Sweden (C.M.); Department of Neurology, University of Texas Health Science Center, Houston (L.D.M., S.I.S.); Mayo Clinic, Jacksonville, FL (J.F.M.); Department of Neurology, University of Miami Miller School, FL (M.A.P.-P.); Department of Neurosurgery, Stanford University, CA (G.K.S.); Division of Fundamental Neurobiology, Krembil Research Institute, Toronto, ON (M.T.); Department of Neurology, University of Texas, Austin (S.W.); and Department of Neurosurgery and Anesthesiology, Loma Linda University, CA (J.H.Z.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599159PMC
September 2017

Factors Associated With Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial.

Stroke 2017 09 2;48(9):2511-2518. Epub 2017 Aug 2.

From the Department of Neurology, Mayo Clinic, Phoenix, AZ (B.M.D.); Department of Neurology, Mayo Clinic, Rochester, MN (R.D.B.); Department of Cardiology, Brookwood Medical Center, Birmingham, AL (G.S.R.); Department of Epidemiology, University of Alabama, Birmingham (V.J.H.); Department of Neurology, Mayo Clinic, Jacksonville, FL (E.C., K.M.B., M.E.L., T.G.B., J.F.M.); Department of Neurology, Medical University of South Carolina, Charleston (J.H.V.); Department of Neurology and Stroke Program, University of Miami Miller School of Medicine, FL (S.C.); Department of Surgery, University of Maryland, Baltimore (B.K.L.); and Department of Biostatistics, University of Alabama at Birmingham (G.H.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575963PMC
September 2017

Improving practice through neurovascular board.

Neurology 2017 07 28;89(4):316-317. Epub 2017 Jun 28.

From the Department of Neurology, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000004161DOI Listing
July 2017

Evaluation and Management of Atherosclerotic Carotid Stenosis.

Mayo Clin Proc 2017 07;92(7):1144-1157

Department of Neurology, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1016/j.mayocp.2017.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576141PMC
July 2017

Duplex velocity criteria for carotid endarterectomy.

J Vasc Surg 2017 04;65(4):938-939

Department of Vascular Surgery, University of Maryland Medical Center, Baltimore, Md.

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http://dx.doi.org/10.1016/j.jvs.2017.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393915PMC
April 2017

Alpha-1 antitrypsin dysfunction and large artery stroke.

Authors:
James F Meschia

Proc Natl Acad Sci U S A 2017 04 27;114(14):3555-3557. Epub 2017 Mar 27.

Department of Neurology, Mayo Clinic, Jacksonville, FL 32224

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http://dx.doi.org/10.1073/pnas.1702751114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389318PMC
April 2017

Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial.

Semin Vasc Surg 2017 Mar 27;30(1):2-7. Epub 2017 Apr 27.

Department of Neurology, Mayo Clinic, Griffin Building, 3(rd) Floor, 4500 San Pablo Road, Jacksonville, FL 32224. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08957967173000
Publisher Site
http://dx.doi.org/10.1053/j.semvascsurg.2017.04.004DOI Listing
March 2017

Introduction to the Symposium on Neurosciences.

Mayo Clin Proc 2017 02;92(2):182-183

Department of Neurology, Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.1016/j.mayocp.2016.12.005DOI Listing
February 2017

High-Sensitivity C-Reactive Protein and Risk of Stroke in Atrial Fibrillation (from the Reasons for Geographic and Racial Differences in Stroke Study).

Am J Cardiol 2016 Dec 14;118(12):1826-1830. Epub 2016 Sep 14.

Section on Cardiovascular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina; Epidemiological Cardiology Research Center, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2016.08.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127742PMC
December 2016

The urgent need for contemporary clinical trials in patients with asymptomatic carotid stenosis.

Neurology 2016 Nov 28;87(21):2271-2278. Epub 2016 Sep 28.

From the University of Miami Miller School of Medicine (S.C.), FL; Medical University of South Carolina (M.C.), Charleston; Mayo Clinic (R.D.B.), Rochester, MN; University of Maryland School of Medicine (B.K.L.), Baltimore; and Mayo Clinic (J.F.M.), Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000003267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123552PMC
November 2016

Screening individuals with intracranial aneurysms for abdominal aortic aneurysms is cost-effective based on estimated coprevalence.

J Vasc Surg 2016 09;64(3):811-818.e3

Department of Neurology, University of Virginia, Charlottesville, Va; Department of Public Health Sciences, University of Virginia, Charlottesville, Va.

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http://dx.doi.org/10.1016/j.jvs.2016.05.065DOI Listing
September 2016

Interventions for Extracranial Carotid Artery Stenosis: An Update.

Curr Treat Options Cardiovasc Med 2016 May;18(5):34

The Department of Neurology (JFH, JFM), Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1007/s11936-016-0455-9DOI Listing
May 2016

The Relationship Between Serum Neuron-Specific Enolase Levels and Severity of Bleeding and Functional Outcomes in Patients With Nontraumatic Subarachnoid Hemorrhage.

