Jacques Remacle, PhD - European Commission - head of unit

Jacques Remacle

PhD

European Commission

head of unit

Luxembourg, Luxembourg | Belgium

Main Specialties: Public Health

Additional Specialties: Public Health, Health research, Genomics

Jacques Remacle, PhD - European Commission - head of unit

Jacques Remacle

PhD

Introduction

Primary Affiliation: European Commission - Luxembourg, Luxembourg , Belgium

Specialties:

Additional Specialties:

Publications

20Publications

356Reads

-Profile Views

1105PubMed Central Citations

The mammalian gene function resource: the International Knockout Mouse Consortium.

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012
69 Reads
98 Citations
3.070 Impact Factor

International network of cancer genome projects.

Authors:
Thomas J Hudson Warwick Anderson Axel Artez Anna D Barker Cindy Bell Rosa R Bernabé M K Bhan Fabien Calvo Iiro Eerola Daniela S Gerhard Alan Guttmacher Mark Guyer Fiona M Hemsley Jennifer L Jennings David Kerr Peter Klatt Patrik Kolar Jun Kusada David P Lane Frank Laplace Lu Youyong Gerd Nettekoven Brad Ozenberger Jane Peterson T S Rao Jacques Remacle Alan J Schafer Tatsuhiro Shibata Michael R Stratton Joseph G Vockley Koichi Watanabe Huanming Yang Matthew M F Yuen Bartha M Knoppers Martin Bobrow Anne Cambon-Thomsen Lynn G Dressler Stephanie O M Dyke Yann Joly Kazuto Kato Karen L Kennedy Pilar Nicolás Michael J Parker Emmanuelle Rial-Sebbag Carlos M Romeo-Casabona Kenna M Shaw Susan Wallace Georgia L Wiesner Nikolajs Zeps Peter Lichter Andrew V Biankin Christian Chabannon Lynda Chin Bruno Clément Enrique de Alava Françoise Degos Martin L Ferguson Peter Geary D Neil Hayes Thomas J Hudson Amber L Johns Arek Kasprzyk Hidewaki Nakagawa Robert Penny Miguel A Piris Rajiv Sarin Aldo Scarpa Tatsuhiro Shibata Marc van de Vijver P Andrew Futreal Hiroyuki Aburatani Mónica Bayés David D L Botwell Peter J Campbell Xavier Estivill Daniela S Gerhard Sean M Grimmond Ivo Gut Martin Hirst Carlos López-Otín Partha Majumder Marco Marra John D McPherson Hidewaki Nakagawa Zemin Ning Xose S Puente Yijun Ruan Tatsuhiro Shibata Michael R Stratton Hendrik G Stunnenberg Harold Swerdlow Victor E Velculescu Richard K Wilson Hong H Xue Liu Yang Paul T Spellman Gary D Bader Paul C Boutros Peter J Campbell Paul Flicek Gad Getz Roderic Guigó Guangwu Guo David Haussler Simon Heath Tim J Hubbard Tao Jiang Steven M Jones Qibin Li Nuria López-Bigas Ruibang Luo Lakshmi Muthuswamy B F Francis Ouellette John V Pearson Xose S Puente Victor Quesada Benjamin J Raphael Chris Sander Tatsuhiro Shibata Terence P Speed Lincoln D Stein Joshua M Stuart Jon W Teague Yasushi Totoki Tatsuhiko Tsunoda Alfonso Valencia David A Wheeler Honglong Wu Shancen Zhao Guangyu Zhou Lincoln D Stein Roderic Guigó Tim J Hubbard Yann Joly Steven M Jones Arek Kasprzyk Mark Lathrop Nuria López-Bigas B F Francis Ouellette Paul T Spellman Jon W Teague Gilles Thomas Alfonso Valencia Teruhiko Yoshida Karen L Kennedy Myles Axton Stephanie O M Dyke P Andrew Futreal Daniela S Gerhard Chris Gunter Mark Guyer Thomas J Hudson John D McPherson Linda J Miller Brad Ozenberger Kenna M Shaw Arek Kasprzyk Lincoln D Stein Junjun Zhang Syed A Haider Jianxin Wang Christina K Yung Anthony Cros Anthony Cross Yong Liang Saravanamuttu Gnaneshan Jonathan Guberman Jack Hsu Martin Bobrow Don R C Chalmers Karl W Hasel Yann Joly Terry S H Kaan Karen L Kennedy Bartha M Knoppers William W Lowrance Tohru Masui Pilar Nicolás Emmanuelle Rial-Sebbag Laura Lyman Rodriguez Catherine Vergely Teruhiko Yoshida Sean M Grimmond Andrew V