James A McCubrey

James A McCubrey

UNVERIFIED PROFILE

Are you James A McCubrey?   Register this Author

Register author
James A McCubrey

James A McCubrey

Publications by authors named "James A McCubrey"

Are you James A McCubrey?   Register this Author

100Publications

2006Reads

20Profile Views

Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells.

Biochim Biophys Acta Mol Cell Res 2019 Aug 27;1866(8):1322-1337. Epub 2019 Mar 27.

Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, BO, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2019.03.013DOI Listing
August 2019

Antitumor Mechanism of the Essential Oils from Two Succulent Plants in Multidrug Resistance Leukemia Cell.

Pharmaceuticals (Basel) 2019 Aug 26;12(3). Epub 2019 Aug 26.

Department of Biological, Chemical and Pharmaceutical Science and Technology (STEBICEF), University of Palermo, 90128 Palermo, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ph12030124DOI Listing
August 2019

miRNAs and their roles in KSHV pathogenesis.

Virus Res 2019 06 2;266:15-24. Epub 2019 Apr 2.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, United States. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01681702193009
Publisher Site
http://dx.doi.org/10.1016/j.virusres.2019.03.024DOI Listing
June 2019

The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response.

Cancers (Basel) 2019 May 6;11(5). Epub 2019 May 6.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11050629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562458PMC
May 2019

Nuclear phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular, and fertility disorders.

J Lipid Res 2019 02 4;60(2):312-317. Epub 2018 Oct 4.

Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy

View Article

Download full-text PDF

Source
http://www.jlr.org/lookup/doi/10.1194/jlr.R089763
Publisher Site
http://dx.doi.org/10.1194/jlr.R089763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358293PMC
February 2019

Targeting the phosphatidylinositol 3-kinase/Akt/mechanistic target of rapamycin signaling pathway in B-lineage acute lymphoblastic leukemia: An update.

J Cell Physiol 2018 10 18;233(10):6440-6454. Epub 2018 Apr 18.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.26539DOI Listing
October 2018

Targeting GSK3 signaling as a potential therapy of neurodegenerative diseases and aging.

Expert Opin Ther Targets 2018 10 26;22(10):833-848. Epub 2018 Sep 26.

a Department of Molecular Physiology and Neurobiology , University of Wroclaw , Wroclaw , Poland.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14728222.2018.1
Publisher Site
http://dx.doi.org/10.1080/14728222.2018.1526925DOI Listing
October 2018

Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging.

Aging (Albany NY) 2018 10;10(10):2911-2934

Department of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, 41124, Italy.

View Article

Download full-text PDF

Source
http://www.aging-us.com/article/101599/text
Publisher Site
http://dx.doi.org/10.18632/aging.101599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224265PMC
October 2018

Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines.

Adv Biol Regul 2018 08 18;69:43-62. Epub 2018 May 18.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, 27834, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2018.05.002DOI Listing
August 2018

Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update.

Int J Mol Sci 2018 Jun 26;19(7). Epub 2018 Jun 26.

Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19071878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073309PMC
June 2018

Metformin influences drug sensitivity in pancreatic cancer cells.

Adv Biol Regul 2018 05 12;68:13-30. Epub 2018 Feb 12.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2018.02.002DOI Listing
May 2018

Cutaneous melanoma: From pathogenesis to therapy (Review).

Int J Oncol 2018 Apr 27;52(4):1071-1080. Epub 2018 Feb 27.

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2018.4287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843392PMC
April 2018

Drug discovery targeting the mTOR pathway.

Clin Sci (Lond) 2018 03 9;132(5):543-568. Epub 2018 Mar 9.

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/CS20171158DOI Listing
March 2018

Impact of physical exercise in cancer survivors during and after antineoplastic treatments.

Oncotarget 2018 Mar 8;9(17):14005-14034. Epub 2018 Feb 8.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862633PMC
March 2018

Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases.

Oncotarget 2018 Mar 30;9(24):17220-17237. Epub 2018 Mar 30.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908319PMC
March 2018

Cardiovascular disease-related miRNAs expression: potential role as biomarkers and effects of training exercise.

Oncotarget 2018 Mar 30;9(24):17238-17254. Epub 2018 Mar 30.

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908320PMC
March 2018

Nuclear translocation of PKC-α is associated with cell cycle arrest and erythroid differentiation in myelodysplastic syndromes (MDSs).