Neurosurgery 2016 Apr;78(4):487-91

*Department of Neurosurgery, Mayo School of Health Sciences, Mayo Clinic College of Medicine, Jacksonville, Florida; ‡Division of Biomedical Statistics and Informatics, Mayo School of Health Sciences, Mayo Clinic College of Medicine, Jacksonville, Florida; §Department of Neurology, Mayo School of Health Sciences, Mayo Clinic College of Medicine, Jacksonville, Florida; Departments of ¶Critical Care and ‖Neurology, Mayo Clinic, Jacksonville, Florida.

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https://academic.oup.com/neurosurgery/article-lookup/doi/10.
Publisher Site
http://dx.doi.org/10.1227/NEU.0000000000001140DOI Listing
April 2016

Candidate-gene analysis of white matter hyperintensities on neuroimaging.

J Neurol Neurosurg Psychiatry 2016 Mar 2;87(3):260-6. Epub 2015 Apr 2.

Institute of Cardiovascular Research, Royal Holloway University of London (ICR2UL) and Ashford & St Peters NHS Foundation Trust, London, UK Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2014-309685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789815PMC
March 2016

Stroke Symptoms as a Predictor of Future Hospitalization.

J Stroke Cerebrovasc Dis 2016 Mar 8;25(3):702-9. Epub 2016 Jan 8.

Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779679PMC
March 2016

Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis.

N Engl J Med 2016 Mar 18;374(11):1021-31. Epub 2016 Feb 18.

From the Mayo Clinic, Jacksonville, FL (T.G.B., J.F.M.); the University of Alabama at Birmingham (G.H., V.J.H.) and Cardiovascular Associates of the Southeast (G.S.R.) - both in Birmingham; Centre Hospitalier Universitaire de Québec-Université Laval, Quebec, QC (A.M.), and the University of Calgary, Calgary, AB (M.D.H.) - both in Canada; Baptist Health Lexington, KY (W.B.); the University of California, Los Angeles, Los Angeles (W.S.M.); Mercy Hospital St. Louis, St. Louis (V.A.M.); Oregon Health and Science University, Portland (W.M.C.); the University of Texas Southwestern Medical Center, Dallas (C.H.T); Novant Health Clinical Research, Winston-Salem, NC (D.H.); the Providence Sacred Heart Medical Center and Children's Hospital, Spokane, WA (P.P.L.); Rutgers New Jersey Medical School, Newark (A.J.S., R.W.H.); the University of Miami Miller School of Medicine, Miami (S.C.); the University of Maryland Medical Center, Baltimore (B.K.L.); and the Medical University of South Carolina, Charleston (J.H.V.).

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http://dx.doi.org/10.1056/NEJMoa1505215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874663PMC
March 2016

The High Risk of Low Distal Flow.

Authors:
James F Meschia

JAMA Neurol 2016 Feb;73(2):157-8

Department of Neurology, Mayo Clinic Florida, Jacksonville.

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http://dx.doi.org/10.1001/jamaneurol.2015.3885DOI Listing
February 2016

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.

Stroke 2016 Feb 5;47(2):307-16. Epub 2016 Jan 5.

From the Veterans Affairs Maryland Health Care System, Baltimore, MD (Y.-C.C., S.J.K., J.W.C., B.D.M.); University of Maryland School of Medicine, Baltimore (Y.-C.C., H.X., S.J.K., J.W.C., J.R.O., B.D.M.); The University of Gothenburg, Gothenburg, Sweden (T.M.S., C.J.); University of Rostock, Rostock, Germany (A.-K.G., A. Rolfs); University of Nottingham Malaysia Campus, Selangor Darul Ehsa, Malaysia (W.K.H.); University of Cambridge, Cambridge, UK (M.T., J.D., S.B., H.S.M., S.D., D.S.); Institut Pasteur de Lille, F-59000 Lille, France (P.A.); University of Newcastle, Australia (E.G.H.); Ludwig-Maximilians-Universität, Munich, Germany (R.M., K.S., M.D.); Wellcome Trust Sanger Institute, Cambridge, UK (J.D.); Center for Non-Communicable Diseases, Karachi, Pakistan (A. Rasheed, D.S.); University of Pennsylvania (W.Z., D.S.); Basel University Hospital, Switzerland (S.E.); Heidelberg University Hospital, Germany (C.G.-G.); Centre d'Étude du Polymorphisme Humain, Paris, France (Y.K.); RIKEN Center for Integrative Medical Sciences, Yokohama, Japan (Y.K.); National Genotyping Center, Evry, France (M.L.); Genome Quebec, McGill University, Montreal, Canada (M.L.); Lille University Hospital, France (D.L., S.D.); KU Leuven - University of Leuven, Leuven, Belgium (V.T.); Vesalius Research Center, VIB, Leuven, Belgium (V.T.); University Hospitals Leuven, Leuven, Belgium (V.T.); Helsinki University Central Hospital, Helsinki, Finland (T.M.M., T.T.); Università degli Studi di Brescia, Brescia, Italy (A. Pezzini); Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (E.A.P., G.B.B.); University of Lund, Sweden (B.N.); University of Oxford, John Radcliffe Hospital (P.M.R.); University of Edinburgh, Edinburgh, UK (C.S.); Jagiellonian University Medical College, Krakow, Poland (A.S.); Lund University, Lund, Sweden (A.L.); Skåne University Hospital, Lund, Sweden (A.L.); University of Glasgow, Glasgow, UK (M.R.W.); University of Adelaide, Australia (J.J.); Mount Sinai Hos

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February 2016

Pacemakers as Atrial Fibrillation Detectors: Finding Racial Differences and Opportunities for Preventing Stroke.

