Publications by authors named "James C Fang"

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Cardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study.
Circ Cardiovasc Imaging 2018 Apr;11(4):e007117
Utah Transplantation Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program: University of Utah Health Sciences Center, Intermountain Medical Center, and Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah (M.J.B., A.K., O.W.-P., I.T., J.S., W.X., J.W.-P., A.C., J.N.-N., J.C.F., A.G.K., B.D.H., C.H.S., S.G.D.); Heart Failure and Transplant Unit, Onassis Cardiac Surgery Center, Athens, Greece (M.J.B., S.N.A.); and Department of Cardiology, Leiden University Medical Center, Netherlands (J.J.B.); 3rd Department of Cardiology, National and Kapodistrian University of Athens , Athens, Greece (S.G.D.).

When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation.
Circ Heart Fail 2018 Apr;11(4):e005116
Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Aurora (L.A.A.). Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego (E.D.A.). l'Institut del Cor, Hospital Universitari Germans Trias i Pujol, Badalona, Spain (A.B.-G.). Temple Heart and Vascular Institute, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (M.A.B.-B.). Division of Cardiology, Department of Medicine, University of Pennsylvania, Philadelphia (J.A.C.). Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (B.L.C., C.Y.H.). Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City (J.C.F.). Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark (F.G.). The Cardiovascular Center, Tufts Medical Center, Boston, MA (N.K.K.). Sarver Heart Center, University of Arizona, Tucson (J.L.C., S.E.K., N.K.S.). Section of Advanced Heart Failure and Mechanical Circulatory Support, UMass Memorial Medical Center, Worcester, MA (R.D.K.). Section of Advanced Heart Failure and Transplant Cardiology, Henry Ford Hospital, Detroit, MI (D.E.L.). Department of Medicine, Minneapolis VA Health Care System and University of Minnesota, Minneapolis (O.V.).


Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma.
Circ Heart Fail 2018 Mar;11(3):e004408
From the Division of Cardiovascular Medicine (A.B.C., J.C.F.) and Division of Oncology (N.A.), Department of Medicine, University of Utah, Salt Lake City; Department of Biostatistics, Epidemiology and Informatics (R.A.H., B.K.), Division of Cardiology (J.A.C., D.H., A.M.S., T.P., V.E., B.K.), Division of Hematology and Oncology (S.K., N.B.H., V.N.), and Division of Nephrology (R.T.), Department of Medicine, and Abramson Cancer Center (S.K., N.B.H., V.N., B.K.), University of Pennsylvania, Philadelphia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY (I.P.); Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison (S.E.); Division of Cardiovascular Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH (C.E.); Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (M.G.); and Division of Cardiology, Department of Medicine, Washington University in St Louis, MO (D.L.).

Racial Differences in Characteristics and Outcomes of Patients With Heart Failure and Preserved Ejection Fraction in the Treatment of Preserved Cardiac Function Heart Failure Trial.
Circ Heart Fail 2018 Mar;11(3):e004457
From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (E.F.L., B.C., A.M.S., J.L., A.S.D., S.D.S., M.A.P.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S.); Veterans Affairs Medical Center Minneapolis, Minnesota (I.A.); University of Minnesota Medical School, Minneapolis (I.A.); Veterans Affairs Medical Center at San Diego, CA (I.A.); Montreal Heart Institute, Quebec, Canada (J.L.R., E.O.); Department of Medicine, Sarver Heart Center, University of Arizona, Tucson (N.K.S.); Division of Cardiology, University of Utah, Salt Lake City (J.C.F.); Department of Medicine, Howard University College of Medicine, Washington, DC (T.M.R.); Division of Cardiology, New York Methodist Hospital, Brooklyn (J.F.H.); Division of Cardiology, University of Illinois at Chicago (T.D.S.); National Heart, Lung, and Blood Institute, Bethesda, MD (R.B.); and University of Michigan School of Medicine, Ann Arbor (B.P.).

Clinical and histopathological effects of heart failure drug therapy in advanced heart failure patients on chronic mechanical circulatory support.
Eur J Heart Fail 2018 Jan 1;20(1):164-174. Epub 2017 Nov 1.
Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program, Divisions of Cardiovascular Medicine and Cardiovascular Surgery, University of Utah Health Sciences Center, Salt Lake VA Medical Center, Intermountain Medical Center, Salt Lake City, UT, USA.


Physical Activity and Prognosis in the TOPCAT Trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist).
Circulation 2017 Sep 21;136(11):982-992. Epub 2017 Jun 21.
From Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (S.M.H., B.C., A.M.S., E.F.L., M.A.P., S.D.S.); Department of Cardiology, VA Medical Center and Division of Cardiovascular Medicine, University of Minnesota, Minneapolis (I.A.); Cardiology Division, Northwestern University, Chicago, IL (S.J.S.); Division of Cardiology, University of Arizona, Tucson (N.K.S.); Division of Cardiovascular Medicine, University of Utah, Salt Lake City (J.D.F.); and Cardiovascular Medicine Division, University of Michigan School of Medicine, Ann Arbor (B.P.).


Association of recipient age and causes of heart transplant mortality: Implications for personalization of post-transplant management-An analysis of the International Society for Heart and Lung Transplantation Registry.
J Heart Lung Transplant 2017 Apr 20;36(4):407-417. Epub 2016 Aug 20.
Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, University of Utah Health Center and Veterans Affairs Medical CentePlease check the following authors groups Abdallah G. Kfoury, Stavros G. Drakos, Craig H. Selzman affilation citation is missing.-->r, Intermountain Medical Center, Salt Lake City, Utah. Electronic address:

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.
Am J Cardiol 2016 Dec 15;118(12):1855-1860. Epub 2016 Sep 15.
Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.


