James D Baleja

James D Baleja

UNVERIFIED PROFILE

Are you James D Baleja?   Register this Author

Register author
James D Baleja

James D Baleja

Publications by authors named "James D Baleja"

Are you James D Baleja?   Register this Author

35Publications

391Reads

38Profile Views

Amino Acid Biosynthetic Pathways Are Required for Growth in Immunocompromised Lungs and Are Druggable Targets during Infection.

Antimicrob Agents Chemother 2019 Aug 25;63(8). Epub 2019 Jul 25.

Graduate Program in Immunology, MERGE-ID Track, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02674-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658747PMC
August 2019

A unique model for SDH-deficient GIST: an endocrine-related cancer.

Endocr Relat Cancer 2018 11 2;25(11):943-954. Epub 2018 Jul 2.

Department of Pathology and Laboratory Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/ERC-18-0115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097913PMC
November 2018

Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG.

Int J Pharm 2017 Oct 24;532(1):149-156. Epub 2017 Aug 24.

Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03785173173081
Publisher Site
http://dx.doi.org/10.1016/j.ijpharm.2017.08.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628159PMC
October 2017

Quorum Sensing Coordinates Cooperative Expression of Pyruvate Metabolism Genes To Maintain a Sustainable Environment for Population Stability.

MBio 2016 12 6;7(6). Epub 2016 Dec 6.

Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mBio.01863-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142617PMC
December 2016

Targeting Liver Fibrosis with a Cell-penetrating Protease-activated Receptor-2 (PAR2) Pepducin.

J Biol Chem 2016 10 9;291(44):23188-23198. Epub 2016 Sep 9.

From the Center for Hemostasis and Thrombosis Research, Molecular Oncology Research Institute, Tufts Medical Center and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M116.732743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087736PMC
October 2016

Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics.

J Biol Chem 2015 Jun 1;290(25):15785-98. Epub 2015 May 1.

From the Center of Hemostasis and Thrombosis Research, Molecular Oncology Research Institute, Tufts Medical Center, and Departments of Biochemistry and Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.636316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505487PMC
June 2015

A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake.

Bioorg Med Chem 2014 Nov 2;22(22):6387-91. Epub 2014 Oct 2.

Department of Chemistry, Tufts University, 62 Talbot Ave., Medford, MA 02155, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2014.09.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254597PMC
November 2014

Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function.

PLoS One 2013 23;8(12):e84506. Epub 2013 Dec 23.

Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America ; Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084506PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871595PMC
October 2014

Structured cyclic peptides that bind the EH domain of EHD1.

Biochemistry 2014 Jul 17;53(29):4758-60. Epub 2014 Jul 17.

Department of Chemistry, Tufts University , 62 Talbot Avenue, Medford, Massachusetts 02155, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi500744qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116148PMC
July 2014

Structural analysis of the N-terminal domain of subunit a of the yeast vacuolar ATPase (V-ATPase) using accessibility of single cysteine substitutions to chemical modification.

J Biol Chem 2013 Aug 5;288(31):22798-808. Epub 2013 Jun 5.

Department of Molecular Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.460295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829364PMC
August 2013

Backbone resonance assignments of the C2 domain of coagulation factor VIII.

Biomol NMR Assign 2013 Apr 6;7(1):31-4. Epub 2012 Mar 6.

Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12104-012-9370-5DOI Listing
April 2013

Molecular remodeling mechanisms of the neural somatodendritic compartment.

Biochim Biophys Acta 2012 Oct 15;1823(10):1720-30. Epub 2012 Jun 15.

Department of Biochemistry, Tufts University School of Medicine, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2012.06.006DOI Listing
October 2012

Cross-strand interactions of fluorinated amino acids in β-hairpin constructs.

J Am Chem Soc 2012 Oct 18;134(43):17912-21. Epub 2012 Oct 18.

Department of Chemistry, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja212080fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574618PMC
October 2012

Reps2: a cellular signaling and molecular trafficking nexus.

