Jacques Cote

Jacques Cote

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Jacques Cote

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Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.

Cell Rep 2020 Mar;30(12):3996-4002.e4

Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, PR China; Structural Genomics Consortium and Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.03.003DOI Listing
March 2020

Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.

Elife 2020 Feb 28;9. Epub 2020 Feb 28.

LBCMCP, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, France.

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http://dx.doi.org/10.7554/eLife.53375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048395PMC
February 2020

Measurement and Analysis of Lysine Acetylation by KAT Complexes In Vitro and In Vivo.

Methods Mol Biol 2019 ;1983:57-77

St. Patrick Research Group in Basic Oncology, Quebec City, QC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-9434-2_5DOI Listing
January 2020

Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.

Structure 2020 Jan 8;28(1):105-110.e3. Epub 2019 Nov 8.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2019.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949404PMC
January 2020

Gcn5 and Esa1 function as histone crotonyltransferases to regulate crotonylation-dependent transcription.

J Biol Chem 2019 Dec 7;294(52):20122-20134. Epub 2019 Nov 7.

Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands

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http://dx.doi.org/10.1074/jbc.RA119.010302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937567PMC
December 2019

The Tumor Suppressor PALB2: Inside Out.

Trends Biochem Sci 2019 03 10;44(3):226-240. Epub 2019 Jan 10.

CHU de Québec Research Center, Oncology Division, 9 McMahon, Québec City, QC, G1R 3S3, Canada; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, Québec City, QC, G1V 0A6, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680004183021
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http://dx.doi.org/10.1016/j.tibs.2018.10.008DOI Listing
March 2019

Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection.

Proc Natl Acad Sci U S A 2018 10 17;115(40):10028-10033. Epub 2018 Sep 17.

St. Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du Centre Hospitalier Universitaire de Québec-Axe Oncologie, Québec City, QC G1R 3S3, Canada;

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http://dx.doi.org/10.1073/pnas.1806513115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176631PMC
October 2018

Molecular Architecture of the Essential Yeast Histone Acetyltransferase Complex NuA4 Redefines Its Multimodularity.

Mol Cell Biol 2018 05 16;38(9). Epub 2018 Apr 16.

Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.1128/MCB.00570-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902594PMC
May 2018

Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex.

Nat Commun 2018 03 20;9(1):1147. Epub 2018 Mar 20.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science & Technology of China, Hefei, 230026, China.

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http://dx.doi.org/10.1038/s41467-018-03504-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861120PMC
March 2018

Purification of Yeast Native Reagents for the Analysis of Chromatin Function-I: Nucleosomes for Reconstitution and Manipulation of Histone Marks.

Methods Mol Biol 2017 ;1528:39-51

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, CHU de Québec Research Center- Oncology axis, Hôtel-Dieu de Québec, 9 McMahon Street, Quebec City, QC, Canada, G1R 3S3.

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http://dx.doi.org/10.1007/978-1-4939-6630-1_3DOI Listing
January 2018

Purification of Yeast Native Reagents for the Analysis of Chromatin Function-II: Multiprotein Complexes and Biochemical Assays.

Methods Mol Biol 2017 ;1528:53-67

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, CHU de Québec Research Center- Oncology axis, Hôtel-Dieu de Québec, 9 McMahon Street, Quebec City, QC, Canada, G1R 3S3.

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http://dx.doi.org/10.1007/978-1-4939-6630-1_4DOI Listing
January 2018

Recognition of Histone H3K14 Acylation by MORF.

Structure 2017 04 9;25(4):650-654.e2. Epub 2017 Mar 9.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415407PMC
April 2017

Acetylation of PCNA Sliding Surface by Eco1 Promotes Genome Stability through Homologous Recombination.

Mol Cell 2017 Jan 1;65(1):78-90. Epub 2016 Dec 1.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie, Quebec City, QC G1R 3S3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.10.033DOI Listing
January 2017

Novel mechanism of PCNA control through acetylation of its sliding surface.

Mol Cell Oncol 2017 13;4(2):e1279724. Epub 2017 Jan 13.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie , Quebec City, QC, Canada.

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https://www.tandfonline.com/doi/full/10.1080/23723556.2017.1
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http://dx.doi.org/10.1080/23723556.2017.1279724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383363PMC
January 2017

Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

Mol Cell Biol 2016 11 28;36(22):2768-2781. Epub 2016 Oct 28.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie, Hôtel-Dieu de Québec, Québec City, Quebec, Canada

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http://dx.doi.org/10.1128/MCB.00112-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086519PMC
November 2016

DNA repair: Chromatin remodeling without H2A.Z?

Cell Cycle 2014 28;13(7):1059. Epub 2014 Feb 28.

