Publications by authors named "James D Berry"

63Publications

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

N Engl J Med 2020 09;383(10):919-930

From the Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School (S.P., J.D.B., S.B., M.C., D.D., M.M., J.O., L.P., A.V.S., E.T., P.V., J. Walker, H.Y., R.E.T., M.E.C.), the Biostatistics Center, Massachusetts General Hospital, Harvard Medical School (E.A.M., J. Chan, D.S.), and Spaulding Rehabilitation Hospital, Harvard Medical School (S.P.), Boston, the University of Massachusetts Memorial Medical Center, Worcester (M.A.O.), and Amylyx Pharmaceuticals (J. Cohen, J. Klee, K.L., P.D.Y.) and Harvard University (W.G.), Cambridge - all in Massachusetts; Pentara, Millcreek, UT (S.H., S.P.D., N.E., K.H.); Swedish Neuroscience Institute, Seattle (M.A.E.); Hennepin Healthcare, Minneapolis (S.M.); the Department of Neurology, Oregon Health and Science University, Portland (C.K.); the Department of Neurology, Wake Forest School of Medicine, Winston-Salem, NC (J.B.C.); the Department of Neurology, Ohio State University College of Medicine, Columbus (A.Q.); the Department of Neurology, University of Florida College of Medicine, Gainesville (J. Wymer); the Department of Neurology, University of Michigan, Ann Arbor (S.A.G.); Texas Neurology, Dallas (D.H.); the Department of Neurology, Lewis Katz School of Medicine, Temple University (T.H.-P.), and the Department of Neurology, University of Pennsylvania Perelman School of Medicine (C.Q.) - both in Philadelphia; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Disease, University of Texas Health Science Center at San Antonio, San Antonio (C.E.J.); the Brain Science Institute and Department of Neurology, Johns Hopkins University, Baltimore (J.D.R.); the Department of Neurology, University of Kentucky College of Medicine, Lexington (E.J.K.); California Pacific Medical Center and Forbes Norris MDA-ALS Research and Treatment Center, San Francisco (J. Katz, L.J.); Barrow Neurological Institute, Phoenix, AZ (S.L., M.H., G.K., R.R., J.M.S.); the Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis (T.M.M.); the Department of Neurology, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, New York (S.N.S.); the Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (T.H.V.); the Departments of Neurology and Pathology, Emory University School of Medicine, Atlanta (C.N.F., J.D.G.); Ochsner Health System, New Orleans (K.M.J.); the Department of Neurology, University of Iowa Carver College of Medicine, Iowa City (A.S.); the Department of Neurology, University of California, Irvine, School of Medicine, Irvine (N.A.G.); Neurology Associates, Lincoln, NB (G.L.P.); independent consultant, Nobleboro, ME (P.L.A.); and Statistics Collaborative, Washington, DC (J. Wittes).

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http://dx.doi.org/10.1056/NEJMoa1916945DOI Listing
September 2020

Engaging ALS patients and caregivers (the ALS research ambassadors) to help design the REFINE-ALS biomarker study.

Amyotroph Lateral Scler Frontotemporal Degener 2020 Aug 24:1-4. Epub 2020 Aug 24.

Mitsubishi Tanabe Pharma America, Inc., Jersey City, NJ, USA.

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http://dx.doi.org/10.1080/21678421.2020.1804939DOI Listing
August 2020

Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS.

N Engl J Med 2020 07;383(2):151-158

From the Horae Gene Therapy Center, Department of Pediatrics, University of Massachusetts Medical School (UMMS) (C.M., G.G., M.B., T.R.F.), and the Department of Neurology, UMMS and UMass Memorial Medical Center (D.M.M.-Y., M.A.O., C.L.D., N.S.W., R.H.B.), Worcester, and the Healey Center for ALS, Department of Neurology (J.D.B., L.M.P., D.G., S.D.L., M.P.F., M.E.C.), and the C.S. Kubik Laboratory for Neuropathology (D.H.O., M.P.F.), Massachusetts General Hospital and Harvard Medical School, Boston.

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http://dx.doi.org/10.1056/NEJMoa2005056DOI Listing
July 2020

Optimizing telemedicine to facilitate amyotrophic lateral sclerosis clinical trials.

