Publications by authors named "James A Thomson"

100Publications

Maternal High-Fiber Diet Protects Offspring against Type 2 Diabetes.

Nutrients 2020 Dec 30;13(1). Epub 2020 Dec 30.

Regenerative Biology Laboratory, Morgridge Institute for Research, Madison, WI 53715, USA.

View Article and Find Full Text PDF
December 2020

Biologically Functionalized Expanded Polytetrafluoroethylene Blood Vessel Grafts.

Biomacromolecules 2020 09 21;21(9):3807-3816. Epub 2020 Aug 21.

Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

View Article and Find Full Text PDF
September 2020

Expanded Poly(tetrafluoroethylene) Blood Vessel Grafts with Embedded Reactive Oxygen Species (ROS)-Responsive Antithrombogenic Drug for Elimination of Thrombosis.

ACS Appl Mater Interfaces 2020 Jul 18;12(26):29844-29853. Epub 2020 Jun 18.

Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

View Article and Find Full Text PDF
July 2020

TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes.

Nucleic Acids Res 2020 05;48(9):e51

Regenerative Biology Laboratory, Morgridge Institute for Research, Madison, WI 53707, USA.

View Article and Find Full Text PDF
May 2020

An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells.

Cell Rep 2019 08;28(9):2247-2255.e5

Morgridge Institute for Research, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Molecular, Cellular, & Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93117, USA. Electronic address:

View Article and Find Full Text PDF
August 2019

3-D culture and endothelial cells improve maturity of human pluripotent stem cell-derived hepatocytes.

Acta Biomater 2019 09 27;95:371-381. Epub 2019 Jul 27.

Department of Biomedical Engineering, University of Wisconsin-Madison, WI, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, WI, USA. Electronic address:

View Article and Find Full Text PDF
September 2019

Inferring Regulatory Programs Governing Region Specificity of Neuroepithelial Stem Cells during Early Hindbrain and Spinal Cord Development.

Cell Syst 2019 08 10;9(2):167-186.e12. Epub 2019 Jul 10.

Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53792, USA. Electronic address:

View Article and Find Full Text PDF
August 2019

Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.

Lab Invest 2019 10 17;99(10):1547-1560. Epub 2019 May 17.

Center for Stem Cell Biology and Engineering, University of California at Santa Barbara, Santa Barbara, CA, USA.

View Article and Find Full Text PDF
October 2019

A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia.

Stem Cell Reports 2019 06 9;12(6):1269-1281. Epub 2019 May 9.

Regenerative Biology, Morgridge Institute for Research, 330 North Orchard Street, Madison, WI 53715, USA; Department of Cell & Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Molecular, Cellular, & Developmental Biology, University of California, Santa Barbara, CA 93117, USA. Electronic address:

View Article and Find Full Text PDF
June 2019

Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment.

Proc Natl Acad Sci U S A 2019 03 13;116(10):4346-4351. Epub 2019 Feb 13.

Lillehei Heart Institute, Department of Medicine, University of Minnesota, Minneapolis, MN 55455;

View Article and Find Full Text PDF
March 2019

Fabrication and modification of wavy multicomponent vascular grafts with biomimetic mechanical properties, antithrombogenicity, and enhanced endothelial cell affinity.

J Biomed Mater Res B Appl Biomater 2019 10 28;107(7):2397-2408. Epub 2019 Jan 28.

Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, Wisconsin, 53715, USA.

View Article and Find Full Text PDF
October 2019

Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds.

Dev Biol 2019 03 16;447(2):157-169. Epub 2019 Jan 16.

Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

View Article and Find Full Text PDF
March 2019

Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.

Int J Mol Sci 2018 Dec 19;19(12). Epub 2018 Dec 19.

Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA.

View Article and Find Full Text PDF
December 2018

Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells.

Stem Cell Reports 2018 12 29;11(6):1347-1356. Epub 2018 Nov 29.

Centre of Reproduction, Development & Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau, China; Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Taipa, Macau, China. Electronic address:

View Article and Find Full Text PDF
December 2018

A folic acid-enriched diet attenuates prostate involution in response to androgen deprivation.

Prostate 2019 02 8;79(2):183-194. Epub 2018 Oct 8.

Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.

View Article and Find Full Text PDF
February 2019

In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells.

Proc Natl Acad Sci U S A 2018 08 30;115(33):8394-8399. Epub 2018 Jul 30.

Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706;

View Article and Find Full Text PDF
August 2018

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition.

Stem Cell Reports 2018 07 31;11(1):197-211. Epub 2018 May 31.

Wisconsin National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53707-7365, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

View Article and Find Full Text PDF
July 2018

Activation of the Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential.

Cell Rep 2018 05;23(8):2467-2481

National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53707-7365, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

View Article and Find Full Text PDF
May 2018

Simultaneous reprogramming and gene editing of human fibroblasts.

Nat Protoc 2018 05 5;13(5):875-898. Epub 2018 Apr 5.

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.

View Article and Find Full Text PDF
May 2018

A Humanized Mouse Model Generated Using Surplus Neonatal Tissue.

Stem Cell Reports 2018 04 22;10(4):1175-1183. Epub 2018 Mar 22.

Division of Transplantation/Department of Surgery, University of Wisconsin, Madison, WI 53792, USA. Electronic address:

View Article and Find Full Text PDF
April 2018

Development of biomimetic thermoplastic polyurethane/fibroin small-diameter vascular grafts via a novel electrospinning approach.

J Biomed Mater Res A 2018 04 5;106(4):985-996. Epub 2017 Dec 5.

Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706.

View Article and Find Full Text PDF
April 2018

Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.

Stem Cells Dev 2017 09 24;26(17):1225-1235. Epub 2017 Jul 24.

2 Wisconsin National Primate Research Center, University of Wisconsin-Madison , Madison, Wisconsin.

View Article and Find Full Text PDF
September 2017

Specification and Diversification of Pericytes and Smooth Muscle Cells from Mesenchymoangioblasts.

Cell Rep 2017 05;19(9):1902-1916

Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53707, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53792, USA. Electronic address:

View Article and Find Full Text PDF
May 2017

SCnorm: robust normalization of single-cell RNA-seq data.

Nat Methods 2017 Jun 17;14(6):584-586. Epub 2017 Apr 17.

Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, USA.

View Article and Find Full Text PDF
June 2017

A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture.

Stem Cell Reports 2017 04 23;8(4):907-918. Epub 2017 Mar 23.

Department of Biomedical Engineering, University of Wisconsin-Madison, Wisconsin Institute for Medical Research, Room 5405, Madison, WI 53706, USA; Materials Science Program, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address:

View Article and Find Full Text PDF
April 2017

Species-specific developmental timing is maintained by pluripotent stem cells ex utero.

Dev Biol 2017 03 6;423(2):101-110. Epub 2017 Feb 6.

Morgridge Institute for Research, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA. Electronic address:

View Article and Find Full Text PDF
March 2017

Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2.

Nat Commun 2016 10 7;7:13101. Epub 2016 Oct 7.

Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota 55455, USA.

View Article and Find Full Text PDF
October 2016

Analysis of embryonic development in the unsequenced axolotl: Waves of transcriptomic upheaval and stability.

Dev Biol 2017 06 28;426(2):143-154. Epub 2016 Jul 28.

Regenerative Biology, Morgridge Institute for Research, Madison, WI, United States. Electronic address:

View Article and Find Full Text PDF
June 2017

Quality control of single-cell RNA-seq by SinQC.

Bioinformatics 2016 08 10;32(16):2514-6. Epub 2016 Apr 10.

Regenerative Biology Laboratory, Morgridge Institute for Research, Madison, WI 53707, USA.

View Article and Find Full Text PDF
August 2016

Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels.

Acta Biomater 2016 Apr 2;35:32-41. Epub 2016 Mar 2.

Department of Biomedical Engineering, University of Wisconsin-Madison, WI, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, WI, USA. Electronic address:

View Article and Find Full Text PDF
April 2016

Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors.

Cell Stem Cell 2016 Mar 11;18(3):354-67. Epub 2016 Feb 11.

Department of Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA; Molecular and Cellular Pharmacology Program, University of Wisconsin-Madison, Madison, WI 53705, USA; Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address:

View Article and Find Full Text PDF
March 2016

GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells.

Stem Cell Reports 2016 Feb 21;6(2):243-56. Epub 2016 Jan 21.

National Primate Research Center, University of Wisconsin, 1220 Capitol Court, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53707, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin, 1685 Highland Avenue, Madison WI 53705, USA. Electronic address:

View Article and Find Full Text PDF
February 2016

Development of Bipotent Cardiac/Skeletal Myogenic Progenitors from MESP1+ Mesoderm.

