Jakob Troppmair

Jakob Troppmair

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Jakob Troppmair

Jakob Troppmair

Publications by authors named "Jakob Troppmair"

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69Publications

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The Human G Protein-Coupled ATP Receptor P2Y Is Associated With IL-10 Driven Macrophage Differentiation.

Front Immunol 2019 9;10:1870. Epub 2019 Aug 9.

Immunotherapy Unit, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.3389/fimmu.2019.01870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695557PMC
August 2019

BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS.

Sci Adv 2019 08 14;5(8):eaav8463. Epub 2019 Aug 14.

Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1126/sciadv.aav8463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693913PMC
August 2019

Targeting the Architecture of Deregulated Protein Complexes in Cancer.

Adv Protein Chem Struct Biol 2018 18;111:101-132. Epub 2017 Aug 18.

Institute of Biochemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1016/bs.apcsb.2017.07.001DOI Listing
July 2019

Associations of Oxidative Stress and Postoperative Outcome in Liver Surgery with an Outlook to Future Potential Therapeutic Options.

Oxid Med Cell Longev 2019 13;2019:3950818. Epub 2019 Feb 13.

Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1155/2019/3950818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393879PMC
May 2019

Subcutaneous administration of a neutralizing IL-1β antibody prolongs limb allograft survival.

Am J Transplant 2018 08 7;18(8):2029-2042. Epub 2018 May 7.

Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.

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http://doi.wiley.com/10.1111/ajt.14765
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http://dx.doi.org/10.1111/ajt.14765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100092PMC
August 2018

The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells.

Mol Oncol 2018 06 5;12(6):869-882. Epub 2018 May 5.

Daniel Swarovski Research Laboratory, Department of Visceral-, Transplant- and Thoracic Surgery, Medical University of Innsbruck (MUI), Austria.

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http://doi.wiley.com/10.1002/1878-0261.12199
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http://dx.doi.org/10.1002/1878-0261.12199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983121PMC
June 2018

Predicting the future from the past: volatile markers for respiratory infections.

Eur Respir J 2017 05 25;49(5). Epub 2017 May 25.

Daniel-Swarovski Research Laboratory, Dept of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria

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http://dx.doi.org/10.1183/13993003.00264-2017DOI Listing
May 2017

A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines.

Curr Med Chem 2016 ;23(20):2112-31

Daniel Swarovski Research Laboratory, Department of Visceral-, Transplant- and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086670PMC
http://dx.doi.org/10.2174/0929867323666160510122913DOI Listing
February 2017

Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc.

J Biol Chem 2016 Nov 13;291(45):23557-23568. Epub 2016 Sep 13.

From the Daniel Swarovski Research Laboratory, Department of Visceral, Transplant, and Thoracic Surgery,

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http://dx.doi.org/10.1074/jbc.M116.752766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095410PMC
November 2016

Biopsychronology: A Method Using Live Tissue Staining to Image Cell Function in the Kidney.

Methods Mol Biol 2016 ;1397:81-90

Department of General and Surgical Critical Care Medicine, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1007/978-1-4939-3353-2_8DOI Listing
October 2016

cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.

Sci Rep 2016 Feb 12;6:20930. Epub 2016 Feb 12.

Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1038/srep20930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751440PMC
February 2016

Breath analysis for in vivo detection of pathogens related to ventilator-associated pneumonia in intensive care patients: a prospective pilot study.

J Breath Res 2015 Jan 5;9(1):016004. Epub 2015 Jan 5.

Breath Research Institute of the Leopold Franzens University of Innsbruck, Rathausplatz 4, A-6850 Dornbirn, Austria. Innsbruck Medical University, Anichstraße 35, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1088/1752-7155/9/1/016004DOI Listing
January 2015

Precursors for cytochrome P450 profiling breath tests from an in silico screening approach.

J Breath Res 2014 Sep 18;8(4):046001. Epub 2014 Sep 18.

Department of Theoretical Chemistry and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 80/82, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1088/1752-7155/8/4/046001DOI Listing
September 2014

Biopsychronology: live confocal imaging of biopsies to assess organ function.