Laval University Cancer Research Center; CHU de Québec Research Center-Oncology; Quebec City Quebec, Canada.

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http://dx.doi.org/10.4161/cc.28383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013155PMC
May 2016

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

Mol Cell 2016 05;62(3):409-421

St. Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Quebec City, QC G1R 3S3, Canada; Centre Hospitalier Universitaire de Québec Research Center and School of Medicine, Laval University, Quebec City, QC G1V 4G2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887106PMC
May 2016

TINTIN, at the interface of chromatin, transcription elongation, and mRNA processing.

RNA Biol 2015 ;12(5):486-9

a St-Patrick Research Group in Basic Oncology; Laval University Cancer Research Center; CHU de Quebec Research Center-Oncology Axis; Hôtel-Dieu de Québec (CHU de Québec) ; Quebec City , Quebec , Canada.

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http://www.tandfonline.com/doi/full/10.1080/15476286.2015.10
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http://dx.doi.org/10.1080/15476286.2015.1026032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615837PMC
February 2016

EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation.

Mol Cell 2016 Jan 6;61(1):27-38. Epub 2015 Dec 6.

Department of Biological Chemistry, David Geffen School of Medicine, UCLA, 351A Biomedical Sciences Research Building, 615 Charles E. Young Drive South, Los Angeles, CA 90095-1737, USA; The Molecular Biology Institute, UCLA, Paul D. Boyer Hall, 611 Charles E. Young Drive South, Los Angeles, CA 90095-1570, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.10.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707986PMC
January 2016

Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes.

Biochem J 2015 Dec 29;472(2):239-48. Epub 2015 Sep 29.

Department of Cancer Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, U.S.A.

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http://dx.doi.org/10.1042/BJ20150654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917874PMC
December 2015

A new companion of elongating RNA Polymerase II: TINTIN, an independent sub-module of NuA4/TIP60 for nucleosome transactions.

Transcription 2014 7;5(5):e995571. Epub 2015 Jan 7.

a St-Patrick Research Group in Basic Oncology ; Laval University Cancer Research Center and CHU de Quebec Research Center-Oncology Axis ; Hôtel-Dieu de Québec (CHU de Québec); Quebec City , QC Canada.

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http://dx.doi.org/10.1080/21541264.2014.995571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581353PMC
October 2015

A Scalable Genome-Editing-Based Approach for Mapping Multiprotein Complexes in Human Cells.

Cell Rep 2015 Oct 8;13(3):621-633. Epub 2015 Oct 8.

Centre Hospitalier Universitaire de Québec Research Center and Faculty of Medicine, Laval University, Quebec City, QC G1V 4G2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.09.009DOI Listing
October 2015

Eaf1 Links the NuA4 Histone Acetyltransferase Complex to Htz1 Incorporation and Regulation of Purine Biosynthesis.

Eukaryot Cell 2015 Jun 3;14(6):535-44. Epub 2015 Apr 3.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie, Hôtel-Dieu de Québec, Quebec City, Quebec, Canada

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http://dx.doi.org/10.1128/EC.00004-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452573PMC
June 2015

Systematic identification of signal integration by protein kinase A.

Proc Natl Acad Sci U S A 2015 Apr 23;112(14):4501-6. Epub 2015 Mar 23.

Département de Biologie, The Quebec Network for Research on Protein Function, Structure, and Engineering, Institut de Biologie Intégrative et des Systèmes,

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http://dx.doi.org/10.1073/pnas.1409938112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394313PMC
April 2015

Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling.

EMBO J 2014 Jun 19;33(12):1397-415. Epub 2014 May 19.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center Centre de Recherche du CHU de Québec-Axe Oncologie Hôtel-Dieu de Québec, Quebec City, QC, Canada

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http://dx.doi.org/10.15252/embj.201386433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194127PMC
June 2014

Histone target selection within chromatin: an exemplary case of teamwork.

Genes Dev 2014 May;28(10):1029-41

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie, Hôtel-Dieu de Québec, Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1101/gad.236331.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035532PMC
May 2014

Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes.

Epigenetics 2014 Feb 29;9(2):186-93. Epub 2013 Oct 29.

Department of Pharmacology; University of Colorado School of Medicine; Aurora, CO USA.

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http://dx.doi.org/10.4161/epi.26792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962528PMC
February 2014

Precise deposition of histone H2A.Z in chromatin for genome expression and maintenance.

Biochim Biophys Acta 2013 Mar-Apr;1819(3-4):290-302

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http://dx.doi.org/10.1016/j.bbagrm.2011.10.004DOI Listing
February 2014

mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases.

Proc Natl Acad Sci U S A 2013 Apr 9;110(17):E1641-50. Epub 2013 Apr 9.

Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON, Canada K1H 8M5.

