Publications by authors named "James Di Santo"

100Publications

Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria.

Cell 2020 Dec 8;183(7):1826-1847.e31. Epub 2020 Dec 8.

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY 10065, USA; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France; University of Paris, Imagine Institute, 75015 Paris, France; Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, AP-HP, 75015 Paris, France; Howard Hughes Medical Institute, New York, NY, USA. Electronic address:

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December 2020

Editorial: Molecular Strategies Aimed to Boost NK Cell-Based Immunotherapy of Cancer.

Front Immunol 2020 16;11:1132. Epub 2020 Jun 16.

Cancer Research Center of Marseille, INSERM U1068, CNRS U7258, Aix-Marseille University, Institut Paoli-Calmettes, Marseille, France.

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June 2020

Microbiota stimulation generates LCMV-specific memory CD8 T cells in SPF mice and determines their TCR repertoire during LCMV infection.

Mol Immunol 2020 08 17;124:125-141. Epub 2020 Jun 17.

Population Biology Unit, CNRS URA 196, Institut Pasteur, Paris 75015, France; INSERM, U1151, CNRS, UMR8253, Institut Necker Enfants Malades, Université Paris Descartes, Paris 75015, France. Electronic address:

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August 2020

STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice.

Cell Rep 2020 06;31(11):107771

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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June 2020

Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA.

Immunity 2020 04 1;52(4):635-649.e4. Epub 2020 Apr 1.

Laboratory for Intestinal Ecosystem, Center for Integrative Medical Sciences, RIKEN Yokohama, Kanagawa 230-0045, Japan; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University Yokohama, Kanagawa 230-0045, Japan; Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology Ebina, Kanagawa 243-0435, Japan. Electronic address:

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April 2020

Antibody-coated microbiota in nasopharynx of healthy individuals and IVIg-treated patients with hypogammaglobulinemia.

J Allergy Clin Immunol 2020 Jun 16;145(6):1686-1690.e4. Epub 2020 Jan 16.

Innate Immunity Unit, Institut Pasteur, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1223, Paris, France. Electronic address:

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June 2020

Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses and in Humanized Mice.

Antimicrob Agents Chemother 2020 01 27;64(2). Epub 2020 Jan 27.

Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA

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January 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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October 2019

Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples.

J Leukoc Biol 2020 01 4;107(1):27-42. Epub 2019 Aug 4.

IDMIT Department, CEA-Université Paris Sud 11-INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, IBFJ, F-92265, Paris, France.

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January 2020

Editorial overview: Pillars of innate immunity: constantly learning and trying to remember.

Curr Opin Immunol 2019 02;56:iii-vi

Innate Immunity Unit, Institut Pasteur, Inserm U1223, Paris, France.

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February 2019

Modeling Infectious Diseases in Mice with a "Humanized" Immune System.

Microbiol Spectr 2019 03;7(2)

Innate Immunity Unit, Immunology Department, Institut Pasteur, Paris, France.

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March 2019

An Id2-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.

Immunity 2019 04 26;50(4):1054-1068.e3. Epub 2019 Mar 26.

Innate Immunity Unit, Institut Pasteur, Paris 75724, France; Inserm U1223, Institut Pasteur, Paris 75724, France. Electronic address:

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April 2019

The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses.

PLoS Pathog 2018 10 26;14(10):e1007406. Epub 2018 Oct 26.

MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom.

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October 2018

ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time.

Eur J Immunol 2019 01 2;49(1):11-18. Epub 2018 Nov 2.

Innate Immunity Unit, Institut Pasteur, 75724, Paris, France.

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January 2019

Innate Lymphoid Cells: 10 Years On.

Cell 2018 08;174(5):1054-1066

Department of Experimental Immunology Academic Medical Center of the University of Amsterdam, Amsterdam, the Netherlands.

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August 2018

Innate Lymphoid Cell Development: A T Cell Perspective.

Immunity 2018 06;48(6):1091-1103

Innate Immunity Unit, Institut Pasteur, Paris 75015, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1223, Paris 75015, France. Electronic address:

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June 2018

The Yin and Yang of regulatory T cells in immunotherapy.

