James C Fang

James C Fang

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James C Fang

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100Publications

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Perturbations in serum chloride homeostasis in heart failure with preserved ejection fraction: insights from TOPCAT.

Eur J Heart Fail 2018 Oct 12;20(10):1436-1443. Epub 2018 Jun 12.

Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.

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October 2018

The frailty syndrome and outcomes in the TOPCAT trial.

Eur J Heart Fail 2018 Sep 18. Epub 2018 Sep 18.

Cardiovascular Division, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

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September 2018

Cardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study.

Circ Cardiovasc Imaging 2018 Apr;11(4):e007117

Utah Transplantation Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program: University of Utah Health Sciences Center, Intermountain Medical Center, and Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah (M.J.B., A.K., O.W.-P., I.T., J.S., W.X., J.W.-P., A.C., J.N.-N., J.C.F., A.G.K., B.D.H., C.H.S., S.G.D.); Heart Failure and Transplant Unit, Onassis Cardiac Surgery Center, Athens, Greece (M.J.B., S.N.A.); and Department of Cardiology, Leiden University Medical Center, Netherlands (J.J.B.); 3rd Department of Cardiology, National and Kapodistrian University of Athens , Athens, Greece (S.G.D.).

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April 2018

When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation.

Circ Heart Fail 2018 Apr;11(4):e005116

Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Aurora (L.A.A.). Division of Cardiovascular Medicine, Department of Medicine, University of California San Diego (E.D.A.). l'Institut del Cor, Hospital Universitari Germans Trias i Pujol, Badalona, Spain (A.B.-G.). Temple Heart and Vascular Institute, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (M.A.B.-B.). Division of Cardiology, Department of Medicine, University of Pennsylvania, Philadelphia (J.A.C.). Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (B.L.C., C.Y.H.). Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City (J.C.F.). Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark (F.G.). The Cardiovascular Center, Tufts Medical Center, Boston, MA (N.K.K.). Sarver Heart Center, University of Arizona, Tucson (J.L.C., S.E.K., N.K.S.). Section of Advanced Heart Failure and Mechanical Circulatory Support, UMass Memorial Medical Center, Worcester, MA (R.D.K.). Section of Advanced Heart Failure and Transplant Cardiology, Henry Ford Hospital, Detroit, MI (D.E.L.). Department of Medicine, Minneapolis VA Health Care System and University of Minnesota, Minneapolis (O.V.).

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April 2018

Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma.

Circ Heart Fail 2018 Mar;11(3):e004408

From the Division of Cardiovascular Medicine (A.B.C., J.C.F.) and Division of Oncology (N.A.), Department of Medicine, University of Utah, Salt Lake City; Department of Biostatistics, Epidemiology and Informatics (R.A.H., B.K.), Division of Cardiology (J.A.C., D.H., A.M.S., T.P., V.E., B.K.), Division of Hematology and Oncology (S.K., N.B.H., V.N.), and Division of Nephrology (R.T.), Department of Medicine, and Abramson Cancer Center (S.K., N.B.H., V.N., B.K.), University of Pennsylvania, Philadelphia; Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY (I.P.); Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison (S.E.); Division of Cardiovascular Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH (C.E.); Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (M.G.); and Division of Cardiology, Department of Medicine, Washington University in St Louis, MO (D.L.).

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March 2018

Racial Differences in Characteristics and Outcomes of Patients With Heart Failure and Preserved Ejection Fraction in the Treatment of Preserved Cardiac Function Heart Failure Trial.

Circ Heart Fail 2018 Mar;11(3):e004457

From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (E.F.L., B.C., A.M.S., J.L., A.S.D., S.D.S., M.A.P.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S.); Veterans Affairs Medical Center Minneapolis, Minnesota (I.A.); University of Minnesota Medical School, Minneapolis (I.A.); Veterans Affairs Medical Center at San Diego, CA (I.A.); Montreal Heart Institute, Quebec, Canada (J.L.R., E.O.); Department of Medicine, Sarver Heart Center, University of Arizona, Tucson (N.K.S.); Division of Cardiology, University of Utah, Salt Lake City (J.C.F.); Department of Medicine, Howard University College of Medicine, Washington, DC (T.M.R.); Division of Cardiology, New York Methodist Hospital, Brooklyn (J.F.H.); Division of Cardiology, University of Illinois at Chicago (T.D.S.); National Heart, Lung, and Blood Institute, Bethesda, MD (R.B.); and University of Michigan School of Medicine, Ann Arbor (B.P.).

