james cook

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Comparison of real-time PCR vs PCR with fragment length analysis for the detection of CALR mutations in suspected myeloproliferative neoplasms.

Authors:
Laura J Doyle Bryan L Betz Helmut C Weigelin Gary W Procop James R Cook

Int J Lab Hematol 2019 12 3;41(6):e139-e141. Epub 2019 May 3.

Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1111/ijlh.13040DOI Listing
December 2019

Three-dimensional Printing Technology in Orthopaedics.

Authors:
Nathan Wm Skelley Matthew J Smith Richard Ma James L Cook

J Am Acad Orthop Surg 2019 Dec;27(24):918-925

From the The Missouri Orthopaedic Institute-The University of Missouri, Department of Orthopaedic Surgery & Thompson Laboratory for Regenerative Orthopaedics, Columbia, MO.

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http://dx.doi.org/10.5435/JAAOS-D-18-00746DOI Listing
December 2019

An Ecological Loop: Host Microbiomes across Multitrophic Interactions.

Authors:
Hongwei Liu Catriona A Macdonald James Cook Ian C Anderson Brajesh K Singh

Trends Ecol Evol 2019 Dec 15;34(12):1118-1130. Epub 2019 Aug 15.

Hawkesbury Institute for the Environment, Western Sydney University, Penrith, NSW 2753, Australia; Global Centre for Land-Based Innovation, Western Sydney University, Penrith, NSW 2753, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.tree.2019.07.011DOI Listing
December 2019

Neuronal ceroid lipofuscinosis in a German Shorthaired Pointer associated with a previously reported nonsense variant.

Authors:
Juyuan Guo Gary S Johnson James Cook Olivia K Harris Tendai Mhlanga-Mutangadura Robert D Schnabel Cheryl A Jensen Martin L Katz

Mol Genet Metab Rep 2019 Dec 21;21:100521. Epub 2019 Oct 21.

Neurodegenerative Diseases Research Laboratory, Department of Ophthalmology, University of Missouri, Columbia, MO, USA.

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http://dx.doi.org/10.1016/j.ymgmr.2019.100521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819867PMC
December 2019

Sustained Low-dose Dexamethasone Delivery Via a PLGA Microsphere-embedded Agarose Implant for Enhanced Osteochondral Repair.

Authors:
Robert M Stefani Andy J Lee Andrea R Tan Saiti S Halder Yizhong Hu X Edward Guo Aaron M Stoker Gerard A Ateshian Kacey G Marra James L Cook Clark T Hung

Acta Biomater 2019 Dec 2. Epub 2019 Dec 2.

Columbia University, Department of Biomedical Engineering, 351 Engineering Terrace, 1210 Amsterdam Avenue, New York, NY 10027. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.11.052DOI Listing
December 2019

The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81.

Authors:
Jeffrey M Witkin Xingjie Ping Rok Cerne Claire Mouser Xiaoming Jin Jon Hobbs Veera Venkata Naga Phani Babu Tiruveedhula Guanguan Li Rajwana Jahan Farjana Rashid Lalit Kumar Golani James M Cook Jodi L Smith

Brain Res 2019 Nov 29;1722:146356. Epub 2019 Jul 29.

Laboratory of Antiepileptic Drug Discovery, St. Vincent's Hospital, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2019.146356DOI Listing
November 2019

Correction to "A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABA Receptors in the Lung".

Authors:
Gloria S Forkuo Amanda N Nieman Revathi Kodali Nicolas M Zahn Guanguan Li M S Rashid Roni Michael Rajesh Stephen Ted W Harris Rajwana Jahan Margaret L Guthrie Olivia B Yu Janet L Fisher Gene T Yocum Charles W Emala Douglas A Steeber Douglas C Stafford James M Cook Leggy A Arnold

Mol Pharm 2019 Nov 21;16(11):4756. Epub 2019 Oct 21.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b01053DOI Listing
November 2019

Enhanced Subchondroplasty Treatment for Post-Traumatic Cartilage and Subchondral Bone Marrow Lesions in a Canine Model.

Authors:
Harvey A Oliver Chantelle C Bozynski Cristi R Cook Keiichi Kuroki Seth L Sherman Aaron M Stoker James L Cook

J Orthop Res 2019 Nov 6. Epub 2019 Nov 6.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1002/jor.24508DOI Listing
November 2019

The positive allosteric modulator of α2/3-containing GABAA receptors, KRM-II-81, is active in pharmaco-resistant models of epilepsy and reduces hyperexcitability after traumatic brain injury.

Authors:
Jeffrey M Witkin Guanguan Li Lalit K Golani Wenhui Xiong Jodi L Smith Xingjie Ping Farjana Rashid Rajwana Jahan Rok Cerne James M Cook Xiaoming Jin

J Pharmacol Exp Ther 2019 Nov 6. Epub 2019 Nov 6.

Indiana University.

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http://dx.doi.org/10.1124/jpet.119.260968DOI Listing
November 2019

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

Authors:
Paul McCusker Md Yeunus Mian Guanguan Li Michael D Olp V V N Phani Babu Tiruveedhula Farjana Rashid Lalit Kumar Golani Ranjit S Verma Brian C Smith James M Cook John D Chan

PLoS Negl Trop Dis 2019 Nov 15;13(11):e0007826. Epub 2019 Nov 15.

Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, WI, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881066PMC
November 2019

Effects of Compliance With Procedure-Specific Postoperative Rehabilitation Protocols on Initial Outcomes After Osteochondral and Meniscal Allograft Transplantation in the Knee.

Authors:
Kylee Rucinski James L Cook Cory R Crecelius Renée Stucky James P Stannard

Orthop J Sports Med 2019 Nov 22;7(11):2325967119884291. Epub 2019 Nov 22.

Department of Orthopaedic Surgery, Thompson Laboratory for Regenerative Orthopaedics, Mizzou BioJoint Center, Missouri Orthopaedic Institute, University of Missouri, Columbia, Missouri, USA.

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http://dx.doi.org/10.1177/2325967119884291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876180PMC
November 2019

Onlay Reconstruction of the Posterior Cruciate Ligament: Biomechanical Comparison of Unicortical and Bicortical Tibial Fixation.

Authors:
João Bourbon de Albuquerque Ii Ferris Pfeiffer James P Stannard James L Cook Mauricio Kfuri

J Knee Surg 2019 Oct 3;32(10):972-978. Epub 2018 Oct 3.

Departamento de Biomecanica, Medicina e Reabilitacao do Aparelho Locomotor, Universidade de Sao Paulo Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, Brazil.

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http://dx.doi.org/10.1055/s-0038-1672205DOI Listing
October 2019

Clinical outcomes after common calcanean tendon rupture repair in dogs with a loop-suture tenorrhaphy technique and autogenous leukoreduced platelet-rich plasma.

Authors:
Kurt S Schulz Krisitan J Ash James L Cook

Vet Surg 2019 Oct 4;48(7):1262-1270. Epub 2019 Apr 4.

Thompson Laboratory for Regenerative Orthopaedics & Mizzou BioJoint® Center, Missouri Orthopedic Institute, Columbia, Missouri.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/vsu.13208
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http://dx.doi.org/10.1111/vsu.13208DOI Listing
October 2019

Class-switched Primary Cutaneous Marginal Zone Lymphomas Are Frequently IgG4-positive and Have Features Distinct From IgM-positive Cases.

Authors:
Eric D Carlsen Steven H Swerdlow James R Cook Sarah E Gibson

Am J Surg Pathol 2019 Oct;43(10):1403-1412

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PAS.0000000000001363DOI Listing
October 2019

Evaluation of the anti-conflict, reinforcing, and sedative effects of YT-III-31, a ligand functionally selective for α3 subunit-containing GABA receptors.