Cardiac Recovery During Long-Term Left Ventricular Assist Device Support.
J Am Coll Cardiol 2016 Oct;68(14):1540-53
Utah Cardiac Recovery Program, Salt Lake City, Utah; Veterans Affairs Medical Center, Salt Lake City, Utah; Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah. Electronic address:

Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical Unloading.
J Am Coll Cardiol 2016 Oct;68(16):1741-1752
Utah Transplantation Affiliated Hospitals Cardiac Transplant Program, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah; University of Utah Molecular Medicine Program, Salt Lake City, Utah. Electronic address:

Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning.
JACC Basic Transl Sci 2016 Oct 31;1(6):432-444. Epub 2016 Oct 31.
Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah.

Immunologic effects of continuous-flow left ventricular assist devices before and after heart transplant.
J Heart Lung Transplant 2016 Aug 6;35(8):1024-30. Epub 2016 May 6.
Division of Cardiovascular Disease, University of Utah Health Sciences Center, Salt Lake City, Utah; George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah; Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah.

Exertional Angina Due To Fused Aortic Bioprosthesis During Left Ventricular Assist Device Support: Two Cases and Review of the Literature.
ASAIO J 2017 Jan/Feb;63(1):e6-e9
From the Divisions of *Cardiovascular Medicine and †Cardiothoracic Surgery, Cardiac Mechanical Support Program; University of Utah, Salt Lake City, Utah.


2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial Infarction: An update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.
Catheter Cardiovasc Interv 2016 May;87(6):1001-19
Former Task Force member; current member during the writing effort.

Prognostic Relevance of Left Atrial Dysfunction in Heart Failure With Preserved Ejection Fraction.
Circ Heart Fail 2016 Apr;9(4):e002763
From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (A.B.S.S., G.Q.R., B.C., S.D.S., A.M.S.); Cardiology Division, Hospital de Clínicas de Porto Alegre, Universidade Federal of Rio Grande do Sul, Porto Alegre, Brazil (A.B.S.S.); Division of Cardiovascular Medicine, Sarver Heart Center, University of Arizona College of Medicine, Tucson (N.K.S.); Cardiology Division, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S.); Cardiovascular Division, VA Medical Center, Minneapolis, MN (I.S.A.); Cardiology Division, University of Utah School of Medicine, Salt Lake City (J.F.); RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina, Charleston (M.R.Z.); and Cardiology Division, University of Michigan School of Medicine, Ann Arbor (B.P.).

2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.
Circulation 2016 Mar 21;133(11):1135-47. Epub 2015 Oct 21.
Writing committee members are required to recuse themselves from voting on sections to which their specific relationships with industry may apply; see Appendixes 1 and 2 for detailed information. ACC/AHA Representative. SCAI Representative. ACC/AHA Task Force on Clinical Practice Guidelines Liaison. Dr. Deborah D. Ascheim accepted a position at Capricor Therapeutics in August 2015, after the writing effort was completed. In accordance with ACC/AHA policy, she recused herself from the final voting process. ACP Representative. ACEP Representative. Former Task Force member; current member during the writing effort.


Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations.
J Heart Lung Transplant 2016 Mar 23;35(3):335-341. Epub 2015 Oct 23.
Intermountain Heart Institute and Intermountain Healthcare, Murray, Utah; University of Utah School of Medicine, Salt Lake City, Utah; Utah Transplantation Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah.

Impact of Spironolactone on Longitudinal Changes in Health-Related Quality of Life in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial.
Circ Heart Fail 2016 Mar;9(3):e001937
From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (E.F.L., B.C., S.D.S., A.S.D., M.A.P.); New England Research Institutes, Watertown, MA (H.-Y.K., S.F.A., C.T.K., S.A.M.); Mid America Heart Institute/UMKC, Kansas City, MO (J.S.); Division of Cardiology, New York Methodist Hospital, Brooklyn (J.F.H.); University of Utah, Division of Cardiology, Salt Lake City (J.C.F.); and University of Michigan School of Medicine, Ann Arbor (B.A.P.).

Impact of QRS duration on survival benefit with prophylactic implantable cardioverter-defibrillators: a meta-analysis of randomized controlled trials.
J Cardiovasc Med (Hagerstown) 2015 Dec;16(12):811-6
aAcibadem University Medical School, Department of Cardiology, Istanbul, Turkey bHarrington Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio cMayo Clinic, Rochester, Minnesota, USA.




Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery.
J Am Coll Cardiol 2014 Oct;64(15):1602-12
Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program: Divisions of Cardiovascular Medicine and Cardiothoracic Surgery, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah; University of Utah Molecular Medicine Program, Salt Lake City, Utah. Electronic address:

Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes.
Circulation 2014 Jun 5;129(23):2380-7. Epub 2014 May 5.
From the University Hospitals Case Medical Center, Harrington Heart and Vascular Institute, Cleveland, OH (A.B., J.C.F.); Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH (A.B.); Department of Biostatistics and Epidemiology (B.F., B.K.) and Penn Cardiovascular Institute (B.F., B.K., E.V., C.O., T.P.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Division of Cardiovascular Medicine, University of Arizona, Tucson (N.K.S.); and Division of Cardiovascular Medicine, University of Utah, Salt Lake City (J.C.F.).

Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure.
J Am Coll Cardiol 2013 Sep 13;62(13):1165-72. Epub 2013 Jun 13.
Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. Electronic address:










Effect of antihypertensive therapy on incident stroke in cohorts with prehypertensive blood pressure levels: a meta-analysis of randomized controlled trials.
Stroke 2012 Feb 8;43(2):432-40. Epub 2011 Dec 8.
Heart Failure & Transplantation, Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave LKS 5038, Cleveland, OH 44106, USA.




Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.
Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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