James E Gern

James E Gern

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James E Gern

James E Gern

Publications by authors named "James E Gern"

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Human airway epithelial cells express a functional IL-5 receptor.

Allergy 2020 Aug 14;75(8). Epub 2020 Apr 14.

Division of Allergy, Department of Medicine, Pulmonary and Critical Care Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

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http://dx.doi.org/10.1111/all.14297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387204PMC
August 2020

Cadherin-related family member 3 upregulates the effector functions of eosinophils.

Allergy 2020 Jul 3;75(7):1805-1809. Epub 2020 Mar 3.

Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1111/all.14229DOI Listing
July 2020

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2.

J Allergy Clin Immunol 2020 Jul 22;146(1):203-206.e3. Epub 2020 Apr 22.

Department of Medicine, University of Washington, Seattle, Wash; Benaroya Research Institute, Systems Immunology Division, Seattle, Wash.

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http://dx.doi.org/10.1016/j.jaci.2020.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175851PMC
July 2020

Patterns of farm exposure are associated with reduced incidence of atopic dermatitis in early life.

J Allergy Clin Immunol 2020 Jul 7. Epub 2020 Jul 7.

University of Wisconsin School of Medicine and Public Health, Madison, Wis. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.06.025DOI Listing
July 2020

Immune responses to rhinoviruses and asthma: Are we 3 steps closer to the door?

Authors:
James E Gern

J Allergy Clin Immunol 2020 Jul 14. Epub 2020 Jul 14.

Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, Wis. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.06.031DOI Listing
July 2020

Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study.

Pediatr Allergy Immunol 2020 May 27. Epub 2020 May 27.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/pai.13296DOI Listing
May 2020

Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children.

Pediatr Infect Dis J 2020 04;39(4):283-286

From the Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.

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http://dx.doi.org/10.1097/INF.0000000000002570DOI Listing
April 2020

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.

Cell Host Microbe 2020 04 3;27(4):614-628.e6. Epub 2020 Mar 3.

Department of Pediatrics, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Medical Microbiology and Immunology University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305569PMC
April 2020

Association of rhinovirus species with nasopharyngeal metabolome in bronchiolitis infants: A multicenter study.

Allergy 2020 Apr 18. Epub 2020 Apr 18.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/all.14326DOI Listing
April 2020

Ecological and individual data both indicate that influenza inhibits rhinovirus infection.

Proc Natl Acad Sci U S A 2020 03 3;117(13):6987. Epub 2020 Mar 3.

Department of Pediatrics, University of Wisconsin-Madison, Madison, WI 53792.

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http://dx.doi.org/10.1073/pnas.1922920117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132294PMC
March 2020

Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma.

J Allergy Clin Immunol Pract 2020 Feb 11;8(2):588-595.e4. Epub 2019 Sep 11.

Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012669PMC
February 2020

Exacerbation-Prone Asthma.

J Allergy Clin Immunol Pract 2020 Feb 22;8(2):474-482. Epub 2019 Nov 22.

Department of Pediatrics, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaip.2019.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942520PMC
February 2020

Influence of whey protein hydrolysis in combination with dextran glycation on immunoglobulin E binding capacity with blood sera obtained from patients with a cow milk protein allergy.

J Dairy Sci 2020 Feb 27;103(2):1141-1150. Epub 2019 Nov 27.

Center for Dairy Research, University of Wisconsin-Madison, 53706. Electronic address:

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http://dx.doi.org/10.3168/jds.2019-17187DOI Listing
February 2020

Reply.

J Allergy Clin Immunol 2019 06 9;143(6):2334-2335. Epub 2019 Apr 9.

University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2019.03.006DOI Listing
June 2019

Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis.

J Allergy Clin Immunol 2019 05 14;143(5):1925-1928.e7. Epub 2019 Jan 14.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2018.12.1004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504611PMC
May 2019

Rhinoviruses and Their Receptors.

Chest 2019 05 17;155(5):1018-1025. Epub 2019 Jan 17.

Department of Pediatrics, University of Wisconsin-Madison, Madison, WI.

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http://dx.doi.org/10.1016/j.chest.2018.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533451PMC
May 2019

Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland.

Pediatr Infect Dis J 2019 03;38(3):e59-e62

From the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1097/INF.0000000000002141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329669PMC
March 2019

Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing.

Allergy 2019 03 8;74(3):518-526. Epub 2018 Oct 8.

Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.

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http://doi.wiley.com/10.1111/all.13593
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http://dx.doi.org/10.1111/all.13593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387855PMC
March 2019

Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort.

PLoS One 2018 27;13(9):e0204708. Epub 2018 Sep 27.

Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204708PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160166PMC
March 2019

TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1.

J Immunol 2018 12 5;201(12):3503-3513. Epub 2018 Nov 5.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390;

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http://dx.doi.org/10.4049/jimmunol.1800881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909928PMC
December 2018

Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.

Cell Host Microbe 2018 09;24(3):341-352.e5

Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; School of BioSciences, The University of Melbourne, Parkville, VIC 3010, Australia; Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC 3010, Australia; The Alan Turing Institute, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291254PMC
September 2018

Glycation of whey protein with dextrans of different molar mass: Effect on immunoglobulin E-binding capacity with blood sera obtained from patients with cow milk protein allergy.

J Dairy Sci 2018 Aug 16;101(8):6823-6834. Epub 2018 May 16.

Department of Food Science, Madison 53706; Center for Dairy Research, University of Wisconsin, Madison 53706. Electronic address:

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http://dx.doi.org/10.3168/jds.2017-14338DOI Listing
August 2018

Reply.

J Allergy Clin Immunol 2018 08 23;142(2):713. Epub 2018 Jun 23.

University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2018.04.035DOI Listing
August 2018

A new model of wheezing severity in young children using the validated ISAAC wheezing module: A latent variable approach with validation in independent cohorts.

PLoS One 2018 17;13(4):e0194739. Epub 2018 Apr 17.

Vanderbilt University Medical Center, Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, T-1218 Medical Center North, Nashville, TN, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194739PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903664PMC
July 2018

Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab.

J Allergy Clin Immunol 2018 05 1;141(5):1735-1743.e9. Epub 2017 Sep 1.

Department of Medicine, Division of Allergy & Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749173135
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http://dx.doi.org/10.1016/j.jaci.2017.07.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013066PMC
May 2018

Farm exposure in early childhood is associated with a lower risk of severe respiratory illnesses.

J Allergy Clin Immunol 2018 01 21;141(1):454-456.e4. Epub 2017 Sep 21.

Marshfield Clinic Research Foundation, National Farm Medicine Center, Marshfield, Wis; Department of Occupational Medicine, Marshfield Clinic, Marshfield, Wis.

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http://dx.doi.org/10.1016/j.jaci.2017.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758418PMC
January 2018

Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma.

Allergy Asthma Immunol Res 2018 Jan;10(1):12-17

Departments of Pediatrics and Medicine, University of Wisconsin-Madison, Madison, WI, USA.

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http://dx.doi.org/10.4168/aair.2018.10.1.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705478PMC
January 2018

Picornavectors. Viruses That Spread Bacteria.

Authors:
James E Gern

Am J Respir Crit Care Med 2017 11;196(9):1095-1096

1 Department of Pediatrics and.

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http://dx.doi.org/10.1164/rccm.201706-1073EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850562PMC
November 2017

Role of viral infections in the development and exacerbation of asthma in children.

J Allergy Clin Immunol 2017 Oct;140(4):895-906

Departments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172811PMC
October 2017

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers.

J Allergy Clin Immunol 2017 Aug 21;140(2):534-542. Epub 2016 Dec 21.

Asthma and Airway Disease Research Center, University of Arizona, Tucson, Ariz; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, Ariz; Arizona Center for the Biology of Complex Diseases, University of Arizona, Tucson, Ariz; Bio5 Institute, University of Arizona, Tucson, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479765PMC
August 2017

Community-acquired rhinovirus infection is associated with changes in the airway microbiome.

J Allergy Clin Immunol 2017 07 19;140(1):312-315.e8. Epub 2017 Mar 19.

Department of Pediatrics, University of Wisconsin-Madison, Madison, Wis; Department of Medicine, University of Wisconsin-Madison, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2017.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496777PMC
July 2017

Rhinovirus C targets ciliated airway epithelial cells.

Respir Res 2017 05 4;18(1):84. Epub 2017 May 4.

Department of Pediatrics, School of Medicine and Public Health, CSC K4/945, 600 Highland Ave, Madison, 53792, WI, USA.