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http://dx.doi.org/10.1073/pnas.1218515110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637784PMC
April 2013

Perceiving the epigenetic landscape through histone readers.

Nat Struct Mol Biol 2012 Dec;19(12):1218-27

Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1038/nsmb.2436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645987PMC
December 2012

A chromatin switch for chromosome condensation.

Dev Cell 2012 Dec;23(6):1127-8

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHU de Québec), 9 McMahon Street, Quebec City QC G1R 2J6, Canada.

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http://dx.doi.org/10.1016/j.devcel.2012.11.016DOI Listing
December 2012

Histone phosphorylation: a chromatin modification involved in diverse nuclear events.

Epigenetics 2012 Oct 4;7(10):1098-108. Epub 2012 Sep 4.

Laval University Cancer Research Center, Hôtel-Dieu de Québec, Quebec City, QC, Canada.

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http://dx.doi.org/10.4161/epi.21975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469451PMC
October 2012

MYST-family histone acetyltransferases: beyond chromatin.

Cell Mol Life Sci 2011 Apr 4;68(7):1147-56. Epub 2010 Dec 4.

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon Street, Quebec City, QC, G1R 2J6, Canada.

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http://dx.doi.org/10.1007/s00018-010-0599-9DOI Listing
April 2011

Histone chaperones: modulators of chromatin marks.

Mol Cell 2011 Mar;41(5):502-14

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon Street, Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1016/j.molcel.2011.02.013DOI Listing
March 2011

Epigenetic modifications in double-strand break DNA damage signaling and repair.

Clin Cancer Res 2010 Sep 7;16(18):4543-52. Epub 2010 Sep 7.

Laval University Cancer Research Center, Hôtel-Dieu de Québec, Quebec City, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940951PMC
September 2010

Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping.

DNA Repair (Amst) 2009 Dec 31;8(12):1452-61. Epub 2009 Oct 31.

Department of Pathology, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.dnarep.2009.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787662PMC
December 2009

Connection between histone H2A variants and chromatin remodeling complexes.

Biochem Cell Biol 2009 Feb;87(1):35-50

Laval University Cancer Research Center, Hotel-Dieu de Quebec, Quebec City, QCG1R2J6, Canada.

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http://dx.doi.org/10.1139/O08-140DOI Listing
February 2009

Histone H3 tail clipping regulates gene expression.

Nat Struct Mol Biol 2009 Jan 14;16(1):17-22. Epub 2008 Dec 14.

Gurdon Institute and Department of Pathology, Tennis Court Road, Cambridge CB2 1QN, UK.

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http://dx.doi.org/10.1038/nsmb.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350865PMC
January 2009

Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex.

J Biol Chem 2008 Oct 6;283(43):28817-26. Epub 2008 Aug 6.

Department of Medicine, Section of Nephrology, Boston University School of Medicine and Medical Center, Evans Biomedical Research Center, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1074/jbc.M801407200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570895PMC
October 2008

Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants.

Mol Cell Biol 2008 Apr 22;28(7):2257-70. Epub 2008 Jan 22.

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon St., Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1128/MCB.01755-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268442PMC
April 2008

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin.

Mol Cell 2007 Dec;28(6):1002-14

Laval University Cancer Research Center, Hôtel-Dieu de Québec, Centre Hospitalier Universitaire de Québec, 9 McMahon Street, Quebec City, QC G1R 2J6, Canada.

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http://dx.doi.org/10.1016/j.molcel.2007.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610362PMC
December 2007

Structure/function analysis of the phosphatidylinositol-3-kinase domain of yeast tra1.

Genetics 2007 Sep 29;177(1):151-66. Epub 2007 Jul 29.

Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A5C1, Canada.

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http://dx.doi.org/10.1534/genetics.107.074476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013730PMC
September 2007

Mortality and cancer experience of Quebec aluminum reduction plant workers. Part I: The reduction plants and coal tar pitch volatile (CTPV) exposure assessment.

J Occup Environ Med 2007 Sep;49(9):997-1008

Groupe de Recherche Interdisciplinaire en Santé, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1097/JOM.0b013e3181484cf3DOI Listing
September 2007

Functions of myst family histone acetyltransferases and their link to disease.

Subcell Biochem 2007 ;41:295-317

Laval University Cancer Research Center, Hôtel-Dieu de Québec, 9 McMahon Street, Quebec City QC, Canada.

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June 2007

Histone modifications in response to DNA damage.

Mutat Res 2007 May 21;618(1-2):81-90. Epub 2007 Jan 21.

Laval University Cancer Research Center, Hôtel-Dieu de Québec, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1016/j.mrfmmm.2006.09.009DOI Listing
May 2007

[Mystification and cleverness of tumor suppressors in nuclear functions].

