James D Brenton

James D Brenton

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James D Brenton

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Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women.

Cancer Med 2019 Apr 18. Epub 2019 Apr 18.

Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.1996
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http://dx.doi.org/10.1002/cam4.1996DOI Listing
April 2019

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk.

Authors:
Yaohua Yang Lang Wu Xiang Shu Yingchang Lu Xiao-Ou Shu Qiuyin Cai Alicia Beeghly-Fadiel Bingshan Li Fei Ye Andrew Berchuck Hoda Anton-Culver Susana Banerjee Javier Benitez Line Bjørge James D Brenton Ralf Butzow Ian G Campbell Jenny Chang-Claude Kexin Chen Linda S Cook Daniel W Cramer Anna deFazio Joe Dennis Jennifer A Doherty Thilo Dörk Diana M Eccles Digna Velez Edwards Peter A Fasching Renée T Fortner Simon A Gayther Graham G Giles Rosalind M Glasspool Ellen L Goode Marc T Goodman Jacek Gronwald Holly R Harris Florian Heitz Michelle A Hildebrandt Estrid Høgdall Claus K Høgdall David G Huntsman Siddhartha P Kar Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Anita Koushik Diether Lambrechts Nhu D Le Douglas A Levine Leon F Massuger Keitaro Matsuo Taymaa May Iain A McNeish Usha Menon Francesmary Modugno Alvaro N Monteiro Patricia G Moorman Kirsten B Moysich Roberta B Ness Heli Nevanlinna Håkan Olsson N Charlotte Onland-Moret Sue K Park James Paul Celeste L Pearce Tanja Pejovic Catherine M Phelan Malcolm C Pike Susan J Ramus Elio Riboli Cristina Rodriguez-Antona Isabelle Romieu Dale P Sandler Joellen M Schildkraut Veronica W Setiawan Kang Shan Nadeem Siddiqui Weiva Sieh Meir J Stampfer Rebecca Sutphen Anthony J Swerdlow Lukasz M Szafron Soo Hwang Teo Shelley S Tworoger Jonathan P Tyrer Penelope M Webb Nicolas Wentzensen Emily White Walter C Willett Alicja Wolk Yin Ling Woo Anna H Wu Li Yan Drakoulis Yannoukakos Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2019 02 17;79(3):505-517. Epub 2018 Dec 17.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359948PMC
February 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients.

J Mol Diagn 2018 Nov 28;20(6):883-892. Epub 2018 Aug 28.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, University of Cambridge, Cambridge, United Kingdom; Cancer Research UK Major Centre, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197164PMC
November 2018

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.

Authors:
Peter F Rambau Robert A Vierkant Maria P Intermaggio Linda E Kelemen Marc T Goodman Esther Herpel Paul D Pharoah Stefan Kommoss Mercedes Jimenez-Linan Beth Y Karlan Aleksandra Gentry-Maharaj Usha Menon Susanna Hernando Polo Francisco J Candido Dos Reis Jennifer Anne Doherty Simon A Gayther Raghwa Sharma Melissa C Larson Paul R Harnett Emma Hatfield Jurandyr M de Andrade Gregg S Nelson Helen Steed Joellen M Schildkraut Micheal E Carney Estrid Høgdall Alice S Whittemore Martin Widschwendter Catherine J Kennedy Frances Wang Qin Wang Chen Wang Sebastian M Armasu Frances Daley Penny Coulson Micheal E Jones Micheal S Anglesio Christine Chow Anna de Fazio Montserrat García-Closas Sara Y Brucker Cezary Cybulski Holly R Harris Andreas D Hartkopf Tomasz Huzarski Allan Jensen Jan Lubiński Oleg Oszurek Javier Benitez Fady Mina Annette Staebler Florin Andrei Taran Jana Pasternak Aline Talhouk Mary Anne Rossing Joy Hendley Robert P Edwards Sian Fereday Francesmary Modugno Roberta B Ness Weiva Sieh Mona A El-Bahrawy Stacey J Winham Jenny Lester Susanne K Kjaer Jacek Gronwald Peter Sinn Peter A Fasching Jenny Chang-Claude Kirsten B Moysich David D Bowtell Brenda Y Hernandez Hugh Luk Sabine Behrens Mitul Shah Audrey Jung Prafull Ghatage Jennifer Alsop Kathryn Alsop Jesús García-Donas Pamela J Thompson Anthony J Swerdlow Chloe Karpinskyj Alicia Cazorla-Jiménez María J García Susha Deen Lynne R Wilkens José Palacios Andrew Berchuck Jennifer M Koziak James D Brenton Linda S Cook Ellen L Goode David G Huntsman Susan J Ramus Martin Köbel