Muscle Nerve 2020 09 8;62(3):321-326. Epub 2020 Jun 8.

Department of Neurology, Penn State Health M.S. Hershey Medical Center, Hershey, Pennsylvania.

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http://dx.doi.org/10.1002/mus.26921DOI Listing
September 2020

Understanding the needs of people with ALS: a national survey of patients and caregivers.

Amyotroph Lateral Scler Frontotemporal Degener 2020 Aug 12;21(5-6):355-363. Epub 2020 May 12.

Healey Center for ALS, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1080/21678421.2020.1760889DOI Listing
August 2020

Lipocalin-2 is increased in amyotrophic lateral sclerosis.

Muscle Nerve 2020 08 29;62(2):272-283. Epub 2020 May 29.

Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/mus.26911DOI Listing
August 2020

Patient reported outcome measures (PROMs) in amyotrophic lateral sclerosis.

J Neurol 2020 Jun 3;267(6):1754-1759. Epub 2020 Mar 3.

Healey Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge St, Suite 600, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00415-020-09774-8DOI Listing
June 2020

Assessing Oromotor Capacity in ALS: The Effect of a Fixed-Target Task on Lip Biomechanics.

Front Neurol 2019 5;10:1288. Epub 2019 Dec 5.

Speech and Feeding Disorders Lab, MGH Institute of Health Professions, Boston, MA, United States.

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http://dx.doi.org/10.3389/fneur.2019.01288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906194PMC
December 2019

NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results.

Neurology 2019 12 18;93(24):e2294-e2305. Epub 2019 Nov 18.

From Massachusetts General Hospital Neurological Clinical Research Institute and Harvard Medical School (J.D.B., M.E.C., K.N.), Boston; Mayo Clinic (A.J.W., N.P.S.), Rochester, MN; University of Massachusetts (M.O., D.M.-Y., R.H.B.), Worcester; Brainstorm Cell Therapeutics (Y.S.L., N.A., H.K., R.A., Y.G.), Petach Tikva, Israel; and Tigermed USA (M.M.), Somerset, NJ.

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http://dx.doi.org/10.1212/WNL.0000000000008620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937497PMC
December 2019

Learning from history: Lord Brain and Hashimoto's encephalopathy.

Pract Neurol 2019 Aug 26;19(4):316-320. Epub 2019 Jun 26.

Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/practneurol-2018-002107DOI Listing
August 2019

Integration of a palliative care specialist in an amyotrophic lateral sclerosis clinic: Observations from one center.

Muscle Nerve 2019 08 20;60(2):137-140. Epub 2019 Jun 20.

Healey Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.26607DOI Listing
August 2019

Adjusted cost analysis of video televisits for the care of people with amyotrophic lateral sclerosis.

Muscle Nerve 2019 08 27;60(2):147-154. Epub 2019 Jun 27.

Harvard Medical School, Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, 165 Cambridge St, Suite 600, Boston, Massachusetts, 02114, USA.

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http://dx.doi.org/10.1002/mus.26606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772103PMC
August 2019

Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis.

Neurology 2019 04 29;92(18):e2089-e2100. Epub 2019 Mar 29.

From the Departments of Nutrition (K.B., Z.Z., É.J.O., D.D.W., A.A.) and Epidemiology (L.L., J.E.M., A.A.), Harvard T.H. Chan School of Public Health, Boston, MA; School of Public Health (É.J.O.), College of Medicine, University College Cork, Ireland; Department of Neurology (J.D.B., M.A.S.), Massachusetts General Hospital, Boston; Metabolomics Platform (C.B.C., A.D., S.J., K.A.P.), Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA; Department of Oncology (I.K.), Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI; Channing Division of Network Medicine (R.S.K., A.A.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Epidemiology Program (L.N.K., L.L.M.), University of Hawaii Cancer Center, Honolulu; Behavioral and Epidemiology Research Group (M.L.M.), American Cancer Society, Atlanta, GA; Department of Physical Medicine and Rehabilitation (S.P.), Spaulding Rehabilitation Hospital and Massachusetts General Hospital; Harvard Medical School (S.P., M.A.S.), Boston, MA; Family Medicine and Public Health (A.H.S.), School of Medicine, University of California San Diego; Epidemiology and Environmental Health, Public Health and Health Professions (J.W.-W.), University at Buffalo, NY; Behavioral and Epidemiology Research Group (Y.W.), American Cancer Society, Atlanta, GA; and Department of Medicine (J.E.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000007401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512888PMC
April 2019

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials.