Oncotarget 2018 Feb 3;9(13):10828-10829. Epub 2018 Feb 3.

James P. Di Santo: Innate Immunity Unit, Institut Pasteur, Paris, France; Inserm, Paris, France.

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February 2018

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade.

J Immunol 2018 02 10;200(4):1389-1398. Epub 2018 Jan 10.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal;

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February 2018

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice.

Blood Adv 2017 Dec 19;1(27):2729-2741. Epub 2017 Dec 19.

Department of Immunology and Microbiology, School of Medicine, University of Colorado Denver, Aurora, CO.

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December 2017

Humanized mouse models to study pathophysiology and treatment of HIV infection.

Curr Opin HIV AIDS 2018 03;13(2):143-151

Innate Immunity Unit, Immunology Department, Institut Pasteur.

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March 2018

Regulatory T cells control toxicity in a humanized model of IL-2 therapy.

Nat Commun 2017 11 24;8(1):1762. Epub 2017 Nov 24.

Institut Pasteur, Innate Immunity Unit, Immunology Department, 75724, Paris, France.

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November 2017

'ILC-poiesis': generating tissue ILCs from naïve precursors.

Oncotarget 2017 Oct 19;8(47):81729-81730. Epub 2017 Sep 19.

James P. Di Santo: Innate Immunity Unit, Institut Pasteur, Inserm U1223, Paris, France.

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October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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October 2017

Animal models for viral diseases: Non-human primate and humanized mouse models for viral infections.

Curr Opin Virol 2017 08;25:v-vii

Center for Vaccine Research, University of Pittsburgh, 9044 BST3, 3501 Fifth Avenue, Pittsburgh, PA 15261, USA. Electronic address:

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August 2017

Modeling Natural Killer Cell Targeted Immunotherapies.

Front Immunol 2017 29;8:370. Epub 2017 Mar 29.

Innate Immunity Unit, Institut Pasteur, Paris, France; Inserm U1223, Paris, France.

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March 2017

Developmental options and functional plasticity of innate lymphoid cells.

Curr Opin Immunol 2017 Feb 28;44:61-68. Epub 2017 Mar 28.

Innate Immunity Unit, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France; INSERM U1223, 75724 Paris, France. Electronic address:

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February 2017

Glomerular common gamma chain confers B- and T-cell-independent protection against glomerulonephritis.

Kidney Int 2017 05 19;91(5):1146-1158. Epub 2017 Jan 19.

Unité Mixte de Recherche (UMR) 1155, Institut National de la Santé et de la Recherche Médicale (Inserm), Paris, France; Sorbonne Universités, Université Pierre et Marie Curie Paris 06, Paris, France; Urgences Néphrologiques et Transplantation Rénale, Hôpital Tenon, Assistance Publique - Hôpitaux de Paris, Paris, France; Weill Cornell Medicine, The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, New York, USA. Electronic address:

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May 2017

Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells.

J Immunol 2016 06 22;196(11):4731-8. Epub 2016 Apr 22.

Unité d'Immunité Innée, Institut Pasteur, 75724 Paris, France; INSERM U1223, 75724 Paris, France;

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June 2016

Notch signaling in group 3 innate lymphoid cells modulates their plasticity.

Sci Signal 2016 05 3;9(426):ra45. Epub 2016 May 3.

Lymphopoiesis Unit, Immunology Department, Institut Pasteur, 75015 Paris, France. Université Paris Diderot, Sorbonne Paris Cité, Cellule Pasteur, 75015 Paris, France. INSERM U1223, 75015 Paris, France.

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May 2016

IL-12 drives functional plasticity of human group 2 innate lymphoid cells.

J Exp Med 2016 Apr 14;213(4):569-83. Epub 2016 Mar 14.

Innate Immunity Unit, Institut Pasteur, 75724 Paris, France Institut National de la Santé et de la Recherche Médicale (INSERM) U1223, 75015 Paris, France

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April 2016

An Intestinal Inflammasome - The ILC3-Cytokine Tango.