J Pathol Clin Res 2018 Oct 21;4(4):250-261. Epub 2018 Sep 21.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1002/cjp2.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174617PMC
October 2018

You won't believe this old test … that does cheap single-cell mutation detection.

J Pathol Clin Res 2018 07;4(3):149-153

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/cjp2.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065114PMC
July 2018

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer.

Mayo Clin Proc 2018 03;93(3):307-320

Department of Health Sciences Research, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870793PMC
March 2018

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

Authors:
Ellen L Goode Matthew S Block Kimberly R Kalli Robert A Vierkant Wenqian Chen Zachary C Fogarty Aleksandra Gentry-Maharaj Aleksandra Tołoczko Alexander Hein Aliecia L Bouligny Allan Jensen Ana Osorio Andreas Hartkopf Andy Ryan Anita Chudecka-Głaz Anthony M Magliocco Arndt Hartmann Audrey Y Jung Bo Gao Brenda Y Hernandez Brooke L Fridley Bryan M McCauley Catherine J Kennedy Chen Wang Chloe Karpinskyj Christiani B de Sousa Daniel G Tiezzi David L Wachter Esther Herpel Florin Andrei Taran Francesmary Modugno Gregg Nelson Jan Lubiński Janusz Menkiszak Jennifer Alsop Jenny Lester Jesús García-Donas Jill Nation Jillian Hung José Palacios Joseph H Rothstein Joseph L Kelley Jurandyr M de Andrade Luis Robles-Díaz Maria P Intermaggio Martin Widschwendter Matthias W Beckmann Matthias Ruebner Mercedes Jimenez-Linan Naveena Singh Oleg Oszurek Paul R Harnett Peter F Rambau Peter Sinn Philipp Wagner Prafull Ghatage Raghwa Sharma Robert P Edwards Roberta B Ness Sandra Orsulic Sara Y Brucker Sharon E Johnatty Teri A Longacre Eilber Ursula Valerie McGuire Weiva Sieh Yanina Natanzon Zheng Li Alice S Whittemore deFazio Anna Annette Staebler Beth Y Karlan Blake Gilks David D Bowtell Estrid Høgdall Francisco J Candido dos Reis Helen Steed Ian G Campbell Jacek Gronwald Javier Benítez Jennifer M Koziak Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman María José García Peter A Fasching Stefan Kommoss Suha Deen Susanne K Kjaer Usha Menon James D Brenton Paul DP Pharoah Georgia Chenevix-Trench David G Huntsman Stacey J Winham Martin Köbel Susan J Ramus

JAMA Oncol 2017 12;3(12):e173290

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia

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http://dx.doi.org/10.1001/jamaoncol.2017.3290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744673PMC
December 2017

Association between tumour infiltrating lymphocytes, histotype and clinical outcome in epithelial ovarian cancer.

BMC Cancer 2017 Sep 20;17(1):657. Epub 2017 Sep 20.