Authors:
James F Meschia

J Am Heart Assoc 2016 02 12;5(2). Epub 2016 Feb 12.

Department of Neurology, Mayo Clinic, Jacksonville, FL

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February 2016

Heart rate and ischemic stroke: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.

Int J Stroke 2015 Dec 26;10(8):1229-35. Epub 2015 Aug 26.

Department of Medicine, Section on Cardiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938895PMC
December 2015

Time From Symptoms to Carotid Endarterectomy or Stenting and Perioperative Risk.

Stroke 2015 Dec 22;46(12):3540-2. Epub 2015 Oct 22.

From the Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M., T.G.B.); Department of Neurosurgery, University at Buffalo-SUNY, NY (L.N.H.); Minneapolis Clinic of Neurology, Golden Valley (I.A.); Department of Neurology, University of Pittsburgh School of Medicine, PA (L.R.W.); Department of Neurology, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada (G.S.); Department of Neurology, University of Texas Medical School, Houston (N.R.G.); Department of Neurology, Medical University of South Carolina, Charleston (J.H.V.); and Department of Biostatistics, Ryals School of Public Health, University of Alabama at Birmingham (G.H.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765730PMC
December 2015

Stroke: advances in medical therapy and acute stroke intervention.

Curr Cardiol Rep 2015 Oct;17(10):79

Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA,

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October 2015

Mediators of the Age Effect in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST).

Stroke 2015 Oct 8;46(10):2868-73. Epub 2015 Sep 8.

From the Department of Neurology, Medical University of South Carolina, Charleston (J.H.V.); Department of Biostatistics, University of Alabama at Birmingham (G.H.); Cardiovascular Associates of the Southeast, Birmingham, AL (G.R.); Division of Neuroradiology, Department of Medical Imaging, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada (R.F.); Department of Radiology, Novant Health Forsyth Medical Center, Winston-Salem, NC (D.H.); Mercy Clinic Neurology, Mercy Hospital, St. Louis, MO (W.L.); Department of Neurology, Mayo Clinic, Jacksonville, FL (M.L., J.F.M., T.G.B.); and Department of Surgery, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark (A.S., T.G.B.).

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October 2015

Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.

Stroke 2015 Aug 18;46(8):2063-8. Epub 2015 Jun 18.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA (C.L.C., C.K., A.R.); Center for Health Disparities, East Carolina University, Greenville, NC (K.L.K.); Baltimore Veterans Administration Medical Center, MD (Y.-C.C., S.J.K.); University of Maryland School of Medicine, Baltimore (Y.-C.C., S.J.K., B.D.M.); Mayo Clinic Florida, Jacksonville, FL (J.F.M.); Public Health Sciences, University of Virginia, Charlottesville (W.-M.C., S.S.R., M.M.S., B.B.W.); National Institute of Aging, NIH, Bethesda, MD (M.N., S.T., A.B.Z., M.K.E.); University of Washington, Seattle (J.C.B., W.T.L., B.M.P., A.R.); Wake Forest University, Winston-Salem, NC (C.D.L., Y.L.); Division of Cerebrovascular Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.G.); Department of Neurology, University of Mississippi Medical Center, Jackson (T.H.M.); Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson (E.S.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (D.W.); Department of Psychiatry, University of California, San Francisco (K.Y.); Institute for Stroke and Dementia Research, Munich Cluster for Systems Neurology (Synergy), Klinikum der Universität München, Ludwig-Maximilians-Universität; Munich, Germany (M.D., R.M.); Group Health Research Unit, Group Health Cooperative, Seattle, WA (B.M.P.); and Center for Human Genetics, University of Texas, Houston (M.F.).

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August 2015

Rare Coding Variation and Risk of Intracerebral Hemorrhage.

Stroke 2015 Aug 25;46(8):2299-301. Epub 2015 Jun 25.

From the Center for Human Genetic Research (F.R., G.J.F., C.D.A., W.J.D., T.W.K.B., M.R.R., J.R.), Division of Neurocritical Care and Emergency Neurology, Department of Neurology (F.R., G.J.F., C.D.A., W.J.D., T.W.K.B., M.R.R., J.R.), J. Philip Kistler Stroke Research Center (F.R., G.J.F., C.D.A., W.J.D., T.W.K.B., A.M.A., M.R.R., K.S., A.V., S.M.G., J.R.), and Department of Emergency Medicine (J.N.G.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (F.R., G.J.F., C.D.A., W.J.D., T.W.K.B., M.R.R., J.R.); Department of Biostatistical Sciences, Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, NC (D.M., W.M.B., C.D.L.); Quinnipiac University, Frank H. Netter MD School of Medicine, Hamden, CT (W.J.D.); Department of Environmental Health (G.S., R.D.) and Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Department of Neurology, Harborview Medical Center, University of Washington, Seattle (D.L.T.); Department of Neurology, University of Florida College of Medicine, Jacksonville (S.L.S.); Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (M.S.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Department of Neurology, University of Michigan Health System, Ann Arbor (D.L.B.); and Departments of Neurology and Public Health Sciences, University of Virginia Health System, Charlottesville (B.B.W.).