Neurology 2019 04 8;92(14):e1610-e1623. Epub 2019 Mar 8.

From the Department of Neurology (L.H.v.d.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Neurology (E.S.), Mayo Clinic, Rochester, MN; Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City; Department of Medicine (E.A.M.), Massachusetts General Hospital, Biostatistics Center, Harvard Medical School, Boston; Department of Neurology (J.A., H.M.), Columbia University, Eleanor and Lou Gehrig ALS Center, New York, NY; Department of Neurology (R.H.B.), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (M.B.), University of Miami, FL; Neurological Clinical Research Institute (J.D.B.), Massachusetts General Hospital, Boston; Rita Levi Montalcini Department of Neuroscience (A.C.), University of Torino, Italy; Centre Constitutif SLA (P.C.), Université de Tours, France; Department of Neurology (A.G.), Clinical Research Unit, Montreal Neurological Institute, Neurosurgery, McGill University, Montreal, Canada; National Institute of Neurological Disorders and Stroke (A.K.G.), National Institutes of Health, Bethesda, MD; ALS Center (C.L.-H.), University of California San Francisco; Department of Neuroscience (C.J.M.), Sheffield Institute for Translational Neuroscience, University of Sheffield, UK; Department of Neurology (E.P.P.), Section of ALS & Related Disorders, Cleveland Clinic, OH; Department of Neurology (J.R.), The Center for Restorative Neurology, Loma Linda University School of Medicine, CA; Department of Neurology and Laboratory of Neuroscience (V.S.), Istituto Auxologico Italiano, IRCCS, Milan; Department of Pathophysiology and Transplantation (V.S.), "Dino Ferrari" Centre, Università degli Studi di Milano, Milan, Italy; Nuffield Department of Clinical Neurosciences (M.R.T.), University of Oxford, UK; Neuromuscular Diseases Unit/ALS Clinic (M.W.), Kantonsspital St. Gallen, Switzerland; Carolinas Neuromuscular/ALS-MDA Care Center (B.R.B.), Charlotte; Department of Neurology (B.R.B.), Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte; Forbes Norris ALS Treatment and Research Center (R.G.M.), California Pacific Medical Center San Francisco; and Department of Neurosciences (R.G.M.), Stanford University, CA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000007242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448453PMC
April 2019

Heterogeneity, urgency, generalizability, and enrollment: The HUGE balance in ALS trials.

Neurology 2019 Jan 9. Epub 2019 Jan 9.

From the Department of Neurology (C.K.), Oregon Health & Science University, Portland; and Department of Neurology (J.D.B.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000006837DOI Listing
January 2019

Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis.

Neurology 2019 04 14;92(18):e2081-e2088. Epub 2018 Nov 14.

From the Departments of Nutrition (K.B., É.J.O., Z.Z., A.A.) and Epidemiology (J.E.M., A.A.), Harvard T.H. Chan School of Public Health, Boston, MA; School of Public Health (É.J.O.), College of Medicine, University College Cork, Ireland; Department of Neurology (J.D.B., M.A.S.), Massachusetts General Hospital (S.P.), Boston; Metabolomics Platform (C.B.C., S.J.), Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge; Department of Oncology (I.K.), Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI; Epidemiology Program (L.N.K., L.L.M.), University of Hawaii Cancer Center, Honolulu; Epidemiology Research Program (M.L.M.), American Cancer Society, Atlanta, GA; Department of Physical Medicine and Rehabilitation (S.P.), Spaulding Rehabilitation Hospital, Charlestown; Harvard Medical School (S.P., M.A.S.), Boston, MA; Department of Epidemiology (E.O.T.), Graduate School of Public Health, University of Pittsburgh, PA; Department of Epidemiology (R.B.W.), College of Public Health, University of Iowa, Iowa City; and Department of Medicine (J.E.M.) and Channing Division of Network Medicine (A.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000006669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512885PMC
April 2019

Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study.