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March 2018

Clinical and histopathological effects of heart failure drug therapy in advanced heart failure patients on chronic mechanical circulatory support.

Eur J Heart Fail 2018 01 1;20(1):164-174. Epub 2017 Nov 1.

Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program, Divisions of Cardiovascular Medicine and Cardiovascular Surgery, University of Utah Health Sciences Center, Salt Lake VA Medical Center, Intermountain Medical Center, Salt Lake City, UT, USA.

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January 2018

Sudden death mechanisms in nonischemic cardiomyopathies: Insights gleaned from clinical implantable cardioverter-defibrillator trials.

Heart Rhythm 2017 12 23;14(12):1839-1848. Epub 2017 Sep 23.

Department of Cardiovascular Diseases, Mayo Clinic College of Medicine and Sciences, Rochester, Minnesota. Electronic address:

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December 2017

Long-Term Outcomes of Acute Heart Failure: Where Are We Now?

J Am Coll Cardiol 2017 Nov 12;70(20):2487-2489. Epub 2017 Nov 12.

Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.

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November 2017

Exertional Angina Due To Fused Aortic Bioprosthesis During Left Ventricular Assist Device Support: Two Cases and Review of the Literature.

ASAIO J 2017 Jan/Feb;63(1):e6-e9

From the Divisions of *Cardiovascular Medicine and †Cardiothoracic Surgery, Cardiac Mechanical Support Program; University of Utah, Salt Lake City, Utah.

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October 2017

Physical Activity and Prognosis in the TOPCAT Trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist).

Circulation 2017 Sep 21;136(11):982-992. Epub 2017 Jun 21.

From Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (S.M.H., B.C., A.M.S., E.F.L., M.A.P., S.D.S.); Department of Cardiology, VA Medical Center and Division of Cardiovascular Medicine, University of Minnesota, Minneapolis (I.A.); Cardiology Division, Northwestern University, Chicago, IL (S.J.S.); Division of Cardiology, University of Arizona, Tucson (N.K.S.); Division of Cardiovascular Medicine, University of Utah, Salt Lake City (J.D.F.); and Cardiovascular Medicine Division, University of Michigan School of Medicine, Ann Arbor (B.P.).

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September 2017

Goldilocks Dilemma of Dose Titration in Heart Failure With Reduced Ejection Fraction: Too Little, Too Much, or Just Right?

Circ Heart Fail 2017 Aug;10(8)

From the Division of Cardiology, University of Colorado School of Medicine, Aurora (L.A.A.); and Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City (J.C.F.).

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August 2017

The heart-kidney relationship in heart failure: it's not you, it's me.

Eur J Heart Fail 2017 05 15;19(5):624-626. Epub 2017 Mar 15.

University of Utah Health Sciences Center, Salt Lake City, UT, USA.

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May 2017

Association of recipient age and causes of heart transplant mortality: Implications for personalization of post-transplant management-An analysis of the International Society for Heart and Lung Transplantation Registry.

J Heart Lung Transplant 2017 Apr 20;36(4):407-417. Epub 2016 Aug 20.

Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, University of Utah Health Center and Veterans Affairs Medical CentePlease check the following authors groups Abdallah G. Kfoury, Stavros G. Drakos, Craig H. Selzman affilation citation is missing.-->r, Intermountain Medical Center, Salt Lake City, Utah. Electronic address:

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April 2017

Acute Coronary Syndrome Resulting From Systolic Compression of Left Main Coronary Artery Secondary to Aortic Subvalvular Aneurysm.

JACC Cardiovasc Interv 2017 Apr 15;10(7):e69-e70. Epub 2017 Mar 15.

Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, Utah. Electronic address:

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April 2017

Central Sleep Apnea in Heart Failure: Sleeping With the Wrong Enemy?

J Am Coll Cardiol 2017 Mar;69(12):1588-1591

University of Utah, Salt Lake City, Utah.

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March 2017

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.

Am J Cardiol 2016 Dec 15;118(12):1855-1860. Epub 2016 Sep 15.

Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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December 2016

An Age-Old Question: What Is Too Old for Coronary Artery Bypass Grafting in Heart Failure?

Circulation 2016 11;134(18):1325-1327

From Division of Cardiothoracic Surgery (S.H.M.) and Division of Cardiovascular Medicine (J.C.F.), University of Utah, School of Medicine, Salt Lake City, UT.