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August 2015

Temporal Changes in Periprocedural Events in the Carotid Revascularization Endarterectomy Versus Stenting Trial.

Stroke 2015 Aug 14;46(8):2183-9. Epub 2015 Jul 14.

From the Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), School of Public Health, and Department of Surgery, School of Medicine (M.R.H.), University of Alabama at Birmingham; Department of Neurosurgery, University of Buffalo, NY (L.N.H.); Division of Vascular and Endovascular Surgery, University of California, Los Angeles (W.S.M.); Miami Cardiac and Vascular Institute, Baptist Health South Florida (B.T.K.); Department of Cardiology, Clara Maass Medical Center, Baptist Health System, Belleville, NJ (E.C.); Department of Cardiology, Beth Israel Medical Center, Newark, NJ (E.C.); Department of Radiology, Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada (W.F.M.); Department of Radiology, MetroHealth Medical Center, Cleveland, OH (R.D.F.); Department of Surgery, Kaiser Permanente, San Diego, CA (R.J.H.); Department of Cardiology, Washington Adventist Hospital, Takoma Park, MD (F.A.S.); Department of Neurosciences, Medical University of South Carolina, MUSC Stroke Center, Charleston (J.H.V.); Department of Vascular Surgery, University of Maryland School of Medicine, Baltimore (B.K.L.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M., T.G.B.); and Department of Surgery, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark (T.G.B.).

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August 2015

Is blood pressure control for stroke prevention the correct goal? The lost opportunity of preventing hypertension.

Stroke 2015 Jun 7;46(6):1595-600. Epub 2015 May 7.

From the Departments of Biostatistics (G.H.) and Epidemiology (V.J.H., P.M.), UAB School of Public Health, Birmingham, AL; Department of Hypertension, Medical University of Lodz, Lodz, Poland (M.B.); Department of Medicine, University of Vermont, Burlington (M.C.); Office of the Dean, Colorado School of Public Health, Aurora, CO (D.C.G.); Department of Neurosciences, Medical University of South Carolina, Charleston (D.T.L.); Bureau of Health Promotion and Chronic Disease, Alabama Department of Public Health, Montgomery (J.M.V., M.R.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Department of Medicine, UAB School of Medicine, Birmingham, AL (S.O.); and Department of Medicine, Morehouse School of Medicine, Atlanta, GA (H.A.T.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924927PMC
June 2015

Genetic overlap between diagnostic subtypes of ischemic stroke.

Stroke 2015 Mar 22;46(3):615-9. Epub 2015 Jan 22.

From the School of Medicine and Public Health (E.G.H., J.A.), School of Biomedical Sciences and Pharmacy (L.F.L., R.J.S.), and School of Nursing and Midwifery (J.M.M.), University of Newcastle, Australia; Clinical Research Design, IT and Statistical Support Unit, Public Health Research Program, Hunter Medical Research Institute, Newcastle, Australia (E.G.H., C.O., J.A.); Department of Clinical Neurosciences, University of Cambridge, UK (M.T., S.B., H.S.M.); Institute for Stroke and Dementia Research, Klinikum der Universität Mün-chen, Ludwig-Maximilians-Universität, Munich, Germany (R.M., M.D.); Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA (G.F., J.R.); Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (G.F., J.R.); Clinical Trial Service Unit and Epidemiological Studies Unit (J.C.H., R.C.) and Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience (P.M.R.), University of Oxford, UK; Department of Medicine (Y.-C.C., B.D.M.) and Department of Neurology (J.W.C., S.J.K.), University of Maryland School of Medicine, Baltimore, MD; Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College, London, UK (I.C.); Cardiovascular Health Research Unit, Department of Medicine (J.C.B., B.M.P., K.L.W.) and Department of Epidemiology (B.M.P.), University of Washington, Seattle, WA; Institute of Molecular Medicine and Human Genetics Center, the University of Texas Health Science Center at Houston, TX (E.B., M.F.); Department of Cerebrovascular Disease, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (G.B.B., E.A.P.); Department of Neurology, Veterans Affairs Medical Center, Baltimore, MD (J.W.C., S.J.K.); Department of Neurology, Rhode Island Hospital, Providence, RI (K.L.F.); Departments of Epidemiology, Neurology, and Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands (M.A.I.); School of Medicine, University of Adelaide, Australia (J.J.); H

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March 2015

Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke.

Stroke 2015 Feb 30;46(2):348-53. Epub 2014 Dec 30.