Trends Mol Med 2016 Apr 7;22(4):269-271. Epub 2016 Mar 7.

Innate Immunity Unit, Institut Pasteur, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1223, Paris, France.

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April 2016

Probing Human NK Cell Biology Using Human Immune System (HIS) Mice.

Curr Top Microbiol Immunol 2016 ;395:191-208

Innate Immunity Unit, Institut Pasteur, 25 rue du Docteur Roux, Paris, 75724, France.

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June 2016

IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.

Eur J Immunol 2015 Dec 2;45(12):3324-38. Epub 2015 Nov 2.

Cytokines and Adaptive Immunity Laboratory, CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.

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December 2015

Transcriptional regulation of innate lymphoid cell fate.

Nat Rev Immunol 2015 Jul 12;15(7):415-28. Epub 2015 Jun 12.

Innate Immunity Unit, Institut Pasteur, Paris 75015, and the Institut National de la Santé et de la Recherche Médicale (INSERM) U668, Paris 75015, France.

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July 2015

Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology.

Science 2015 May 21;348(6237):aaa6566. Epub 2015 May 21.

Medical Research Council (MRC) Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

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May 2015

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

PLoS One 2015 17;10(3):e0119820. Epub 2015 Mar 17.

Innate Immunity Unit, Department of Immunology, Institut Pasteur, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U668, Paris, France.

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March 2016

Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping.

Clin Immunol 2015 Apr 6;157(2):261-76. Epub 2015 Jan 6.

Center for Human Immunology, Institut Pasteur, Paris, France; Laboratory of Immunoregulation, Department of Immunology, Institut Pasteur, Paris, France. Electronic address:

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April 2015

A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice.

Blood 2015 Feb 18;125(9):1427-34. Epub 2014 Dec 18.

Laboratory of Normal and Pathological Homeostasis of the Immune System, INSERM Unité Mixte de Recherche 1163, Paris France; Imagine Institute, Paris Descartes University-Sorbonne Paris Cité, Paris France; Centre d'Etudes des Déficits Immunitaires, Assistance Publique-Hôpitaux de Paris, Hôpital Necker, Paris, France.

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February 2015

The brave new world of innate lymphoid cells.

Nat Immunol 2015 Jan;16(1):1-5

Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, Inserm U1104, CNRS UMR7280, Marseille, France, and the Assistance Publique-Hôpitaux de Marseille, Marseille, France.

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January 2015

The chemokine receptor CXCR6 controls the functional topography of interleukin-22 producing intestinal innate lymphoid cells.

Immunity 2014 Nov 6;41(5):776-88. Epub 2014 Nov 6.

Innate Immunity Unit, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France; Inserm U668, 75724 Paris, France. Electronic address:

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November 2014

Engineering attenuated virulence of a Theileria annulata-infected macrophage.

PLoS Negl Trop Dis 2014 6;8(11):e3183. Epub 2014 Nov 6.

Laboratoire de Biologie Cellulaire Comparative des Apicomplexes, Faculté de Médicine, Université Paris Descartes - Sorbonne Paris Cité, Paris, France; Inserm U1016, Cnrs UMR8104, Cochin Institute, Paris, France.

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May 2016

GATA-3 function in innate and adaptive immunity.

Immunity 2014 Aug;41(2):191-206

Department of Pulmonary Medicine, Erasmus MC, 3000 CA Rotterdam, the Netherlands. Electronic address:

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August 2014

Conditional ablation of NKp46+ cells using a novel Ncr1(greenCre) mouse strain: NK cells are essential for protection against pulmonary B16 metastases.

Eur J Immunol 2014 Nov 19;44(11):3380-91. Epub 2014 Sep 19.

Département d'Immunologie, Unité d'Immunité Innée, Institut Pasteur, Paris, France; Institut Pasteur, INSERM U668, Paris, France; Cellule Pasteur, Sorbonne Paris Cité, Univ. Paris Diderot, Paris, France.

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November 2014

Staying innate: transcription factor maintenance of innate lymphoid cell identity.