Transpl Int 2014 Aug 17;27(8):868-76. Epub 2014 Jun 17.

Daniel Swarovski Research Laboratory, Department of Visceral-, Transplant- and Thoracic Surgery, Center of Operative Medicine, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1111/tri.12338DOI Listing
August 2014

Bilirubin rinse of the graft ameliorates ischemia reperfusion injury in heart transplantation.

Transpl Int 2014 May 5;27(5):504-13. Epub 2014 Mar 5.

Department of Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck, Innsbruck, Austria; Department of Surgery, Ludwig-Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.1111/tri.12278DOI Listing
May 2014

RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins.

Exp Cell Res 2013 Oct 7;319(17):2728-38. Epub 2013 Aug 7.

Daniel Swarovski Research Laboratory, Department of Visceral-, Transplant- and Thoracic Surgery, Innsbruck Medical University, Austria.

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http://dx.doi.org/10.1016/j.yexcr.2013.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809515PMC
October 2013

Lipocalin-2 as mediator of chemokine expression and granulocyte infiltration during ischemia and reperfusion.

Transpl Int 2013 Jul 23;26(7):761-9. Epub 2013 May 23.

Department of Visceral, Transplant and Thoracic Surgery, Daniel Swarovski Research Laboratory, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1111/tri.12116DOI Listing
July 2013

Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro.

Cancer Cell Int 2013 Jul 17;13(1):72. Epub 2013 Jul 17.

Breath Research Institute, Austrian Academy of Sciences, Rathausplatz 4, A-6850 Dornbirn, Austria.

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http://dx.doi.org/10.1186/1475-2867-13-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717104PMC
July 2013

Characterization of volatile metabolites taken up by or released from Streptococcus pneumoniae and Haemophilus influenzae by using GC-MS.

Microbiology 2012 Dec 11;158(Pt 12):3044-3053. Epub 2012 Oct 11.

University Clinic of Anesthesia, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1099/mic.0.062687-0DOI Listing
December 2012

Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?

Ann Intensive Care 2011 Sep 26;1(1):41. Epub 2011 Sep 26.

Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, A-1200 Vienna, Austria.

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http://dx.doi.org/10.1186/2110-5820-1-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224479PMC
September 2011

Mitochondrial ROS production under cellular stress: comparison of different detection methods.

Anal Bioanal Chem 2011 Jun 20;400(8):2383-90. Epub 2011 Feb 20.

Cardiac Surgery Research Laboratory, Department of Heart Surgery, Innsbruck Medical University (IMU), Innsbruck, Austria.

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http://link.springer.com/10.1007/s00216-011-4764-2
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http://dx.doi.org/10.1007/s00216-011-4764-2DOI Listing
June 2011

Cold ischemia contributes to the development of chronic rejection and mitochondrial injury after cardiac transplantation.

Transpl Int 2010 Dec;23(12):1282-92

Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Innsbruck Medical University, Anichstrasse 35, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1432-2277.2010.01126.xDOI Listing
December 2010

Complex patterns of mitochondrial dynamics in human pancreatic cells revealed by fluorescent confocal imaging.

J Cell Mol Med 2010 Jan 27;14(1-2):417-25. Epub 2009 Mar 27.

Daniel Swarovski Research Laboratory, Center of Operative Medicine, Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innrain, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00750.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837585PMC
January 2010

TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.

Cancer Epidemiol Biomarkers Prev 2010 Jan;19(1):182-95

Department of Operative Medicine, Center of Operative Medicine, Innsbruck Medical University, Innsbruck, Austria.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-09-0162DOI Listing
January 2010

Intracellular signaling pathways control mitochondrial events associated with the development of ischemia/ reperfusion-associated damage.

Transpl Int 2009 Sep 28;22(9):922-30. Epub 2009 Apr 28.

Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Innsbruck Medical University (IMU), Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1432-2277.2009.00883.xDOI Listing
September 2009

Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts.