From the Neuroscience Research Centre, Cardiovascular & Cell Sciences, St. George's University of London, London, United Kingdom (P.A.-S., S.L.); Department of Neurology, Center for Human Genetic Research, Massachusetts General Hospital, Boston (W.D., C.R.Z., L.C., G.J.F., F.R., K.F., A.K., J.R., N.S.R.); Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (M.T., S.B., H.S.M.); Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (F.R., J.R.); Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, Oxford, United Kingdom (P.M.R.); Division of Clinical Neurosciences, Neuroimaging Sciences, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy (G.B.B.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Centre for Clinical Epidemiology and Biostatistics, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (C.L.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University Munich, Munich, Germany (M.D.); and Munich Cluster for Systems Neurology (SyNergy), Center for Stroke and Dementia Research, Munich, Germany (M.D.).

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February 2015

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection.

Nat Genet 2015 Jan 24;47(1):78-83. Epub 2014 Nov 24.

1] INSERM U744, Lille, France. [2] Institut Pasteur de Lille, Lille, France. [3] Université Lille Nord de France, Lille, France.

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January 2015

Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.

Stroke 2014 Dec 6;45(12):3589-96. Epub 2014 Nov 6.

From the Department of Radiology, AA Martinos Center for Biomedical Imaging (H.A., E.M.A., T.B.), Stroke Service, Department of Neurology (H.A., J.R.), and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (G.A., H.D., A.L., O.M., B.N.); Department of Neurology, Mayo Clinic Rochester, MN (R.D.B.); Department of Neurology (S.N.C., B.B.W.), Center for Public Health Genomics (S.S.R.), and Department of Public Health Sciences (B.B.W.), University of Virginia, Charlottesville; Department of Neurology (J.W.C., S.J.K.) and Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine (P.F.M.), University of Maryland School of Medicine, Baltimore; Institute for Stroke and Dementia Research (ISD), Klinikum der Universität München, Ludwig-Maximilians-University, München, Germany (M.D., M.L.); Department of Clinical Science, Lund University, Malmö, Sweden (G.E., B.N.); Department of Neurology, Neurovascular Research Group, IMIM-Hospital del Mar, Universitat Autonoma de Barcelona/DCEXS-Universitat Pompeu Fabra, Spain (E.G.-S., J.J.-C., J.R.); Neuroscience Institute, Saint Francis Medical Center, Trenton, NJ (R.P.G., L.R.P.); National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (K.G.); Institute of Biomedicine (C.J., A.P.) and Institute of Neuroscience and Physiology (K.J.), Sahlgrenska Academy at University of Gothenburg, Sweden; Department of Neurology, University of Miami Miller School of Medicine, FL (M.K., T.R., R.L.S.); Department of Neurology, University of Cincinnati College of Medicine, OH (B.K., D.O.K.); Department of Neurology, Stern Stroke Center, Albert Einstein College of Medicine, Bronx, NY (D.L.L.); Department of Neuroscience and Sensory Organs, Policlinico Hospital Foundation IRCCS Cà Granda, Milan, Italy (S.L.); Department of Neurology, Washington U

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December 2014

Picking the good apples: statistics versus good judgment in choosing stent operators for a multicenter clinical trial.

Stroke 2014 Nov 11;45(11):3325-9. Epub 2014 Sep 11.

From the Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham, School of Public Health; Department of Neurology, Medical University of South Carolina, Charleston (J.H.V.); and Department of Neurology, Mayo Clinic Jacksonville, FL (J.F.M., T.G.B.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332554PMC
November 2014

Mechanism of mesenchymal stem cell-induced neuron recovery and anti-inflammation.

Cytotherapy 2014 Oct 11;16(10):1336-44. Epub 2014 Jun 11.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida, USA. Electronic address:

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October 2014

APOE ε variants increase risk of warfarin-related intracerebral hemorrhage.

Neurology 2014 Sep 22;83(13):1139-46. Epub 2014 Aug 22.

From the Center for Human Genetic Research (G.J.F., F.R., H.B.B., T.W.K.B., W.J.D., V.V., M.R.R., L.P.C., A.M.A., K.S., A.V., S.M.G., A.B., J.R., C.D.A.), J. Philip Kistler Stroke Research Center (G.J.F., F.R., H.B.B., T.W.K.B., W.J.D., V.V., M.R.R., A.B., J.R., C.D.A.), Division of Neurocritical Care and Emergency Neurology, Department of Neurology (G.J.F., F.R., H.B.B., T.W.K.B., W.J.D., M.R.R., A.B., J.R., C.D.A.), and Department of Emergency Medicine (J.N.G.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics (G.J.F., F.R., H.B.B., T.W.K.B., W.J.D., M.R.R., A.B., J.R., C.D.A.), Broad Institute, Cambridge, MA; Department of Epidemiology (G.J.F., P.K.), Harvard School of Public Health, Boston; Department of Neurology (M.S.), Beth Israel Deaconess Medical Center, Boston, MA; Department of Neurology (J.F.M.), Mayo Clinic, Jacksonville, FL; Stroke Program (D.L.B.), Department of Neurology, University of Michigan Health System, Ann Arbor; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia Health System, Charlottesville; Department of Neurology (S.L.S.), University of Florida College of Medicine, Jacksonville; Stroke Center (D.L.T.), Harborview Medical Center, University of Washington, Seattle; and University of Cincinnati College of Medicine (M.L.F., S.R.M., R.D., D.W.), OH.

