Publications by authors named "Jacques-Philippe Colletier"

59Publications

Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures.

Proc Natl Acad Sci U S A 2020 02 11;117(8):4142-4151. Epub 2020 Feb 11.

Université Grenoble Alpes, Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA), CNRS, Institut de Biologie Structurale (IBS), F-38000 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1821522117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049125PMC
February 2020

[Porins: a vital role and a social link within the bacterial biofilm of P. stuartii].

Med Sci (Paris) 2019 Apr 30;35(4):291-295. Epub 2019 Apr 30.

Université Grenoble-Alpes - CEA - CNRS UMR5075, Groupe Dynamique et cinétique des processus moléculaires (DYNAMOP), 71, rue des martyrs - CS 10090, 38044 Grenoble Cedex 9, France.

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https://www.medecinesciences.org/10.1051/medsci/2019059
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http://dx.doi.org/10.1051/medsci/2019059DOI Listing
April 2019

Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides.

Nat Commun 2018 08 29;9(1):3512. Epub 2018 Aug 29.

Department of Biology, Technion-Israel Institute of Technology, Haifa, 3200003, Israel.

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http://www.nature.com/articles/s41467-018-05490-0
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http://dx.doi.org/10.1038/s41467-018-05490-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115460PMC
August 2018

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis.

Molecules 2018 Mar 11;23(3). Epub 2018 Mar 11.

Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII 27-31, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.3390/molecules23030634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017698PMC
March 2018

Porin self-association enables cell-to-cell contact in floating communities.

Proc Natl Acad Sci U S A 2018 03 23;115(10):E2220-E2228. Epub 2018 Feb 23.

Institut de Biologie Structurale (IBS), University of Grenoble Alpes (UGA), Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), 38000 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1714582115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878009PMC
March 2018

Providencia stuartii form biofilms and floating communities of cells that display high resistance to environmental insults.

PLoS One 2017 23;12(3):e0174213. Epub 2017 Mar 23.

Institut de Biologie Structurale, Université Grenoble Alpes - Commissariat à l'Énergie Atomique - Centre National de la Recherche Scientifique, Grenoble, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363852PMC
August 2017

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.

Bioorg Med Chem 2017 01 19;25(2):633-645. Epub 2016 Nov 19.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.11.032DOI Listing
January 2017

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.

Bioorg Med Chem 2015 Aug 14;23(15):4442-4452. Epub 2015 Jun 14.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.06.010DOI Listing
August 2015

Varied Probability of Staying Collapsed/Extended at the Conformational Equilibrium of Monomeric Aβ40 and Aβ42.

Sci Rep 2015 Jun 5;5:11024. Epub 2015 Jun 5.

CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai 201203, China.

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http://dx.doi.org/10.1038/srep11024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603783PMC
June 2015

Understanding Voltage Gating of Providencia stuartii Porins at Atomic Level.

PLoS Comput Biol 2015 May 8;11(5):e1004255. Epub 2015 May 8.

CAS Key Laboratory of Receptor Research, Drug Discovery and Design Centre, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, China.

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http://dx.doi.org/10.1371/journal.pcbi.1004255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425685PMC
May 2015

Hydration water mobility is enhanced around tau amyloid fibers.

Proc Natl Acad Sci U S A 2015 May 27;112(20):6365-70. Epub 2015 Apr 27.

Université Grenoble Alpes, CNRS, and Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Institut de Biologie Structurale, 38044 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1422824112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443308PMC
May 2015

Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.

J Med Chem 2014 Oct 29;57(19):8167-79. Epub 2014 Sep 29.

Faculty of Pharmacy, University of Ljubljana , Aškerčeva 7, 1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.1021/jm501195eDOI Listing
October 2014

Virus particle assembly into crystalline domains enabled by the coffee ring effect.

Soft Matter 2014 Aug;10(30):5458-62

European Synchrotron Radiation Facility, CS 40220, F-38043 Grenoble Cedex 9, France.

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http://dx.doi.org/10.1039/c4sm00414kDOI Listing
August 2014

Structure-guided simulations illuminate the mechanism of ATP transport through VDAC1.

Nat Struct Mol Biol 2014 Jul 8;21(7):626-32. Epub 2014 Jun 8.

1] Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [2] Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA.

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http://www.nature.com/articles/nsmb.2841
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http://dx.doi.org/10.1038/nsmb.2841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157756PMC
July 2014

Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry.

Chem Res Toxicol 2013 Feb 5;26(2):280-9. Epub 2013 Feb 5.

Institut de Biologie Structurale J.P. Ebel, Commissariat à l'Energie Atomique, 41, rue Jules Horowitz, F-38027 Grenoble, France.

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http://dx.doi.org/10.1021/tx3004505DOI Listing
February 2013

Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions.

Mol Biol Evol 2012 Jun 19;29(6):1683-94. Epub 2012 Jan 19.

Dynamop Group, Institut de Biologie Structurale J.-P. Ebel, CEA CNRS UJF, UMR 5075, Grenoble cedex 01, France.