Med Sci (Paris) 2006 Nov;22(11):919-21

Centre de Recherche en Cancérologie de l'Université Laval, Hôtel-Dieu de Québec (CHUQ), 9, Rue McMahon, Québec (Québec) G1R 2J6, Canada.

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http://dx.doi.org/10.1051/medsci/20062211919DOI Listing
November 2006

Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling.

Proc Natl Acad Sci U S A 2006 Sep 29;103(37):13771-6. Epub 2006 Aug 29.

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0511192103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564209PMC
September 2006

Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

Mol Cell Biol 2005 Oct;25(19):8430-43

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1128/MCB.25.19.8430-8443.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1265753PMC
October 2005

Dynamics of chromatin during the repair of DNA double-strand breaks.

Cell Cycle 2005 Oct 17;4(10):1373-6. Epub 2005 Oct 17.

Department of Biochemistry, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.4161/cc.4.10.2108DOI Listing
October 2005

Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.

Mol Cell Biol 2005 Sep;25(18):8179-90

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon Street, Quebec City, QC, Canada G1R 2J6.

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http://dx.doi.org/10.1128/MCB.25.18.8179-8190.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234332PMC
September 2005

The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the Enhancer of Polycomb A domain and chromodomain to acetylate nucleosomes.

Mol Cell Biol 2005 Jul;25(13):5535-42

Center for Gene Regulation, Department of Biochemistry & Molecular Biology, 108 Althouse Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-1014, USA.

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http://dx.doi.org/10.1128/MCB.25.13.5535-5542.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156996PMC
July 2005

Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites.

Mol Cell 2004 Dec;16(6):979-90

The Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650400758
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http://dx.doi.org/10.1016/j.molcel.2004.12.003DOI Listing
December 2004

Recruitment of the NuA4 complex poises the PHO5 promoter for chromatin remodeling and activation.

EMBO J 2004 Jul 3;23(13):2597-607. Epub 2004 Jun 3.

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), Quebec City, Canada.

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http://emboj.embopress.org/cgi/doi/10.1038/sj.emboj.7600230
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http://dx.doi.org/10.1038/sj.emboj.7600230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC449761PMC
July 2004

Identification and analysis of native HAT complexes.

Methods Enzymol 2004 ;377:154-67

University of Virgina School of Medicine, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1016/S0076-6879(03)77008-6DOI Listing
April 2004

The highly conserved and multifunctional NuA4 HAT complex.

Curr Opin Genet Dev 2004 Apr;14(2):147-54

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon Street, Quebec City, Qc G1R 2J6 Canada.

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http://dx.doi.org/10.1016/j.gde.2004.02.009DOI Listing
April 2004

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Mol Cell Biol 2004 Mar;24(5):1884-96

Laval University Cancer Research Center, Hôtel-Dieu de Québec, Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1128/mcb.24.5.1884-1896.2004DOI Listing
March 2004

Chromatin remodeling and the maintenance of genome integrity.

Biochim Biophys Acta 2004 Mar;1677(1-3):158-64

Centre de Recherche en Cancérologie de l'Université Laval, Hôtel-Dieu de Québec (CHUQ), 9 rue McMahon, Québec, Canada G1R 2J6.

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http://dx.doi.org/10.1016/j.bbaexp.2003.10.016DOI Listing
March 2004

Cellular machineries for chromosomal DNA repair.

Genes Dev 2004 Mar;18(6):602-16

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 01605, USA.

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http://dx.doi.org/10.1101/gad.1182704DOI Listing
March 2004

[The epigenetic code of histones].

Med Sci (Paris) 2003 Oct;19(10):955-9

Centre de recherche en cancérologie de l'Université Laval, Hôtel-Dieu de Québec (CHUQ), 9, rue McMahon, Québec, G1R 2J6, Canada.

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http://dx.doi.org/10.1051/medsci/20031910955DOI Listing
October 2003

The diverse functions of histone acetyltransferase complexes.

Trends Genet 2003 Jun;19(6):321-9

Department of Biochemistry and Molecular Biology, Howard Hughes Medical Institute, Penn State University, University Park, PA 16803, USA.

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http://dx.doi.org/10.1016/S0168-9525(03)00115-XDOI Listing
June 2003

Opposite role of yeast ING family members in p53-dependent transcriptional activation.

J Biol Chem 2003 May 2;278(21):19171-5. Epub 2003 Apr 2.

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1074/jbc.C300036200DOI Listing
May 2003

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

J Biol Chem 2002 Aug 3;277(34):30421-4. Epub 2002 Jul 3.

Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 9 McMahon Street, Quebec City, Quebec G1R 2J6, Canada.

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http://dx.doi.org/10.1074/jbc.C200366200DOI Listing
August 2002