James A Traherne

James A Traherne

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James A Traherne

James A Traherne

Publications by authors named "James A Traherne"

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36Publications

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High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

J Immunol 2018 11 24;201(9):2593-2601. Epub 2018 Sep 24.

Department of Obstetrics and Gynaecology, University of Cambridge School of Clinical Medicine, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge CB2 0SW, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1800860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258046PMC
November 2018

Novel KIR genotypes and gene copy number variations in northeastern Thais.

Immunology 2018 03 23;153(3):380-386. Epub 2017 Oct 23.

The Centre for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.1111/imm.12847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795178PMC
March 2018

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology.

Immunology 2017 03 14;150(3):248-264. Epub 2016 Dec 14.

Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/imm.12684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290243PMC
March 2017

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

Cell Rep 2016 05 21;15(5):1088-1099. Epub 2016 Apr 21.

Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14186 Stockholm, Sweden; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, 75015 Paris, France; University Paris Descartes, Imagine Institute, 75270 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858565PMC
May 2016

Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population.

PLoS One 2014 18;9(12):e114486. Epub 2014 Dec 18.

Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G Jebsen Inflammation Research Centre, Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; Section for Gastroenterology, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114486PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270690PMC
December 2015

Imputation of KIR Types from SNP Variation Data.

Am J Hum Genet 2015 Oct;97(4):593-607

Statistical Genetics, Murdoch Childrens Research Institute, Parkville, VIC 3052, Australia; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596914PMC
October 2015

Surveillance of cell and tissue perturbation by receptors in the LRC.

Immunol Rev 2015 Sep;267(1):117-36

Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/imr.12314DOI Listing
September 2015

KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.

Immunogenetics 2014 Nov 21;66(11):597-611. Epub 2014 Aug 21.

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s00251-014-0794-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198482PMC
November 2014

Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR.

Genome Med 2014 5;6(3):20. Epub 2014 Mar 5.

Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge CB2 0XY, UK ; Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm5
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http://dx.doi.org/10.1186/gm537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062048PMC
August 2014

TAPBPR isoforms exhibit altered association with MHC class I.

Immunology 2014 Jun;142(2):289-99

Department of Pathology, Cambridge Institute of Medical Research, University of Cambridge, Wellcome Trust, Cambridge, UK.

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http://dx.doi.org/10.1111/imm.12253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008236PMC
June 2014

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

BMC Genomics 2014 Apr 11;15:274. Epub 2014 Apr 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, CB2 0XY, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2164-15-274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029094PMC
April 2014

Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors.

Immunogenetics 2014 Feb 21;66(2):73-83. Epub 2013 Nov 21.

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.

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http://link.springer.com/10.1007/s00251-013-0742-5
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http://dx.doi.org/10.1007/s00251-013-0742-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894450PMC
February 2014

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors.

Genome Res 2012 Oct 4;22(10):1845-54. Epub 2012 Sep 4.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1101/gr.137976.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460180PMC
October 2012

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity.

Curr Opin Immunol 2010 Dec 1;22(6):715-22. Epub 2010 Nov 1.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Box 139 Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1016/j.coi.2010.10.003DOI Listing
December 2010

Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.

Hum Mol Genet 2010 Mar 3;19(5):737-51. Epub 2009 Dec 3.

Division of Immunology, Department of Pathology, University of Cambridge Cambridge CB2 1QP, UK.

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http://dx.doi.org/10.1093/hmg/ddp538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816608PMC
March 2010

ULBP6/RAET1L is an additional human NKG2D ligand.

Eur J Immunol 2009 Nov;39(11):3207-16

Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200939502DOI Listing
November 2009

SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.

Eur J Immunol 2008 Aug;38(8):2303-15

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200738078DOI Listing
August 2008

Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport.

J Neurochem 2007 Sep 15;102(6):1853-1862. Epub 2007 Jun 15.

Department of Pathology, Cambridge Institute of Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04687.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156149PMC
September 2007

Regulation of NKG2D ligand gene expression.

Hum Immunol 2006 Mar 17;67(3):159-69. Epub 2006 Apr 17.

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrookes Hospital, Cambridge, UK.

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http://dx.doi.org/10.1016/j.humimm.2006.02.015DOI Listing
March 2006

Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.

Hum Mol Genet 2006 Jan 1;15(1):155-61. Epub 2005 Dec 1.

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/ddi436DOI Listing
January 2006

LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta.

Hum Mol Genet 2003 Oct 27;12(20):2577-85. Epub 2003 Aug 27.

Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK.

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http://dx.doi.org/10.1093/hmg/ddg290DOI Listing
October 2003