Authors:
Zhiqiang Meng Lais F Berro Eileen K Sawyer Daniela Rüedi-Bettschen Jemma E Cook Guanguan Li Donna M Platt James M Cook James K Rowlett

J Psychopharmacol 2019 Oct 31:269881119882803. Epub 2019 Oct 31.

Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA.

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http://dx.doi.org/10.1177/0269881119882803DOI Listing
October 2019

Molecular and Cytogenetic Education in Hematopathology Fellowship.

Authors:
Lorinda A Soma Alexandra E Kovach Alexa J Siddon Rose Beck Sarah E Gibson Steven H Swerdlow Annette S Kim David Wu Dan Jones James R Cook Sonam Prakash Flavia Rosado Genevieve Crane Kyle Bradley Olga K Weinberg Rachel L Sargent

Am J Clin Pathol 2019 Sep;152(4):438-445

Oncology Diagnostics, Janssen Research and Development, Spring House, PA.

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http://dx.doi.org/10.1093/ajcp/aqz048DOI Listing
September 2019

Do neoprene sleeves and prophylactic knee braces affect neuromuscular control and cutting agility?

Authors:
Blake M Bodendorfer Nicholas R Arnold Henry T Shu Emily V Leary James L Cook Aaron D Gray Trent M Guess Seth L Sherman

Phys Ther Sport 2019 Sep 24;39:23-31. Epub 2019 May 24.

University of Missouri Health Care, Columbia, MO, USA.

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http://dx.doi.org/10.1016/j.ptsp.2019.05.007DOI Listing
September 2019

Myeloid neoplasm with eosinophilia and fusion.

Authors:
James R Cook Heesun J Rogers Pranil K Chandra James L Prescott Sudipto Mukherjee

Leuk Lymphoma 2019 Sep 4:1-4. Epub 2019 Sep 4.

Taussig Cancer Institute, Cleveland Clinic , Cleveland , OH , USA.

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http://dx.doi.org/10.1080/10428194.2019.1658105DOI Listing
September 2019

As the world turns, evolving lymphoma classifications - past, present and future.

Authors:
Steven H Swerdlow James R Cook

Hum Pathol 2019 Sep 4. Epub 2019 Sep 4.

Department of Laboratory Medicine, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2019.08.019DOI Listing
September 2019

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Authors:
Alexander Teumer Yong Li Sahar Ghasemi Bram P Prins Matthias Wuttke Tobias Hermle Ayush Giri Karsten B Sieber Chengxiang Qiu Holger Kirsten Adrienne Tin Audrey Y Chu Nisha Bansal Mary F Feitosa Lihua Wang Jin-Fang Chai Massimiliano Cocca Christian Fuchsberger Mathias Gorski Anselm Hoppmann Katrin Horn Man Li Jonathan Marten Damia Noce Teresa Nutile Sanaz Sedaghat Gardar Sveinbjornsson Bamidele O Tayo Peter J van der Most Yizhe Xu Zhi Yu Lea Gerstner Johan Ärnlöv Stephan J L Bakker Daniela Baptista Mary L Biggs Eric Boerwinkle Hermann Brenner Ralph Burkhardt Robert J Carroll Miao-Li Chee Miao-Ling Chee Mengmeng Chen Ching-Yu Cheng James P Cook Josef Coresh Tanguy Corre John Danesh Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Katalin Dittrich Jasmin Divers Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Janine F Felix Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Ron T Gansevoort Vilmantas Giedraitis Martin Gögele Franziska Grundner-Culemann Daniel F Gudbjartsson Vilmundur Gudnason Pavel Hamet Tamara B Harris Andrew A Hicks Hilma Holm Valencia Hui Xian Foo Shih-Jen Hwang M Arfan Ikram Erik Ingelsson Vincent W V Jaddoe Johanna Jakobsdottir Navya Shilpa Josyula Bettina Jung Mika Kähönen Chiea-Chuen Khor Wieland Kiess Wolfgang Koenig Antje Körner Peter Kovacs Holly Kramer Bernhard K Krämer Florian Kronenberg Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jianjun Liu Markus Loeffler Leo-Pekka Lyytikäinen Anubha Mahajan Joseph C Maranville Deborah Mascalzoni Barbara McMullen Christa Meisinger Thomas Meitinger Kozeta Miliku Dennis O Mook-Kanamori Martina Müller-Nurasyid Josyf C Mychaleckyj Matthias Nauck Kjell Nikus Boting Ning Raymond Noordam Jeffrey O' Connell Isleifur Olafsson Nicholette D Palmer Annette Peters Anna I Podgornaia Belen Ponte Tanja Poulain Peter P Pramstaller Ton J Rabelink Laura M Raffield Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Fernando Rivadeneira Heiko Runz Kathleen A Ryan Charumathi Sabanayagam Kai-Uwe Saum Ben Schöttker Christian M Shaffer Yuan Shi Albert V Smith Konstantin Strauch Michael Stumvoll Benjamin B Sun Silke Szymczak E-Shyong Tai Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Unnur Thorsteinsdottir Anke Tönjes Johanne Tremblay André G Uitterlinden Pim van der Harst Niek Verweij Suzanne Vogelezang Uwe Völker Melanie Waldenberger Chaolong Wang Otis D Wilson Charlene Wong Tien-Yin Wong Qiong Yang Masayuki Yasuda Shreeram Akilesh Murielle Bochud Carsten A Böger Olivier Devuyst Todd L Edwards Kevin Ho Andrew P Morris Afshin Parsa Sarah A Pendergrass Bruce M Psaty Jerome I Rotter Kari Stefansson James G Wilson Katalin Susztak Harold Snieder Iris M Heid Markus Scholz Adam S Butterworth Adriana M Hung Cristian Pattaro Anna Köttgen

Nat Commun 2019 Sep 11;10(1):4130. Epub 2019 Sep 11.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41467-019-11576-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739370PMC
September 2019

Metabolic responses of meniscal tissue to focal collagenase degeneration.

Authors:
Kamryn S Chastain Aaron M Stoker Chantelle C Bozynski Emily V Leary James L Cook

Connect Tissue Res 2019 Sep 23:1-11. Epub 2019 Sep 23.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri , Columbia , MO , USA.

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http://dx.doi.org/10.1080/03008207.2019.1666112DOI Listing
September 2019

Autologous transplantation as consolidation for high risk aggressive T-cell non-Hodgkin lymphoma: a SWOG 9704 intergroup trial subgroup analysis.

Authors:
Zeina Al-Mansour Hongli Li James R Cook Louis S Constine Stephen Couban Douglas A Stewart Thomas C Shea Pierluigi Porcu Jane N Winter Brad S Kahl Sonali M Smith Deborah C Marcellus Kevin P Barton Glenn M Mills Michael LeBlanc Lisa M Rimsza Stephen J Forman John P Leonard Richard I Fisher Jonathan W Friedberg Patrick J Stiff

Leuk Lymphoma 2019 Aug 10;60(8):1934-1941. Epub 2019 Jan 10.

a Cardinal Bernardin Cancer Center, Loyola University Medical Center , Maywood , IL , USA.

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https://www.tandfonline.com/doi/full/10.1080/10428194.2018.1
Publisher Site
http://dx.doi.org/10.1080/10428194.2018.1563691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620162PMC
August 2019

Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam.

Authors:
Megan J Moerke Guanguan Li Lalit K Golani James Cook S Stevens Negus

Behav Pharmacol 2019 08;30(5):452-461

Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1097/FBP.0000000000000464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610697PMC
August 2019

Very rare lineage switch from acute myeloid leukemia to mixed phenotype acute leukemia, B/Myeloid, during chemotherapy with no clonal evolution.

Authors:
Laila Nomani James R Cook Heesun J Rogers

Int J Lab Hematol 2019 08 1;41(4):e86-e88. Epub 2019 Feb 1.

Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1111/ijlh.12977DOI Listing
August 2019

Editorial Commentary: Bone Marrow Aspirate Biologics for Osteochondral Allografts-Because We Can or Because We Should?

Authors:
James L Cook

Arthroscopy 2019 Aug;35(8):2445-2447

University of Missouri.

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http://dx.doi.org/10.1016/j.arthro.2019.04.018DOI Listing
August 2019

T1ρ, T2 mapping, and EPIC-µCT Imaging in a Canine Model of Knee Osteochondral Injury.

Authors:
Samuel P Franklin Aaron M Stoker Angela S P Lin Sarah L Pownder Emily E Burke Chantelle C Bozynski Kei Kuroki Robert E Guldberg James L Cook Shannon P Holmes

J Orthop Res 2019 Aug 20. Epub 2019 Aug 20.

Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, Georgia.

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http://dx.doi.org/10.1002/jor.24450DOI Listing
August 2019

Patellar Bone-Tendon-Bone Autografts versus Quadriceps Tendon Allograft with Synthetic Augmentation in a Canine Model.

Authors:
Patrick A Smith James P Stannard Chantelle C Bozynski Keiichi Kuroki Cristi R Cook James L Cook

J Knee Surg 2019 Aug 28. Epub 2019 Aug 28.

Department of Orthopedic Surgery, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0039-1695040DOI Listing
August 2019

Identification of "Double Hit" Lymphomas Using Updated WHO Criteria: Insights From Routine MYC Immunohistochemistry in 272 Consecutive Cases of Aggressive B-Cell Lymphomas.

Authors:
Hany Sakr James R Cook

Appl Immunohistochem Mol Morphol 2019 Jul;27(6):410-415

Department of Laboratory Medicine, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1097/PAI.0000000000000657DOI Listing
July 2019

Small Animal Multivariate Brain Analysis (SAMBA) - a High Throughput Pipeline with a Validation Framework.

Authors:
Robert J Anderson James J Cook Natalie Delpratt John C Nouls Bin Gu James O McNamara Brian B Avants G Allan Johnson Alexandra Badea

Neuroinformatics 2019 Jul;17(3):451-472

Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s12021-018-9410-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584586PMC
July 2019

MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABA receptors without causing systemic immune suppression.

Authors:
Nicolas M Zahn Alec T Huber Brandon N Mikulsky Mae E Stepanski Alexander S Kehoe Guanguan Li Melissa Schussman Mohammed S Rashid Roni Revathi Kodali James M Cook Douglas C Stafford Douglas A Steeber Leggy A Arnold

Basic Clin Pharmacol Toxicol 2019 Jul 21;125(1):75-84. Epub 2019 Feb 21.

Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1111/bcpt.13206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565495PMC
July 2019

Effect of dose and release rate of CTGF and TGFβ3 on avascular meniscus healing.

Authors:
Solaiman Tarafder Joseph Gulko Daniel Kim Kun Hee Sim Shawn Gutman Jian Yang James L Cook Chang H Lee

J Orthop Res 2019 07 28;37(7):1555-1562. Epub 2019 Mar 28.

Regenerative Engineering Laboratory, Columbia University Irving Medical Center, 630 W. 168 St. - VC12-230, New York 10032, New York.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.24287
Publisher Site
http://dx.doi.org/10.1002/jor.24287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601329PMC
July 2019

Metabolic responses of osteochondral allografts to re-warming.

Authors:
Aaron M Stoker Katherine M Caldwell James P Stannard James L Cook

J Orthop Res 2019 07 28;37(7):1530-1536. Epub 2019 Mar 28.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1002/jor.24290DOI Listing
July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2019 Jul;51(7):1191-1192

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-019-0447-2DOI Listing
July 2019

E1A oncogene induced sensitization to NK cell induced apoptosis requires PIDD and Caspase-2.

Authors:
Jay R Radke John M Routes James L Cook

Cell Death Discov 2019 1;5:110. Epub 2019 Jul 1.

3Research Section, Edward Hines, Jr. VA Hospital, Hines, Maywood, IL 60141 USA.

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http://dx.doi.org/10.1038/s41420-019-0189-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602934PMC
July 2019

Intra-Articular Biocompatibility of Multistranded, Long-Chain Polyethylene Suture Tape in a Canine ACL Model.

Authors:
Patrick A Smith Chantelle C Bozynski Keiichi Kuroki Sarah M Henrich Coen A Wijdicks James L Cook

J Knee Surg 2019 Jun 31;32(6):525-531. Epub 2018 May 31.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0038-1655765DOI Listing
June 2019

Incidence of Concurrent Peroneal Nerve Injury in Multiligament Knee Injuries and Outcomes after Knee Reconstruction.

Authors:
John R Worley Olubusola Brimmo Clayton W Nuelle James L Cook James P Stannard

J Knee Surg 2019 Jun 13;32(6):560-564. Epub 2018 Jun 13.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0038-1660512DOI Listing
June 2019

α5GABA subunit-containing receptors and sweetened alcohol cue-induced reinstatement and active sweetened alcohol self-administration in male rats.

Authors:
Cassie M Chandler Jaren Reeves-Darby Sherman A Jones J Abigail McDonald Guanguan Li Md T Rahman James M Cook Donna M Platt

Psychopharmacology (Berl) 2019 Jun 12;236(6):1797-1806. Epub 2019 Jan 12.

Graduate Program in Neuroscience, University of Mississippi Medical Center, Jackson, MS, 39216, USA.

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http://link.springer.com/10.1007/s00213-018-5163-6
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http://dx.doi.org/10.1007/s00213-018-5163-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606346PMC
June 2019

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Dietary Sodium, Potassium, and Blood Pressure in Normotensive Pregnant Women: the National Health and Nutrition Examination Survey.

Authors:
Abbi D Lane-Cordova Lara R Schneider William C Tucker James W Cook Sara Wilcox Jihong Liu

Appl Physiol Nutr Metab 2019 Jun 28. Epub 2019 Jun 28.

University of South Carolina at Columbia, Epidemiology and Biostatistics, Columbia, South Carolina, United States ;

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http://dx.doi.org/10.1139/apnm-2019-0186DOI Listing
June 2019

Evaluation of a Novel Degradable Synthetic Biomaterial Patch for Augmentation of Tendon Healing in a Large Animal Model.

Authors:
Wayne K Gersoff Chantelle C Bozynski Cristi R Cook Ferris M Pfeiffer Keiichi Kuroki James L Cook

J Knee Surg 2019 May 27;32(5):434-440. Epub 2018 Apr 27.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0038-1646930DOI Listing
May 2019

Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABA receptors.

Authors:
Dina Vasović Branka Divović Marco Treven Daniel E Knutson Friederike Steudle Petra Scholze Aleksandar Obradović Jure Fabjan Božidar Brković Werner Sieghart Margot Ernst James M Cook Miroslav M Savić

Eur J Pain 2019 05 4;23(5):973-984. Epub 2019 Feb 4.

Faculty of Pharmacy, Department of Pharmacology, University of Belgrade, Belgrade, Serbia.

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http://dx.doi.org/10.1002/ejp.1365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461498PMC
May 2019

Modulating native GABA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.

Authors:
Laura Kallay Havva Keskin Alexandra Ross Manali Rupji Olivia A Moody Xin Wang Guanguan Li Taukir Ahmed Farjana Rashid Michael Rajesh Stephen Kirsten A Cottrill T Austin Nuckols Maxwell Xu Deborah E Martinson Frank Tranghese Yanxin Pei James M Cook Jeanne Kowalski Michael D Taylor Andrew Jenkins Daniel A Pomeranz Krummel Soma Sengupta

J Neurooncol 2019 May 6;142(3):411-422. Epub 2019 Feb 6.

Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1007/s11060-019-03115-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478651PMC
May 2019

GABA Receptor Subtypes and the Abuse-Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators.

Authors:
Lais F Berro Daniela Rüedi-Bettschen Jemma E Cook Lalit K Golani Guanguan Li Rajwana Jahan Farjana Rashid James M Cook James K Rowlett Donna M Platt

Alcohol Clin Exp Res 2019 May 8;43(5):791-802. Epub 2019 Apr 8.

Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi.

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http://dx.doi.org/10.1111/acer.14000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601614PMC
May 2019

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders.

Authors:
Thomas D Prevot Guanguan Li James M Cook Etienne Sibille

ACS Chem Neurosci 2019 May 28;10(5):2088-2090. Epub 2019 Mar 28.

Campbell Family Mental Health Research Institute , Centre for Addiction and Mental Health , Toronto , ON M5T 1R8 , Canada.

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http://dx.doi.org/10.1021/acschemneuro.9b00148DOI Listing
May 2019

A Biomechanical Study of the Role of the Anterolateral Ligament and the Deep Iliotibial Band for Control of a Simulated Pivot Shift With Comparison of Minimally Invasive Extra-articular Anterolateral Tendon Graft Reconstruction Versus Modified Lemaire Reconstruction After Anterior Cruciate Ligament Reconstruction.

Authors:
Patrick A Smith Dimitri M Thomas Ryan J Pomajzl Jordan A Bley Ferris M Pfeiffer James L Cook

Arthroscopy 2019 May 26;35(5):1473-1483. Epub 2019 Mar 26.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, U.S.A.; Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri, U.S.A.

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http://dx.doi.org/10.1016/j.arthro.2018.11.011DOI Listing
May 2019

Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze.

Authors:
Polly F M Robinson Céline Pattaroni James Cook Lisa Gregory Aldara Martin Alonso Louise J Fleming Clare M Lloyd Andrew Bush Benjamin J Marsland Sejal Saglani

J Allergy Clin Immunol 2019 Apr 21;143(4):1607-1610.e3. Epub 2018 Dec 21.

National Heart and Lung Institute, Imperial College, London, United Kingdom; Paediatric Respiratory Department, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.12.985DOI Listing
April 2019

Incisional Negative Pressure Wound Therapy Devices Improve Short-Term Wound Complications, but Not Long-Term Infection Rate Following Hip and Knee Arthroplasty.

Authors:
James A Keeney James L Cook Stacee W Clawson Ajay Aggarwal James P Stannard

J Arthroplasty 2019 04 15;34(4):723-728. Epub 2018 Dec 15.

Department of Orthopaedic Surgery, University of Missouri, Columbia, MO.

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https://linkinghub.elsevier.com/retrieve/pii/S08835403183120
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http://dx.doi.org/10.1016/j.arth.2018.12.008DOI Listing
April 2019

Protein biomarkers in serum and urine for determining presence or absence of hip dysplasia in a canine model.

Authors:
Carin E Ahner Aaron M Stoker Chantelle C Bozynski Cristi R Cook Emily V Leary Keiichi Kuroki Carissa N Cruz James L Cook

J Orthop Res 2019 04 28;37(4):916-920. Epub 2019 Feb 28.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1002/jor.24242DOI Listing
April 2019

Fli-1 transcription factor regulates the expression of caspase-1 in lung pericytes.

Authors:
Pengfei Li Andrew J Goodwin James A Cook Perry V Halushka Xian K Zhang Hongkuan Fan

Mol Immunol 2019 04 8;108:1-7. Epub 2019 Feb 8.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, United States. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409192PMC
April 2019

Knee Ultrasonography to Determine Risk for Noncontact Injuries in Collegiate American Football Players.

Authors:
Ryan A Lewis Cristi R Cook Patrick A Smith James P Stannard Rex L Sharp Kyle M Blecha James L Cook

J Knee Surg 2019 Apr 8. Epub 2019 Apr 8.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0039-1683953DOI Listing
April 2019

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles.

Authors:
Thomas D Prevot Guanguan Li Aleksandra Vidojevic Keith A Misquitta Corey Fee Anja Santrac Daniel E Knutson Michael Rajesh Stephen Revathi Kodali Nicolas M Zahn Leggy A Arnold Petra Scholze Janet L Fisher Bojan D Marković Mounira Banasr James M Cook Miroslav Savic Etienne Sibille

Mol Neuropsychiatry 2019 Apr 23;5(2):84-97. Epub 2019 Jan 23.

Campbell Family Mental Health Research Institute of CAMH, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1159/000496086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528097PMC
April 2019

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Authors:
Anne E Justice Tugce Karaderi Heather M Highland Kristin L Young Mariaelisa Graff Yingchang Lu Valérie Turcot Paul L Auer Rebecca S Fine Xiuqing Guo Claudia Schurmann Adelheid Lempradl Eirini Marouli Anubha Mahajan Thomas W Winkler Adam E Locke Carolina Medina-Gomez Tõnu Esko Sailaja Vedantam Ayush Giri Ken Sin Lo Tamuno Alfred Poorva Mudgal Maggie C Y Ng Nancy L Heard-Costa Mary F Feitosa Alisa K Manning Sara M Willems Suthesh Sivapalaratnam Goncalo Abecasis Dewan S Alam Matthew Allison Philippe Amouyel Zorayr Arzumanyan Beverley Balkau Lisa Bastarache Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Erwin P Bottinger Donald W Bowden Ivan Brandslund Linda Broer Amber A Burt Adam S Butterworth Mark J Caulfield Giancarlo Cesana John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Francis S Collins James P Cook Amanda J Cox David S Crosslin John Danesh Paul I W de Bakker Simon de Denus Renée de Mutsert George Dedoussis Ellen W Demerath Joe G Dennis Josh C Denny Emanuele Di Angelantonio Marcus Dörr Fotios Drenos Marie-Pierre Dubé Alison M Dunning Douglas F Easton Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Myriam Fornage Caroline S Fox Paul W Franks Nele Friedrich Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Giorgia Girotto Mathias Gorski Harald Grallert Niels Grarup Megan L Grove Stefan Gustafsson Jeff Haessler Torben Hansen Andrew T Hattersley Caroline Hayward Iris M Heid Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Yi-Jen Hung Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Gail P Jarvik Yucheng Jia Torben Jørgensen Pekka Jousilahti Johanne M Justesen Bratati Kahali Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Peter Kovacs Bernhard K Krämer Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Wen-Jane Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Jian'an Luan Leo-Pekka Lyytikäinen Stuart MacGregor Reedik Mägi Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G D Masca Mark I McCarthy Karina Meidtner Evelin Mihailov Leena Moilanen Marie Moitry Dennis O Mook-Kanamori Anna Morgan Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Narisu Narisu Christopher P Nelson Matt Neville Ioanna Ntalla Jeffrey R O'Connell Katharine R Owen Oluf Pedersen Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Ailith Ewing Ozren Polasek Olli T Raitakari Asif Rasheed Chelsea K Raulerson Rainer Rauramaa Dermot F Reilly Alex P Reiner Paul M Ridker Manuel A Rivas Neil R Robertson Antonietta Robino Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo Segura-Lepe Xueling Sim Andrew J Slater Kerrin S Small Blair H Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Karin M A Swart Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Mina Torres Emmanouil Tsafantakis Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Cornelia M van Duijn Mauno Vanhala Rohit Varma Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao He Zheng Wei Zhou M Carola Zillikens Fernando Rivadeneira Ingrid B Borecki J Andrew Pospisilik Panos Deloukas Timothy M Frayling Guillaume Lettre Karen L Mohlke Jerome I Rotter Zoltán Kutalik Joel N Hirschhorn L Adrienne Cupples Ruth J F Loos Kari E North Cecilia M Lindgren

Nat Genet 2019 03 18;51(3):452-469. Epub 2019 Feb 18.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41588-018-0334-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560635PMC
March 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis.