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November 2016

Back to the Future: Circulation Time Revisited.

J Card Fail 2016 11 9;22(11):928-929. Epub 2016 Sep 9.

University of Utah Health Sciences Center, Salt Lake City, Utah. Electronic address:

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November 2016

Cardiac Recovery During Long-Term Left Ventricular Assist Device Support.

J Am Coll Cardiol 2016 10;68(14):1540-53

Utah Cardiac Recovery Program, Salt Lake City, Utah; Veterans Affairs Medical Center, Salt Lake City, Utah; Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah. Electronic address:

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October 2016

Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical Unloading.

J Am Coll Cardiol 2016 10;68(16):1741-1752

Utah Transplantation Affiliated Hospitals Cardiac Transplant Program, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah; University of Utah Molecular Medicine Program, Salt Lake City, Utah. Electronic address:

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October 2016

Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning.

JACC Basic Transl Sci 2016 Oct 31;1(6):432-444. Epub 2016 Oct 31.

Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah.

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October 2016

Unexpected Etiology of Atypical Chest Pain.

Am J Med 2016 Sep 3;129(9):e185-6. Epub 2016 May 3.

Division of Cardiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City.

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September 2016

Taking NO for an Answer: Exploring the Therapeutic Potential of Nitrite in HFpEF.

Circ Res 2016 09;119(7):782-4

From the Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City.

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September 2016

Immunologic effects of continuous-flow left ventricular assist devices before and after heart transplant.

J Heart Lung Transplant 2016 08 6;35(8):1024-30. Epub 2016 May 6.

Division of Cardiovascular Disease, University of Utah Health Sciences Center, Salt Lake City, Utah; George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah; Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah.

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August 2016

Heart Failure With Preserved Ejection Fraction: A Kidney Disorder?

Authors:
James C Fang

Circulation 2016 Aug;134(6):435-7

From School of Medicine, University of Utah Health Sciences Center, Salt Lake City.

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August 2016

Management of Patients With Recovered Systolic Function.

Prog Cardiovasc Dis 2016 Jan-Feb;58(4):434-43. Epub 2016 Jan 12.

University of Utah, Salt Lake City, UT. Electronic address:

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July 2016

Advanced Therapies for Advanced Heart Failure: Time to Raise Awareness.

Heart Fail Clin 2016 Jul;12(3):ix-x

Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

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July 2016

Heart Failure With a Better Ejection Fraction: Why Should We Care?

Circ Heart Fail 2016 07;9(7)

From the OhioHealth Heart & Vascular Department, Riverside Methodist Hospital, Columbus (A.B.); and Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City (J.C.F.).

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July 2016

Dealing With Unintended Consequences: Continuous-Flow LVADs and Aortic Insufficiency.

JACC Cardiovasc Imaging 2016 06 9;9(6):652-4. Epub 2015 Dec 9.

Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.

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June 2016

2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial Infarction: An update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.

Catheter Cardiovasc Interv 2016 May;87(6):1001-19

Former Task Force member; current member during the writing effort.

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May 2016

Prognostic Value of Galectin-3 for Adverse Outcomes in Chronic Heart Failure.

J Card Fail 2016 Apr 10;22(4):256-62. Epub 2015 Nov 10.

Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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April 2016

Prognostic Relevance of Left Atrial Dysfunction in Heart Failure With Preserved Ejection Fraction.

Circ Heart Fail 2016 Apr;9(4):e002763

From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (A.B.S.S., G.Q.R., B.C., S.D.S., A.M.S.); Cardiology Division, Hospital de Clínicas de Porto Alegre, Universidade Federal of Rio Grande do Sul, Porto Alegre, Brazil (A.B.S.S.); Division of Cardiovascular Medicine, Sarver Heart Center, University of Arizona College of Medicine, Tucson (N.K.S.); Cardiology Division, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S.); Cardiovascular Division, VA Medical Center, Minneapolis, MN (I.S.A.); Cardiology Division, University of Utah School of Medicine, Salt Lake City (J.F.); RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina, Charleston (M.R.Z.); and Cardiology Division, University of Michigan School of Medicine, Ann Arbor (B.P.).

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April 2016

Gastrointestinal and Liver Issues in Heart Failure.

Circulation 2016 Apr;133(17):1696-703

From Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH (V.S.); and Division of Cardiovascular Medicine, University of Utah Health Science Center, Salt Lake City (J.C.F.).