Neurol Neuroimmunol Neuroinflamm 2018 Jul 18;5(4):e465. Epub 2018 May 18.

Houston Methodist Neurological Institute (J.R.T., D.R.B., W.Z., M.P., E.P.S., S.H.A.), Houston Methodist Hospital Research Institute, Stanley H. Appel Department of Neurology, Houston, TX; and Neurological Clinical Research Institute (J.D.B., M.E.C.), Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1212/NXI.0000000000000465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961523PMC
July 2018

Improved stratification of ALS clinical trials using predicted survival.

Ann Clin Transl Neurol 2018 Apr 9;5(4):474-485. Epub 2018 Mar 9.

Voyager Therapeutics, Inc. Cambridge Massachusetts.

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http://dx.doi.org/10.1002/acn3.550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899911PMC
April 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis.

Muscle Nerve 2018 Aug 25;58(2):261-269. Epub 2018 Mar 25.

Department of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.26106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103911PMC
August 2018

Experience with telemedicine in a multi-disciplinary ALS clinic.

Amyotroph Lateral Scler Frontotemporal Degener 2018 02 18;19(1-2):143-148. Epub 2017 Dec 18.

a Harvard Medical School , Spaulding Rehabilitation Hospital , Charlestown , MA , USA.

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http://dx.doi.org/10.1080/21678421.2017.1392577DOI Listing
February 2018

Developing multidisciplinary clinics for neuromuscular care and research.

Muscle Nerve 2017 Nov 29;56(5):848-858. Epub 2017 Aug 29.

Harvard Medical School, Department of Neurology, Massachusetts General Hospital (MGH), Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.25725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656914PMC
November 2017

Poly(GP) proteins are a useful pharmacodynamic marker for -associated amyotrophic lateral sclerosis.

Sci Transl Med 2017 03;9(383)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1126/scitranslmed.aai7866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576451PMC
March 2017

The diagnostic utility of patient-report and speech-language pathologists' ratings for detecting the early onset of bulbar symptoms due to ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2017 08 29;18(5-6):358-366. Epub 2017 Mar 29.

a Department of Communication Sciences and Disorders , MGH Institute of Health Professions , Boston , MA , USA.

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http://dx.doi.org/10.1080/21678421.2017.1303515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530595PMC
August 2017

Predicting Speech Intelligibility Decline in Amyotrophic Lateral Sclerosis Based on the Deterioration of Individual Speech Subsystems.

PLoS One 2016 5;11(5):e0154971. Epub 2016 May 5.

Department of Communication Sciences and Disorders, MGH Institute of Health Professions, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858181PMC
July 2017

Preclinical Rodent Toxicity Studies for Long Term Use of Ceftriaxone.

Toxicol Rep 2015;2:1396-1403

Neurological Clinical Research Institute (NCRI), Massachusetts General Hospital, Boston, MA, Massachusetts General Hospital, 165 Cambridge Street, Suite 600, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.toxrep.2015.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685718PMC
January 2015

Amyotrophic Lateral Sclerosis: Review.

Semin Neurol 2015 Aug 6;35(4):469-76. Epub 2015 Oct 6.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1055/s-0035-1558984DOI Listing
August 2015

Clinical Trial Designs in Amyotrophic Lateral Sclerosis: Does One Design Fit All?

Neurotherapeutics 2015 Apr;12(2):376-83

Massachusetts General Hospital, Department of Neurology, Neurological Clinical Research Institute, 165 Cambridge Street, Suite 600, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s13311-015-0341-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404442PMC
April 2015

Electrical impedance myography in the evaluation of the tongue musculature in amyotrophic lateral sclerosis.

Muscle Nerve 2015 Oct 3;52(4):584-91. Epub 2015 Jun 3.

ALS/MND Clinic, Sunnybrook Health Sciences Centre, Department of Neurology, University of Toronto, Toronto, Canada.

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http://doi.wiley.com/10.1002/mus.24565
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http://dx.doi.org/10.1002/mus.24565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499330PMC
October 2015

Neuroprotective agents target molecular mechanisms of disease in ALS.

