Publications by authors named "Jaime H Cheah"

19Publications

Synthesis of Potent Cytotoxic Epidithiodiketopiperazines Designed for Derivatization.

J Org Chem 2020 Apr 19;85(7):4648-4662. Epub 2020 Mar 19.

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/acs.joc.9b03371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127967PMC
April 2020

Identification and local delivery of vasodilators for the reduction of ureteral contractions.

Nat Biomed Eng 2020 01 2;4(1):28-39. Epub 2019 Dec 2.

Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41551-019-0482-4DOI Listing
January 2020

Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives.

J Am Chem Soc 2019 09 30;141(36):14411-14420. Epub 2019 Aug 30.

Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

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http://dx.doi.org/10.1021/jacs.9b07397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743222PMC
September 2019

A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production.

Biochemistry 2018 05 3;57(19):2814-2827. Epub 2018 May 3.

Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b00378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231715PMC
May 2018

Concise Total Synthesis of (+)-Luteoalbusins A and B.

Org Lett 2015 Sep 25;17(17):4268-71. Epub 2015 Aug 25.

Department of Chemistry, Massachusetts Institute of Technology , 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/acs.orglett.5b02059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597594PMC
September 2015

Discovery of a Small-Molecule Probe for V-ATPase Function.

J Am Chem Soc 2015 Apr 20;137(16):5563-8. Epub 2015 Apr 20.

∥Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States.

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http://dx.doi.org/10.1021/jacs.5b02150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416280PMC
April 2015

NAMPT is the cellular target of STF-31-like small-molecule probes.

ACS Chem Biol 2014 Oct 7;9(10):2247-54. Epub 2014 Aug 7.

Center for the Science of Therapeutics and ∥Howard Hughes Medical Institute, Broad Institute , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.

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http://dx.doi.org/10.1021/cb500347pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201331PMC
October 2014

Regulation of ferroptotic cancer cell death by GPX4.

Cell 2014 Jan;156(1-2):317-331

Department of Biological Sciences, Columbia University, 1208 Northwest Corner Building, 12 Floor, 550 West 120 Street, MC 4846, New York, NY 10027, USA.

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http://dx.doi.org/10.1016/j.cell.2013.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076414PMC
January 2014

PKA modulates iron trafficking in the striatum via small GTPase, Rhes.

Neuroscience 2013 Dec 30;253:214-20. Epub 2013 Aug 30.

Department of Psychiatry and Pharmacology, Center for Neurobiology and Behavior, The Perlman School of Medicine at the University of Pennsylvania, 125 S 31 St. TRL Rm 2207, Philadelphia, PA 19104.

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http://dx.doi.org/10.1016/j.neuroscience.2013.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871862PMC
December 2013

Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity.

J Neurosci 2013 Feb;33(8):3582-7

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1497-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711661PMC
February 2013