James F Leckman

James F Leckman

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James F Leckman

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Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome.

Biol Psychiatry 2019 Aug 13. Epub 2019 Aug 13.

Child Study Center, Yale School of Medicine, New Haven, Connecticut; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.07.035DOI Listing
August 2019

Not just in Philadelphia - But across the globe.

Depress Anxiety 2019 07 17;36(7):584-585. Epub 2019 May 17.

World Childhood Foundation USA, New York,, New York.

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http://dx.doi.org/10.1002/da.22905DOI Listing
July 2019

The impact of attention deficit hyperactivity disorder in obsessive-compulsive disorder subjects.

Depress Anxiety 2019 06 16;36(6):533-542. Epub 2019 Apr 16.

Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/da.22898
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http://dx.doi.org/10.1002/da.22898DOI Listing
June 2019

Oxytocin Enhances the Neural Efficiency of Social Perception.

Front Hum Neurosci 2019 11;13:71. Epub 2019 Mar 11.

Yale Child Study Center, School of Medicine, Yale University, New Haven, CT, United States.

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http://dx.doi.org/10.3389/fnhum.2019.00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421852PMC
March 2019

Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology?

J Am Acad Child Adolesc Psychiatry 2019 Feb 24;58(2):277-286.e4. Epub 2018 Nov 24.

Lifespan Brain Institute, Children's Hospital of Philadelphia and Penn Medicine, and the Neuropsychiatry Section of the Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1016/j.jaac.2018.06.038DOI Listing
February 2019

Attention and executive functions computer training for attention-deficit/hyperactivity disorder (ADHD): results from a randomized, controlled trial.

Eur Child Adolesc Psychiatry 2018 Dec 11;27(12):1563-1574. Epub 2018 Apr 11.

Department of Economics and Business, National Centre for Register-based Research, Aarhus University, Fuglesangs Allé 4, Aarhus, Denmark.

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http://dx.doi.org/10.1007/s00787-018-1151-yDOI Listing
December 2018

Genetic susceptibility in obsessive-compulsive disorder.

Handb Clin Neurol 2018 ;148:767-781

Child Study Center, Yale University School of Medicine, New Haven, CT, United States; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States; Department of Psychology, Yale University School of Medicine, New Haven, CT, United States; Integrated Neuroscience Research Program, Yale University School of Medicine, New Haven, CT, United States.

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http://dx.doi.org/10.1016/B978-0-444-64076-5.00049-1DOI Listing
August 2018

Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial.

J Anxiety Disord 2018 08 17;58:42-50. Epub 2018 Jul 17.

Department of Psychiatry, University of Sao Paulo Medical School, Sao Paulo, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.janxdis.2018.07.002DOI Listing
August 2018

Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS).

Eur Child Adolesc Psychiatry 2018 May 8;27(5):637-643. Epub 2017 Nov 8.

Section On Behavioral Pediatrics, National Institute of Mental Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s00787-017-1077-9DOI Listing
May 2018

A multicenter examination and strategic revisions of the Yale Global Tic Severity Scale.

Neurology 2018 05 13;90(19):e1711-e1719. Epub 2018 Apr 13.

From the Department of Psychiatry and Behavioral Sciences (J.F.M.), Johns Hopkins University School of Medicine, Baltimore, MD; Semel Institute of Neuroscience and Human Behavior (J.F.M., J.P., E.R., J.T.M.), University of California Los Angeles; Baylor College of Medicine (E.A.S.), Houston, TX; Departments of Pediatrics, Psychiatry and Behavioral Neuroscience (T.K.M., A.B.L.), University of South Florida, Tampa; All Children's Hospital (T.K.M.), Johns Hopkins Medicine, Baltimore, MD; Marquette University (D.W.W.), Milwaukee, WI; Weill Cornell Medical College (J.W.W.), Cornell University, New York, NY; Department of Psychiatry (A.L.P.), University of Texas Health Science Center at San Antonio; South Texas Veterans Health Care System (A.L.P.), San Antonio; Massachusetts General Hospital and Harvard Medical School (S.W.), Boston; Yale Child Study Center (J.F.L.), New Haven, CT; and Marcus Autism Center (L.S.), Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1212/WNL.0000000000005474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952973PMC
May 2018

Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatum.

