James A Whitlock

James A Whitlock

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James A Whitlock

James A Whitlock

Publications by authors named "James A Whitlock"

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Bortezomib reinduction chemotherapy in high-risk ALL in first relapse: a report from the Children's Oncology Group.

Br J Haematol 2019 Jul 7;186(2):274-285. Epub 2019 Apr 7.

Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.15919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606340PMC
July 2019

Atypical juvenile histiocytosis with novel KIF5B-ALK gene fusion mimicking subglottic hemangioma.

Int J Pediatr Otorhinolaryngol 2019 Jul 13;126:109585. Epub 2019 Jul 13.

Department of Otolaryngology, Hospital for Sick Children, Toronto, ON, Canada; Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijporl.2019.07.010DOI Listing
July 2019

Treatment of Postanoxic Action Myoclonus With Intrathecal Baclofen: A Case Report.

PM R 2018 08 31;10(8):870-872. Epub 2018 Jan 31.

VA Medical Center, 178 Smyth Road, Manchester, NH 03104.

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http://dx.doi.org/10.1016/j.pmrj.2017.12.010DOI Listing
August 2018

Optimizing autologous nonmobilized mononuclear cell collections for cellular therapy in pediatric patients with high-risk leukemia.

Transfusion 2017 06 25;57(6):1536-1542. Epub 2017 Apr 25.

Division of Haematology/Oncology/Bone Marrow Transplantation, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1111/trf.14094
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http://dx.doi.org/10.1111/trf.14094DOI Listing
June 2017

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia.

J Clin Oncol 2016 12 31;34(36):4381-4389. Epub 2016 Oct 31.

Arend von Stackelberg, Charité Campus Virchow, Berlin; Gerhard Zugmaier, Amgen Research (Munich), Munich; Rupert Handgretinger, University of Tübingen, Tübingen; Peter Bader, Hospital for Children and Adolescents III, University of Frankfurt, Frankfurt; Paul Gerhardt Schlegel, University Children's Hospital Würzburg, Würzburg; Arndt Borkhardt, University of Düsseldorf Medical Faculty, Düsseldorf, Germany; Franco Locatelli, Ospedale Pediatrico Bambino Gesù, Rome, University of Pavia, Pavia; Carmelo Rizzari, San Gerardo Hospital, University of Milano-Bicocca, Monza; Chiara Messina, Clinica di Oncoematologia Pediatrica, Università degli Studi di Padova, Padova, Italy; Benoît Brethon, Hôpital Robert Debré, Service Hématologie-Immunologie Pédiatrique, Paris; Gérard Michel, Hôpital de la Timone, Marseille, France; Christian M. Zwaan, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, Netherlands; Tanya M. Trippett, Memorial Sloan Kettering Cancer Center, New York, NY; Maureen M. O'Brien, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Deepa Bhojwani, Children's Hospital of Los Angeles; Kuolung Hu and Min Zhu, Amgen, Thousand Oaks, CA; Susan R. Rheingold, Children's Hospital of Philadelphia, Philadelphia, PA; Todd Michael Cooper, Seattle Children's Hospital, Seattle, WA; Phillip Barnette, Primary Children's Medical Center, Salt Lake City, UT; Steven G. DuBois, Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA; Lia Gore, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; and James A. Whitlock, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2016.67.3301
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http://dx.doi.org/10.1200/JCO.2016.67.3301DOI Listing
December 2016

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

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http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

Updates on histiocytic disorders.

Pediatr Blood Cancer 2014 Jul 9;61(7):1329-35. Epub 2014 Mar 9.

Children's Cancer Center, Staten Island University Hospital, Staten Island, New York.

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http://dx.doi.org/10.1002/pbc.25017DOI Listing
July 2014

Recent advances in acute lymphoblastic leukemia in children and adolescents: an expert panel discussion.

Curr Opin Oncol 2013 Dec;25 Suppl 3:S1-13; quiz S14-6

aGolisano Children's Hospital, University of Rochester Medical Center, Rochester, New York bDepartment of Hematology/Oncology, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California, USA cUniversity of Toronto dDivision of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/CCO.0000000000000017DOI Listing
December 2013

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia.

Pediatr Blood Cancer 2013 Jun 19;60(6):957-63. Epub 2012 Dec 19.

University of Colorado School of Medicine, The University of Colorado Cancer Center and Children's Hospital Colorado, Aurora, Colorado, USA.

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http://dx.doi.org/10.1002/pbc.24420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045498PMC
June 2013

Childhood T-all: it's time to move on.

Blood 2011 Jul;118(4):828-9

Hospital for Sick Children, Dana-farber Cancer Institute, USA.

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http://dx.doi.org/10.1182/blood-2011-05-348375DOI Listing
July 2011

Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia.

Pediatr Blood Cancer 2011 Mar;56(3):372-8

Department of Pediatrics, Vanderbilt University School of Medicine and Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1002/pbc.22782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713225PMC
March 2011

Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement.

Pediatr Blood Cancer 2011 Mar 28;56(3):353-60. Epub 2010 Nov 28.