Department of Pathology, CRUK Cambridge Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1186/s12885-017-3585-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607562PMC
September 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Authors:
Catherine M Phelan Karoline B Kuchenbaecker Jonathan P Tyrer Siddhartha P Kar Kate Lawrenson Stacey J Winham Joe Dennis Ailith Pirie Marjorie J Riggan Ganna Chornokur Madalene A Earp Paulo C Lyra Janet M Lee Simon Coetzee Jonathan Beesley Lesley McGuffog Penny Soucy Ed Dicks Andrew Lee Daniel Barrowdale Julie Lecarpentier Goska Leslie Cora M Aalfs Katja K H Aben Marcia Adams Julian Adlard Irene L Andrulis Hoda Anton-Culver Natalia Antonenkova Gerasimos Aravantinos Norbert Arnold Banu K Arun Brita Arver Jacopo Azzollini Judith Balmaña Susana N Banerjee Laure Barjhoux Rosa B Barkardottir Yukie Bean Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Marcus Q Bernardini Michael J Birrer Line Bjorge Amanda Black Kenneth Blankstein Marinus J Blok Clara Bodelon Natalia Bogdanova Anders Bojesen Bernardo Bonanni Åke Borg Angela R Bradbury James D Brenton Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Fiona Bruinsma Joan Brunet Bruno Buecher Ralf Butzow Saundra S Buys Trinidad Caldes Maria A Caligo Ian Campbell Rikki Cannioto Michael E Carney Terence Cescon Salina B Chan Jenny Chang-Claude Stephen Chanock Xiao Qing Chen Yoke-Eng Chiew Jocelyne Chiquette Wendy K Chung Kathleen B M Claes Thomas Conner Linda S Cook Jackie Cook Daniel W Cramer Julie M Cunningham Aimee A D'Aloisio Mary B Daly Francesca Damiola Sakaeva Dina Damirovna Agnieszka Dansonka-Mieszkowska Fanny Dao Rosemarie Davidson Anna DeFazio Capucine Delnatte Kimberly F Doheny Orland Diez Yuan Chun Ding Jennifer Anne Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Laure Dossus Mercedes Duran Matthias Dürst Bernd Dworniczak Diana Eccles Todd Edwards Ros Eeles Ursula Eilber Bent Ejlertsen Arif B Ekici Steve Ellis Mingajeva Elvira Kevin H Eng Christoph Engel D Gareth Evans Peter A Fasching Sarah Ferguson Sandra Fert Ferrer James M Flanagan Zachary C Fogarty Renée T Fortner Florentia Fostira William D Foulkes George Fountzilas Brooke L Fridley Tara M Friebel Eitan Friedman Debra Frost Patricia A Ganz Judy Garber María J García Vanesa Garcia-Barberan Andrea Gehrig Aleksandra Gentry-Maharaj Anne-Marie Gerdes Graham G Giles Rosalind Glasspool Gord Glendon Andrew K Godwin David E Goldgar Teodora Goranova Martin Gore Mark H Greene Jacek Gronwald Stephen Gruber Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Thomas V O Hansen Patricia A Harrington Holly R Harris Jan Hauke Alexander Hein Alex Henderson Michelle A T Hildebrandt Peter Hillemanns Shirley Hodgson Claus K Høgdall Estrid Høgdall Frans B L Hogervorst Helene Holland Maartje J Hooning Karen Hosking Ruea-Yea Huang Peter J Hulick Jillian Hung David J Hunter David G Huntsman Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Edwin S Iversen Louise Izatt Angel Izquierdo Anna Jakubowska Paul James Ramunas Janavicius Mats Jernetz Allan Jensen Uffe Birk Jensen Esther M John Sharon Johnatty Michael E Jones Päivi Kannisto Beth Y Karlan Anthony Karnezis Karin Kast Catherine J Kennedy Elza Khusnutdinova Lambertus A Kiemeney Johanna I Kiiski Sung-Won Kim Susanne K Kjaer Martin Köbel Reidun K Kopperud Torben A Kruse Jolanta Kupryjanczyk Ava Kwong Yael Laitman Diether Lambrechts Nerea Larrañaga Melissa C Larson Conxi Lazaro Nhu D Le Loic