Brain Behav Immun 2018 03 9;69:304-311. Epub 2017 Dec 9.

Department of Psychiatry, Yale University, United States; Department of Psychology, Yale University, United States; Child Study Center, Yale University, United States; Interdepartmental Neuroscience Program, Yale University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857467PMC
March 2018

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

Transl Psychiatry 2018 01 10;8(1):15. Epub 2018 Jan 10.

The Ludmer Centre for Neuroinformatics and Mental Health, Douglas Hospital Research Centre and Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, QC, H4H1R3, Canada.

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http://dx.doi.org/10.1038/s41398-017-0063-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802588PMC
January 2018

What Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy?

Authors:
James F Leckman

J Am Acad Child Adolesc Psychiatry 2017 11;56(11):914-915

Yale Child Study Center, New Haven, CT. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08908567173167
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http://dx.doi.org/10.1016/j.jaac.2017.09.421DOI Listing
November 2017

A double-blind randomized pilot trial comparing computerized cognitive exercises to Tetris in adolescents with attention-deficit/hyperactivity disorder.

Nord J Psychiatry 2017 Aug 9;71(6):455-464. Epub 2017 Jun 9.

a Department of Clinical Research , University of Southern Denmark , Odense , Denmark.

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http://dx.doi.org/10.1080/08039488.2017.1328070DOI Listing
August 2017

Risk of Irritability With Psychostimulant Treatment in Children With ADHD: A Meta-Analysis.

J Clin Psychiatry 2017 Jun;78(6):e648-e655

Child Study Center, Yale University School of Medicine, PO Box 207900, New Haven, CT 06520.

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http://dx.doi.org/10.4088/JCP.15r10601DOI Listing
June 2017

Mortality risk in a nationwide cohort of individuals with tic disorders and with tourette syndrome.

Mov Disord 2017 04 24;32(4):605-609. Epub 2017 Mar 24.

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.

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http://dx.doi.org/10.1002/mds.26939DOI Listing
April 2017

Systematic review of severity scales and screening instruments for tics: Critique and recommendations.

Mov Disord 2017 03 10;32(3):467-473. Epub 2017 Jan 10.

National Center of Epidemiology and Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas, Carlos III Institute of Health, Madrid, Spain.

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http://dx.doi.org/10.1002/mds.26891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482361PMC
March 2017

Gilles de la Tourette syndrome.

Nat Rev Dis Primers 2017 Feb 2;3:16097. Epub 2017 Feb 2.

Department of Psychiatry, Pediatrics, and Psychology, Child Study Center, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nrdp.2016.97DOI Listing
February 2017

Nurturing care: promoting early childhood development.

Lancet 2017 01 4;389(10064):91-102. Epub 2016 Oct 4.

Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan; Center for Global Child Health, The Hospital for Sick Children, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736163139
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http://dx.doi.org/10.1016/S0140-6736(16)31390-3DOI Listing
January 2017

A preliminary study of movement intensity during a Go/No-Go task and its association with ADHD outcomes and symptom severity.

Child Adolesc Psychiatry Ment Health 2016 12;10:47. Epub 2016 Dec 12.

Child Study Center, Yale University School of Medicine, I-265 SHM, 230 South Frontage Road, New Haven, CT 06520-7900 USA.

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http://dx.doi.org/10.1186/s13034-016-0135-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153899PMC
December 2016

Prenatal and Perinatal Risk Factors and the Promise of Birth Cohort Studies: Origins of Obsessive-Compulsive Disorder.

JAMA Psychiatry 2016 11;73(11):1117-1118

Child Study Center, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.2092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180419PMC
November 2016

Understanding the covariation of tics, attention-deficit/hyperactivity, and obsessive-compulsive symptoms: A population-based adult twin study.

Am J Med Genet B Neuropsychiatr Genet 2016 10 27;171(7):938-47. Epub 2016 Feb 27.