Stem Cell Reports 2016 Jan;6(1):26-34

Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Lillehei Heart Institute, University of Minnesota, Cancer and Cardiovascular Research Building 4-127, 2231 6th Street Southeast, Minneapolis, MN 55455, USA. Electronic address:

View Article and Find Full Text PDF
January 2016

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts.

Stem Cell Reports 2015 Dec 12;5(6):1109-1118. Epub 2015 Nov 12.

Morgridge Institute for Research, 330 North Orchard Street, Madison, WI 53715, USA; Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53707-7365, USA; Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106, USA.

View Article and Find Full Text PDF
December 2015

Development of a Model Protein Interaction Pair as a Benchmarking Tool for the Quantitative Analysis of 2-Site Protein-Protein Interactions.

J Biomol Tech 2015 Dec 29;26(4):125-41. Epub 2015 Oct 29.

1 Bristol-Myers Squibb, Princeton, New Jersey 08540, USA; 2 Tokyo Institute of Technology, Yokohama 226-8503, Japan; 3 Google[x], Google Life Sciences, Mountain View, California 94043, USA; 4 SystaMedic, Incorporated, Groton, Connecticut 06340, USA; 5 Biosensor Tools LLC, Salt Lake City, Utah 84103, USA; 6 National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA; 7 Polaris Pharmaceuticals, Incorporated, San Diego, California 92121, USA; and 8 Institute for Bioscience and Biotechnology Research, Fischell Department of Bioengineering, University of Maryland, Rockville, Maryland 20850, USA.

View Article and Find Full Text PDF
December 2015

Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation.

PLoS One 2015 25;10(9):e0139076. Epub 2015 Sep 25.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, United States of America; Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, Wisconsin, 53706, United States of America.

View Article and Find Full Text PDF
May 2016

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.

Proc Natl Acad Sci U S A 2015 Oct 21;112(40):12516-21. Epub 2015 Sep 21.

Regenerative Biology, Morgridge Institute for Research, Madison, WI 53715; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53705; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106

View Article and Find Full Text PDF
October 2015

Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments.

Nat Methods 2015 Oct 24;12(10):947-950. Epub 2015 Aug 24.

Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA.

View Article and Find Full Text PDF
October 2015

EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments.

Bioinformatics 2015 Aug 5;31(16):2614-22. Epub 2015 Apr 5.

Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA.

View Article and Find Full Text PDF
August 2015

A cost-effective RNA sequencing protocol for large-scale gene expression studies.

Sci Rep 2015 Apr 1;5:9570. Epub 2015 Apr 1.

1] Morgridge Institute for Research, Madison, Wisconsin, United States of America [2] Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America [3] Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America.

View Article and Find Full Text PDF
April 2015

Chromatin architecture reorganization during stem cell differentiation.

Nature 2015 Feb;518(7539):331-6

1] Ludwig Institute for Cancer Research, 9500 Gilman Drive, La Jolla, California 92093-0653, USA [2] University of California, San Diego School of Medicine, Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653, USA.

View Article and Find Full Text PDF
February 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

View Article and Find Full Text PDF
February 2015

Nonirradiated NOD,B6.SCID Il2rγ-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells.

Stem Cell Reports 2015 Feb 15;4(2):171-80. Epub 2015 Jan 15.

Morgridge Institute for Research, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address:

View Article and Find Full Text PDF
February 2015

Characterization and target identification of a DNA aptamer that labels pluripotent stem cells.

Cell Res 2015 Mar 16;25(3):390-3. Epub 2015 Jan 16.

1] Morgridge Institute for Research, Madison, WI, USA [2] Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA [3] Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA, USA.

View Article and Find Full Text PDF
March 2015

Array-based discovery of aptamer pairs.

Anal Chem 2015 Jan 11;87(1):821-8. Epub 2014 Dec 11.

Department of Mechanical Engineering, University of California-Santa Barbara , Santa Barbara, California 93106, United States.

View Article and Find Full Text PDF
January 2015

Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.

J Biol Chem 2015 Jan 8;290(5):3121-36. Epub 2014 Dec 8.

From the Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, the Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53706, the WiCell Institute, Madison, Wisconsin 53719,

View Article and Find Full Text PDF
January 2015

An expandable, inducible hemangioblast state regulated by fibroblast growth factor.

Stem Cell Reports 2014 Dec 13;3(6):1043-57. Epub 2014 Nov 13.