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http://dx.doi.org/10.1093/molbev/mss015DOI Listing
June 2012

Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography.

ChemMedChem 2012 Mar 4;7(3):400-5. Epub 2011 Nov 4.

Equipe de Chimie Bio-organique, COBRA-CNRS UMR 6014 & FR 3038, Rue Lucien Tesnière, 76131 Mont-Saint-Aignan, France.

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http://dx.doi.org/10.1002/cmdc.201100438DOI Listing
March 2012

Molecular basis for amyloid-beta polymorphism.

Proc Natl Acad Sci U S A 2011 Oct 23;108(41):16938-43. Epub 2011 Sep 23.

Howard Hughes Medical Institute, Department of Biological Chemistry and Chemistry and Biochemistry, UCLA-DOE Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.1112600108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193189PMC
October 2011

Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations.

Protein Sci 2011 Jul 10;20(7):1114-8. Epub 2011 Jun 10.

Comissariat à l'Energie Atomique, Institut de Biologie Structurale, F-38054 Grenoble, France.

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http://dx.doi.org/10.1002/pro.661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149184PMC
July 2011

Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase.

Biophys J 2010 Dec;99(12):4003-11

Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1016/j.bpj.2010.10.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000518PMC
December 2010

Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation.

J Med Chem 2010 May;53(10):4002-8

Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale (CEA-CNRS-UJF), Grenoble, France.

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http://dx.doi.org/10.1021/jm901853bDOI Listing
May 2010

Temperature-dependent macromolecular X-ray crystallography.

Acta Crystallogr D Biol Crystallogr 2010 Apr 24;66(Pt 4):437-46. Epub 2010 Mar 24.

CEA, IBS, Laboratoire de Biophysique Moléculaire, F-38054 Grenoble, France.

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http://dx.doi.org/10.1107/S0907444910002702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852308PMC
April 2010

Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime.

J Med Chem 2009 Dec;52(23):7593-603

Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale Jean-Pierre Ebel, Commissariat à l'Energie Atomique, Centre National de la Recherche Scientifique, Université Joseph Fourier, 41 Rue Jules Horowitz, 38027 Grenoble, France.

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http://dx.doi.org/10.1021/jm900433tDOI Listing
December 2009

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating.

Proc Natl Acad Sci U S A 2008 Nov 6;105(46):17742-7. Epub 2008 Nov 6.

Department of Physiology, Cardiovascular Research Laboratories, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0809634105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584669PMC
November 2008

Shoot-and-Trap: use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography.

Proc Natl Acad Sci U S A 2008 Aug 13;105(33):11742-7. Epub 2008 Aug 13.

Laboratoire de Biophysique Moléculaire and Laboratoire de Cristallogenèse et de Cristallographie des Protéines, Centre National de la Recherche Scientifique, Université Joseph Fourier, F-38027 Grenoble, France.

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http://dx.doi.org/10.1073/pnas.0804828105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575335PMC
August 2008

Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics.

Biophys J 2008 Sep 23;95(5):2500-11. Epub 2008 May 23.

Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1529/biophysj.108.129601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517048PMC
September 2008

Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.

Acta Crystallogr D Biol Crystallogr 2007 Nov 17;63(Pt 11):1115-28. Epub 2007 Oct 17.

Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale Jean-Pierre EBEL, UMR 5075 CNRS-CEA-UJF, 38027 Grenoble, France.

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http://dx.doi.org/10.1107/S0907444907044472DOI Listing
November 2007

Mechanisms of cholinesterase inhibition by inorganic mercury.

FEBS J 2007 Apr 12;274(7):1849-61. Epub 2007 Mar 12.

ICBAS, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Portugal.

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http://dx.doi.org/10.1111/j.1742-4658.2007.05732.xDOI Listing
April 2007

Structural insights into substrate traffic and inhibition in acetylcholinesterase.

EMBO J 2006 Jun 8;25(12):2746-56. Epub 2006 Jun 8.

Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale (CEA/CNRS/UJF), Grenoble Cedex, France.

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http://dx.doi.org/10.1038/sj.emboj.7601175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500847PMC
June 2006

Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate.

Eur J Biochem 2004 Apr;271(7):1364-71

Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia.

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http://dx.doi.org/10.1111/j.1432-1033.2004.04048.xDOI Listing
April 2004

Encapsulation of enzymes in liposomes: high encapsulation efficiency and control of substrate permeability.

Artif Cells Blood Substit Immobil Biotechnol 2004 Feb;32(1):67-75

Groupe de Biophysique et de Biotechnologie des Protéines, IPBS-UMR 5089, Toulouse, France.

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http://dx.doi.org/10.1081/bio-120028669DOI Listing
February 2004

Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer.

BMC Biotechnol 2002 May 10;2. Epub 2002 May 10.

Laboratoire de Synthèse et Physicochimie des Molécules d'Intérêt Biologiques-Groupe de Biochimie des Protéines, Université Paul Sabatier, Toulouse, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC113741PMC
http://dx.doi.org/10.1186/1472-6750-2-9DOI Listing
May 2002