FASEB J 2018 02 4;32(2):681-692. Epub 2018 Jan 4.

Cellular Signalling Laboratory, Institute of Human Anatomy, Dipartimento di Scienze Biomediche e NeuroMotorie, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201700690RDOI Listing
February 2018

Nuclear inositide signaling and cell cycle.

Adv Biol Regul 2018 01 23;67:1-6. Epub 2017 Oct 23.

Cellular Signalling Laboratory Department of Biomedical Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2017.10.008DOI Listing
January 2018

Bevacizumab in the treatment of NSCLC: patient selection and perspectives.

Lung Cancer (Auckl) 2017 14;8:259-269. Epub 2017 Dec 14.

Medical Oncology Department, San Vincenzo Hospital, Taormina (Messina), Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/LCTT.S110306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733913PMC
December 2017

Neuron-derived transthyretin modulates astrocytic glycolysis in hormone-independent manner.

Oncotarget 2017 Dec 20;8(63):106625-106638. Epub 2017 Nov 20.

Department of Physiology and Molecular Neurobiology, Faculty of Biological Sciences, University of Wroclaw, Wroclaw, Poland.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/22542
Publisher Site
http://dx.doi.org/10.18632/oncotarget.22542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739761PMC
December 2017

Dimeric and tetrameric forms of muscle fructose-1,6-bisphosphatase play different roles in the cell.

Oncotarget 2017 Dec 15;8(70):115420-115433. Epub 2017 Dec 15.

Department of Molecular Physiology and Neurobiology, University of Wroclaw, Wroclaw 50-335, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.23271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777782PMC
December 2017

Selective Activation of Nuclear PI-PLCbeta1 During Normal and Therapy-Related Differentiation.

Curr Pharm Des 2016 ;22(16):2345-8

Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, via Irnerio 48, 40126, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612822666160226132338DOI Listing
November 2017

Nuclear Inositide Signaling Via Phospholipase C.

J Cell Biochem 2017 08 25;118(8):1969-1978. Epub 2017 Apr 25.

Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, via Irnerio 48, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.25894DOI Listing
August 2017

Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma.

Adv Biol Regul 2017 08 6;65:59-76. Epub 2017 Jun 6.

Institute of Biomedicine and Molecular Immunology "Alberto Monroy", National Research Council (CNR), Palermo, Italy; Biomedic Department of Internal Medicine and Specialties (DiBiMIS), University of Palermo, Palermo, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2017.06.002DOI Listing
August 2017

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation.

Int J Oncol 2017 Aug 21;51(2):533-544. Epub 2017 Jun 21.

Institute of Biomedicine and Molecular Immunology 'Alberto Monroy', National Research Council (CNR), Palermo, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2017.4049DOI Listing
August 2017

GSK-3 signaling in health.

Adv Biol Regul 2017 08 1;65:1-4. Epub 2017 Jul 1.

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Via Irnerio, 48 I-40126 Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2017.06.004DOI Listing
August 2017

Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis.

Adv Biol Regul 2017 Jan 6;63:32-48. Epub 2016 Oct 6.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2016.10.001DOI Listing
January 2017

PLC-β1 and cell differentiation: An insight into myogenesis and osteogenesis.

Adv Biol Regul 2017 Jan 18;63:1-5. Epub 2016 Oct 18.

Cellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2016.10.005DOI Listing
January 2017

A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells.

Cell Cycle 2016 ;15(4):573-83

a Institute of Biomedicine and Molecular Immunology "Alberto Monroy,", National Research Council (CNR) , Palermo , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384101.2016.1138183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056616PMC
December 2016

The therapeutic potential of mTOR inhibitors in breast cancer.

Br J Clin Pharmacol 2016 11 10;82(5):1189-1212. Epub 2016 May 10.

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bcp.12958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061784PMC
November 2016

Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer.

Oncotarget 2016 Nov;7(45):72758-72766

Department of Biomedical and Biotechnological Sciences, Laboratory of Translational Oncology and Functional Genomics, Section of General and Clinical Pathology and Oncology, University of Catania, Catania, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.11805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341942PMC
November 2016

Nuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C.

J Cell Physiol 2016 Aug 28;231(8):1645-55. Epub 2015 Dec 28.