Authors:
James P Di Santo

Immunol Rev 2014 Sep;261(1):169-76

Innate Immunity Unit, Institut Pasteur, Paris, France; Inserm U668, Institut Pasteur, Paris, France.

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September 2014

Innate lymphoid cells: of precursors and products….

Curr Biol 2014 Jun;24(12):R573-R576

Innate Immunity Unit, Institut Pasteur, Paris, France; INSERM U668, Paris, France. Electronic address:

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June 2014

Gata3 drives development of RORγt+ group 3 innate lymphoid cells.

J Exp Med 2014 Feb 13;211(2):199-208. Epub 2014 Jan 13.

Innate Immunity Unit, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France.

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February 2014

Taming the beast within: regulation of innate lymphoid cell homeostasis and function.

J Immunol 2013 Nov;191(9):4489-96

Innate Immunity Unit, Institut Pasteur, 75724 Paris, France.

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November 2013

Neutrophils mediate antibody-induced antitumor effects in mice.

Blood 2013 Oct 26;122(18):3160-4. Epub 2013 Aug 26.

Département d'Immunologie, Laboratoire Anticorps en Thérapie et Pathologie, Institut Pasteur, Paris, France;

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October 2013

The Rag2⁻Il2rb⁻Dmd⁻ mouse: a novel dystrophic and immunodeficient model to assess innovating therapeutic strategies for muscular dystrophies.

Mol Ther 2013 Oct 23;21(10):1950-7. Epub 2013 Aug 23.

1] UPMC Université Pierre et Marie Curie (UPMC), UM76, Institut de Myologie, Paris, France [2] INSERM U 974, Institut de Myologie, Paris, France [3] CNRS UMR 7215, Institut de Myologie, Paris, France [4] Department of Biology, University of Padova, Padova, Italy.

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October 2013

Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo.

J Immunol 2013 Aug 21;191(3):1200-9. Epub 2013 Jun 21.

Infection and Immunity Unit, CAGE Laboratory, Institute for Molecular and Cellular Biology, University of Porto, 4150-180 Porto, Portugal.

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August 2013

Developmental programming of natural killer and innate lymphoid cells.

Curr Opin Immunol 2013 Apr 13;25(2):130-8. Epub 2013 Mar 13.

Unité d'Immunité Innée, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, France.

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April 2013

Innate lymphoid cells--a proposal for uniform nomenclature.

Nat Rev Immunol 2013 Feb;13(2):145-9

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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February 2013

Thymocytes may persist and differentiate without any input from bone marrow progenitors.

J Exp Med 2012 Jul 9;209(8):1401-8. Epub 2012 Jul 9.

Institut National de la Santé et de la Recherche Médicale, Unit 1020, 75015 Paris, France.

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July 2012

Slowing down differentiation of engrafted human myoblasts into immunodeficient mice correlates with increased proliferation and migration.

Mol Ther 2012 Jan 20;20(1):146-54. Epub 2011 Sep 20.

Thérapie des maladies du muscle strié/Institut de Myologie UM76, Université Pierre et Marie Curie, INSERM-U974; CNRS-UMR7215, Paris, France.

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January 2012

Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation.

J Immunol 2011 Sep 1;187(5):2084-8. Epub 2011 Aug 1.

Institut Pasteur, Dynamics of Immune Responses Unit, F-75015 Paris, France.

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September 2011

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Proc Natl Acad Sci U S A 2011 Aug 25;108(32):13224-9. Epub 2011 Jul 25.

Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam, Center for Immunology Amsterdam, 1105AZ Amsterdam, The Netherlands.

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August 2011

CD4+ T cells are not essential for control of early acute Cryptosporidium parvum infection in neonatal mice.

Infect Immun 2011 Apr 31;79(4):1647-53. Epub 2011 Jan 31.

Barts and the London School of Medicine and Dentistry, Centre for Digestive Diseases, Blizard Institute of Cell and Molecular Science, Queen Mary University of London, London, UK.

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April 2011

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

Nat Immunol 2011 Jan 28;12(1):21-7. Epub 2010 Nov 28.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, Amsterdam, The Netherlands.

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January 2011