Centre for Psychiatric Research and Education, Department of Clinical Neuroscience, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1002/ajmg.b.32436DOI Listing
October 2016

Cross-generational influences on childhood anxiety disorders: pathways and mechanisms.

J Neural Transm (Vienna) 2016 09 4;123(9):1053-67. Epub 2016 May 4.

Gonda Brain Research, Bar Ilan University, Ramat Gan, Israel.

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http://dx.doi.org/10.1007/s00702-016-1565-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007197PMC
September 2016

The Origins of Tourette Syndrome: Prenatal Risk Factors and the Promise of Birth Cohort Studies.

J Am Acad Child Adolesc Psychiatry 2016 09;55(9):751-3

Child Study Center, Yale University School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1016/j.jaac.2016.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180440PMC
September 2016

Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS).

J Clin Sleep Med 2016 07 15;12(7):1027-32. Epub 2016 Jul 15.

Department of Pediatrics and Developmental Neuroscience, National Institute of Mental Health, Bethesda, MD.

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http://dx.doi.org/10.5664/jcsm.5942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918985PMC
July 2016

N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial.

J Child Adolesc Psychopharmacol 2016 05 30;26(4):327-34. Epub 2016 Mar 30.

1 Yale Child Study Center and the Department of Psychiatry of Yale University , New Haven, Connecticut.

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http://dx.doi.org/10.1089/cap.2015.0109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445198PMC
May 2016

Transcriptome Analysis of the Human Striatum in Tourette Syndrome.

Biol Psychiatry 2016 Mar 24;79(5):372-382. Epub 2014 Jul 24.

Program in Neurodevelopment and Regeneration, Yale University School of Medicine, New Haven, Connecticut; Yale Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut; Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00063223140055
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http://dx.doi.org/10.1016/j.biopsych.2014.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305353PMC
March 2016

Successful Treatment of Tourette Syndrome With Electroconvulsive Therapy: A Case Report.

Biol Psychiatry 2016 Mar 5;79(5):e13-e14. Epub 2014 Oct 5.

Department of Psychiatry (JNG, JSK, RBO), Yale University School of Medicine, New Haven, Connecticut.. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.09.020DOI Listing
March 2016

Deep Brain Stimulation for Tourette Syndrome: Lessons Learned and Future Directions.

Authors:
James F Leckman

Biol Psychiatry 2016 Mar;79(5):343-344

Child Study Center and Departments of Psychiatry, Pediatrics, and Psychology, Yale University, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.11.028DOI Listing
March 2016

Obsessive-compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children.

Eur Child Adolesc Psychiatry 2016 Feb 27;25(2):175-82. Epub 2015 May 27.

Department and Institute of Psychiatry, University of Sao Paulo Medical School (USP), Rua Dr. Ovídio Pires de Campos, 785, São Paulo, SP, 01060-970, Brazil.

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http://dx.doi.org/10.1007/s00787-015-0723-3DOI Listing
February 2016

Violence, health, and South-North collaboration: Interdisciplinary research in light of the 2030 Agenda.

Soc Sci Med 2015 Dec 23;146:236-42. Epub 2015 Oct 23.

Law and Psychiatry Division, Yale University, 34 Park Street, New Haven, CT 06519, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S02779536150043
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http://dx.doi.org/10.1016/j.socscimed.2015.10.029DOI Listing
December 2015

A Prospective Longitudinal Study of Perceived Infant Outcomes at 18-24 Months: Neural and Psychological Correlates of Parental Thoughts and Actions Assessed during the First Month Postpartum.

Front Psychol 2015 20;6:1772. Epub 2015 Nov 20.

Child Study Center, Yale University School of Medicine New Haven, CT, USA ; Department of Psychiatry, Psychology, Center for Human Growth and Development, Women and Infants Mental Health Program, University of Michigan Ann Arbor, MI, USA.

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http://dx.doi.org/10.3389/fpsyg.2015.01772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654106PMC
December 2015

Cognitive computer training in children with attention deficit hyperactivity disorder (ADHD) versus no intervention: study protocol for a randomized controlled trial.