Biankin David D L Bowtell Nicole Cloonan Anna deFazio James R Eshleman Dariush Etemadmoghadam Brooke B Gardiner Brooke A Gardiner James G Kench Aldo Scarpa Robert L Sutherland Margaret A Tempero Nicola J Waddell Peter J Wilson John D McPherson Steve Gallinger Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Debabrata Mukhopadhyay Lynda Chin Ronald A DePinho Sarah Thayer Lakshmi Muthuswamy Kamran Shazand Timothy Beck Michelle Sam Lee Timms Vanessa Ballin Youyong Lu Jiafu Ji Xiuqing Zhang Feng Chen Xueda Hu Guangyu Zhou Qi Yang Geng Tian Lianhai Zhang Xiaofang Xing Xianghong Li Zhenggang Zhu Yingyan Yu Jun Yu Huanming Yang Mark Lathrop Jörg Tost Paul Brennan Ivana Holcatova David Zaridze Alvis Brazma Lars Egevard Egor Prokhortchouk Rosamonde Elizabeth Banks Mathias Uhlén Anne Cambon-Thomsen Juris Viksna Fredrik Ponten Konstantin Skryabin Michael R Stratton P Andrew Futreal Ewan Birney Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Sancha Martin Jorge S Reis-Filho Andrea L Richardson Christos Sotiriou Hendrik G Stunnenberg Giles Thoms Marc van de Vijver Laura van't Veer Fabien Calvo Daniel Birnbaum Hélène Blanche Pascal Boucher Sandrine Boyault Christian Chabannon Ivo Gut Jocelyne D Masson-Jacquemier Mark Lathrop Iris Pauporté Xavier Pivot Anne Vincent-Salomon Eric Tabone Charles Theillet Gilles Thomas Jörg Tost Isabelle Treilleux Fabien Calvo Paulette Bioulac-Sage Bruno Clément Thomas Decaens Françoise Degos Dominique Franco Ivo Gut Marta Gut Simon Heath Mark Lathrop Didier Samuel Gilles Thomas Jessica Zucman-Rossi Peter Lichter Roland Eils Benedikt Brors Jan O Korbel Andrey Korshunov Pablo Landgraf Hans Lehrach Stefan Pfister Bernhard Radlwimmer Guido Reifenberger Michael D Taylor Christof von Kalle Partha P Majumder Rajiv Sarin T S Rao M K Bhan Aldo Scarpa Paolo Pederzoli Rita A Lawlor Massimo Delledonne Alberto Bardelli Andrew V Biankin Sean M Grimmond Thomas Gress David Klimstra Giuseppe Zamboni Tatsuhiro Shibata Yusuke Nakamura Hidewaki Nakagawa Jun Kusada Tatsuhiko Tsunoda Satoru Miyano Hiroyuki Aburatani Kazuto Kato Akihiro Fujimoto Teruhiko Yoshida Elias Campo Carlos López-Otín Xavier Estivill Roderic Guigó Silvia de Sanjosé Miguel A Piris Emili Montserrat Marcos González-Díaz Xose S Puente Pedro Jares Alfonso Valencia Heinz Himmelbauer Heinz Himmelbaue Victor Quesada Silvia Bea Michael R Stratton P Andrew Futreal Peter J Campbell Anne Vincent-Salomon Andrea L Richardson Jorge S Reis-Filho Marc van de Vijver Gilles Thomas Jocelyne D Masson-Jacquemier Samuel Aparicio Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Hendrik G Stunnenberg Laura van't Veer Douglas F Easton Paul T Spellman Sancha Martin Anna D Barker Lynda Chin Francis S Collins Carolyn C Compton Martin L Ferguson Daniela S Gerhard Gad Getz Chris Gunter Alan Guttmacher Mark Guyer D Neil Hayes Eric S Lander Brad Ozenberger Robert Penny Jane Peterson Chris Sander Kenna M Shaw Terence P Speed Paul T Spellman Joseph G Vockley David A Wheeler Richard K Wilson Thomas J Hudson Lynda Chin Bartha M Knoppers Eric S Lander Peter Lichter Lincoln D Stein Michael R Stratton Warwick Anderson Anna D Barker Cindy Bell Martin Bobrow Wylie Burke Francis S Collins Carolyn C Compton Ronald A DePinho Douglas F Easton P Andrew Futreal Daniela S Gerhard Anthony R Green Mark Guyer Stanley R Hamilton Tim J Hubbard Olli P Kallioniemi Karen L Kennedy Timothy J Ley Edison T Liu Youyong Lu Partha Majumder Marco Marra Brad Ozenberger Jane Peterson Alan J Schafer Paul T Spellman Hendrik G Stunnenberg Brandon J Wainwright Richard K Wilson Huanming Yang