Le Marchand Jong Won Lee Shashikant B Lele Arto Leminen Dominique Leroux Jenny Lester Fabienne Lesueur Douglas A Levine Dong Liang Clemens Liebrich Jenna Lilyquist Loren Lipworth Jolanta Lissowska Karen H Lu Jan Lubinński Craig Luccarini Lene Lundvall Phuong L Mai Gustavo Mendoza-Fandiño Siranoush Manoukian Leon F A G Massuger Taymaa May Sylvie Mazoyer Jessica N McAlpine Valerie McGuire John R McLaughlin Iain McNeish Hanne Meijers-Heijboer Alfons Meindl Usha Menon Arjen R Mensenkamp Melissa A Merritt Roger L Milne Gillian Mitchell Francesmary Modugno Joanna Moes-Sosnowska Melissa Moffitt Marco Montagna Kirsten B Moysich Anna Marie Mulligan Jacob Musinsky Katherine L Nathanson Lotte Nedergaard Roberta B Ness Susan L Neuhausen Heli Nevanlinna Dieter Niederacher Robert L Nussbaum Kunle Odunsi Edith Olah Olufunmilayo I Olopade Håkan Olsson Curtis Olswold David M O'Malley Kai-Ren Ong N Charlotte Onland-Moret Nicholas Orr Sandra Orsulic Ana Osorio Domenico Palli Laura Papi Tjoung-Won Park-Simon James Paul Celeste L Pearce Inge Søkilde Pedersen Petra H M Peeters Bernard Peissel Ana Peixoto Tanja Pejovic Liisa M Pelttari Jennifer B Permuth Paolo Peterlongo Lidia Pezzani Georg Pfeiler Kelly-Anne Phillips Marion Piedmonte Malcolm C Pike Anna M Piskorz Samantha R Poblete Timea Pocza Elizabeth M Poole Bruce Poppe Mary E Porteous Fabienne Prieur Darya Prokofyeva Elizabeth Pugh Miquel Angel Pujana Pascal Pujol Paolo Radice Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Kerstin Rhiem Patricia Rice Andrea Richardson Mark Robson Gustavo C Rodriguez Cristina Rodríguez-Antona Jane Romm Matti A Rookus Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Helga B Salvesen Dale P Sandler Minouk J Schoemaker Leigha Senter V Wendy Setiawan Gianluca Severi Priyanka Sharma Tameka Shelford Nadeem Siddiqui Lucy E Side Weiva Sieh Christian F Singer Hagay Sobol Honglin Song Melissa C Southey Amanda B Spurdle Zsofia Stadler Doris Steinemann Dominique Stoppa-Lyonnet Lara E Sucheston-Campbell Grzegorz Sukiennicki Rebecca Sutphen Christian Sutter Anthony J Swerdlow Csilla I Szabo Lukasz Szafron Yen Y Tan Jack A Taylor Muy-Kheng Tea Manuel R Teixeira Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Liv Cecilie Vestrheim Thomsen Darcy L Thull Laima Tihomirova Anna V Tinker Marc Tischkowitz Silvia Tognazzo Amanda Ewart Toland Alicia Tone Britton Trabert Ruth C Travis Antonia Trichopoulou Nadine Tung Shelley S Tworoger Anne M van Altena David Van Den Berg Annemarie H van der Hout Rob B van der Luijt Mattias Van Heetvelde Els Van Nieuwenhuysen Elizabeth J van Rensburg Adriaan Vanderstichele Raymonda Varon-Mateeva Ana Vega Digna Velez Edwards Ignace Vergote Robert A Vierkant Joseph Vijai Athanassios Vratimos Lisa Walker Christine Walsh Dorothea Wand Shan Wang-Gohrke Barbara Wappenschmidt Penelope M Webb Clarice R Weinberg Jeffrey N Weitzel Nicolas Wentzensen Alice S Whittemore Juul T Wijnen Lynne R Wilkens Alicja Wolk Michelle Woo Xifeng Wu Anna H Wu Hannah Yang Drakoulis Yannoukakos Argyrios Ziogas Kristin K Zorn Steven A Narod Douglas F Easton Christopher I Amos Joellen M Schildkraut Susan J Ramus Laura Ottini Marc T Goodman Sue K Park Linda E Kelemen Harvey A Risch Mads Thomassen Kenneth Offit Jacques Simard Rita Katharina Schmutzler Dennis Hazelett Alvaro N Monteiro Fergus J Couch Andrew Berchuck Georgia Chenevix-Trench Ellen L Goode Thomas A Sellers Simon A Gayther Antonis C Antoniou Paul D P Pharoah