Department of Biomedical Sciences, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.25273DOI Listing
August 2016

Diagnostic value of neutrophil gelatinase-associated lipocalin/matrix metalloproteinase-9 pathway in transitional cell carcinoma of the bladder.

Tumour Biol 2016 Jul 26;37(7):9855-63. Epub 2016 Jan 26.

Epidemiology and Biostatistics Unit, CRO Aviano National Cancer Institute, via Gallini 2, 33081, Aviano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13277-016-4872-xDOI Listing
July 2016

Inositide-dependent signaling pathways as new therapeutic targets in myelodysplastic syndromes.

Expert Opin Ther Targets 2016 Jun 17;20(6):677-87. Epub 2015 Dec 17.

a Cellular Signalling Laboratory, Institute of Human Anatomy, Department of Biomedical and Neuromotor Sciences , University of Bologna , Bologna , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2016.1125885DOI Listing
June 2016

MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma.

Aging (Albany NY) 2016 05;8(5):933-44

Department of Biomedical and Biotechnological Sciences, Laboratory of Translational Oncology and Functional Genomics, Section of General and Clinical Pathology and Oncology, University of Catania, 95124, Catania, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.100951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931845PMC
May 2016

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy.

Biochim Biophys Acta 2016 Mar 14;1863(3):438-448. Epub 2015 Aug 14.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2015.08.010DOI Listing
March 2016

Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting.

Biochim Biophys Acta 2016 Mar 1;1863(3):449-463. Epub 2015 Sep 1.

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2015.08.015DOI Listing
March 2016

Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression.

Biochim Biophys Acta 2016 Mar 14;1863(3):483-489. Epub 2015 Sep 14.

Department of Biomedical and Biotechnological Sciences, Section of General & Clinical Pathology and Oncology, University of Catania, Catania, Italy. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01674889150031
Publisher Site
http://dx.doi.org/10.1016/j.bbamcr.2015.09.018DOI Listing
March 2016

Modulation of nuclear PI-PLCbeta1 during cell differentiation.

Adv Biol Regul 2016 Jan 26;60:1-5. Epub 2015 Oct 26.

Department of Biomedical and Neuromotor Sciences, Cellular Signalling Laboratory, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2015.10.008DOI Listing
January 2016

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells.

Adv Biol Regul 2015 Sep 17;59:65-81. Epub 2015 Jul 17.

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2015.06.003DOI Listing
September 2015

Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward blood.

Oncotarget 2015 May;6(13):10924-39

Stem Cell and Leukaemia Proteomics Laboratory, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484429PMC
http://dx.doi.org/10.18632/oncotarget.3454DOI Listing
May 2015

Signaling intermediates (MAPK and PI3K) as therapeutic targets in NSCLC.

Curr Pharm Des 2014 ;20(24):3944-57

Division of Medical Oncology A, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/13816128113196660763DOI Listing
March 2015

Current treatment strategies for inhibiting mTOR in cancer.

Trends Pharmacol Sci 2015 Feb 11;36(2):124-35. Epub 2014 Dec 11.

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2014.11.004DOI Listing
February 2015

Malignant melanoma in elderly patients: biological, surgical and medical issues.

Expert Rev Anticancer Ther 2015 Jan 24;15(1):101-8. Epub 2014 Sep 24.

Department of Biomedical Sciences, Section of Pathology and Oncology, Laboratory of Translational Oncology and Functional Genomics, University of Catania, 85 Androne Avenue, Catania 95124, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14737140.2015.961426DOI Listing
January 2015

Autophagy in acute leukemias: a double-edged sword with important therapeutic implications.

Biochim Biophys Acta 2015 Jan 2;1853(1):14-26. Epub 2014 Oct 2.

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2014.09.023DOI Listing
January 2015

PLC and PI3K/Akt/mTOR signalling in disease and cancer.

Adv Biol Regul 2015 Jan 26;57:10-6. Epub 2014 Nov 26.

Department of Biomedical and Neuromotor Sciences, Cellular Signalling Laboratory, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2014.10.004DOI Listing
January 2015

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells.

Oncotarget 2015 Jan;6(3):1707-22

Institute of Biomedicine and Molecular Immunology "Alberto Monroy", National Research Council, Palermo, Italy.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359326PMC
http://dx.doi.org/10.18632/oncotarget.2738DOI Listing
January 2015

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression.