Hughes' Children's Cancer Research Centre, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/pbc.22760DOI Listing
March 2011

Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.

Pediatr Blood Cancer 2009 Dec;53(7):1327-8

Division of Pediatric Hematology/Oncology, Vanderbilt University, Nashville, Tennessee 37232-6310, USA.

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http://dx.doi.org/10.1002/pbc.22182DOI Listing
December 2009

Targeting the Bcl-2 family of proteins in Hodgkin lymphoma: in vitro cytotoxicity, target modulation and drug combination studies of the Bcl-2 homology 3 mimetic ABT-737.

Leuk Lymphoma 2009 Jul;50(7):1174-82

Hughes' Children's Cancer Research Centre, Division of Pediatric Oncology, Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1080/10428190902943069DOI Listing
July 2009

Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia.

J Pediatr Psychol 2009 Apr 30;34(3):317-27. Epub 2008 Jul 30.

Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, P.O. Box 800223, Charlottesville, VA 22908-0223, USA.

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http://dx.doi.org/10.1093/jpepsy/jsn080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722127PMC
April 2009

Malignancy in children with trisomy 21.

Oncologist 2009 Feb 28;14(2):164-73. Epub 2009 Jan 28.

Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1634/theoncologist.2008-0217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761094PMC
February 2009

Treatment of juvenile xanthogranuloma.

Pediatr Blood Cancer 2008 Jul;51(1):130-3

Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://doi.wiley.com/10.1002/pbc.21523
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http://dx.doi.org/10.1002/pbc.21523DOI Listing
July 2008

A meta-analysis of the neurocognitive sequelae of treatment for childhood acute lymphocytic leukemia.

Pediatr Blood Cancer 2007 Jul;49(1):65-73

Vanderbilt University, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1002/pbc.20860DOI Listing
July 2007

Safety and efficacy of a continuous infusion, patient-controlled antiemetic pump for children receiving emetogenic chemotherapy.

Pediatr Blood Cancer 2007 Mar;48(3):330-2

Pediatric Hematology/Oncology, Vanderbilt University, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1002/pbc.20711DOI Listing
March 2007

Down syndrome and acute lymphoblastic leukaemia.

Authors:
James A Whitlock

Br J Haematol 2006 Dec 10;135(5):595-602. Epub 2006 Oct 10.

Division of Pediatric Hematology/Oncology, Vanderbilt Children's Hospital and Vanderbilt-Ingram Cancer Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2006.06337.xDOI Listing
December 2006

Utility of FDG-PET/CT in follow-up of children treated for Hodgkin and non-Hodgkin lymphoma.

J Pediatr Hematol Oncol 2006 May;28(5):300-6

Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6310, USA.

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http://dx.doi.org/10.1097/01.mph.0000212912.37512.b1DOI Listing
May 2006

Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study.

Blood 2005 Dec 18;106(13):4043-9. Epub 2005 Aug 18.

Department of Pediatric Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1182/blood-2003-10-3446DOI Listing
December 2005

Phase I clinical and pharmacokinetic study of flavopiridol in children with refractory solid tumors: a Children's Oncology Group Study.

J Clin Oncol 2005 Dec;23(36):9179-86

Vanderbilt Children's Hospital, Pediatric Hematology/Oncology, Nashville TN 37232-6310, USA.

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http://dx.doi.org/10.1200/JCO.2004.01.0660DOI Listing
December 2005

Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952.

Pediatr Blood Cancer 2005 Jan;44(1):21-8

Pediatric Hematology/Oncology/BMT, University of Colorado Health Sciences Center, Denver, Colorado, USA.

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http://dx.doi.org/10.1002/pbc.20193DOI Listing
January 2005

Improving pediatric chemotherapy safety through voluntary incident reporting: lessons from the field.

J Pediatr Oncol Nurs 2004 Jul-Aug;21(4):200-6

Center for Improving Patient Safety, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1177/1043454204265907DOI Listing
November 2004

Circumstances surrounding the deaths of hospitalized children: opportunities for pediatric palliative care.

Pediatrics 2004 Sep;114(3):e361-6

Vanderbilt Children's Hospital, Vanderbilt University School of Medicine, TN, USA.

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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2003-0654-FDOI Listing
September 2004

A novel t(2;20)(q35;p12) in embryonal rhabdomyosarcoma.

Cancer Genet Cytogenet 2004 May;151(1):73-7

Division of Pediatric Hematology/Oncology, Department of Pediatrics, Vanderbilt University Medical Center, 2220 Pierce Avenue, Nashville, TN 37232-6310, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2003.08.023DOI Listing
May 2004

Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein.

Clin Infect Dis 2003 Nov 17;37(10):e136-41. Epub 2003 Oct 17.

Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2581, USA.

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http://dx.doi.org/10.1086/379126DOI Listing
November 2003

A chemotherapy incident reporting and improvement system.

Jt Comm J Qual Saf 2003 Apr;29(4):171-80

Vanderbilt University Medical Center, Center for Clinical Improvement, Nashville, Tennessee, USA.

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April 2003