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September 2014

Effect of genetic variants associated with plasma homocysteine levels on stroke risk.

Stroke 2014 Jul 20;45(7):1920-4. Epub 2014 May 20.

From the Department of Medicine, Imperial College Cerebrovascular Research Unit, Imperial College London, London, United Kingdom (I.C., N.H., P.E.R., P.S.); Institute for Stroke and Dementia Research, Medical Centre, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany (R.M., M.D.); Center for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia (E.G.H.); Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom (K.R.A.); Department of Pathology, McMaster University, Hamilton, Ontario, Canada (G.P.); Departments of Epidemiology, Medicine, and Health Services, University of Washington, Seattle (B.M.P.); Group Health Research Institute, Group Health, Seattle, WA (B.M.P.); University of Texas Health Science Center at Houston (M.F.); Departments of Epidemiology, Neurology, and Radiology (M.A.I.) and Internal Medicine (J.B.J.v.M., A.G.U.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (H.S.M.); Department of Neurology (J.R.) and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (J.R.); Veterans Affairs Medical Center, Baltimore, MD (B.D.M., S.J.K.); Departments of Medicine (B.D.M., S.J.K.) and Neurology (S.J.K.), University of Maryland School of Medicine, Baltimore; Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Departments of Neurology (B.B.W.) and Public Health Science (B.B.W.), University of Virginia, Charlottesville; and Munich Cluster for Systems Neurology, Munich, Germany (M.D.).

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July 2014

Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.

Am J Hum Genet 2014 Apr 20;94(4):511-21. Epub 2014 Mar 20.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; The J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02141, USA. Electronic address:

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April 2014

Genetic stroke syndromes.

Continuum (Minneap Minn) 2014 Apr;20(2 Cerebrovascular Disease):399-411

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April 2014

Frequency of APOE, MTHFR and ACE polymorphisms in the Zambian population.

BMC Res Notes 2014 Mar 28;7:194. Epub 2014 Mar 28.

Department of Internal Medicine, University of Zambia, P,O,Box 51237, Lusaka, Zambia.

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March 2014

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.

Stroke 2014 Feb 16;45(2):394-402. Epub 2014 Jan 16.

From the Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany (R.M., M.D.); Stroke and Dementia Research Centre, St George's University of London, London, United Kingdom (S.B., H.S.M.); Laboratory of Neurogenetics (M.A.N.) and Laboratory of Epidemiology and Population Sciences (L.J.L.), National Institute on Aging, National Institutes of Health, Bethesda, MD; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health (E.G.H.) and Center for Translational Neuroscience and Mental Health Research (C.L.), University of Newcastle, Callaghan, NSW, Australia; Center for Bioinformatics, Biomarker Discovery and Information-Based Medicine, Hunter Medical Research Institute, New Lambton, NSW, Australia (E.G.H.); Department of Neurology, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA (W.J.D., J.R.); Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (Y.-C.C., B.D.M.); Department of Veterans Affairs and Veterans Affairs Medical Center, Baltimore Geriatric Research, Education, and Clinical Center (GRECC), Baltimore, MD (Y.-C.C., B.D.M.); Department of Epidemiology (C.A.I.-V., B.F.J.V., M.A.I., C.M.v.D.), Department of Neurology (C.A.I.-V., M.A.I.), and Department of Radiology (B.F.J.V., M.A.I.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; Cardiovascular Health Research Unit (J.C.B., B.M.P.), Department of Medicine (J.C.B., B.M.P.), Department of Epidemiology (B.M.P.), and Department of Health Services (B.M.P.), University of Washington, Seattle, WA; Institute for Molecular Medicine (A.Y.J., M.F.) and Human Genetics Center (M.F.), University of Texas Health Science Center at Houston; Department of Neurology, Boston University School of Medicine, Boston, MA (A.L.d.S., S.S.); Department of Biostatistics, Boston University School of Public Health, Boston, MA (A.L.d.S.); The National Heart, Lung and

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006951PMC
February 2014

Traumatic brain injury and stroke.

Authors:
James F Meschia

Mayo Clin Proc 2014 Feb;89(2):142-3

Department of Neurology, Mayo Clinic, Jacksonville, FL. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2013.12.006DOI Listing
February 2014

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

Stroke 2014 Jan 21;45(1):24-36. Epub 2013 Nov 21.

