Publications by authors named "Jacques Colinge"

86Publications

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics.

Nucleic Acids Res 2020 06;48(10):e55

Institut de Recherche en Cancérologie de Montpellier, Inserm, F-34298 Montpellier, France.

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http://dx.doi.org/10.1093/nar/gkaa183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261168PMC
June 2020

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells.

Int J Cancer 2019 09 10;145(5):1299-1311. Epub 2019 Jun 10.

IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France.

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http://dx.doi.org/10.1002/ijc.32413DOI Listing
September 2019

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

Cancer Res 2017 05 10;77(10):2722-2734. Epub 2017 Mar 10.

IGMM, CNRS Univ. Montpellier, Montpellier, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0707DOI Listing
May 2017

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations.

J Proteome Res 2016 Feb 12;15(2):647-58. Epub 2016 Jan 12.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences , 1090 Vienna, Austria.

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http://dx.doi.org/10.1021/acs.jproteome.5b01066DOI Listing
February 2016

Gene essentiality and synthetic lethality in haploid human cells.

Science 2015 Nov 15;350(6264):1092-6. Epub 2015 Oct 15.

Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, Netherlands. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria. Cancer Genomics Center (CGC.nl), Plesmanlaan 121, 1066CX, Amsterdam, Netherlands.

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http://www.sciencemag.org/cgi/doi/10.1126/science.aac7557
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http://dx.doi.org/10.1126/science.aac7557DOI Listing
November 2015

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

Nat Methods 2015 Nov 21;12(11):1055-7. Epub 2015 Sep 21.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1038/nmeth.3590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629415PMC
November 2015

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity.

Cell Rep 2015 Jun 18;11(12):1919-28. Epub 2015 Jun 18.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria; Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508342PMC
June 2015

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics.

Mol Cancer Ther 2014 Nov 4;13(11):2751-62. Epub 2014 Sep 4.

Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), Vienna, Austria. Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-14
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http://dx.doi.org/10.1158/1535-7163.MCT-14-0152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221415PMC
November 2014

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma.

J Proteome Res 2014 Jun 6;13(6):2830-45. Epub 2014 May 6.

Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna , Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1021/pr401270yDOI Listing
June 2014

Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency.

J Allergy Clin Immunol 2014 Jun 17;133(6):1651-9.e12. Epub 2014 Apr 17.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.02.034DOI Listing
June 2014

Building and exploring an integrated human kinase network: global organization and medical entry points.

J Proteomics 2014 Jul 3;107:113-27. Epub 2014 Apr 3.

CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH-BT 25.3, 1090, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115268PMC
July 2014

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

Cell Rep 2013 Dec 19;5(6):1749-62. Epub 2013 Dec 19.

Department of Neuronal Cell Biology, Center for Brain Research, Medical University of Vienna, 1090 Vienna, Austria; Max-Planck-Institute for Developmental Biology, 72076 Tübingen, Germany; Department for Anatomy & Cell Biology, Ludwig-Maximilians-University, 80336 Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247130069
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http://dx.doi.org/10.1016/j.celrep.2013.11.023DOI Listing
December 2013

Systems Biology Analysis of Kinase Inhibitor Action in Leukemia Treatments.

Authors:
Jacques Colinge

Biomed Tech (Berl) 2013 08 7;58 Suppl 1. Epub 2013 Sep 7.

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http://dx.doi.org/10.1515/bmt-2013-4306DOI Listing
August 2013

Affinity purification strategies for proteomic analysis of transcription factor complexes.

J Proteome Res 2013 Sep 22;12(9):4018-27. Epub 2013 Aug 22.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria.

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http://dx.doi.org/10.1021/pr4003323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768224PMC
September 2013

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies.

J Proteome Res 2013 Sep 20;12(9):4005-17. Epub 2013 Aug 20.

Department of Protein Biochemistry and Proteomics, Technological Centre of the Palacký University, Centre of the Region Haná for Biotechnological and Agricultural Research, Olomouc, Czech Republic.

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http://dx.doi.org/10.1021/pr400309pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127982PMC
September 2013

Isobar(PTM): a software tool for the quantitative analysis of post-translationally modified proteins.

J Proteomics 2013 Sep 5;90:77-84. Epub 2013 Mar 5.

CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH-BT. 25.3, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.jprot.2013.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759844PMC
September 2013

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

Nat Methods 2013 Apr 3;10(4):307-14. Epub 2013 Mar 3.

Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nmeth.2400DOI Listing
April 2013

Deconvolution of targeted protein-protein interaction maps.

J Proteome Res 2012 Aug 10;11(8):4102-9. Epub 2012 Jul 10.

CeMM-Center for Molecular Medicine of the Austrian Academy of Sciences, AKH-BT 25.3, Lazarettgasse 14, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1021/pr300137nDOI Listing
August 2012

Systems biology analysis of protein-drug interactions.

Proteomics Clin Appl 2012 Jan 27;6(1-2):102-16. Epub 2011 Dec 27.

Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), Jacques Colinge, Vienna, Austria.

