Jacques Joubert

Jacques Joubert

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Jacques Joubert

Jacques Joubert

Publications by authors named "Jacques Joubert"

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Design, synthesis and evaluation of pentacycloundecane and hexacycloundecane propargylamine derivatives as multifunctional neuroprotective agents.

Eur J Med Chem 2019 Feb 22;163:83-94. Epub 2018 Nov 22.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183101
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http://dx.doi.org/10.1016/j.ejmech.2018.11.051DOI Listing
February 2019

ICARUSS: An effective model for risk factor management in stroke survivors.

Int J Stroke 2019 Feb 20:1747493019830582. Epub 2019 Feb 20.

5 Sir Charles Gairdner Hospital, Nedlands, Australia.

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http://journals.sagepub.com/doi/10.1177/1747493019830582
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http://dx.doi.org/10.1177/1747493019830582DOI Listing
February 2019

Bicyclic bis-heteroaryl derivatives as inhibitors of the α-synuclein protein: a patent evaluation of WO2018138088A1.

Authors:
Jacques Joubert

Expert Opin Ther Pat 2018 Dec 31;28(12):939-945. Epub 2018 Oct 31.

a Pharmaceutical Chemistry, School of Pharmacy , University of the Western Cape , Bellville , South Africa.

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https://www.tandfonline.com/doi/full/10.1080/13543776.2018.1
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http://dx.doi.org/10.1080/13543776.2018.1541234DOI Listing
December 2018

Recent Developments in Drug Design of NO-donor Hybrid Compounds.

Mini Rev Med Chem 2018 ;18(14):1175-1198

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville, South Africa.

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http://dx.doi.org/10.2174/1389557518666180416150005DOI Listing
July 2018

Microwave Optimized Synthesis of -(adamantan-1-yl)-4-[(adamantan-1-yl)-sulfamoyl]benzamide and Its Derivatives for Anti-Dengue Virus Activity.

Molecules 2018 07 10;23(7). Epub 2018 Jul 10.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Bellville 7530, South Africa.

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http://dx.doi.org/10.3390/molecules23071678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099921PMC
July 2018

Indazole derivatives and their therapeutic applications: a patent review (2013-2017).

Expert Opin Ther Pat 2018 06 11;28(6):441-453. Epub 2018 May 11.

a Pharmaceutical Chemistry, School of Pharmacy , University of the Western Cape , Bellville , South Africa.

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http://dx.doi.org/10.1080/13543776.2018.1472240DOI Listing
June 2018

Adamantane amine-linked chloroquinoline derivatives as chloroquine resistance modulating agents in Plasmodium falciparum.

Bioorg Med Chem Lett 2018 05 12;28(8):1287-1291. Epub 2018 Mar 12.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.03.026DOI Listing
May 2018

Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease.

Medchemcomm 2018 Feb 16;9(2):357-370. Epub 2018 Jan 16.

Pharmaceutical Chemistry , School of Pharmacy , University of the Western Cape , Private Bag X17 , Bellville 7535 , South Africa . Email: ; Tel: +27 21 959 2195.

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http://dx.doi.org/10.1039/c7md00569eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083799PMC
February 2018

Small Molecule Efflux Pump Inhibitors in Mycobacterium tuberculosis: A Rational Drug Design Perspective.

Mini Rev Med Chem 2018 ;18(1):72-86

University of Stellenbosh, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences Bellville, Bellville, Western Cape, South Africa.

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http://dx.doi.org/10.2174/1389557517666170510105506DOI Listing
January 2018

Synthesis and Biological Evaluations of NO-Donating Oxa- and Aza-Pentacycloundecane Derivatives as Potential Neuroprotective Candidates.

Molecules 2018 Jan 31;23(2). Epub 2018 Jan 31.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.3390/molecules23020308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017363PMC
January 2018

Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.

Eur J Med Chem 2017 Jan 15;125:853-864. Epub 2016 Sep 15.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville, South Africa.

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http://dx.doi.org/10.1016/j.ejmech.2016.09.041DOI Listing
January 2017

Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer's Disease Therapy.

Open Med Chem J 2017 31;11:24-37. Epub 2017 Jan 31.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.2174/1874104501711010024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418947PMC
January 2017

Polycyclic amines as chloroquine resistance modulating agents in Plasmodium falciparum.

Bioorg Med Chem Lett 2016 Feb 19;26(4):1151-5. Epub 2016 Jan 19.

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.1016/j.bmcl.2016.01.052DOI Listing
February 2016

Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond.

Future Med Chem 2015 ;7(5):609-29

Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.4155/fmc.15.12DOI Listing
January 2016

Tricycloundecane Derivatives as Potential N-Methyl-D-aspartate (NMDA) Receptor and Voltage-Gated Calcium Channel Modulators.

ChemMedChem 2015 Jul 26;10(7):1259-66. Epub 2015 May 26.

School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535 (South Africa).

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http://dx.doi.org/10.1002/cmdc.201500072DOI Listing
July 2015

Chronic non-communicable diseases--where to now in Africa?