Oncotarget 2014 Nov;5(22):11526-40

Cell Signaling Laboratory, Department of Biomedical Sciences, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294327PMC
http://dx.doi.org/10.18632/oncotarget.2578DOI Listing
November 2014

Targeting breast cancer initiating cells: advances in breast cancer research and therapy.

Adv Biol Regul 2014 Sep 22;56:81-107. Epub 2014 May 22.

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Brody Building 5N98C, Greenville, NC 27858, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2014.05.003DOI Listing
September 2014

Pancreatic cancer stem cells: association with cell surface markers, prognosis, resistance, metastasis and treatment.

Adv Biol Regul 2014 Sep 24;56:45-50. Epub 2014 May 24.

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2014.05.001DOI Listing
September 2014

NOTCH and PTEN in prostate cancer.

Adv Biol Regul 2014 Sep 22;56:51-65. Epub 2014 May 22.

Department of Oncology, Brody School of Medicine at East Carolina University, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2014.05.002DOI Listing
September 2014

Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (review).

Int J Oncol 2014 Sep 26;45(3):909-18. Epub 2014 Jun 26.

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2014.2525DOI Listing
September 2014

Foreword: "Targeting signaling pathways in stem cells".

Adv Biol Regul 2014 Sep 19;56:1-5. Epub 2014 Jul 19.

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2014.07.001DOI Listing
September 2014

Emerging targeted therapies for melanoma treatment (review).

Int J Oncol 2014 Aug 3;45(2):516-24. Epub 2014 Jun 3.

Laboratory of Translational Oncology and Functional Genomics, Section of General Pathology and Oncology, Department of Biomedical Sciences, University of Catania, I-95124 Catania, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2014.2481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091965PMC
August 2014

Analysis of the B-RafV600E mutation in cutaneous melanoma patients with occupational sun exposure.

Oncol Rep 2014 Mar 14;31(3):1079-82. Epub 2014 Jan 14.

Laboratory of Translational Oncology and Functional Genomics, Section of General Pathology and Oncology, Department of Bio-medical Sciences, University of Catania, Catania 95124, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/or.2014.2977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926654PMC
March 2014

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer.

Oncotarget 2014 Mar;5(6):1576-94

Department of Bio-medical Sciences, Section of Pathology and Oncology, Laboratory of Translational Oncology and Functional Genomics, University of Catania, Catania, (Italy);

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/1738
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039233PMC
http://dx.doi.org/10.18632/oncotarget.1738DOI Listing
March 2014

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy.

Adv Biol Regul 2014 Jan 8;54:176-96. Epub 2013 Oct 8.

Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbior.2013.09.013DOI Listing
January 2014

Nuclear PI-PLCβ1: an appraisal on targets and pathology.

Adv Biol Regul 2014 Jan 20;54:2-11. Epub 2013 Nov 20.

Department of Biomedical and Neuromotor Sciences, Cellular Signalling Laboratory, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22124926130009
Publisher Site
http://dx.doi.org/10.1016/j.jbior.2013.11.003DOI Listing
January 2014

Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia.

Expert Opin Ther Targets 2013 Aug 11;17(8):921-36. Epub 2013 Jun 11.

Institute of Molecular Genetics, National Research Council-Rizzoli Orthopedic Institute, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2013.808333DOI Listing
August 2013

K562 cell proliferation is modulated by PLCβ1 through a PKCα-mediated pathway.

Cell Cycle 2013 Jun 6;12(11):1713-21. Epub 2013 May 6.

Cellular Signaling Laboratory, Department of Biomedical Sciences, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.24806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713130PMC
June 2013

p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3.

Cell Cycle 2012 Dec 27;11(24):4579-88. Epub 2012 Nov 27.

Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.22852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562303PMC
December 2012

Recent discoveries in the cycling, growing and aging of the p53 field.

Aging (Albany NY) 2012 Dec;4(12):887-93

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, NC 27858, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615156PMC
http://dx.doi.org/10.18632/aging.100529DOI Listing
December 2012

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.

Oncotarget 2012 Dec;3(12):1522-32

V.N. Orekhovich Institute of Biomedical Chemistry RAMS, 10 Pogodinskaya Str., Moscow, Russia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681491PMC
http://dx.doi.org/10.18632/oncotarget.889DOI Listing
December 2012