Nat Genet 2017 May 27;49(5):680-691. Epub 2017 Mar 27.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612337PMC
May 2017

Liquid biopsies come of age: towards implementation of circulating tumour DNA.

Nat Rev Cancer 2017 04 24;17(4):223-238. Epub 2017 Feb 24.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1038/nrc.2017.7DOI Listing
April 2017

Optimized p53 immunohistochemistry is an accurate predictor of mutation in ovarian carcinoma.

J Pathol Clin Res 2016 Oct 13;2(4):247-258. Epub 2016 Jul 13.

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre Cambridge CB2 0RE UK.

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http://dx.doi.org/10.1002/cjp2.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091634PMC
October 2016

Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence.

J Struct Biol 2016 09 21;195(3):273-281. Epub 2016 Jun 21.

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.jsb.2016.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991853PMC
September 2016

Sequencing Structural Variants in Cancer for Precision Therapeutics.

Trends Genet 2016 09 29;32(9):530-542. Epub 2016 Jul 29.

Cancer Research UK Cambridge Institute, University of Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2016.07.002DOI Listing
September 2016

Intensive cisplatin/oral etoposide for epithelial ovarian cancer: the Cambridge Gynae-Oncology Centre experience: too toxic for relapse?

Anticancer Drugs 2016 Mar;27(3):239-44

aDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust bCancer Research UK Cambridge Institute cDepartment of Oncology, Hutchison/MRC Research Centre, University of Cambridge dNIHR Cambridge Biomedical Research Centre, Cambridge, UK eUniversity of Melbourne, Shepparton, Victoria, Australia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CAD.0000000000000320DOI Listing
March 2016

Molecular pathogenesis of ovarian clear cell carcinoma.

Future Oncol 2015 ;11(9):1389-405

Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK.

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http://dx.doi.org/10.2217/fon.15.45DOI Listing
February 2016

Models of endometriosis and their utility in studying progression to ovarian clear cell carcinoma.

J Pathol 2016 Jan;238(2):185-96

Department of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital, Cambridge, UK.

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http://dx.doi.org/10.1002/path.4657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855629PMC
January 2016

A Bayesian adaptive design for biomarker trials with linked treatments.

Br J Cancer 2015 Sep 11;113(5):699-705. Epub 2015 Aug 11.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge, UK.

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http://dx.doi.org/10.1038/bjc.2015.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559835PMC
September 2015

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer.

Clin Cancer Res 2015 Feb 14;21(3):652-7. Epub 2014 Nov 14.

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

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http://clincancerres.aacrjournals.org/content/early/2015/01/
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http://clincancerres.aacrjournals.org/content/21/3/652.full.
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-2497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338615PMC
February 2015

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.

PLoS Med 2015 Feb 24;12(2):e1001789. Epub 2015 Feb 24.

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom; Department of Oncology, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339382PMC
February 2015

Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women.

PLoS One 2014 8;9(5):e96542. Epub 2014 May 8.

Alberta Health Services, Edmonton, Alberta, Canada; Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096542PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014514PMC
January 2015

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

Mol Oncol 2015 Jan 8;9(1):115-27. Epub 2014 Aug 8.

Cancer Research UK, Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Department of Oncology, University of Cambridge, Hills Road, Cambridge CB2 2XZ, UK; Cambridge Experimental Cancer Medicine Centre, Cambridge CB2 0RE, UK; Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 2QQ, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286124PMC
January 2015

Repeatability of quantitative FDG-PET/CT and contrast-enhanced CT in recurrent ovarian carcinoma: test-retest measurements for tumor FDG uptake, diameter, and volume.

Clin Cancer Res 2014 May 26;20(10):2751-60. Epub 2014 Feb 26.