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April 2016

2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.

Circulation 2016 Mar 21;133(11):1135-47. Epub 2015 Oct 21.

Writing committee members are required to recuse themselves from voting on sections to which their specific relationships with industry may apply; see Appendixes 1 and 2 for detailed information. ACC/AHA Representative. SCAI Representative. ACC/AHA Task Force on Clinical Practice Guidelines Liaison. Dr. Deborah D. Ascheim accepted a position at Capricor Therapeutics in August 2015, after the writing effort was completed. In accordance with ACC/AHA policy, she recused herself from the final voting process. ACP Representative. ACEP Representative. Former Task Force member; current member during the writing effort.

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March 2016

Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations.

J Heart Lung Transplant 2016 Mar 23;35(3):335-341. Epub 2015 Oct 23.

Intermountain Heart Institute and Intermountain Healthcare, Murray, Utah; University of Utah School of Medicine, Salt Lake City, Utah; Utah Transplantation Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah.

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March 2016

Impact of Spironolactone on Longitudinal Changes in Health-Related Quality of Life in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial.

Circ Heart Fail 2016 Mar;9(3):e001937

From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (E.F.L., B.C., S.D.S., A.S.D., M.A.P.); New England Research Institutes, Watertown, MA (H.-Y.K., S.F.A., C.T.K., S.A.M.); Mid America Heart Institute/UMKC, Kansas City, MO (J.S.); Division of Cardiology, New York Methodist Hospital, Brooklyn (J.F.H.); University of Utah, Division of Cardiology, Salt Lake City (J.C.F.); and University of Michigan School of Medicine, Ann Arbor (B.A.P.).

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March 2016

Reply: Bridging Anticoagulation.

J Am Coll Cardiol 2016 Feb;67(7):891

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February 2016

Cardiovascular Risk Assessment and Management in Prerenal Transplantation Candidates.

Am J Cardiol 2016 Jan 17;117(1):146-50. Epub 2015 Oct 17.

Division of Cardiovascular Medicine, University of Utah Hospitals and Clinics, Salt Lake City, Utah.

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January 2016

Impact of QRS duration on survival benefit with prophylactic implantable cardioverter-defibrillators: a meta-analysis of randomized controlled trials.

J Cardiovasc Med (Hagerstown) 2015 Dec;16(12):811-6

aAcibadem University Medical School, Department of Cardiology, Istanbul, Turkey bHarrington Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio cMayo Clinic, Rochester, Minnesota, USA.

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December 2015

Bridging Anticoagulation: Primum Non Nocere.

J Am Coll Cardiol 2015 Sep;66(12):1392-403

Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.

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September 2015

Team-based Care for Advanced Heart Failure.

Heart Fail Clin 2015 Jul;11(3):467-77

Department of Medicine, Division of Cardiology, University of Utah Health Sciences Center, 30 North Medical Drive, 4A100 SOM, Salt Lake City, UT 84132, USA. Electronic address:

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July 2015

Emergent cesarean section in the catheterization laboratory for spontaneous coronary artery dissection.

Am J Cardiol 2015 Jun 24;115(12):1777-8. Epub 2015 Mar 24.

Division of Cardiovascular Medicine, University of Utah Health Care, Salt Lake City, Utah.

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June 2015

Pulmonary hypertension in heart failure: measurable, but how meaningful?

J Heart Lung Transplant 2015 Mar 23;34(3):310-1. Epub 2014 Aug 23.

Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah.

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March 2015

Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery.

J Am Coll Cardiol 2014 Oct;64(15):1602-12

Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program: Divisions of Cardiovascular Medicine and Cardiothoracic Surgery, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah; University of Utah Molecular Medicine Program, Salt Lake City, Utah. Electronic address:

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October 2014

Biomarker predictors of cardiac hospitalization in chronic heart failure: a recurrent event analysis.

J Card Fail 2014 Aug 11;20(8):569-76. Epub 2014 Jun 11.

Penn Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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August 2014

Current therapeutic approach in heart failure with preserved ejection fraction.

Heart Fail Clin 2014 Jul;10(3):525-38

Division of Cardiovascular Medicine, Department of Medicine, University of Utah Health Science Center, 50 N Medical Dr, Salt Lake City, UT 84132, USA; Cardiology Section, Veterans Affairs Salt Lake City Health Care System, 500 Foothill Dr, Salt Lake City, UT 84148, USA. Electronic address:

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July 2014

Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes.