Drug Discov Today 2015 Jan 6;20(1):65-75. Epub 2014 Sep 6.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.08.016DOI Listing
January 2015

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.

Mol Biol Cell 2014 Sep 9;25(17):2571-8. Epub 2014 Jul 9.

Howard Hughes Medical Institute, Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO 80309

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http://www.molbiolcell.org/doi/10.1091/mbc.e14-05-1007
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http://dx.doi.org/10.1091/mbc.E14-05-1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148247PMC
September 2014

Reevaluating the risk of DVT in people with ALS: weak in the knees and DVTs.

Neurology 2014 May 11;82(19):1668-9. Epub 2014 Apr 11.

From the Neurological Clinical Research Institute (J.D.B.), Massachusetts General Hospital, Boston; and the Hotchkiss Brain Institute (L.K.), University of Calgary, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000000420DOI Listing
May 2014

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.

Cell Rep 2014 Apr 3;7(1):1-11. Epub 2014 Apr 3.

FM Kirby Neurobiology Center, Boston Children's Hospital and Harvard Stem Cell Institute, Boston, MA 02115, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023477PMC
April 2014

Predicting success: optimizing phase II ALS trials for the transition to phase III.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Mar;15(1-2):1-8

Massachusetts General Hospital, Neurological Clinical Research Center , Boston, Massachusetts.

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http://dx.doi.org/10.3109/21678421.2013.838969DOI Listing
March 2014

Outcome measures in amyotrophic lateral sclerosis clinical trials.

Clin Investig (Lond) 2014 ;4(7):605-618

Harvard Medical School, Department of Neurology, Neurological Clinical Research Institute (NCRI), Massachusetts Genera Hospital, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305182PMC
http://dx.doi.org/10.4155/cli.14.52DOI Listing
January 2014

Feedback interaction of research, advocacy, and clinical care applied to ALS research in South America.

Neurology 2013 Nov;81(22):1959-61

From the University of Massachusetts Medical School (M.E.B., J.S.), Worcester; San Francisco University of Quito (A.C., D.C., C.F., R.L.), Ecuador; Wellesley College (E.D.), MA; and Massachusetts General Hospital (N.A., J.D.B.), Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/01.wnl.0000436610.28210.a5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843379PMC
November 2013

Bulbar and speech motor assessment in ALS: challenges and future directions.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 30;14(7-8):494-500. Epub 2013 Jul 30.

The Department of Communication Sciences and Disorders, MGH Institute of Health Professions , Massachusetts , USA.

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http://dx.doi.org/10.3109/21678421.2013.817585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833808PMC
December 2013

The Combined Assessment of Function and Survival (CAFS): a new endpoint for ALS clinical trials.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Apr 17;14(3):162-8. Epub 2013 Jan 17.

Massachusetts General Hospital, Neurological Clinical Research Institute, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.3109/21678421.2012.762930DOI Listing
April 2013

Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study: subgroup analysis of demographic and clinical characteristics.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Jan 17;14(1):44-51. Epub 2012 Sep 17.

Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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http://dx.doi.org/10.3109/17482968.2012.723723DOI Listing
January 2013

New considerations in the design of clinical trials for amyotrophic lateral sclerosis.

Clin Investig (Lond) 2011 Oct;1(10):1375-1389

Massachusetts General Hospital, Department of Neurology, Neurology Clinical Trials Unit, 149 Thirteenth Street, Suite 2274, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.4155/cli.11.127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335743PMC
October 2011

Biochemical alterations associated with ALS.

Amyotroph Lateral Scler 2012 Jan 25;13(1):110-8. Epub 2011 Nov 25.

Metabolon Inc., North Carolina, USA.

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http://dx.doi.org/10.3109/17482968.2011.619197DOI Listing
January 2012

A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster.

Neurology 2005 Aug;65(3):444-7

UCSF Pain Clinical Research Center, Department of Neurology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1212/01.wnl.0000168259.94991.8aDOI Listing
August 2005

Complex regional pain syndrome-like symptoms during herpes zoster.

Pain 2004 Jul;110(1-2):e1-12

UCSF Pain Clinical Research Center, University of California, San Francisco 94115, USA.

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http://dx.doi.org/10.1016/j.pain.2003.12.038DOI Listing
July 2004