Trials 2015 Oct 24;16:480. Epub 2015 Oct 24.

Department of Economics and Business, National Centre for Register-based Research, Aarhus University, Fuglesangs Allé 4, Aarhus, Denmark.

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http://www.trialsjournal.com/content/16/1/480
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http://dx.doi.org/10.1186/s13063-015-0975-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619562PMC
October 2015

Meta-Analysis: Risk of Tics Associated With Psychostimulant Use in Randomized, Placebo-Controlled Trials.

J Am Acad Child Adolesc Psychiatry 2015 Sep 2;54(9):728-36. Epub 2015 Jul 2.

Yale Child Study Center and Yale University. Electronic address:

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http://dx.doi.org/10.1016/j.jaac.2015.06.011DOI Listing
September 2015

Editorial commentary: "What does immunology have to do with brain development and neuropsychiatric disorders?".

Brain Res 2015 Aug 8;1617:1-6. Epub 2014 Oct 8.

Program in Neurodevelopment and Regeneration, Yale Kavli Institute for Neuroscience, Child Study Center and Department of Neurobiology, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1016/j.brainres.2014.09.052DOI Listing
August 2015

Familial Risks of Tourette Syndrome and Chronic Tic Disorders. A Population-Based Cohort Study.

JAMA Psychiatry 2015 Aug;72(8):787-93

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.0627DOI Listing
August 2015

Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort study.

Lancet Psychiatry 2015 Aug 22;2(8):702-709. Epub 2015 Jul 22.

Department of Economics and Business, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark.

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http://www.thelancet.com/pdfs/journals/lanpsy/PIIS2215-0366(
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http://linkinghub.elsevier.com/retrieve/pii/S221503661500271
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http://dx.doi.org/10.1016/S2215-0366(15)00271-0DOI Listing
August 2015

Maternal history of autoimmune disease and later development of tourette syndrome in offspring.

J Am Acad Child Adolesc Psychiatry 2015 Jun 17;54(6):495-501.e1. Epub 2015 Mar 17.

NCRR, School of Business and Social Sciences, Aarhus University, and the Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH.

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http://dx.doi.org/10.1016/j.jaac.2015.03.008DOI Listing
June 2015

Oxytocin-augmented labor and risk for autism in males.

Behav Brain Res 2015 May 20;284:207-12. Epub 2015 Feb 20.

National Centre for Register-Based Research, Department of Economics and Business, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus and Copenhagen, Denmark; Department for Child and Adolescent Psychiatry, Hospital of Telemark, Kragerø, Norway.

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http://pure.au.dk/portal/files/89940523/1_s2.0_S016643281500
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http://linkinghub.elsevier.com/retrieve/pii/S016643281500107
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http://dx.doi.org/10.1016/j.bbr.2015.02.028DOI Listing
May 2015

Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort study.

Lancet 2015 May 26;385(9983):2190-6. Epub 2015 Feb 26.

National Centre for Register-Based Research, Department of Economics and Business, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus and Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736146168
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http://dx.doi.org/10.1016/S0140-6736(14)61684-6DOI Listing
May 2015

Neural plasticity in fathers of human infants.

Soc Neurosci 2014 24;9(5):522-35. Epub 2014 Jun 24.

a Department of Psychology , University of Denver , Denver , CO , USA.

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http://dx.doi.org/10.1080/17470919.2014.933713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144350PMC
March 2015

Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children.

J Psychiatr Res 2015 Mar 12;62:108-14. Epub 2015 Feb 12.