Authors:
Jacques Joubert

J Neurol Sci 2015 Jan 21;348(1-2):3-5. Epub 2014 Nov 21.

Department of Neurology, St Vincent's Hospital, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2014.11.021DOI Listing
January 2015

Pentacycloundecylamines and conjugates thereof as chemosensitizers and reversed chloroquine agents.

Bioorg Med Chem Lett 2014 Dec 6;24(23):5516-9. Epub 2014 Oct 6.

School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.1016/j.bmcl.2014.09.088DOI Listing
December 2014

Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents.

Eur J Med Chem 2014 Jun 13;80:122-34. Epub 2014 Apr 13.

Pharmaceutical Chemistry, School of Pharmacy, University of The Western Cape, Private Bag X17, Bellville 7535, South Africa; Pharmaceutical Chemistry, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.04.039DOI Listing
June 2014

Small molecule fluorescent ligands as central nervous system imaging probes.

Mini Rev Med Chem 2013 Apr;13(5):682-96

School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.2174/1389557511313050005DOI Listing
April 2013

S-nitrosylation and attenuation of excessive calcium flux by pentacycloundecane derivatives.

Med Chem 2012 May;8(3):361-71

Pharmaceutical Chemistry and Centre for Human Metabonomics, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa.

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May 2012

Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs.

ChemMedChem 2012 Mar 3;7(3):375-84. Epub 2012 Feb 3.

School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://doi.wiley.com/10.1002/cmdc.201100559
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http://dx.doi.org/10.1002/cmdc.201100559DOI Listing
March 2012

Antioxidant properties of 4-quinolones and structurally related flavones.

Bioorg Med Chem 2012 Jan 8;20(2):809-18. Epub 2011 Dec 8.

Department of Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.

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http://dx.doi.org/10.1016/j.bmc.2011.11.068DOI Listing
January 2012

Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-D-aspartate receptor and voltage gated calcium channel ligands.

Eur J Med Chem 2011 Oct 11;46(10):5010-20. Epub 2011 Aug 11.

Pharmaceutical Chemistry, North-West University, Private Bag 6001, Potchefstroom 2520, South Africa.

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http://dx.doi.org/10.1016/j.ejmech.2011.08.008DOI Listing
October 2011

Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents.

Bioorg Med Chem 2011 Jul 24;19(13):3935-44. Epub 2011 May 24.

Department of Pharmaceutical Chemistry, North-West University, Potchefstroom, South Africa.

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http://dx.doi.org/10.1016/j.bmc.2011.05.034DOI Listing
July 2011

Novel nitric oxide synthase inhibitors: a patent review.

Expert Opin Ther Pat 2011 Apr 22;21(4):537-60. Epub 2011 Feb 22.

School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.1517/13543776.2011.556619DOI Listing
April 2011

Telestroke in stroke survivors.

Cerebrovasc Dis 2009 18;27 Suppl 4:28-35. Epub 2009 Jun 18.

Division of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1159/000213056DOI Listing
September 2009

The positive effect of integrated care on depressive symptoms in stroke survivors.

Cerebrovasc Dis 2008 15;26(2):199-205. Epub 2008 Jul 15.

Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1159/000145328DOI Listing
October 2008

Fluorescent polycyclic ligands for nitric oxide synthase (NOS) inhibition.

Bioorg Med Chem 2008 Oct 27;16(19):8952-8. Epub 2008 Aug 27.

Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag 6001, Potchefstroom 2520, South Africa.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896080077
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http://dx.doi.org/10.1016/j.bmc.2008.08.049DOI Listing
October 2008

Stroke in rural areas and small communities.

Stroke 2008 Jun 17;39(6):1920-8. Epub 2008 Apr 17.

National Ageing Research Institute, 34 Poplar Rd, Parkville, Vic, Australia.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.107.501643
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http://dx.doi.org/10.1161/STROKEAHA.107.501643DOI Listing
June 2008

Diversity of risk factors for stroke: the putative roles and mechanisms of depression and air pollution.

J Neurol Sci 2007 Nov 31;262(1-2):71-6. Epub 2007 Jul 31.

National Ageing Research Institute, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jns.2007.06.027DOI Listing
November 2007

Risk factor management and depression post-stroke: the value of an integrated model of care.

J Clin Neurosci 2006 Jan;13(1):84-90

Department of Neurology, Royal Melbourne Hospital, Parkville, Australia.

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http://dx.doi.org/10.1016/j.jocn.2005.07.003DOI Listing
January 2006

Diagnosing headache.

Authors:
Jacques Joubert

Aust Fam Physician 2005 Aug;34(8):621-5

Epworth and Royal Melbourne Hospitals, Victoria, Australia.

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August 2005

Migraine--diagnosis and treatment.

Authors:
Jacques Joubert

Aust Fam Physician 2005 Aug;34(8):627-32

Epworth and Royal Melbourne Hospitals, Victoria, Australia.

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August 2005