From the Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany (M.D., R. Malik); Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.); Institut für Medizinische Biometrie und Statistik (I.R.K.), and Institut für integrative und experimentelle Genomik (J.E.), Universität zu Lübeck, Lübeck, Germany; Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Germany (I.R.K.); Department of Neurology and Center for Human Genetic Research (J.R.), and Cardiology Division (C.J.O.D.), Massachusetts General Hospital, Boston; Harvard Medical School, Boston, MA (J.R.); Program in Medical and Population Genetics (J.R.), and Program in Medical and Population Genetics (S.K.), Broad Institute of Harvard and MIT, Cambridge, MA; Clinical Trial Service Unit and Epidemiological Studies Unit (R.C., J.C.H.), Wellcome Trust Centre for Human Genetics (H.W., M. Farrall), Department of Cardiovascular Medicine (M. Farrall), and Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience (P.M.R.), John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom; deCODE Genetics, Reykjavik, Iceland (S.G., G.T., U.T., K.S.); Department of Medicine, University of Maryland School of Medicine, Baltimore (B.D.M.); Department of Medicine, Stanford University School of Medicine, Stanford, CA (T.L.A.); Center for Translational Neuroscience and Mental Health Research, University of Newcastle, New South Wales, Australia (C.L.); Hunter Medical Research Institute, New South Wales, Australia (C.L.); National Heart, Lung and Blood Institute and NHLBI's Framingham Heart Study, MA (C.J.O.D., S.S.); University of Texas Health Science Center at Houston (M. Fornage); Cardiovascular Health Research Unit, Department of Epidemiology (B.M.P.), Department of Medicine (B.M.P.), Department of Health Services (B.M.P.), and Cardiovascular Health Research Unit, Department of Medicine (J.C.B.), University

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http://dx.doi.org/10.1161/STROKEAHA.113.002707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112102PMC
January 2014

Asymptomatic carotid stenosis: What we can learn from the next generation of randomized clinical trials.

JRSM Cardiovasc Dis 2014 Jan 8;3:2048004014529419. Epub 2014 Apr 8.

Mayo Clinic, Department of Neurology, Jacksonville, FL, USA.

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http://dx.doi.org/10.1177/2048004014529419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157468PMC
January 2014

Genetics of ischaemic stroke.

J Neurol Neurosurg Psychiatry 2013 Dec 25;84(12):1302-8. Epub 2013 Apr 25.

Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College London, , London, UK.

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December 2013

Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.

Stroke 2013 Oct 10;44(10):2694-702. Epub 2013 Sep 10.

From the Mayo Clinic Jacksonville, FL (J.F.M.); University of Alabama at Birmingham (D.K.A., L.A.M.); Mayo Clinic Rochester, MN (R.D.B.); Massachusetts General Hospital, Boston, MA (H.A., J.R., O.W.); University of British Columbia, Vancouver, British Columbia, Canada (O.R.B.); University of Maryland School of Medicine and Veterans Administration Medical Center, Baltimore, MD (J.W.C., P.F.M., B.D.M., A.R.S., S.J.K.); University Medical Center Utrecht, Utrecht, The Netherlands (P.I.W.d.B.); Brigham and Women's Hospital, Harvard Medical School, Boston, MA (P.I.W.d.B.); Broad Institute of Harvard, MIT, Cambridge, MA (P.I.W.d.B.); Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany (M.D.); Johns Hopkins University, Baltimore, MD (K.F.D.); University of Texas Health Science Center at Houston (M.F.); Saint Francis Medical Center, Lynwood, CA (R.P.G.); NINDS Neurogenetics Cluster, Bethesda, MD (K.G.); IMIM-Hospital Universitari del Mar, Barcelona, Spain (J.J.C.); University of Florida, College of Pharmacy, Gainesville, FL (J.A.J.); Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Sweden (K.J., C.J.); University of Washington, Seattle, WA (C.C.L.); Washington University School of Medicine, St. Louis, MO (J.-M.L.); Lund University, Lund, Sweden (A.L.); St. George's University of London, London, United Kingdom (H.S.M.); Medical University Graz, Graz, Austria (R.S.); Brigham and Women's Hospital, Boston, MA (K.M.R.); University of Virginia, Charlottesville, VA (S.S.R., B.B.W.); Radcliffe Infirmary, Oxford, England (P.M.R.); University of Miami, Coral Gables, FL (T.R., R.L.S.); Imperial College London, London, United Kingdom (P.S.); Jagiellonian University, Krakow, Poland (A.S.); Albert Einstein College of Medicine, Bronx, NY (S.W.-S.); University of Edinburgh, Edinburgh, United Kingdom (C.S.); Universitaire Ziekenhuizen Leuven, Leuven, Belgium (V.N.S.T.); and University of Cincinnati, Cincinnati, OH (

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056331PMC
October 2013

Raising the red flag over white-matter changes.

Authors:
James F Meschia

Lancet Neurol 2013 Sep 12;12(9):841-842. Epub 2013 Jul 12.

Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address:

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September 2013

Reperfusion therapy for acute ischemic stroke: how should we react to the Third Interventional Management of Stroke (IMS III) trial?

Mayo Clin Proc 2013 Jul 29;88(7):653-7. Epub 2013 May 29.

Department of Neurology, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1016/j.mayocp.2013.05.002DOI Listing
July 2013

Genetics of stroke: impact and limitations of evolving technology: introduction.