Authors' Affiliations: Department of Radiology, St. Bartholomew's Hospital/Barts Health NHS Trust; Department of Medical Oncology, St Bartholomew's Hospital/Barts Health NHS Trust; Department of Nuclear Medicine, Barts Cancer Institute; Centre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London; Departments of Oncology and Radiology, Cambridge University Hospitals Foundation Trust; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre; NIHR Cambridge Biomedical Research Centre; and Cambridge Experimental Cancer Medicine Centre, Cambridge, United Kingdom; Merck and Co, Whitehouse Station; Sanofi, Bridgewater, New Jersey; and Merck Imaging, West Point, PennsylvaniaAuthors' Affiliations: Department of Radiology, St. Bartholomew's Hospital/Barts Health NHS Trust; Department of Medical Oncology, St Bartholomew's Hospital/Barts Health NHS Trust; Department of Nuclear Medicine, Barts Cancer Institute; Centre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London; Departments of Oncology and Radiology, Cambridge University Hospitals Foundation Trust; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre; NIHR Cambridge Biomedical Research Centre; and Cambridge Experimental Cancer Medicine Centre, Cambridge, United Kingdom; Merck and Co, Whitehouse Station; Sanofi, Bridgewater, New Jersey; and Merck Imaging, West Point, PennsylvaniaAuthors' Affiliations: Department of Radiology, St. Bartholomew's Hospital/Barts Health NHS Trust; Department of Medical Oncology, St Bartholomew's Hospital/Barts Health NHS Trust; Department of Nuclear Medicine, Barts Cancer Institute; Centre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London; Departments of Oncology and Radiology, Cambridge University Hospitals Foundation Trust; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre; NIHR Cambridge

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152730PMC
May 2014

Phylogenetic quantification of intra-tumour heterogeneity.

PLoS Comput Biol 2014 Apr 17;10(4):e1003535. Epub 2014 Apr 17.

University of Cambridge, Cambridge, United Kingdom; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990475PMC
April 2014

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.

Lancet Oncol 2013 Aug 9;14(9):853-62. Epub 2013 Jul 9.

Division of Epidemiology, Department of Health Research and Policy, Stanford University, Stanford, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006367PMC
August 2013

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling.

Dev Biol 2013 Jul 13;379(1):16-27. Epub 2012 Dec 13.

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.ydbio.2012.11.010DOI Listing
July 2013

A metadata-aware application for remote scoring and exchange of tissue microarray images.

BMC Bioinformatics 2013 May 1;14:147. Epub 2013 May 1.

Department of Oncology, University of Cambridge and Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, CB2 0RE, UK.

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http://dx.doi.org/10.1186/1471-2105-14-147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659093PMC
May 2013

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

Authors:
Paul D P Pharoah Ya-Yu Tsai Susan J Ramus Catherine M Phelan Ellen L Goode Kate Lawrenson Melissa Buckley Brooke L Fridley Jonathan P Tyrer Howard Shen Rachel Weber Rod Karevan Melissa C Larson Honglin Song Daniel C Tessier François Bacot Daniel Vincent Julie M Cunningham Joe Dennis Ed Dicks Katja K Aben Hoda Anton-Culver Natalia Antonenkova Sebastian M Armasu Laura Baglietto Elisa V Bandera Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova James D Brenton Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Ian Campbell Michael E Carney Renato S Carvalho Jenny Chang-Claude Y Anne Chen Zhihua Chen Wong-Ho Chow Mine S Cicek Gerhard Coetzee Linda S Cook Daniel W Cramer Cezary Cybulski Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David Fenstermacher James Flanagan Yu-Tang Gao Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham Giles Anxhela Gjyshi Martin Gore Jacek Gronwald Qi Guo Mari K Halle Philipp Harter Alexander Hein Florian Heitz Peter Hillemanns Maureen Hoatlin Estrid Høgdall Claus K Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Kimberly R Kalli Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne Krüger Kjaer Gottfried E Konecny Camilla Krakstad Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Nathan Lee Janet Lee Arto Leminen Boon Kiong Lim Jolanta Lissowska Jan Lubiński Lene Lundvall Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara Olson Irene Orlow James Paul Tanja Pejovic Liisa M Pelttari Jenny Permuth-Wey Malcolm C Pike Elizabeth M Poole Xiaotao Qu Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Hui Shen Vijayalakshmi Shridhar Xiao-Ou Shu Weiva Sieh Melissa C Southey Paul Spellman Kazuo Tajima Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Shelley S Tworoger Anne M van Altena David van den Berg Ignace Vergote Robert A Vierkant Allison F Vitonis Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Boris Winterhoff Yin Ling Woo Anna H Wu Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Marc T Goodman Per Hall Douglas F Easton Celeste L Pearce Andrew Berchuck Georgia Chenevix-Trench Edwin Iversen Alvaro N A Monteiro Simon A Gayther Joellen M Schildkraut Thomas A Sellers

Nat Genet 2013 Apr;45(4):362-70, 370e1-2

The Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.2564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693183PMC
April 2013

Stem cells: Anatomy of an ovarian cancer.