Morgridge Institute for Research, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address:

View Article and Find Full Text PDF
December 2014

Testing the bi-dimensional effects of attitudes on behavioural intentions and subsequent behaviour.

Br J Psychol 2015 Nov 29;106(4):656-74. Epub 2014 Nov 29.

School of Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.

View Article and Find Full Text PDF
November 2015

Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators.

Nat Commun 2014 Jul 14;5:4372. Epub 2014 Jul 14.

1] National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, Wisconsin 53715, USA [2] Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53707-7365, USA [3] Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, Wisconsin 53792, USA.

View Article and Find Full Text PDF
July 2014

MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers.

Bioinformatics 2014 Sep 28;30(18):2665-7. Epub 2014 May 28.

Regenerative Biology, Morgridge Institute for Research, Madison, WI 53707, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, Departments of Mechanical Engineering and Materials, University of California, Santa Barbara, CA 93106 and Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53706, USA.

View Article and Find Full Text PDF
September 2014

NANOG is multiply phosphorylated and directly modified by ERK2 and CDK1 in vitro.

Stem Cell Reports 2014 Jan 14;2(1):18-25. Epub 2014 Jan 14.

Stem Cells and Regenerative Medicine, Morgridge Institute for Research, Madison, WI 53715, USA ; Department of Cell & Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53706, USA ; Department of Molecular, Cellular & Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

View Article and Find Full Text PDF
January 2014

Gene targeting of human pluripotent stem cells by homologous recombination.

Methods Mol Biol 2014 ;1114:37-55

Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

View Article and Find Full Text PDF
October 2014

Quantitative selection and parallel characterization of aptamers.

Proc Natl Acad Sci U S A 2013 Nov 28;110(46):18460-5. Epub 2013 Oct 28.

Departments of Mechanical Engineering, Molecular, Cellular, and Developmental Biology, Chemistry, and Materials Department, University of California, Santa Barbara, CA 93106.

View Article and Find Full Text PDF
November 2013

Integrated module and gene-specific regulatory inference implicates upstream signaling networks.

PLoS Comput Biol 2013 17;9(10):e1003252. Epub 2013 Oct 17.

Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America ; Wisconsin Institute for Discovery, Madison, Wisconsin, United States of America.

View Article and Find Full Text PDF
May 2014

Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents.

PLoS One 2013 13;8(8):e71798. Epub 2013 Aug 13.

Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, USA.

View Article and Find Full Text PDF
May 2014

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis.

Proc Natl Acad Sci U S A 2013 Sep 12;110(39):15644-9. Epub 2013 Aug 12.

Morgridge Institute for Research, Madison, WI 53715.

View Article and Find Full Text PDF
September 2013

Single-round, multiplexed antibody mimetic design through mRNA display.

Angew Chem Int Ed Engl 2012 Dec 4;51(50):12449-53. Epub 2012 Nov 4.

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.

View Article and Find Full Text PDF
December 2012

Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions.

Nat Protoc 2012 Nov 25;7(11):2029-40. Epub 2012 Oct 25.

Center for Molecular Medicine, National Heart, Lung, and Blood Institute (NHLBI), Bethesda, Maryland, USA.

View Article and Find Full Text PDF
November 2012

Evidence that changes in social cognitions predict changes in self-reported driver behavior: Causal analyses of two-wave panel data.

Accid Anal Prev 2013 Jan 9;50:905-16. Epub 2012 Aug 9.

School of Psychological Sciences and Health, University of Strathclyde, UK.

View Article and Find Full Text PDF
January 2013

Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets.

Anal Chem 2012 Jun 8;84(12):5365-71. Epub 2012 Jun 8.

Interdepartmental Program in Biomolecular Science and Engineering, University of California Santa Barbara, Santa Barbara, California 93106, USA.

View Article and Find Full Text PDF
June 2012

Instant spectral assignment for advanced decision tree-driven mass spectrometry.

Proc Natl Acad Sci U S A 2012 May 14;109(22):8411-6. Epub 2012 May 14.

Department of Chemistry, University of Wisconsin, Madison, WI 53706, USA.

View Article and Find Full Text PDF
May 2012

Phosphorylation regulates human OCT4.

Proc Natl Acad Sci U S A 2012 May 2;109(19):7162-8. Epub 2012 Apr 2.

Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706-1532, USA.

View Article and Find Full Text PDF
May 2012