National Institute of Developmental Psychiatry for Children and Adolescents, CNPq, Rua. Dr. Ovídio Pires de Campos, São Paulo 01060-970, SP, Brazil; Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo (UNIFESP), Rua Pedro de Toledo, 590, São Paulo 04038-020, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2015.01.018DOI Listing
March 2015

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Authors:
Dongmei Yu Carol A Mathews Jeremiah M Scharf Benjamin M Neale Lea K Davis Eric R Gamazon Eske M Derks Patrick Evans Christopher K Edlund Jacquelyn Crane Jesen A Fagerness Lisa Osiecki Patience Gallagher Gloria Gerber Stephen Haddad Cornelia Illmann Lauren M McGrath Catherine Mayerfeld Sampath Arepalli Cristina Barlassina Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrió O Joseph Bienvenu Donald W Black Michael H Bloch Helena Brentani Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond D Campbell Carolina Cappi Julio C Cardona Silgado Maria C Cavallini Denise A Chavira Sylvain Chouinard Edwin H Cook M R Cookson Vladimir Coric Bernadette Cullen Daniele Cusi Richard Delorme Damiaan Denys Yves Dion Valsama Eapen Karin Egberts Peter Falkai Thomas Fernandez Eduardo Fournier Helena Garrido Daniel Geller Donald L Gilbert Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt John Hardy Gary A Heiman Sian M J Hemmings Luis D Herrera Dianne M Hezel Pieter J Hoekstra Joseph Jankovic James L Kennedy Robert A King Anuar I Konkashbaev Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Sara Lupoli Fabio Macciardi Wolfgang Maier Paolo Manunta Maurizio Marconi James T McCracken Sandra C Mesa Restrepo Rainald Moessner Priya Moorjani Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden Erika Nurmi William Cornejo Ochoa Roel A Ophoff Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosário David Rosenberg Stephan Ruhrmann Chiara Sabatti Erika Salvi Aline S Sampaio Jack Samuels Paul Sandor Susan K Service Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Eric Strengman Jay A Tischfield Maurizio Turiel Ana V Valencia Duarte Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Mike Weale Robert Weiss Jens R Wendland Herman G M Westenberg Yin Yao Shugart Ana G Hounie Euripedes C Miguel Humberto Nicolini Michael Wagner Andres Ruiz-Linares Danielle C Cath William McMahon Danielle Posthuma Ben A Oostra Gerald Nestadt Guy A Rouleau Shaun Purcell Michael A Jenike Peter Heutink Gregory L Hanna David V Conti Paul D Arnold Nelson B Freimer S Evelyn Stewart James A Knowles Nancy J Cox David L Pauls

Am J Psychiatry 2015 Jan 31;172(1):82-93. Epub 2014 Oct 31.

From the Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston; the Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Mass.; the Department of Psychiatry, University of California, San Francisco; the Department of Neurology, Massachusetts General Hospital, Boston; the Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston; the Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago; the Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam; the Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles; the Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Md.; the Genomic and Bioinformatic Unit, Filarete Foundation, Milan, Italy; the Department of Health Sciences, Graduate School of Nephrology, University of Milan, Milan; the Toronto Western Research Institute, University Health Network, Toronto; Hospital for Sick Children, Toronto; Università Vita-Salute San Raffaele, Milan; the Herman Dana Division of Child and Adolescent Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem; Universidad de Antioquia, Universidad Pontificia Bolivariana, Medellín, Colombia; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; the Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.; the Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; North Shore-Long Island Jewish Medical Center and North Shore-Lo

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http://dx.doi.org/10.1176/appi.ajp.2014.13101306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282594PMC
January 2015

Practitioner review: Engaging fathers--recommendations for a game change in parenting interventions based on a systematic review of the global evidence.

J Child Psychol Psychiatry 2014 Nov 1;55(11):1187-212. Epub 2014 Jul 1.

Department of Anthropology & Jackson Institute, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1111/jcpp.12280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277854PMC
November 2014

Clinical Features of Tourette Syndrome and Tic Disorders.

J Obsessive Compuls Relat Disord 2014 Oct 26;3(4):372-379. Epub 2014 Mar 26.

Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22113649140002
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http://dx.doi.org/10.1016/j.jocrd.2014.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124690PMC
October 2014

Pediatric acute-onset neuropsychiatric syndrome.

Psychiatr Clin North Am 2014 Sep;37(3):353-74

Child Study Center, Yale University School of Medicine, 230 S Frontage Road, New Haven, CT 06520, USA.