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http://dx.doi.org/10.1186/s12931-017-0567-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418766PMC
May 2017

Relationships among aeroallergen sensitization, peripheral blood eosinophils, and periostin in pediatric asthma development.

J Allergy Clin Immunol 2017 Mar 5;139(3):790-796. Epub 2016 Jul 5.

Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine & Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2016.05.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215990PMC
March 2017

Relationships among Maternal Stress and Depression, Type 2 Responses, and Recurrent Wheezing at Age 3 Years in Low-Income Urban Families.

Am J Respir Crit Care Med 2017 03;195(5):674-681

7 Kravis Children's Hospital and Mindich Child Health & Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1164/rccm.201602-0272OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363974PMC
March 2017

Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence.

J Allergy Clin Immunol 2017 02 10;139(2):501-507. Epub 2016 May 10.

Department of Pediatrics, University of Wisconsin-Madison, Madison, Wis; Department of Medicine, University of Wisconsin-Madison, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2016.03.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104680PMC
February 2017

Assessment of wheezing frequency and viral etiology on childhood and adolescent asthma risk.

J Allergy Clin Immunol 2017 02 5;139(2):692-694. Epub 2016 Sep 5.

Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine & Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2016.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026309PMC
February 2017

Lessons learned from birth cohort studies conducted in diverse environments.

J Allergy Clin Immunol 2017 02;139(2):379-386

Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2016.12.941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508737PMC
February 2017

Rhinovirus species and clinical characteristics in the first wheezing episode in children.

J Med Virol 2016 12 2;88(12):2059-2068. Epub 2016 Jun 2.

Department of Virology, University of Turku, Finland.

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http://dx.doi.org/10.1002/jmv.24587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140033PMC
December 2016

Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells.

Virology 2016 12 13;499:350-360. Epub 2016 Oct 13.

Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.

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http://dx.doi.org/10.1016/j.virol.2016.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110265PMC
December 2016

Respiratory Syncytial Virus Bronchiolitis: Enter the Microbiome.

Authors:
James E Gern

Am J Respir Crit Care Med 2016 11;194(9):1044-1045

1 School of Medicine and Public Health University of Wisconsin-Madison Madison, Wisconsin.

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http://www.atsjournals.org/doi/10.1164/rccm.201605-1018ED
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http://dx.doi.org/10.1164/rccm.201605-1018EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440971PMC
November 2016

Nasopharyngeal microbiota composition of children is related to the frequency of upper respiratory infection and acute sinusitis.

Microbiome 2016 07 1;4(1):34. Epub 2016 Jul 1.

Division of Gastroenterology, Department of Medicine, University of California San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s40168-016-0179-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929776PMC
July 2016

Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics.

J Pediatr 2016 05 11;172:202-204.e1. Epub 2016 Feb 11.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.jpeds.2016.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846467PMC
May 2016

Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in Children Ages 4-7 Years.

J Pediatr 2016 Apr 16;171:133-9.e1. Epub 2016 Jan 16.

Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI.

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http://dx.doi.org/10.1016/j.jpeds.2015.12.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808614PMC
April 2016

Rhinoviruses and Their Receptors: Implications for Allergic Disease.

Curr Allergy Asthma Rep 2016 Apr;16(4):30

Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Ave, Madison, WI, 53792, USA.

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http://dx.doi.org/10.1007/s11882-016-0608-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854667PMC
April 2016

The contributions of allergic sensitization and respiratory pathogens to asthma inception.

J Allergy Clin Immunol 2016 Mar;137(3):659-65; quiz 666

Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.

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http://dx.doi.org/10.1016/j.jaci.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782609PMC
March 2016

Virus/Allergen Interaction in Asthma Exacerbation.

Authors:
James E Gern

Ann Am Thorac Soc 2015 Nov;12 Suppl 2:S137-43

Department of Pediatrics and Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.

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http://dx.doi.org/10.1513/AnnalsATS.201503-153AWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722838PMC
November 2015

Detection of respiratory syncytial virus and rhinovirus in healthy infants.

BMC Res Notes 2015 Nov 25;8:718. Epub 2015 Nov 25.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 125 Nashua Street, Suite 920, Boston, MA, 02114, USA.

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http://www.biomedcentral.com/content/pdf/s13104-015-1695-6.p
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http://www.biomedcentral.com/1756-0500/8/718
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http://dx.doi.org/10.1186/s13104-015-1695-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660840PMC
November 2015