Eur J Cardiothorac Surg 2009 Mar 23;35(3):515-20. Epub 2009 Jan 23.

Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.ejcts.2008.11.035DOI Listing
March 2009

Proliferation arrest in B-Raf mutant melanoma cell lines upon MAPK pathway activation.

J Invest Dermatol 2009 Feb 24;129(2):406-14. Epub 2008 Jul 24.

Klinik für Dermatologie, Venerologie und Allergologie, Julius-Maximilians-Universität Joseph-Schneider Str. 2, Würzburg, Germany.

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http://dx.doi.org/10.1038/jid.2008.214DOI Listing
February 2009

Release of volatile organic compounds from the lung cancer cell line NCI-H2087 in vitro.

Anticancer Res 2009 Jan;29(1):419-26

Department of Operative Medicine, Innsbruck Medical University, A-6020 Innsbruck, Austria.

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January 2009

Protein levels of heme oxygenase-1 during reperfusion in human kidney transplants with delayed graft function.

Clin Transplant 2008 Jul-Aug;22(4):418-23. Epub 2008 Feb 3.

Department of General and Transplant Surgery, D. Swarovski Research Lab, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1399-0012.2008.00800.xDOI Listing
December 2008

Cytoplasmic signaling in the control of mitochondrial uproar?

Cell Commun Signal 2008 Aug 19;6. Epub 2008 Aug 19.

Daniel Swarovski Research Laboratory, Innsbruck Medical University (IMU), Innrain 66, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1186/1478-811X-6-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546410PMC
August 2008

Increase of MCP-1 (CCL2) in myelin mutant Schwann cells is mediated by MEK-ERK signaling pathway.

Glia 2008 Jun;56(8):836-43

Department of Neurology, Developmental Neurobiology, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1002/glia.20657DOI Listing
June 2008

Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.

J Biol Chem 2008 May 15;283(18):12120-8. Epub 2008 Feb 15.

Institute of Pharmacology, Medical School Hannover, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1074/jbc.M800583200DOI Listing
May 2008

Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets.

Mol Cell Biol 2008 Apr 22;28(7):2304-13. Epub 2008 Jan 22.

Daniel Swarovski Research Laboratory, Department of General and Transplant Surgery, Innsbruck Medical University, Innrain 66, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1128/MCB.00683-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268412PMC
April 2008

Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.

Anticancer Res 2007 Nov-Dec;27(6B):3963-71

Institute of Biochemistry and Endocrinology, Veterinary Faculty, Justus-Liebig- University, Giessen, Germany.

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February 2008

Blockade of p38 MAPK inhibits chronic allograft vasculopathy.

Transplantation 2008 Jan;85(2):293-7

Department of General and Transplant Surgery, D. Swarovski Research Lab, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1097/TP.0b013e318160130fDOI Listing
January 2008

Bilirubin inhibits tumor cell growth via activation of ERK.

Cell Cycle 2007 Dec 7;6(24):3078-85. Epub 2007 Sep 7.

Department of General and Transplant Surgery, D. Swarovski Research Lab, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.4161/cc.6.24.5022DOI Listing
December 2007

Signaling through RAS-RAF-MEK-ERK: from basics to bedside.

Curr Med Chem 2007 ;14(5):601-23

Division of Hematology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.2174/092986707780059670DOI Listing
April 2007

Mitochondrial subpopulations and heterogeneity revealed by confocal imaging: possible physiological role?

Biochim Biophys Acta 2006 May-Jun;1757(5-6):686-91. Epub 2006 Apr 17.

Daniel Swarovski Research Laboratory, Innsbruck Medical University, Innrain 66, A-6020 Innsbruck, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S000527280600069
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http://dx.doi.org/10.1016/j.bbabio.2006.03.014DOI Listing
September 2006

Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.

Nat Neurosci 2005 Sep 21;8(9):1169-78. Epub 2005 Aug 21.

Institut für Klinische Neurobiologie, University of Würzburg, Josef Schneider Str. 11, D-97080 Würzburg, Germany.