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http://www.pandasitalia.it/wp-content/uploads/2015/02/PANS-P
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http://linkinghub.elsevier.com/retrieve/pii/S0193953X1400055
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http://dx.doi.org/10.1016/j.psc.2014.06.001DOI Listing
September 2014

Cardiovascular safety of stimulants in children with attention-deficit/hyperactivity disorder: a nationwide prospective cohort study.

J Child Adolesc Psychopharmacol 2014 Aug 23;24(6):302-10. Epub 2014 Jun 23.

1 National Centre for Register-based Research, School of Business and Social Sciences, Department of Economics and Business, Aarhus University , Aarhus, Denmark .

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http://dx.doi.org/10.1089/cap.2014.0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137345PMC
August 2014

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

Authors:
Lauren M McGrath Dongmei Yu Christian Marshall Lea K Davis Bhooma Thiruvahindrapuram Bingbin Li Carolina Cappi Gloria Gerber Aaron Wolf Frederick A Schroeder Lisa Osiecki Colm O'Dushlaine Andrew Kirby Cornelia Illmann Stephen Haddad Patience Gallagher Jesen A Fagerness Cathy L Barr Laura Bellodi Fortu Benarroch O Joseph Bienvenu Donald W Black Michael H Bloch Ruth D Bruun Cathy L Budman Beatriz Camarena Danielle C Cath Maria C Cavallini Sylvain Chouinard Vladimir Coric Bernadette Cullen Richard Delorme Damiaan Denys Eske M Derks Yves Dion Maria C Rosário Valsama Eapen Patrick Evans Peter Falkai Thomas V Fernandez Helena Garrido Daniel Geller Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt Gary A Heiman Sian M J Hemmings Luis D Herrera Ana G Hounie Joseph Jankovic James L Kennedy Robert A King Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Christine Lochner Thomas L Lowe Gholson J Lyon Fabio Macciardi Wolfgang Maier James T McCracken William McMahon Dennis L Murphy Allan L Naarden Benjamin M Neale Erika Nurmi Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Victor I Reus Margaret A Richter Mark Riddle Mary M Robertson David Rosenberg Guy A Rouleau Stephan Ruhrmann Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Jay A Tischfield Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Jens R Wendland Yin Yao Shugart Euripedes C Miguel Humberto Nicolini Ben A Oostra Rainald Moessner Michael Wagner Andres Ruiz-Linares Peter Heutink Gerald Nestadt Nelson Freimer Tracey Petryshen Danielle Posthuma Michael A Jenike Nancy J Cox Gregory L Hanna Helena Brentani Stephen W Scherer Paul D Arnold S Evelyn Stewart Carol A Mathews James A Knowles Edwin H Cook David L Pauls Kai Wang Jeremiah M Scharf

J Am Acad Child Adolesc Psychiatry 2014 Aug 24;53(8):910-9. Epub 2014 Jun 24.

Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address:

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http://dx.doi.org/10.1016/j.jaac.2014.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218748PMC
August 2014

Neuroendocrine aspects of Tourette syndrome.

Int Rev Neurobiol 2013 ;112:239-79

Queen Elizabeth Hospital, Woolwich, London, United Kingdom; Centre for Neuroscience and Trauma, Queen Mary University of London, London, United Kingdom; King's College Hospital, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-411546-0.00009-3DOI Listing
July 2014

Gender and injuries predict stimulant medication use.

J Child Adolesc Psychopharmacol 2014 Jun 9;24(5):253-9. Epub 2014 May 9.

1 National Centre for Register-Based Research, Department of Economics and Business, Aarhus University , Aarhus, Denmark .

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http://dx.doi.org/10.1089/cap.2013.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064734PMC
June 2014

Commentary: What does immunology have to do with brain development and psychopathology?--a commentary on O'Connor et al. (2014).

Authors:
James F Leckman

J Child Psychol Psychiatry 2014 Jun;55(6):632-4

Child Study Center, Departments of Psychiatry, Pediatrics and Psychology, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1111/jcpp.12259DOI Listing
June 2014

The Modulating Role of Stress in the Onset and Course of Tourette's Syndrome: A Review.