Nature 2010 Apr;464(7291):993-8

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http://dx.doi.org/10.1038/nature08987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902243PMC
April 2010
89 Reads
594 Citations
42.351 Impact Factor

Megascience. 'Omics data sharing.

Science 2009 Oct;326(5950):234-6

U.K. Natural Environment Research Council (NERC), Environmental Bioinformatics Centre, NERC Centre for Ecology and Hydrology, Oxford, OX1 3SR, UK.

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http://dx.doi.org/10.1126/science.1180598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770171PMC
October 2009
29 Reads
49 Citations
31.480 Impact Factor

CTLA-4 interacts with STAT5 and inhibits STAT5-mediated transcription.

Immunology 2006 Mar;117(3):396-401

Laboratory for Experimental Haematology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1365-2567.2005.02313.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782240PMC
March 2006
9 Reads
4 Citations
3.800 Impact Factor

Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein.

Genes Cells 2005 Sep;10(9):897-906

Department of Developmental Biology, Flanders Interuniversity Institute for Biotechnology (VIB), University of Leuven, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1365-2443.2005.00887.xDOI Listing
September 2005
29 Reads
5 Citations
2.810 Impact Factor

Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression.

Hum Mol Genet 2003 Apr;12(8):869-77

Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

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http://dx.doi.org/10.1093/hmg/ddg098DOI Listing
April 2003
5 Reads
9 Citations
6.393 Impact Factor

Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells.

Proc Natl Acad Sci U S A 2001 Oct 25;98(21):11985-90. Epub 2001 Sep 25.

Department of Medical Nutrition, Karolinska Institute, Novum, S-141 86 Huddinge, Sweden.

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http://dx.doi.org/10.1073/pnas.211253898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC59754PMC
October 2001
12 Reads
16 Citations
9.810 Impact Factor

NF-kappaB is involved in the regulation of CD154 (CD40 ligand) expression in primary human T cells.

Clin Exp Immunol 2001 Aug;125(2):229-36

Laboratory for Experimental Hematology, University of Leuven, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906116PMC
http://dx.doi.org/10.1046/j.1365-2249.2001.01601.xDOI Listing
August 2001
7 Reads
17 Citations
3.040 Impact Factor

Region-specific activation of the Xenopus brachyury promoter involves active repression in ectoderm and endoderm: a study using transgenic frog embryos.

Development 2000 Jun;127(12):2729-39

Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

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June 2000
5 Reads
17 Citations
6.462 Impact Factor

TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.