Authors:
Joy N Jones Buie Yue Zhou Andrew J Goodwin James A Cook John Vournakis Marina Demcheva Ann-Marie Broome Suraj Dixit Perry V Halushka Hongkuan Fan

Inflammation 2019 Feb;42(1):170-184

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 173 Ashley Ave., MSC 908, CRI Room 610, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1007/s10753-018-0882-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380957PMC
February 2019

IRTA1 and MNDA Expression in Marginal Zone Lymphoma: Utility in Differential Diagnosis and Implications for Classification.

Authors:
Zhen Wang James R Cook

Am J Clin Pathol 2019 Feb;151(3):337-343

Department of Laboratory Medicine, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.

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https://academic.oup.com/ajcp/advance-article/doi/10.1093/aj
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February 2019

A novel GABA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.

Authors:
Gene T Yocum Jose F Perez-Zoghbi Jennifer Danielsson Aisha S Kuforiji Yi Zhang Guanguan Li M S Rashid Roni Revathi Kodali Douglas C Stafford Leggy A Arnold James M Cook Charles W Emala

Am J Physiol Lung Cell Mol Physiol 2019 Feb 29;316(2):L385-L390. Epub 2018 Nov 29.

Department of Anesthesiology, Vagelos College of Physicians and Surgeons, Columbia University , New York, New York.

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http://dx.doi.org/10.1152/ajplung.00356.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397346PMC
February 2019

Histologic assessment of ligament vascularity and synovitis in dogs with cranial cruciate ligament disease.

Authors:
Keiichi Kuroki Ned Williams Hitoshi Ikeda Chantelle C Bozynski Emily Leary James L Cook

Am J Vet Res 2019 Feb;80(2):152-158

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http://dx.doi.org/10.2460/ajvr.80.2.152DOI Listing
February 2019

Biomechanical Properties of Bioabsorbable Fixation for Osteochondral Shell Allografts.

Authors:
Dimitri M Thomas James P Stannard Ferris M Pfeiffer James L Cook

J Knee Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Orthopaedic Surgery, Missouri Orthopaedic Institute, University of Missouri Columbia, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0039-1677837DOI Listing
February 2019

Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury.

Authors:
Yue Zhou Pengfei Li Andrew J Goodwin James A Cook Perry V Halushka Eugene Chang Basilia Zingarelli Hongkuan Fan

Crit Care 2019 02 13;23(1):44. Epub 2019 Feb 13.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 173 Ashley Ave., MSC 908, CRI Room 610, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1186/s13054-019-2339-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373158PMC
February 2019

Comparison of Techniques for Preimplantation Treatment of Osteochondral Allograft Bone.

Authors:
Charles A Baumann John R Baumann Chantelle C Bozynski Aaron M Stoker James P Stannard James L Cook

J Knee Surg 2019 Jan 7;32(1):97-104. Epub 2018 Mar 7.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1636834
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January 2019

Cooled Radio Frequency Ablation for the Treatment of Osteoarthritis-Related Knee Pain: Evidence, Indications, and Outcomes.

Authors:
Lasun O Oladeji James L Cook

J Knee Surg 2019 Jan 5;32(1):65-71. Epub 2018 Nov 5.

Missouri Orthopaedic Institute, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0038-1675418DOI Listing
January 2019

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

Authors:
Ayush Giri Jacklyn N Hellwege Jacob M Keaton Jihwan Park Chengxiang Qiu Helen R Warren Eric S Torstenson Csaba P Kovesdy Yan V Sun Otis D Wilson Cassianne Robinson-Cohen Christianne L Roumie Cecilia P Chung Kelly A Birdwell Scott M Damrauer Scott L DuVall Derek Klarin Kelly Cho Yu Wang Evangelos Evangelou Claudia P Cabrera Louise V Wain Rojesh Shrestha Brian S Mautz Elvis A Akwo Muralidharan Sargurupremraj Stéphanie Debette Michael Boehnke Laura J Scott Jian'an Luan Jing-Hua Zhao Sara M Willems Sébastien Thériault Nabi Shah Christopher Oldmeadow Peter Almgren Ruifang Li-Gao Niek Verweij Thibaud S Boutin Massimo Mangino Ioanna Ntalla Elena Feofanova Praveen Surendran James P Cook Savita Karthikeyan Najim Lahrouchi Chunyu Liu Nuno Sepúlveda Tom G Richardson Aldi Kraja Philippe Amouyel Martin Farrall Neil R Poulter Markku Laakso Eleftheria Zeggini Peter Sever Robert A Scott Claudia Langenberg Nicholas J Wareham David Conen Colin Neil Alexander Palmer John Attia Daniel I Chasman Paul M Ridker Olle Melander Dennis Owen Mook-Kanamori Pim van der Harst Francesco Cucca David Schlessinger Caroline Hayward Tim D Spector Marjo-Riitta Jarvelin Branwen J Hennig Nicholas J Timpson Wei-Qi Wei Joshua C Smith Yaomin Xu Michael E Matheny Edward E Siew Cecilia Lindgren Karl-Heinz Herzig George Dedoussis Joshua C Denny Bruce M Psaty Joanna M M Howson Patricia B Munroe Christopher Newton-Cheh Mark J Caulfield Paul Elliott J Michael Gaziano John Concato Peter W F Wilson Philip S Tsao Digna R Velez Edwards Katalin Susztak Christopher J O'Donnell Adriana M Hung Todd L Edwards

Nat Genet 2019 01 21;51(1):51-62. Epub 2018 Dec 21.

Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.

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http://www.nature.com/articles/s41588-018-0303-9
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365102PMC
January 2019

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Authors:
Andrew P Morris Thu H Le Haojia Wu Artur Akbarov Peter J van der Most Gibran Hemani George Davey Smith Anubha Mahajan Kyle J Gaulton Girish N Nadkarni Adan Valladares-Salgado Niels Wacher-Rodarte Josyf C Mychaleckyj Nicole D Dueker Xiuqing Guo Yang Hai Jeffrey Haessler Yoichiro Kamatani Adrienne M Stilp Gu Zhu James P Cook Johan Ärnlöv Susan H Blanton Martin H de Borst Erwin P Bottinger Thomas A Buchanan Sylvia Cechova Fadi J Charchar Pei-Lun Chu Jeffrey Damman James Eales Ali G Gharavi Vilmantas Giedraitis Andrew C Heath Eli Ipp Krzysztof Kiryluk Holly J Kramer Michiaki Kubo Anders Larsson Cecilia M Lindgren Yingchang Lu Pamela A F Madden Grant W Montgomery George J Papanicolaou Leslie J Raffel Ralph L Sacco Elena Sanchez Holger Stark Johan Sundstrom Kent D Taylor Anny H Xiang Aleksandra Zivkovic Lars Lind Erik Ingelsson Nicholas G Martin John B Whitfield Jianwen Cai Cathy C Laurie Yukinori Okada Koichi Matsuda Charles Kooperberg Yii-Der Ida Chen Tatjana Rundek Stephen S Rich Ruth J F Loos Esteban J Parra Miguel Cruz Jerome I Rotter Harold Snieder Maciej Tomaszewski Benjamin D Humphreys Nora Franceschini

Nat Commun 2019 01 3;10(1):29. Epub 2019 Jan 3.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27516-8050, USA.

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http://www.nature.com/articles/s41467-018-07867-7
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318312PMC
January 2019

Alternative Therapies for Knee Pain.

Authors:
James L Cook

J Knee Surg 2019 Jan 4;32(1). Epub 2019 Jan 4.

Missouri Orthopaedic Institute, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1055/s-0038-1669910DOI Listing
January 2019

Repeated, within-session resurgence.