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http://dx.doi.org/10.1038/nn1524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361767PMC
September 2005

Stress kinase signaling in cancer: fact or fiction?

Cancer Lett 2005 Jan;217(1):1-9

Institut für Medizinische Strahlenkunde und Zellforschung, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2004.08.003DOI Listing
January 2005

Tumor induction by activated JNK occurs through deregulation of cellular growth.

Cancer Lett 2004 Nov;215(1):113-24

Institut für Medizinische Strahlenkunde und Zellforschung (MSZ), University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2004.05.015DOI Listing
November 2004

Regulating cell survival by controlling cellular energy production: novel functions for ancient signaling pathways?

FEBS Lett 2004 Nov;577(1-2):1-4

Daniel-Swarovski-Research Laboratory (DSL), Department of General and Transplant Surgery, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.febslet.2004.10.021DOI Listing
November 2004

Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites.

J Biol Chem 2004 Apr 19;279(14):14074-86. Epub 2003 Dec 19.

Institute for Medical Radiation and Cell Research, University of Wuerzburg, 97078 Wuerzburg.

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http://dx.doi.org/10.1074/jbc.M309620200DOI Listing
April 2004

Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases.

Biochim Biophys Acta 2004 Mar;1644(2-3):149-58

Institut für Medizinische Strahlenkunde und Zellforschung (MSZ), Universität Würzburg, Versbacher Str. 5, 97078 Würzburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S016748890300181
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http://dx.doi.org/10.1016/j.bbamcr.2003.10.015DOI Listing
March 2004

Raf and the road to cell survival: a tale of bad spells, ring bearers and detours.

Biochem Pharmacol 2003 Oct;66(8):1341-5

Department of General and Transplantation Surgery, Daniel-Swarovski-Research Lab, University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1016/s0006-2952(03)00483-0DOI Listing
October 2003

Regulation of glycolysis by Raf protein serine/threonine kinases.

Adv Enzyme Regul 2002 ;42:317-32

Institut für Medizinische, Strahlenkunde und Zellforschung (MSZ), Universität Würzburg, Versbacher Str. 5, Germany.

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http://dx.doi.org/10.1016/s0065-2571(01)00036-xDOI Listing
December 2002

Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling.

J Biol Chem 2002 Nov 19;277(48):45892-7. Epub 2002 Sep 19.

Physiologisches Institut and the Institut für Medizinische Strahlenkunde und Zellforschung, Universität Würzburg, 97070 Würzburg, Germany.

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http://dx.doi.org/10.1074/jbc.M208851200DOI Listing
November 2002

Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype.

J Biol Chem 2002 Aug 30;277(33):29510-8. Epub 2002 May 30.

Institut für Medizinische Strahlenkunde und Zellforschung, Universität Würzburg, 97078 Würzburg, Germany.

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http://dx.doi.org/10.1074/jbc.M203010200DOI Listing
August 2002

Truncation of the neuritogenic peptide bP2(60-70) results in the generation of altered peptide ligands with the potential to interfere with T cell activation.

J Neuroimmunol 2002 Aug;129(1-2):97-105

Clinical Research Group for Multiple Sclerosis and Neuroimmunology, Department of Neurology, Julius-Maximilians-University, Würzburg, Germany.

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http://dx.doi.org/10.1016/s0165-5728(02)00183-2DOI Listing
August 2002

Regulation of glycolysis by Raf protein serine/threonine kinases.

Adv Enzyme Regul 2002 ;42:317-32

Institut für Medizinische, Strahlenkunde und Zellforschung (MSZ), Universität Würzburg, Versbacher Str. 5, Germany.

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http://dx.doi.org/10.1016/s0065-2571(01)00036-xDOI Listing
December 2002

Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling.

J Biol Chem 2002 Feb 4;277(8):6443-54. Epub 2001 Dec 4.

Department of Physiological Chemistry I, Theodor-Boveri Institut, University of Würzburg, 97094 Würzburg, Germany.

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http://dx.doi.org/10.1074/jbc.M110684200DOI Listing
February 2002