Stroke 2013 Jun;44(6 Suppl 1):S16

Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1161/STROKEAHA.112.680041DOI Listing
June 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Authors:
Anna Köttgen Eva Albrecht Alexander Teumer Veronique Vitart Jan Krumsiek Claudia Hundertmark Giorgio Pistis Daniela Ruggiero Conall M O'Seaghdha Toomas Haller Qiong Yang Toshiko Tanaka Andrew D Johnson Zoltán Kutalik Albert V Smith Julia Shi Maksim Struchalin Rita P S Middelberg Morris J Brown Angelo L Gaffo Nicola Pirastu Guo Li Caroline Hayward Tatijana Zemunik Jennifer Huffman Loic Yengo Jing Hua Zhao Ayse Demirkan Mary F Feitosa Xuan Liu Giovanni Malerba Lorna M Lopez Pim van der Harst Xinzhong Li Marcus E Kleber Andrew A Hicks Ilja M Nolte Asa Johansson Federico Murgia Sarah H Wild Stephan J L Bakker John F Peden Abbas Dehghan Maristella Steri Albert Tenesa Vasiliki Lagou Perttu Salo Massimo Mangino Lynda M Rose Terho Lehtimäki Owen M Woodward Yukinori Okada Adrienne Tin Christian Müller Christopher Oldmeadow Margus Putku Darina Czamara Peter Kraft Laura Frogheri Gian Andri Thun Anne Grotevendt Gauti Kjartan Gislason Tamara B Harris Lenore J Launer Patrick McArdle Alan R Shuldiner Eric Boerwinkle Josef Coresh Helena Schmidt Michael Schallert Nicholas G Martin Grant W Montgomery Michiaki Kubo Yusuke Nakamura Toshihiro Tanaka Patricia B Munroe Nilesh J Samani David R Jacobs Kiang Liu Pio D'Adamo Sheila Ulivi Jerome I Rotter Bruce M Psaty Peter Vollenweider Gerard Waeber Susan Campbell Olivier Devuyst Pau Navarro Ivana Kolcic Nicholas Hastie Beverley Balkau Philippe Froguel Tõnu Esko Andres Salumets Kay Tee Khaw Claudia Langenberg Nicholas J Wareham Aaron Isaacs Aldi Kraja Qunyuan Zhang Philipp S Wild Rodney J Scott Elizabeth G Holliday Elin Org Margus Viigimaa Stefania Bandinelli Jeffrey E Metter Antonio Lupo Elisabetta Trabetti Rossella Sorice Angela Döring Eva Lattka Konstantin Strauch Fabian Theis Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Marcel Bruinenberg Ronald P Stolk Jaspal S Kooner Weihua Zhang Bernhard R Winkelmann Bernhard O Boehm Susanne Lucae Brenda W Penninx Johannes H Smit Gary Curhan Poorva Mudgal Robert M Plenge Laura Portas Ivana Persico Mirna Kirin James F Wilson Irene Mateo Leach Wiek H van Gilst Anuj Goel Halit Ongen Albert Hofman Fernando Rivadeneira Andre G Uitterlinden Medea Imboden Arnold von Eckardstein Francesco Cucca Ramaiah Nagaraja Maria Grazia Piras Matthias Nauck Claudia Schurmann Kathrin Budde Florian Ernst Susan M Farrington Evropi Theodoratou Inga Prokopenko Michael Stumvoll Antti Jula Markus Perola Veikko Salomaa So-Youn Shin Tim D Spector Cinzia Sala Paul M Ridker Mika Kähönen Jorma Viikari Christian Hengstenberg Christopher P Nelson James F Meschia Michael A Nalls Pankaj Sharma Andrew B Singleton Naoyuki Kamatani Tanja Zeller Michel Burnier John Attia Maris Laan Norman Klopp Hans L Hillege Stefan Kloiber Hyon Choi Mario Pirastu Silvia Tore Nicole M Probst-Hensch Henry Völzke Vilmundur Gudnason Afshin Parsa Reinhold Schmidt John B Whitfield Myriam Fornage Paolo Gasparini David S Siscovick Ozren Polašek Harry Campbell Igor Rudan Nabila Bouatia-Naji Andres Metspalu Ruth J F Loos Cornelia M van Duijn Ingrid B Borecki Luigi Ferrucci Giovanni Gambaro Ian J Deary Bruce H R Wolffenbuttel John C Chambers Winfried März Peter P Pramstaller Harold Snieder Ulf Gyllensten Alan F Wright Gerjan Navis Hugh Watkins Jacqueline C M Witteman Serena Sanna Sabine Schipf Malcolm G Dunlop Anke Tönjes Samuli Ripatti Nicole Soranzo Daniela Toniolo Daniel I Chasman Olli Raitakari W H Linda Kao Marina Ciullo Caroline S Fox Mark Caulfield Murielle Bochud Christian Gieger

Nat Genet 2013 Feb 23;45(2):145-54. Epub 2012 Dec 23.

Renal Division, Freiburg University Hospital, Freiburg, Germany.

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http://dx.doi.org/10.1038/ng.2500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663712PMC
February 2013

Advances in stroke: genetics 2012.

Stroke 2013 Feb 15;44(2):309-10. Epub 2013 Jan 15.

Department of Neurology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA.

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February 2013