Nature 2013 Mar 6;495(7440):183-4. Epub 2013 Mar 6.

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March 2013

Prolonged response of relapsed high grade serous ovarian carcinoma to the oral angiokinase inhibitor nintedanib in a patient with a germline mutation.

Gynecol Oncol Case Rep 2013 Jan;3

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.

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January 2013

Complex stiffness gradient substrates for studying mechanotactic cell migration.

Adv Mater 2012 Nov 18;24(45):6059-64. Epub 2012 Sep 18.

Biological and Soft Systems, Cavendish Laboratory, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/adma.201202520DOI Listing
November 2012

ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.

Mol Cancer 2012 May 28;11:36. Epub 2012 May 28.

Cancer Research UK, Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, United Kingdom.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-11-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442987PMC
May 2012

The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer.

J Pathol 2012 Apr 9;226(5):703-12. Epub 2012 Feb 9.

Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.

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http://dx.doi.org/10.1002/path.3980DOI Listing
April 2012

Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1.

Bioorg Med Chem 2012 Mar 18;20(5):1749-59. Epub 2012 Jan 18.

Department of Chemistry, Lensfield Road, University of Cambridge, Cambridge, United Kingdom.

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March 2012

A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles.

ACS Med Chem Lett 2012 Mar 19;3(3):177-81. Epub 2012 Jan 19.

Functional Genomics of Ovarian Cancer Laboratory, Cancer Research U.K., Cambridge Research Institute , Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, U.K.

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http://dx.doi.org/10.1021/ml200149gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025774PMC
March 2012

Evolution of platinum resistance in high-grade serous ovarian cancer.

Lancet Oncol 2011 Nov;12(12):1169-74

Cancer Research UK Cambridge Research Institute, Cambridge, UK.

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http://dx.doi.org/10.1016/S1470-2045(11)70123-1DOI Listing
November 2011

Ovarian clear cell carcinoma--bad endometriosis or bad endometrium?

J Pathol 2011 Oct;225(2):157-60

Functional Genomics of Ovarian Cancer Laboratory, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1002/path.2970DOI Listing
October 2011

Two novel determinants of etoposide resistance in small cell lung cancer.

Cancer Res 2011 Jul 3;71(14):4877-87. Epub 2011 Jun 3.

Cancer Research UK Cambridge Research Institute; Department of Oncology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145147PMC
July 2011

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression.

Gut 2011 Apr 10;60(4):499-508. Epub 2010 Nov 10.

Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1136/gut.2010.223602DOI Listing
April 2011

Total syntheses of subereamollines A and B.

Org Biomol Chem 2011 Jan 15;9(1):62-5. Epub 2010 Oct 15.

Department of Chemistry, Lensfield Road, University of Cambridge, Cambridge, United Kingdom CB2 1EW.

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January 2011

Slingshot: a PiggyBac based transposon system for tamoxifen-inducible 'self-inactivating' insertional mutagenesis.

Nucleic Acids Res 2010 Oct 5;38(18):e173. Epub 2010 Aug 5.

Experimental Cancer Genetics, Welcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1093/nar/gkq658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952874PMC
October 2010

Tissue banking of diagnostic lung cancer biopsies for extraction of high quality RNA.

J Thorac Oncol 2010 Jul;5(7):956-63

Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.

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http://dx.doi.org/10.1097/JTO.0b013e3181ddbbe9DOI Listing
July 2010

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

J Pathol 2010 May;221(1):49-56

Functional Genomics of Ovarian Cancer Laboratory, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.

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http://dx.doi.org/10.1002/path.2696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262968PMC
May 2010

The pitfalls of platform comparison: DNA copy number array technologies assessed.

BMC Genomics 2009 Dec 8;10:588. Epub 2009 Dec 8.

Department of Oncology, University of Cambridge, Addenbrooke's Hopsital, Hills Road, Cambridge CB20XZ, UK.

