Jacson K Shen

Jacson K Shen

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Jacson K Shen

Jacson K Shen

Publications by authors named "Jacson K Shen"

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26Publications

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Global Interest in Gender Affirmation Surgery: A Google Trends Analysis.

Plast Reconstr Surg 2019 01;143(1):254e-256e

The University of Sydney School of Medicine, Sydney, Australia Division of Plastic Surgery, Department of Surgery, University of Washington School of Medicine, Seattle, Wash.

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http://dx.doi.org/10.1097/PRS.0000000000005160DOI Listing
January 2019

CDK4 expression in chordoma: A potential therapeutic target.

J Orthop Res 2018 06 22;36(6):1581-1589. Epub 2017 Dec 22.

UCLA Orthopaedic Surgery, Sarcoma Biology Laboratory, 615 Charles E Young Dr. South, Biomedical Sciences Research Building, Room 410, Los Angeles, CA 90095.

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http://dx.doi.org/10.1002/jor.23819DOI Listing
June 2018

Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma.

Biochim Biophys Acta Mol Basis Dis 2018 May 13;1864(5 Pt A):1573-1582. Epub 2018 Feb 13.

Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, People's Republic of China; Sarcoma Biology Laboratory, UCLA Orthopaedic Surgery, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.02.004DOI Listing
May 2018

Noncoding RNA in drug resistant sarcoma.

Oncotarget 2017 Sep 6;8(40):69086-69104. Epub 2017 Jul 6.

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA.

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http://dx.doi.org/10.18632/oncotarget.19029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620323PMC
September 2017

Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma.

Sci Rep 2017 05 8;7(1):1580. Epub 2017 May 8.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-01763-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431504PMC
May 2017

Facial Layer-by-Layer Engineering of Upconversion Nanoparticles for Gene Delivery: Near-Infrared-Initiated Fluorescence Resonance Energy Transfer Tracking and Overcoming Drug Resistance in Ovarian Cancer.

ACS Appl Mater Interfaces 2017 Mar 21;9(9):7941-7949. Epub 2017 Feb 21.

Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acsami.6b15321DOI Listing
March 2017

Regulation of microRNA-1 (miR-1) expression in human cancer.

Biochim Biophys Acta Gene Regul Mech 2017 Feb 5;1860(2):227-232. Epub 2016 Dec 5.

Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China; Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2016.12.004DOI Listing
February 2017

Aberrant DNA methylations in chondrosarcoma.

Epigenomics 2016 11 30;8(11):1519-1525. Epub 2016 Sep 30.

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital & Harvard Medical School, 55 Fruit Street, Jackson 1115, Boston, MA 02114, USA.

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http://dx.doi.org/10.2217/epi-2016-0071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289043PMC
November 2016

Evaluation of P-glycoprotein (Pgp) expression in human osteosarcoma by high-throughput tissue microarray.

J Orthop Res 2016 09 2;34(9):1606-12. Epub 2016 Feb 2.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114.

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http://dx.doi.org/10.1002/jor.23173DOI Listing
September 2016

The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer.

Oncotarget 2016 Jun;7(26):40846-40859

Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.

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http://dx.doi.org/10.18632/oncotarget.8519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130049PMC
June 2016

Pharmacokinetics and tolerability of NSC23925b, a novel P-glycoprotein inhibitor: preclinical study in mice and rats.

Sci Rep 2016 05 9;6:25659. Epub 2016 May 9.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/srep25659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860631PMC
May 2016

Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.

Cancer Lett 2016 Apr 21;373(1):109-118. Epub 2016 Jan 21.

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Jackson 1115, Boston, MA 02114, United States. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772675PMC
April 2016

Targeting EZH2-mediated methylation of H3K27 inhibits proliferation and migration of Synovial Sarcoma in vitro.

Sci Rep 2016 04 29;6:25239. Epub 2016 Apr 29.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, United States.

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http://dx.doi.org/10.1038/srep25239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850444PMC
April 2016

MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3.

Sci Rep 2016 Mar 2;6:22599. Epub 2016 Mar 2.

Orthopedic Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China.

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http://dx.doi.org/10.1038/srep22599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773864PMC
March 2016

Targeted cancer therapy; nanotechnology approaches for overcoming drug resistance.

Curr Med Chem 2015 ;22(11):1335-47

Massachusetts General Hospital and Harvard Medical School, 55 Fruit St, Jackson Building Room 1115, Boston, MA 02114, USA.

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http://dx.doi.org/10.2174/0929867322666150209151851DOI Listing
February 2016

The emerging roles and therapeutic potential of microRNAs (miRs) in liposarcoma.

Discov Med 2015 Nov;20(111):311-24

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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November 2015

Rhabdomyosarcoma: Advances in Molecular and Cellular Biology.

Sarcoma 2015 1;2015:232010. Epub 2015 Sep 1.

Department of Orthopaedic Surgery, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA ; Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1155/2015/232010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569767PMC
September 2015

CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma.

Sci Rep 2015 Jun 16;5:11365. Epub 2015 Jun 16.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.

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http://www.nature.com/articles/srep11365
Publisher Site
http://dx.doi.org/10.1038/srep11365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468826PMC
June 2015

Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer.

Oncotarget 2015 Apr;6(11):9313-26

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496219PMC
http://dx.doi.org/10.18632/oncotarget.3220DOI Listing
April 2015

MicroRNA-155 expression is independently predictive of outcome in chordoma.

Oncotarget 2015 Apr;6(11):9125-39

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496207PMC
http://dx.doi.org/10.18632/oncotarget.3273DOI Listing
April 2015

Targeting CDK11 in osteosarcoma cells using the CRISPR-Cas9 system.

J Orthop Res 2015 Feb 27;33(2):199-207. Epub 2014 Oct 27.

Department of Orthopaedic Surgery, Sarcoma Biology Laboratory, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Jackson 1115, 02114, Boston, Massachusetts; Department of Orthopaedic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jie Fang Avenue, 430022, Wuhan, China.

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http://doi.wiley.com/10.1002/jor.22745
Publisher Site
http://dx.doi.org/10.1002/jor.22745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304907PMC
February 2015

MicroRNA-1 (miR-1) inhibits chordoma cell migration and invasion by targeting slug.

J Orthop Res 2014 Aug 24;32(8):1075-82. Epub 2014 Apr 24.

Sarcoma Biology Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital, 50 Fruit Street, Jackson 1115, Boston, Massachusetts, 02114; Department of Orthopaedic Surgery, Nihon University School of Medicine, 30-1 Oyaguchikami-cho, Itabashi-ku, Tokyo, 173-8610, Japan.

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http://dx.doi.org/10.1002/jor.22632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123853PMC
August 2014

Targeting programmed cell death ligand 1 in osteosarcoma: an auto-commentary on therapeutic potential.

Oncoimmunology 2014;3(8):e954467. Epub 2014 Aug 3.

Sarcoma Biology Laboratory; Center for Sarcoma and Connective Tissue Oncology; Massachusetts General Hospital ; Boston, MA USA.

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http://dx.doi.org/10.4161/21624011.2014.954467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292524PMC
August 2014

Programmed cell death ligand 1 expression in osteosarcoma.

Cancer Immunol Res 2014 Jul 21;2(7):690-698. Epub 2014 Apr 21.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, United States.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082476PMC
July 2014