Int J Biochem Cell Biol 2011 Dec 3;43(12):1660-3. Epub 2011 Sep 3.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, United States.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13572725110023
Publisher Site
http://dx.doi.org/10.1016/j.biocel.2011.08.014DOI Listing
December 2011

Design and characterization of an enhanced repressor of human papillomavirus E2 protein.

FASEB J 2011 Jul 11;25(7):2354-61. Epub 2011 Apr 11.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.10-176461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114532PMC
July 2011

Membrane-binding properties of the Factor VIII C2 domain.

Biochem J 2011 Apr;435(1):187-96

Department of Medicine, Veterans Affairs Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02132, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20101797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670696PMC
April 2011

Charge effects in the selection of NPF motifs by the EH domain of EHD1.

Biochemistry 2010 Apr;49(16):3381-92

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi100065rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857698PMC
April 2010

Determinants of stability for the E6 protein of papillomavirus type 16.

J Mol Biol 2009 Mar;386(4):1123-37

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768073PMC
http://dx.doi.org/10.1016/j.jmb.2009.01.018DOI Listing
March 2009

Disorder and structure in the Rab11 binding domain of Rab11 family interacting protein 2.

Biochemistry 2009 Jan;48(3):549-57

Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi8020197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640498PMC
January 2009

Engineering and characterization of a single chain surrogate light chain variable domain.

Protein Sci 2008 Mar;17(3):458-65

Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1110/ps.073269808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248314PMC
March 2008

Structure and function of the papillomavirus E6 protein and its interacting proteins.

Front Biosci 2008 Jan 1;13:121-34. Epub 2008 Jan 1.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2741/2664DOI Listing
January 2008

Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.

Biochemistry 2007 Sep 22;46(38):10864-74. Epub 2007 Aug 22.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi700879kDOI Listing
September 2007

The role of conserved histidines in the structure and stability of human papillomavirus type 16 E2 DNA-binding domain.

Biochemistry 2007 Feb;46(5):1402-11

Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/bi0611255
Publisher Site
http://dx.doi.org/10.1021/bi0611255DOI Listing
February 2007

Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins.

Antiviral Res 2006 Oct 21;72(1):49-59. Epub 2006 Apr 21.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.antiviral.2006.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776632PMC
October 2006

Molecular dissection of Rab11 binding from coiled-coil formation in the Rab11-FIP2 C-terminal domain.

Biochemistry 2006 Jun;45(22):6826-34

Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi052655oDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518868PMC
June 2006

Identification of a region of fast skeletal troponin T required for stabilization of the coiled-coil formation with troponin I.

J Biol Chem 2005 Jan 26;280(1):538-47. Epub 2004 Oct 26.

Program in Cell, Molecular and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M409537200DOI Listing
January 2005

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus.

Biochemistry 2004 Jun;43(23):7421-31

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi049552aDOI Listing
June 2004

Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding.

Chem Biol 2003 Nov;10(11):1033-41

Division of Hematology/Oncology and Department of Medicine, New England Medical Center, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
November 2003

Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors.

J Biol Chem 2002 Dec 2;277(51):49158-66. Epub 2002 Oct 2.

Department of Biochemistry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M206316200DOI Listing
December 2002

Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer.

J Biol Chem 2002 Sep 16;277(39):36465-70. Epub 2002 Jul 16.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M206018200DOI Listing
September 2002

Localization of subunits D, E, and G in the yeast V-ATPase complex using cysteine-mediated cross-linking to subunit B.

Biochemistry 2002 Sep;41(37):11301-7

Department of Physiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0262449DOI Listing
September 2002

Cysteine-directed cross-linking to subunit B suggests that subunit E forms part of the peripheral stalk of the vacuolar H+-ATPase.

J Biol Chem 2002 Feb 27;277(5):3357-63. Epub 2001 Nov 27.

Departments of Physiology and Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M109967200
Publisher Site
http://dx.doi.org/10.1074/jbc.M109967200DOI Listing
February 2002