Authors:
James E Cook Kennon A Lattal

J Exp Anal Behav 2019 01;111(1):28-47

West Virginia University.

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http://dx.doi.org/10.1002/jeab.496DOI Listing
January 2019

Zolpidem Activation of Alpha 1-Containing GABA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons.

Authors:
Elena Neumann Uwe Rudolph Daniel E Knutson Guanguan Li James M Cook Harald Hentschke Bernd Antkowiak Berthold Drexler

Front Pharmacol 2018 9;9:1523. Epub 2019 Jan 9.

Experimental Anesthesiology Section, Department of Anesthesiology and Intensive Care, Eberhard Karls Universität Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fphar.2018.01523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333667PMC
January 2019

Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?

Authors:
Tessa Swanton James Cook James A Beswick Sally Freeman Catherine B Lawrence David Brough

SLAS Discov 2018 12 3;23(10):991-1017. Epub 2018 Jul 3.

1 Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1177/2472555218786210DOI Listing
December 2018

In Vivo Toxicity of Local Anesthetics and Corticosteroids on Supraspinatus Tenocyte Cell Viability and Metabolism.

Authors:
Clayton W Nuelle Cristi R Cook Aaron M Stoker James L Cook Seth L Sherman

Iowa Orthop J 2018 ;38:107-112

Department of Orthopaedic Surgery, University of Missouri, Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047373PMC
December 2018

Natural Environments Near Schools: Potential Benefits for Socio-Emotional and Behavioral Development in Early Childhood.

Authors:
J Taylor Scott Ryan P Kilmer Chuang Wang James R Cook Mason G Haber

Am J Community Psychol 2018 12 17;62(3-4):419-432. Epub 2018 Sep 17.

University of North Carolina at Charlotte, Charlotte, NC, USA.

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http://doi.wiley.com/10.1002/ajcp.12272
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December 2018

Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis.

Authors:
Pengfei Li Yue Zhou Andrew J Goodwin James A Cook Perry V Halushka Xian K Zhang Carole L Wilson Lynn M Schnapp Basilia Zingarelli Hongkuan Fan

J Infect Dis 2018 11;218(12):1995-2005

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston.

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http://dx.doi.org/10.1093/infdis/jiy451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217724PMC
November 2018

Spectroscopic analysis of chlamydial major outer membrane protein in support of structure elucidation.

Authors:
Robert W Hepler Debbie D Nahas Bob Lucas Robin Kaufhold Jessica A Flynn Jennifer D Galli Ryan Swoyer James M Wagner Amy S Espeseth Joseph G Joyce James C Cook Eberhard Durr

Protein Sci 2018 11;27(11):1923-1941

Infectious Diseases and Vaccines Discovery, MRL, Merck & Co., Inc., Kenilworth, New Jersey.

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http://doi.wiley.com/10.1002/pro.3501
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201732PMC
November 2018

Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens.

Authors:
Anja Mottok George Wright Andreas Rosenwald German Ott Colleen Ramsower Elias Campo Rita M Braziel Jan Delabie Dennis D Weisenburger Joo Y Song Wing C Chan James R Cook Kai Fu Tim Greiner Erlend Smeland Harald Holte Kerry J Savage Betty J Glinsmann-Gibson Randy D Gascoyne Louis M Staudt Elaine S Jaffe Joseph M Connors David W Scott Christian Steidl Lisa M Rimsza

Blood 2018 11 26;132(22):2401-2405. Epub 2018 Sep 26.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.1182/blood-2018-05-851154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265647PMC
November 2018

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

Authors:
Anubha Mahajan Daniel Taliun Matthias Thurner Neil R Robertson Jason M Torres N William Rayner Anthony J Payne Valgerdur Steinthorsdottir Robert A Scott Niels Grarup James P Cook Ellen M Schmidt Matthias Wuttke Chloé Sarnowski Reedik Mägi Jana Nano Christian Gieger Stella Trompet Cécile Lecoeur Michael H Preuss Bram Peter Prins Xiuqing Guo Lawrence F Bielak Jennifer E Below Donald W Bowden John Campbell Chambers Young Jin Kim Maggie C Y Ng Lauren E Petty Xueling Sim Weihua Zhang Amanda J Bennett Jette Bork-Jensen Chad M Brummett Mickaël Canouil Kai-Uwe Ec Kardt Krista Fischer Sharon L R Kardia Florian Kronenberg Kristi Läll Ching-Ti Liu Adam E Locke Jian'an Luan Ioanna Ntalla Vibe Nylander Sebastian Schönherr Claudia Schurmann Loïc Yengo Erwin P Bottinger Ivan Brandslund Cramer Christensen George Dedoussis Jose C Florez Ian Ford Oscar H Franco Timothy M Frayling Vilmantas Giedraitis Sophie Hackinger Andrew T Hattersley Christian Herder M Arfan Ikram Martin Ingelsson Marit E Jørgensen Torben Jørgensen Jennifer Kriebel Johanna Kuusisto Symen Ligthart Cecilia M Lindgren Allan Linneberg Valeriya Lyssenko Vasiliki Mamakou Thomas Meitinger Karen L Mohlke Andrew D Morris Girish Nadkarni James S Pankow Annette Peters Naveed Sattar Alena Stančáková Konstantin Strauch Kent D Taylor Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Jaakko Tuomilehto Daniel R Witte Josée Dupuis Patricia A Peyser Eleftheria Zeggini Ruth J F Loos Philippe Froguel Erik Ingelsson Lars Lind Leif Groop Markku Laakso Francis S Collins J Wouter Jukema Colin N A Palmer Harald Grallert Andres Metspalu Abbas Dehghan Anna Köttgen Goncalo R Abecasis James B Meigs Jerome I Rotter Jonathan Marchini Oluf Pedersen Torben Hansen Claudia Langenberg Nicholas J Wareham Kari Stefansson Anna L Gloyn Andrew P Morris Michael Boehnke Mark I McCarthy

Nat Genet 2018 11 8;50(11):1505-1513. Epub 2018 Oct 8.

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://www.nature.com/articles/s41588-018-0241-6
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287706PMC
November 2018

Metabolic responses of meniscal explants to injury and inflammation ex vivo.

Authors:
Alex E Cook Aaron M Stoker Emily V Leary Ferris M Pfeiffer James L Cook

J Orthop Res 2018 10 13;36(10):2657-2663. Epub 2018 Jun 13.

Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1002/jor.24045DOI Listing
October 2018

Subchondroplasty for the treatment of post-traumatic bone marrow lesions of the medial femoral condyle in a pre-clinical canine model.

Authors:
Olubusola A Brimmo Chantelle C Bozynski Cristi R Cook Keiichi Kuroki Seth L Sherman Ferris M Pfeiffer Aaron M Stoker James L Cook

J Orthop Res 2018 10 13;36(10):2709-2717. Epub 2018 Jun 13.

Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri.

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http://dx.doi.org/10.1002/jor.24046DOI Listing
October 2018

Elevated atmospheric carbon dioxide concentrations promote ant tending of aphids.

Authors:
Jenni M M Kremer Sabine S Nooten James M Cook James M W Ryalls Craig V M Barton Scott N Johnson

J Anim Ecol 2018 09 17;87(5):1475-1483. Epub 2018 May 17.

Hawkesbury Institute for the Environment, Western Sydney University, Penrith, New South Wales, Australia.

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http://dx.doi.org/10.1111/1365-2656.12842DOI Listing
September 2018

The α6 subunit-containing GABA receptor: A novel drug target for inhibition of trigeminal activation.

Authors:
Pi-Chuan Fan Tzu-Hsuan Lai Chia Chun Hor Ming Tatt Lee Pokai Huang Werner Sieghart Margot Ernst Daniel E Knutson James Cook Lih-Chu Chiou

Neuropharmacology 2018 09 21;140:1-13. Epub 2018 Jul 21.

Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan; Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan; Clinical Center for Neuroscience and Behavioral, National Taiwan University Hospital, Taipei, 10002, Taiwan; Graduate Institute of Acupuncture Sciences, China Medical University, Taichung, 404, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180911PMC
September 2018

OSTEOCHONDRAL AUTOGRAFT TRANSFER FOR TREATMENT OF STIFLE OSTEOCHONDRITIS DISSECANS IN TWO RELATED SNOW LEOPARDS ( PANTHERA UNCIA).

Authors:
Gail L Huckins Sathya K Chinnadurai Marina Ivančić Jonathan Bergmann Julie A Balko Copper Aitken-Palmer Michael J Adkesson Jennifer N Langan James L Cook

J Zoo Wildl Med 2018 Sep;49(3):788-793

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http://dx.doi.org/10.1638/2017-0229.1DOI Listing
September 2018

PIDD-dependent activation of caspase-2-mediated mitochondrial injury in E1A-induced cellular sensitivity to macrophage nitric oxide-induced apoptosis.

Authors:
Jay R Radke Iris Figueroa John M Routes James L Cook

Cell Death Discov 2018 12;4:35. Epub 2018 Sep 12.

1Division of Infectious Diseases, Department of Medicine, and the Infectious Diseases and Immunology Research Institute, Loyola University Chicago-Stritch School of Medicine, Maywood, IL 60153 USA.

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http://dx.doi.org/10.1038/s41420-018-0100-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135794PMC
September 2018

Different Benzodiazepines Bind with Distinct Binding Modes to GABA Receptors.

Authors:
Alshaimaa A Elgarf David C B Siebert Friederike Steudle Angelika Draxler Guanguan Li Shengming Huang James M Cook Margot Ernst Petra Scholze

ACS Chem Biol 2018 08 23;13(8):2033-2039. Epub 2018 Jul 23.

Department of Pathobiology of the Nervous System, Center for Brain Research , Medical University of Vienna , 1090 Vienna , Austria.

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http://dx.doi.org/10.1021/acschembio.8b00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102643PMC
August 2018

Attaining in vivo selectivity of positive modulation of α3βγ2 GABA receptors in rats: A hard task!

Authors:
Bojan Batinić Tamara Stanković Michael Rajesh Stephen Revathi Kodali Veera V Tiruveedhula Guanguan Li Petra Scholze Bojan D Marković Aleksandar Lj Obradović Margot Ernst James M Cook Miroslav M Savić

Eur Neuropsychopharmacol 2018 08 19;28(8):903-914. Epub 2018 Jun 19.

Department of Pharmacology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2018.05.014DOI Listing
August 2018

Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.

Authors:
Angela N Duke Zhiqiang Meng Donna M Platt John R Atack Gerard R Dawson David S Reynolds V V N Phani Babu Tiruveedhula Guanguan Li Michael Rajesh Stephen Werner Sieghart James M Cook James K Rowlett

J Pharmacol Exp Ther 2018 07 2;366(1):145-157. Epub 2018 May 2.

New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts (A.N.D., Z.M., D.M.P., J.K.R.); Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi (D.M.P., J.K.R.); Medicines Discovery Institute, Cardiff University, Cardiff, Wales, United Kingdom (J.R.A.); P1Vital, University of Oxford, Warneford Hospital, Headington, Oxford, United Kingdom (G.R.D.); Alzheimer's Research UK, Granta Park, Great Abington, Cambridge, United Kingdom (D.S.R.); Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin (V.V.N.P.B.T., G.L., M.R.S., J.M.C.); and Division of Biochemistry and Molecular Biology, Center for Brain Research, Medical University of Vienna, Vienna, Austria (W.S.)

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http://dx.doi.org/10.1124/jpet.118.249250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988000PMC
July 2018

Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms.

Authors:
Hélène Fe Gleitz Ai Yin Liao James R Cook Samuel F Rowlston Gabriella Ma Forte Zelpha D'Souza Claire O'Leary Rebecca J Holley Brian W Bigger

EMBO Mol Med 2018 07;10(7)

Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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http://dx.doi.org/10.15252/emmm.201708730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034129PMC
July 2018

The Use of Fluoroscopy During Direct Anterior Hip Arthroplasty: Powerful or Misleading?

Authors:
Christopher R James Blake E Peterson Julia R Crim James L Cook Brett D Crist

J Arthroplasty 2018 06 1;33(6):1775-1779. Epub 2018 Feb 1.

Department of Orthopaedic Surgery, University of Missouri, Columbia, MO.

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http://dx.doi.org/10.1016/j.arth.2018.01.040DOI Listing
June 2018

Cerebellar α -subunit-containing GABA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

Authors:
Lih-Chu Chiou Hsin-Jung Lee Margot Ernst Wei-Jan Huang Jui-Feng Chou Hon-Lie Chen Akihiro Mouri Liang-Chieh Chen Marco Treven Takayoshi Mamiya Pi-Chuan Fan Daniel E Knutson Chris Witzigmann James Cook Werner Sieghart Toshitaka Nabeshima

Br J Pharmacol 2018 06 10;175(12):2414-2427. Epub 2018 May 10.

Department of Chemical Pharmacology, Faculty of Pharmacy, Meijo University, Nagoya, Japan

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http://dx.doi.org/10.1111/bph.14198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980635PMC
June 2018

Human adenovirus infections: update and consideration of mechanisms of viral persistence.

Authors:
Jay R Radke James L Cook

Curr Opin Infect Dis 2018 06;31(3):251-256

Loyola University Chicago - Stritch School of Medicine and Edward Hines, Jr. Veterans Administration Hospital, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/QCO.0000000000000451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367924PMC
June 2018

Assessment of Reamer Irrigator Aspirator System (RIA) filtrate for its osteoinductive potential in a validated animal model.

Authors:
Alex R Wessel Brett D Crist James P Stannard Gregory J Della Rocca Aaron M Stoker Chantelle C Bozynski Cristi R Cook Keiichi Kuroki Carin E Ahner James L Cook

Injury 2018 Jun 17;49(6):1046-1051. Epub 2018 Apr 17.

Department of Orthopaedic Surgery, University of Missouri, Columbia, USA; Thompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, USA. Electronic address:

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http://dx.doi.org/10.1016/j.injury.2018.04.010DOI Listing
June 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Development of a Behavioral Health Stigma Measure and Application of Machine Learning for Classification.

Authors:
Farah Tokmic Mirsad Hadzikadic James R Cook Oleg V Tcheremissine

Innov Clin Neurosci 2018 Jun;15(5-6):34-42

Drs. Tokmic and Hadzikadic are with the Department of Software & Information Systems at the University of North Carolina, in Charlotte, North Carolina.

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June 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):765-766

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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May 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):766-767

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-018-0082-3DOI Listing
May 2018

A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABA Receptors in the Lung.

Authors:
Gloria S Forkuo Amanda N Nieman Revathi Kodali Nicolas M Zahn Guanguan Li M S Rashid Roni Michael Rajesh Stephen Ted W Harris Rajwana Jahan Margaret L Guthrie Olivia B Yu Janet L Fisher Gene T Yocum Charles W Emala Douglas A Steeber Douglas C Stafford James M Cook Leggy A Arnold

Mol Pharm 2018 05 2;15(5):1766-1777. Epub 2018 Apr 2.

Department of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , Milwaukee , Wisconsin 53211 , United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b01013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954213PMC
May 2018

Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis.

Authors:
Yue Zhou Pengfei Li Andrew J Goodwin James A Cook Perry V Halushka Eugene Chang Hongkuan Fan

Mol Ther 2018 05 27;26(5):1375-1384. Epub 2018 Feb 27.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016183007
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http://dx.doi.org/10.1016/j.ymthe.2018.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993985PMC
May 2018

Engineered Healing of Avascular Meniscus Tears by Stem Cell Recruitment.