Behav Modif 2014 Mar 10;38(2):184-216. Epub 2014 Feb 10.

Department of Child and Adolescent Psychiatry, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Germany

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http://p113367.typo3server.info/uploads/media/Buse_et_al_201
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http://bmo.sagepub.com/cgi/doi/10.1177/0145445514522056
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http://dx.doi.org/10.1177/0145445514522056DOI Listing
March 2014

From attachment to groups: tapping into the neurobiology of our interconnectedness.

J Am Acad Child Adolesc Psychiatry 2014 Feb;53(2):130-2

School of Medicine, Yale University.

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http://dx.doi.org/10.1016/j.jaac.2013.10.012DOI Listing
February 2014

Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease.

J Immunol 2013 Dec 1;191(11):5524-41. Epub 2013 Nov 1.

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Biomedical Research Center, Oklahoma City, OK 73104;

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http://dx.doi.org/10.4049/jimmunol.1102592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848617PMC
December 2013

Oxytocin enhances brain function in children with autism.

Proc Natl Acad Sci U S A 2013 Dec 2;110(52):20953-8. Epub 2013 Dec 2.

Center for Translational Developmental Neuroscience, Yale Child Study Center, Yale University, New Haven, CT 06520.

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http://dx.doi.org/10.1073/pnas.1312857110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876263PMC
December 2013

The risks and benefits of antidepressants to treat pediatric-onset depression and anxiety disorders: a developmental perspective.

Authors:
James F Leckman

Psychother Psychosom 2013 21;82(3):129-31. Epub 2013 Mar 21.

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http://dx.doi.org/10.1159/000345543DOI Listing
November 2013

Gene variants associated with antisocial behaviour: a latent variable approach.

J Child Psychol Psychiatry 2013 Oct 3;54(10):1074-85. Epub 2013 Jul 3.

Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1111/jcpp.12109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766409PMC
October 2013

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.

Authors:
Lea K Davis Dongmei Yu Clare L Keenan Eric R Gamazon Anuar I Konkashbaev Eske M Derks Benjamin M Neale Jian Yang S Hong Lee Patrick Evans Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrio Oscar J Bienvenu Michael H Bloch Rianne M Blom Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond Campbell Carolina Cappi Julio C Cardona Silgado Danielle C Cath Maria C Cavallini Denise A Chavira Sylvain Chouinard David V Conti Edwin H Cook Vladimir Coric Bernadette A Cullen Dieter Deforce Richard Delorme Yves Dion Christopher K Edlund Karin Egberts Peter Falkai Thomas V Fernandez Patience J Gallagher Helena Garrido Daniel Geller Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Stephen Haddad Gary A Heiman Sian M J Hemmings Ana G Hounie Cornelia Illmann Joseph Jankovic Michael A Jenike James L Kennedy Robert A King Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Fabio Macciardi James T McCracken Lauren M McGrath Sandra C Mesa Restrepo Rainald Moessner Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden William Cornejo Ochoa Roel A Ophoff Lisa Osiecki Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias J Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosàrio David Rosenberg Guy A Rouleau Stephan Ruhrmann Andres Ruiz-Linares Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein E Strengman Jay A Tischfield Ana V Valencia Duarte Homero Vallada Filip Van Nieuwerburgh Jeremy Veenstra-Vanderweele Susanne Walitza Ying Wang Jens R Wendland Herman G M Westenberg Yin Yao Shugart Euripedes C Miguel William McMahon Michael Wagner Humberto Nicolini Danielle Posthuma Gregory L Hanna Peter Heutink Damiaan Denys Paul D Arnold Ben A Oostra Gerald Nestadt Nelson B Freimer David L Pauls Naomi R Wray S Evelyn Stewart Carol A Mathews James A Knowles Nancy J Cox Jeremiah M Scharf

PLoS Genet 2013 Oct 24;9(10):e1003864. Epub 2013 Oct 24.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812053PMC
October 2013

Trajectory in obsessive-compulsive disorder comorbidities.