J Biol Chem 2000 Jun;275(24):18586-93

Department of Cell Growth, Flanders Interuniversity Institute for Biotechnology, Campus Gasthuisberg, University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1074/jbc.M000531200DOI Listing
June 2000
13 Reads
42 Citations
4.573 Impact Factor

New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites.

EMBO J 1999 Sep;18(18):5073-84

Department of Cell Growth, Flanders Interuniversity Institute for Biotechnology (VIB), Laboratory of Molecular Biology (CELGEN), University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1093/emboj/18.18.5073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171578PMC
September 1999
5 Reads
76 Citations
10.434 Impact Factor

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.

J Biol Chem 1999 Jul;274(29):20489-98

Department of Cell Growth, Differentiation and Development (VIB-07), Flanders Interuniversity Institute for Biotechnology (VIB), Herestraat49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1074/jbc.274.29.20489DOI Listing
July 1999
7 Reads
116 Citations
4.573 Impact Factor

A novel expression cloning method to isolate mammalian transcription factors in Schizosaccharomyces pombe.

Nucleic Acids Res 1998 Nov;26(22):5223-4

Department of Cell Growth, Differentiation and Development, Flanders Interuniversity Institute for Biotechnology, University of Leuven, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC147969PMC
http://dx.doi.org/10.1093/nar/26.22.5223DOI Listing
November 1998
9 Reads
9.112 Impact Factor

Oct-1 is involved in the transcriptional repression of the von willebrand factor gene promoter.

Blood 1998 Aug;92(4):1247-58

INSERM U143, Unité de Recherches sur l'Hémostase et la Thrombose, Hôpital de Bicêtre, Bicêtre, France.

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August 1998
7 Reads
14 Citations
10.452 Impact Factor

Identical cis-acting elements and related trans-acting factors control activity of nonviral promoter in Schizosaccharomyces pombe and mammalian cells.

DNA Cell Biol 1998 Apr;17(4):349-58

Laboratory of Molecular Biology (CELGEN), University of Leuven, Belgium.

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http://dx.doi.org/10.1089/dna.1998.17.349DOI Listing
April 1998
13 Reads
2.060 Impact Factor

Datin, a yeast poly(dA:dT)-binding protein, behaves as an activator of the wild-type ILV1 promoter and interacts synergistically with Reb1p.

Mol Gen Genet 1998 Apr;258(1-2):95-103

Department of Genetics, Institute of Molecular Biology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s004380050711DOI Listing
April 1998
5 Reads
4 Citations

IL-12 up-regulates CD40 ligand (CD154) expression on human T cells.

J Immunol 1998 Feb;160(3):1166-72

Department of Pathophysiology, Faculty of Medicine, Catholic University of Leuven, Belgium.

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February 1998
10 Reads
15 Citations
4.922 Impact Factor

Three classes of mammalian transcription activation domain stimulate transcription in Schizosaccharomyces pombe.

EMBO J 1997 Sep;16(18):5722-9

Department of Cell Growth, Differentiation and Development (VIB-07), Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium.

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http://dx.doi.org/10.1093/emboj/16.18.5722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1170203PMC
September 1997
6 Reads
10 Citations
10.434 Impact Factor

Recombinant human chromogranin A: expression, purification and characterization of the N-terminal derived peptides.

Regul Pept 1995 Mar;56(1):71-88

Unité INSERM U-338 Biologie de la Communication Cellulaire, Strasbourg, France.

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http://dx.doi.org/10.1016/0167-0115(95)00008-yDOI Listing
March 1995
12 Reads
5 Citations
2.014 Impact Factor

A REB1-binding site is required for GCN4-independent ILV1 basal level transcription and can be functionally replaced by an ABF1-binding site.

Mol Cell Biol 1992 Dec;12(12):5516-26

Department of Yeast Genetics, Carlsberg Laboratory, Valby, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC360489PMC
http://dx.doi.org/10.1128/mcb.12.12.5516DOI Listing
December 1992
15 Reads
14 Citations
4.780 Impact Factor