Authors:
Solaiman Tarafder Joseph Gulko Kun Hee Sim Jian Yang James L Cook Chang H Lee

Sci Rep 2018 05 25;8(1):8150. Epub 2018 May 25.

Regenerative Engineering Laboratory Columbia University Medical Center, 630W. 168 St. - VC12-230, New York, NY, 10032, USA.

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http://www.nature.com/articles/s41598-018-26545-8
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970239PMC
May 2018

Conserved community structure and simultaneous divergence events in the fig wasps associated with Ficus benjamina in Australia and China.

Authors:
Clive T Darwell Simon T Segar James M Cook

BMC Ecol 2018 04 3;18(1):13. Epub 2018 Apr 3.

School of Biological Sciences, University of Reading, Reading, RG6 6AS, UK.

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http://dx.doi.org/10.1186/s12898-018-0167-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883542PMC
April 2018

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Authors:
Anubha Mahajan Jennifer Wessel Sara M Willems Wei Zhao Neil R Robertson Audrey Y Chu Wei Gan Hidetoshi Kitajima Daniel Taliun N William Rayner Xiuqing Guo Yingchang Lu Man Li Richard A Jensen Yao Hu Shaofeng Huo Kurt K Lohman Weihua Zhang James P Cook Bram Peter Prins Jason Flannick Niels Grarup Vassily Vladimirovich Trubetskoy Jasmina Kravic Young Jin Kim Denis V Rybin Hanieh Yaghootkar Martina Müller-Nurasyid Karina Meidtner Ruifang Li-Gao Tibor V Varga Jonathan Marten Jin Li Albert Vernon Smith Ping An Symen Ligthart Stefan Gustafsson Giovanni Malerba Ayse Demirkan Juan Fernandez Tajes Valgerdur Steinthorsdottir Matthias Wuttke Cécile Lecoeur Michael Preuss Lawrence F Bielak Marielisa Graff Heather M Highland Anne E Justice Dajiang J Liu Eirini Marouli Gina Marie Peloso Helen R Warren Saima Afaq Shoaib Afzal Emma Ahlqvist Peter Almgren Najaf Amin Lia B Bang Alain G Bertoni Cristina Bombieri Jette Bork-Jensen Ivan Brandslund Jennifer A Brody Noël P Burtt Mickaël Canouil Yii-Der Ida Chen Yoon Shin Cho Cramer Christensen Sophie V Eastwood Kai-Uwe Eckardt Krista Fischer Giovanni Gambaro Vilmantas Giedraitis Megan L Grove Hugoline G de Haan Sophie Hackinger Yang Hai Sohee Han Anne Tybjærg-Hansen Marie-France Hivert Bo Isomaa Susanne Jäger Marit E Jørgensen Torben Jørgensen Annemari Käräjämäki Bong-Jo Kim Sung Soo Kim Heikki A Koistinen Peter Kovacs Jennifer Kriebel Florian Kronenberg Kristi Läll Leslie A Lange Jung-Jin Lee Benjamin Lehne Huaixing Li Keng-Hung Lin Allan Linneberg Ching-Ti Liu Jun Liu Marie Loh Reedik Mägi Vasiliki Mamakou Roberta McKean-Cowdin Girish Nadkarni Matt Neville Sune F Nielsen Ioanna Ntalla Patricia A Peyser Wolfgang Rathmann Kenneth Rice Stephen S Rich Line Rode Olov Rolandsson Sebastian Schönherr Elizabeth Selvin Kerrin S Small Alena Stančáková Praveen Surendran Kent D Taylor Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Adrienne Tin Anke Tönjes Anette Varbo Daniel R Witte Andrew R Wood Pranav Yajnik Jie Yao Loïc Yengo Robin Young Philippe Amouyel Heiner Boeing Eric Boerwinkle Erwin P Bottinger Rajiv Chowdhury Francis S Collins George Dedoussis Abbas Dehghan Panos Deloukas Marco M Ferrario Jean Ferrières Jose C Florez Philippe Frossard Vilmundur Gudnason Tamara B Harris Susan R Heckbert Joanna M M Howson Martin Ingelsson Sekar Kathiresan Frank Kee Johanna Kuusisto Claudia Langenberg Lenore J Launer Cecilia M Lindgren Satu Männistö Thomas Meitinger Olle Melander Karen L Mohlke Marie Moitry Andrew D Morris Alison D Murray Renée de Mutsert Marju Orho-Melander Katharine R Owen Markus Perola Annette Peters Michael A Province Asif Rasheed Paul M Ridker Fernando Rivadineira Frits R Rosendaal Anders H Rosengren Veikko Salomaa Wayne H-H Sheu Rob Sladek Blair H Smith Konstantin Strauch André G Uitterlinden Rohit Varma Cristen J Willer Matthias Blüher Adam S Butterworth John Campbell Chambers Daniel I Chasman John Danesh Cornelia van Duijn Josée Dupuis Oscar H Franco Paul W Franks Philippe Froguel Harald Grallert Leif Groop Bok-Ghee Han Torben Hansen Andrew T Hattersley Caroline Hayward Erik Ingelsson Sharon L R Kardia Fredrik Karpe Jaspal Singh Kooner Anna Köttgen Kari Kuulasmaa Markku Laakso Xu Lin Lars Lind Yongmei Liu Ruth J F Loos Jonathan Marchini Andres Metspalu Dennis Mook-Kanamori Børge G Nordestgaard Colin N A Palmer James S Pankow Oluf Pedersen Bruce M Psaty Rainer Rauramaa Naveed Sattar Matthias B Schulze Nicole Soranzo Timothy D Spector Kari Stefansson Michael Stumvoll Unnur Thorsteinsdottir Tiinamaija Tuomi Jaakko Tuomilehto Nicholas J Wareham James G Wilson Eleftheria Zeggini Robert A Scott Inês Barroso Timothy M Frayling Mark O Goodarzi James B Meigs Michael Boehnke Danish Saleheen Andrew P Morris Jerome I Rotter Mark I McCarthy

Nat Genet 2018 04 9;50(4):559-571. Epub 2018 Apr 9.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41588-018-0084-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898373PMC
April 2018

The Pathobiology of the Meniscus: A Comparison Between the Human and Dog.

Authors:
Olga Krupkova Lucas Smolders Karin Wuertz-Kozak James Cook Antonio Pozzi

Front Vet Sci 2018 16;5:73. Epub 2018 Apr 16.

Small Animals Surgery, Tierspital, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fvets.2018.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911564PMC
April 2018

Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability.

Authors:
Daniel E Knutson Revathi Kodali Branka Divović Marco Treven Michael R Stephen Nicolas M Zahn Vladimir Dobričić Alec T Huber Matheus A Meirelles Ranjit S Verma Laurin Wimmer Christopher Witzigmann Leggy A Arnold Lih-Chu Chiou Margot Ernst Marko D Mihovilovic Miroslav M Savić Werner Sieghart James M Cook

J Med Chem 2018 03 6;61(6):2422-2446. Epub 2018 Mar 6.

Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery , University of Wisconsin-Milwaukee , 3210 N. Cramer St. , Milwaukee , Wisconsin 53211 , United States.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01664DOI Listing
March 2018

Use of a Novel Magnesium-Based Resorbable Bone Cement for Augmenting Anchor and Tendon Fixation.

Authors:
Brandon L Roller Keiichi Kuroki Chantelle C Bozynski Ferris M Pfeiffer James L Cook

Am J Orthop (Belle Mead NJ) 2018 Feb;47(2)

Wake Forest Baptist Medical Center, Winston-Salem, NC.

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https://www.amjorthopedics.com/article/use-novel-magnesium-b
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February 2018