Eur Neuropsychopharmacol 2013 Jul 22;23(7):594-601. Epub 2012 Aug 22.

Department of Psychiatry, University of São Paulo Medical School, SP, Brazil.

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http://dx.doi.org/10.1016/j.euroneuro.2012.08.006DOI Listing
July 2013

Clinical assessment of Tourette syndrome and tic disorders.

Neurosci Biobehav Rev 2013 Jul 1;37(6):997-1007. Epub 2012 Dec 1.

Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.neubiorev.2012.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674220PMC
July 2013

What's next for developmental psychiatry?

Authors:
James F Leckman

World Psychiatry 2013 Jun;12(2):125-6

Child Study Center, Yale University, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1002/wps.20029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683258PMC
June 2013

N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial.

J Am Acad Child Adolesc Psychiatry 2013 Mar;52(3):231-40

Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.jaac.2012.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745012PMC
March 2013

More than two dozen "autisms".

Braz J Psychiatry 2013 Mar;35(1):3-4

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http://dx.doi.org/10.1016/j.rbp.2013.01.003DOI Listing
March 2013

Developmental approaches to child psychopathology: longitudinal studies and implications for clinical practice.

J Can Acad Child Adolesc Psychiatry 2013 Feb;22(1):3-5

Department of Psychiatry and Centre de Recherche du CHU Ste-Justine, Université de Montréal, Montréal, Québec.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565708PMC
February 2013

EARLY POSTPARTUM PARENTAL PREOCCUPATION AND POSITIVE PARENTING THOUGHTS: RELATIONSHIP WITH PARENT-INFANT INTERACTION.

Infant Ment Health J 2013 Mar-Apr;34(2):104-116. Epub 2012 Sep 25.

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1002/imhj.21359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732877PMC
September 2012

Oxytocin during the initial stages of romantic attachment: relations to couples' interactive reciprocity.

Psychoneuroendocrinology 2012 Aug 26;37(8):1277-85. Epub 2012 Jan 26.

Department of Psychology and the Gonda Brain Sciences Center, Bar-Ilan University, Ramat-Gan, Israel.

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http://dx.doi.org/10.1016/j.psyneuen.2011.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936960PMC
August 2012

Editorial commentary: challenges and potential of DSM-5 and ICD-11 revisions.

J Child Psychol Psychiatry 2012 May;53(5):449-53

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http://dx.doi.org/10.1111/j.1469-7610.2012.02548.xDOI Listing
May 2012

Tic disorders.

Authors:
James F Leckman

BMJ 2012 Jan 5;344:d7659. Epub 2012 Jan 5.

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http://dx.doi.org/10.1136/bmj.d7659DOI Listing
January 2012

Variations in maternal behavior--oxytocin and reward pathways--peripheral measures matter?!

Authors:
James F Leckman

Neuropsychopharmacology 2011 Dec;36(13):2587-8

Child Study Center, Yale University School of Medicine, New Haven, CT 06520-7900, USA.

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http://dx.doi.org/10.1038/npp.2011.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230502PMC
December 2011

Love alters autonomic reactivity to emotions.

Emotion 2011 Dec;11(6):1314-21

Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan, Israel.

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http://dx.doi.org/10.1037/a0024090DOI Listing
December 2011

Coercive and disruptive behaviors in pediatric obsessive-compulsive disorder.

Depress Anxiety 2011 Oct 18;28(10):899-905. Epub 2011 Jul 18.

Yale Child Study Center, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1002/da.20858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006629PMC
October 2011

Oxytocin and social motivation.

Dev Cogn Neurosci 2011 Oct;1(4):471-93

Child Study Center, Yale University, New Haven, CT 06520-7900, USA.

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http://dx.doi.org/10.1016/j.dcn.2011.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185363PMC
October 2011

Thank goodness for Uncle Sam and the National Institute of Mental Health Intramural Program.

Authors:
James F Leckman

J Am Acad Child Adolesc Psychiatry 2011 Sep;50(9):851-3

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http://dx.doi.org/10.1016/j.jaac.2010.04.012DOI Listing
September 2011