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http://doi.wiley.com/10.1002/prca.201100077
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http://dx.doi.org/10.1002/prca.201100077DOI Listing
January 2012

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

Mol Cancer Ther 2011 Oct 18;10(10):1846-56. Epub 2011 Jul 18.

Ce-M-M-Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0100DOI Listing
October 2011

General statistical modeling of data from protein relative expression isobaric tags.

J Proteome Res 2011 Jun 11;10(6):2758-66. Epub 2011 May 11.

CeMM , Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1021/pr1012784DOI Listing
June 2011

Initial characterization of the human central proteome.

BMC Syst Biol 2011 Jan 26;5:17. Epub 2011 Jan 26.

CeMM - Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 19/3, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1186/1752-0509-5-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039570PMC
January 2011

TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo.

J Immunol 2011 Feb 22;186(3):1608-17. Epub 2010 Dec 22.

Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.1001665DOI Listing
February 2011

A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.

PLoS Comput Biol 2010 Nov 18;6(11):e1001001. Epub 2010 Nov 18.

Research Center for Molecular Medicine of the Austrian Academy of Science, Vienna, Austria.

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http://dx.doi.org/10.1371/journal.pcbi.1001001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987840PMC
November 2010

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer.

Nat Chem Biol 2010 Apr 28;6(4):291-9. Epub 2010 Feb 28.

Department of Thoracic Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

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http://dx.doi.org/10.1038/nchembio.332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842457PMC
April 2010

Acid elution and one-dimensional shotgun analysis on an Orbitrap mass spectrometer: an application to drug affinity chromatography.

J Proteome Res 2009 Oct;8(10):4753-65

Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), Lazarettgasse 19, 1090 Vienna, Austria.

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http://pubs.acs.org/doi/abs/10.1021/pr900455x
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http://dx.doi.org/10.1021/pr900455xDOI Listing
October 2009

Charting the molecular network of the drug target Bcr-Abl.

Proc Natl Acad Sci U S A 2009 May 20;106(18):7414-9. Epub 2009 Apr 20.

Research Center for Molecular Medicine, Austrian Academy of Sciences, Lazarettgasse 19, 1090 Vienna, Austria.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0900653106
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http://dx.doi.org/10.1073/pnas.0900653106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670881PMC
May 2009

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

Nat Immunol 2009 Mar 21;10(3):266-72. Epub 2009 Jan 21.

Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

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http://dx.doi.org/10.1038/ni.1702DOI Listing
March 2009

Peptide fragment intensity statistical modeling.

Authors:
Jacques Colinge

Anal Chem 2007 Oct 23;79(19):7286-90. Epub 2007 Aug 23.

Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 19/3, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1021/ac070488nDOI Listing
October 2007

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.

Proc Natl Acad Sci U S A 2007 Aug 7;104(33):13283-8. Epub 2007 Aug 7.

Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 19, 1090 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.0702654104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940229PMC
August 2007

Assessing peptide de novo sequencing algorithms performance on large and diverse data sets.

Proteomics 2007 Sep;7(17):3051-4

Bioinformatics Department, Upper Austria University of Applied Sciences at Hagenberg, Hagenberg, Austria.

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http://dx.doi.org/10.1002/pmic.200700224DOI Listing
September 2007

Introduction to computational proteomics.

PLoS Comput Biol 2007 Jul;3(7):e114

Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1371/journal.pcbi.0030114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933459PMC
July 2007

InSilicoSpectro: an open-source proteomics library.

J Proteome Res 2006 Mar;5(3):619-24

Upper Austria University of Applied Sciences at Hagenberg, Bioinformatics Department, Hauptstrasse 117, A-4232 Hagenberg, Austria.

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http://dx.doi.org/10.1021/pr0504236DOI Listing
March 2006

Differential proteomics via probabilistic peptide identification scores.

Anal Chem 2005 Jan;77(2):596-606

GeneProt Inc.. 2 Pré-de-la-Fontaine, case postale 125, CH-1217 Meyrin 2, Geneva, Switzerland.

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http://dx.doi.org/10.1021/ac0488513DOI Listing
January 2005

OLAV-PMF: a novel scoring scheme for high-throughput peptide mass fingerprinting.

J Proteome Res 2004 Jan-Feb;3(1):55-60

Geneprot Inc, 2 rue Pré-de-la-Fontaine, CH-1217 Meyrin, Switzerland.

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http://dx.doi.org/10.1021/pr034055mDOI Listing
October 2004

OLAV: towards high-throughput tandem mass spectrometry data identification.

Proteomics 2003 Aug;3(8):1454-63

GeneProt Inc., Pré de la Fontaine 2, CH-1217 Meyrin, Switzerland.

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http://doi.wiley.com/10.1002/pmic.200300485
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http://dx.doi.org/10.1002/pmic.200300485DOI Listing
August 2003

Improved peptide charge state assignment.

Proteomics 2003 Aug;3(8):1434-40

GeneProt Inc., Pré de la Fontaine 2, CH-1217 Meyrin, Switzerland.

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http://doi.wiley.com/10.1002/pmic.200300489
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http://dx.doi.org/10.1002/pmic.200300489DOI Listing
August 2003