Circulation 2014 Jun 5;129(23):2380-7. Epub 2014 May 5.

From the University Hospitals Case Medical Center, Harrington Heart and Vascular Institute, Cleveland, OH (A.B., J.C.F.); Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH (A.B.); Department of Biostatistics and Epidemiology (B.F., B.K.) and Penn Cardiovascular Institute (B.F., B.K., E.V., C.O., T.P.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Division of Cardiovascular Medicine, University of Arizona, Tucson (N.K.S.); and Division of Cardiovascular Medicine, University of Utah, Salt Lake City (J.C.F.).

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June 2014

Pharmacologic therapies for acute cardiogenic shock.

Curr Opin Cardiol 2014 May;29(3):250-7

aDivision of Cardiovascular Medicine, Department of Medicine, University of Utah School of Medicine bCardiology Section, Veterans Affairs Salt Lake City Healthcare System cDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.

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May 2014

Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure.

J Am Heart Assoc 2014 Jan 13;3(1):e000550. Epub 2014 Jan 13.

Penn Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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January 2014

Moving beyond "bridges".

JACC Heart Fail 2013 Oct 7;1(5):379-81. Epub 2013 Oct 7.

Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.

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October 2013

Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure.

J Am Coll Cardiol 2013 Sep 13;62(13):1165-72. Epub 2013 Jun 13.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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September 2013

The world post-STICH: is this a "Game Changer?" A non-invasive cardiologist's perspective-revascularization is the treatment of choice only in patients who fail medical therapy.

Prog Cardiovasc Dis 2013 Mar-Apr;55(5):466-9

Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, USA.

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May 2013

CRT should be reserved for a QRS duration ≥150 ms: pro.

Circ Arrhythm Electrophysiol 2013 Apr;6(2):436-42

Department of Cardiology, Acibadem University School of Medicine, Acibadem Maslak Hospital, Istanbul, Turkey.

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April 2013

Reversal of severe biventricular dysfunction from cardiac hemochromatosis with iron removal.

Circ Heart Fail 2013 Jan;6(1):e14-5

Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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January 2013

Heart failure therapy: what should clinicians believe?

Authors:
James C Fang

JAMA 2012 Nov;308(20):2144-6

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November 2012

Multiple biomarkers for risk prediction in chronic heart failure.

Circ Heart Fail 2012 Mar 23;5(2):183-90. Epub 2012 Feb 23.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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March 2012

Effect of antihypertensive therapy on incident stroke in cohorts with prehypertensive blood pressure levels: a meta-analysis of randomized controlled trials.

Stroke 2012 Feb 8;43(2):432-40. Epub 2011 Dec 8.

Heart Failure & Transplantation, Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave LKS 5038, Cleveland, OH 44106, USA.

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February 2012

Effect of QRS morphology on clinical event reduction with cardiac resynchronization therapy: meta-analysis of randomized controlled trials.

Am Heart J 2012 Feb;163(2):260-7.e3

Harrington-McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, USA.

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February 2012

Impact of QRS duration on clinical event reduction with cardiac resynchronization therapy: meta-analysis of randomized controlled trials.

Arch Intern Med 2011 Sep 13;171(16):1454-62. Epub 2011 Jun 13.

Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

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September 2011

Meta-analysis of randomized controlled trials on effect of angiotensin-converting enzyme inhibitors on cancer risk.

Am J Cardiol 2011 Jul 19;108(2):294-301. Epub 2011 May 19.

Harrington-McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

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July 2011

The vascular marker soluble fms-like tyrosine kinase 1 is associated with disease severity and adverse outcomes in chronic heart failure.

J Am Coll Cardiol 2011 Jul;58(4):386-94

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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July 2011

Treatment of heart failure with preserved ejection fraction: have we been pursuing the wrong paradigm?

Mayo Clin Proc 2011 Jun 16;86(6):531-9. Epub 2011 May 16.

Division of Cardiovascular Medicine, University Hospitals of Cleveland, Case Medical Center, Cleveland, OH, USA.

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June 2011

Underestimating medical therapy for coronary disease... again.

Authors:
James C Fang

N Engl J Med 2011 Apr 4;364(17):1671-3. Epub 2011 Apr 4.

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April 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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Treating heart failure on dialysis. Finally getting some evidence.

J Am Coll Cardiol 2010 Nov;56(21):1709-11

Harrington-McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.

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