Jaime Merchan

Jaime Merchan

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Jaime Merchan

Jaime Merchan

Publications by authors named "Jaime Merchan"

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44Publications

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Molecular Effects of Stromal-Selective Targeting by uPAR-Retargeted Oncolytic Virus in Breast Cancer.

Mol Cancer Res 2017 10 5;15(10):1410-1420. Epub 2017 Jul 5.

Division of Hematology-Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682105PMC
October 2017

Targeting tumor vasculature through oncolytic virotherapy: recent advances.

Oncolytic Virother 2015 11;4:169-81. Epub 2015 Nov 11.

Division of Hematology-Oncology, Department of Medicine, University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL, USA.

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http://dx.doi.org/10.2147/OV.S66045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918394PMC
August 2016

2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation.

Mol Cancer Ther 2016 Feb 4;15(2):264-75. Epub 2015 Dec 4.

Department of Medicine, Division of Hematology-Oncology, University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center, Miami, Florida.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747846PMC
February 2016

In vivo anti-metastatic effects of uPAR retargeted measles virus in syngeneic and xenograft models of mammary cancer.

Breast Cancer Res Treat 2015 Jan 18;149(1):99-108. Epub 2014 Dec 18.

Division of Hematology-Oncology, University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center, 1475 NW 12th Avenue, Suite 3300, Miami, FL, 33136, USA.

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http://dx.doi.org/10.1007/s10549-014-3236-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302411PMC
January 2015

A phase II study of capecitabine plus docetaxel in gemcitabine-pretreated metastatic pancreatic cancer patients: CapTere.

Cancer Chemother Pharmacol 2014 Apr 23;73(4):839-45. Epub 2014 Feb 23.

Division of Hematology/Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Ave St 3300, Miami, FL, 33136, USA.

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http://link.springer.com/10.1007/s00280-014-2414-z
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http://dx.doi.org/10.1007/s00280-014-2414-zDOI Listing
April 2014

Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy.

Biochem Pharmacol 2013 May 13;85(10):1463-77. Epub 2013 Mar 13.

Sheila and David Fuente Graduate Program in Cancer Biology, University of Miami Miller School of Medicine, 1550 NW 10th Avenue, Fox Building #406, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.bcp.2013.02.037DOI Listing
May 2013

A phase II trial of nab-Paclitaxel as second-line therapy in patients with advanced pancreatic cancer.

Am J Clin Oncol 2013 Apr;36(2):151-6

*Department of Medicine, Division of Hematology/Oncology, Miller School of Medicine, University of Miami, Miami, FL †Department of Oncology, Johns Hopkins Singapore International Medical Center, Singapore, Republic of Singapore.

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http://dx.doi.org/10.1097/COC.0b013e3182436e8cDOI Listing
April 2013

Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells.

Mol Carcinog 2013 Mar 28;52(3):218-28. Epub 2011 Nov 28.

Herbert Irving Comprehensive Cancer Center, Division of Hematology/Oncology, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1002/mc.21846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980866PMC
March 2013

Phase II study of gemcitabine, oxaliplatin, and cetuximab in advanced pancreatic cancer.

Am J Clin Oncol 2012 Oct;35(5):446-50

Division of Hematology-Oncology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1097/COC.0b013e31821862fbDOI Listing
October 2012

Role of plasminogen activator inhibitor-1 in urokinase's paradoxical in vivo tumor suppressing or promoting effects.

Mol Cancer Res 2012 Oct 21;10(10):1271-81. Epub 2012 Aug 21.

Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495620PMC
October 2012

Sunitinib-induced microangiopathic hemolytic anemia with fatal outcome.

Am J Ther 2012 Jul;19(4):e143-5

Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.

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http://dx.doi.org/10.1097/MJT.0b013e3181eefe8bDOI Listing
July 2012

Targeted delivery of an antibody-mutant human endostatin fusion protein results in enhanced antitumor efficacy.

Mol Cancer Ther 2011 Apr 10;10(4):603-14. Epub 2011 Mar 10.

Department of Medicine, University of Miami School of Medicine and Sylvester Comprehensive Cancer Center, 1475 N.W. 12th Avenue (D8-4) Miami, FL 33136, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0804DOI Listing
April 2011

EUS visualization and direct celiac ganglia neurolysis predicts better pain relief in patients with pancreatic malignancy (with video).

Gastrointest Endosc 2011 Feb;73(2):267-74

Department of Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00165107100223
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http://dx.doi.org/10.1016/j.gie.2010.10.029DOI Listing
February 2011

Antiangiogenic activity of 2-deoxy-D-glucose.

PLoS One 2010 Oct 27;5(10):e13699. Epub 2010 Oct 27.

Department of Medicine, University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center, Miami, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013699PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965179PMC
October 2010

Single-session endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography for evaluation of pancreaticobiliary disorders.

Surg Endosc 2010 Jun 7;24(6):1447-50. Epub 2010 Jan 7.

Division of Gastroenterology, Miller School of Medicine, University of Miami, PO Box 016960, Miami, FL 33101, USA.

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http://link.springer.com/10.1007/s00464-009-0798-3
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http://dx.doi.org/10.1007/s00464-009-0798-3DOI Listing
June 2010

Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor.

Cancer Res 2009 Feb 10;69(4):1459-68. Epub 2009 Feb 10.

Division of Hematology-Oncology, University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739455PMC
February 2009

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.

J Natl Cancer Inst 2006 Jun;98(11):756-64

Department of Oncology, Mayo College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1093/jnci/djj208DOI Listing
June 2006

Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: potentiation by Cox-2 inhibition.

Int J Cancer 2005 Jan;113(3):490-8

Division of Hematology-Oncology, Department of Medicine, the Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/ijc.20595DOI Listing
January 2005

Antiangiogenic property of human thrombin.

Microvasc Res 2003 Jul;66(1):1-14

Division of Nephrology, Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/s0026-2862(03)00037-2DOI Listing
July 2003

Olivocochlear efferent innervation of the organ of corti in hypothyroid rats.

J Comp Neurol 2003 May;459(4):454-67

Departamento de Histología y Anatomía, Facultad de Medicina, Universidad Miguel Hernández, Alicante, Spain.

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http://dx.doi.org/10.1002/cne.10620DOI Listing
May 2003

Hypothyroidism prevents developmental neuronal loss during auditory organ development.

Neurosci Res 2003 Apr;45(4):401-8

Departamento de Histología y Anatomía, Facultad de Medicina, Universidad Miguel Hernández, Apdo. Correos 374, 03550 San Juan de Alicante, Spain.

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http://dx.doi.org/10.1016/s0168-0102(03)00009-9DOI Listing
April 2003

In vitro and in vivo induction of antiangiogenic activity by plasminogen activators and captopril.

J Natl Cancer Inst 2003 Mar;95(5):388-99

Division of Hematology-Oncology, Department of Medicine and the Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/jnci/95.5.388DOI Listing
March 2003

Renal cancer: molecular mechanisms and newer therapeutic options.

Curr Opin Nephrol Hypertens 2002 Jan;11(1):37-42

Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1097/00041552-200201000-00006DOI Listing
January 2002