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http://dx.doi.org/10.1186/1471-2164-10-588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797821PMC
December 2009

A metadata approach for clinical data management in translational genomics studies in breast cancer.

BMC Med Genomics 2009 Nov 30;2:66. Epub 2009 Nov 30.

Department of Oncology, University of Cambridge and Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge CB20RE, UK.

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http://dx.doi.org/10.1186/1755-8794-2-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225860PMC
November 2009

Metabolic characterization of primary and metastatic ovarian cancer by 1H-MRS in vivo at 3T.

Magn Reson Med 2009 Oct;62(4):855-61

Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.

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http://dx.doi.org/10.1002/mrm.22067DOI Listing
October 2009

Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.

Breast Cancer Res 2008 31;10(5):214. Epub 2008 Oct 31.

Translational Cancer Therapeutics Laboratory, Cancer Research UK London Research Institute, London, UK.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr2159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614525PMC
February 2009

High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer.

Genome Biol 2007 ;8(10):R215

Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1186/gb-2007-8-10-r215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246289PMC
May 2008

High resolution melting for mutation scanning of TP53 exons 5-8.

BMC Cancer 2007 Aug 31;7:168. Epub 2007 Aug 31.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1186/1471-2407-7-168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025602PMC
August 2007

BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines.

Cancer Res 2007 Jul;67(14):6725-36

Cancer Genomics Program, Department of Oncology, University of Cambridge, Hutchison/Medical Research Council Research Center, Hills Road, Cambridge, United Kingdom.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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July 2007

A consensus prognostic gene expression classifier for ER positive breast cancer.

Genome Biol 2006 31;7(10):R101. Epub 2006 Oct 31.

Cancer Genomics Program, Department of Oncology, University of Cambridge, Hutchison/MRC Research Center, Hills Road, Cambridge CB2 2XZ, UK.

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http://link.springer.com/content/pdf/10.1186/gb-2006-7-10-r1
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http://genomebiology.com/2006/7/10/R101
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794561PMC
March 2007

Genomic analysis of the 8p11-12 amplicon in familial breast cancer.

Int J Cancer 2007 Feb;120(3):714-7

Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Center (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/ijc.22354DOI Listing
February 2007

MMASS: an optimized array-based method for assessing CpG island methylation.

Nucleic Acids Res 2006 13;34(20):e136. Epub 2006 Oct 13.

Department of Pathology, Division of Molecular Histopathology, Addenbrooke's Hospital Hills Road, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1093/nar/gkl551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635254PMC
December 2006

Metabolic consequences of p300 gene deletion in human colon cancer cells.

Cancer Res 2006 Aug;66(15):7606-14

Department of Biochemistry, Hutchison/Medical Research Council Research Centre, University of Cambridge, 80 Tennis Court Road, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2999DOI Listing
August 2006

Microarrays and breast cancer clinical studies: forgetting what we have not yet learnt.

Breast Cancer Res 2005 1;7(3):96-9. Epub 2005 Apr 1.

Cancer Genomics Programme, Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK.

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http://dx.doi.org/10.1186/bcr1017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143564PMC
January 2006

Molecular classification and molecular forecasting of breast cancer: ready for clinical application?

J Clin Oncol 2005 Oct 6;23(29):7350-60. Epub 2005 Sep 6.

Cancer Genomics Program, Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, United Kingdom CB22XZ.

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http://dx.doi.org/10.1200/JCO.2005.03.3845DOI Listing
October 2005

A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes.

Oncogene 2005 Aug;24(33):5235-45

Department of Oncology, Hutchison/MRC Research Centre, Cancer Genomics Program, University of Cambridge, Hills Road, Cambridge CB2 2XZ, UK.

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http://www.nature.com/articles/1208741
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August 2005

Sizing up miRNAs as cancer genes.

Nat Med 2005 Jul;11(7):712-4

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July 2005

Optimal amounts of fluorescent dye improve expression microarray results in tumor specimens.

Mol Biotechnol 2005 Jun;30(2):151-4

Cancer Genomics Program, Department of Oncology, University of Cambridge, Hutchison/MRC Research Center, Hills Road, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1385/MB:30:2:151DOI Listing
June 2005