Jacqueline Ramirez

Jacqueline Ramirez

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Jacqueline Ramirez

Jacqueline Ramirez

Publications by authors named "Jacqueline Ramirez"

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Prolonged Pharmacokinetic Interaction Between Capecitabine and a CYP2C9 Substrate, Celecoxib.

J Clin Pharmacol 2019 Dec 5;59(12):1632-1640. Epub 2019 Jul 5.

Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1002/jcph.1476DOI Listing
December 2019

Multilingual Diversity in the Field of Applied Behavior Analysis and Autism: A Brief Review and Discussion of Future Directions.

Behav Anal Pract 2019 Dec 5;12(4):795-804. Epub 2019 Aug 5.

2Department of Psychology, University of Southern California and FirstSteps for Kids, SGM 501, Los Angeles, CA 90089 USA.

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http://dx.doi.org/10.1007/s40617-019-00382-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834820PMC
December 2019

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children.

Front Pharmacol 2016 16;7:437. Epub 2016 Nov 16.

Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University West Lafayette, IN, USA.

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http://dx.doi.org/10.3389/fphar.2016.00437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110524PMC
November 2016

In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7.

Xenobiotica 2015 8;45(11):990-8. Epub 2015 Jun 8.

a Department of Medicine , University of Chicago , Chicago , IL , USA.

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http://dx.doi.org/10.3109/00498254.2015.1038743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844176PMC
June 2016

Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.

Drug Metab Dispos 2015 Jul 13;43(7):928-35. Epub 2015 Apr 13.

Department of Medicine, University of Chicago, Chicago, Illinois

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http://dx.doi.org/10.1124/dmd.115.063271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468433PMC
July 2015

Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.

J Clin Oncol 2014 Aug 23;32(22):2328-34. Epub 2014 Jun 23.

Federico Innocenti, Richard L. Schilsky, Jacqueline Ramírez, Linda Janisch, Samir Undevia, Larry K. House, Soma Das, Kehua Wu, Michelle Turcich, Theodore Karrison, Michael L. Maitland, Ravi Salgia, and Mark J. Ratain, University of Chicago, Chicago; and Robert Marsh, NorthShore University Health System, Evanston, IL.

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http://dx.doi.org/10.1200/JCO.2014.55.2307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105486PMC
August 2014

A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.

Pharmacogenet Genomics 2014 Feb;24(2):129-32

aDepartment of Medicine, The University of Chicago, Chicago, Illinois bDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901533PMC
February 2014

Evaluation of utility of pharmacokinetic studies in phase I trials of two oncology drugs.

Clin Cancer Res 2013 Nov 20;19(21):6039-43. Epub 2013 Sep 20.

Authors' Affiliations: Departments of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832109PMC
November 2013

Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene.

J Pharmacol Exp Ther 2013 Oct 6;347(1):181-92. Epub 2013 Aug 6.

Institute of Clinical Pharmacology, University Medical Center, Georg-August-Universität Göttingen, Germany (V.P.O., K.B., K.J., J.B., M.V.T.); and Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois (J.R., M.J.R.).

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http://dx.doi.org/10.1124/jpet.113.206359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781413PMC
October 2013

SNPs affecting serum metabolomic traits may regulate gene transcription and lipid accumulation in the liver.

Metabolism 2012 Nov 26;61(11):1523-7. Epub 2012 Jun 26.

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.metabol.2012.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867007PMC
November 2012

The effect of thalidomide on the pharmacokinetics of irinotecan and metabolites in advanced solid tumor patients.

Cancer Chemother Pharmacol 2011 Dec 23;68(6):1629-32. Epub 2011 Aug 23.

Department of Medicine, Section of Hematology/Oncology, University of Chicago, 5841 S Maryland Avenue, MC2115, Chicago, IL 60637, USA.

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http://link.springer.com/10.1007/s00280-011-1727-4
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http://dx.doi.org/10.1007/s00280-011-1727-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259680PMC
December 2011

Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors.

Br J Clin Pharmacol 2011 Jun;71(6):917-20

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1111/j.1365-2125.2011.03911.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099378PMC
June 2011

Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions.

Cancer Res 2011 Apr 3;71(7):2423-7. Epub 2011 Feb 3.

Department of Medicine; Comprehensive Cancer Center, and Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070854PMC
April 2011

A pharmacogenetic study of vorinostat glucuronidation.

Pharmacogenet Genomics 2010 Oct;20(10):638-41

Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833e1b37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636562PMC
October 2010

Juvenile idiopathic arthritis and Wegener's granulomatosis--causal or casual acquaintances?

Joint Bone Spine 2010 Jul 14;77(4):349-50. Epub 2010 May 14.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Tlalpan. 14000 Mexico D.F., Mexico.

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http://dx.doi.org/10.1016/j.jbspin.2010.01.015DOI Listing
July 2010

The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.

Eur J Cancer 2010 Jul 23;46(11):2097-103. Epub 2010 May 23.

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ejca.2010.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900545PMC
July 2010

Vascular endothelial growth factor pathway.

Pharmacogenet Genomics 2010 May;20(5):346-9

Department of Medicine, Section of Hematology/Oncology, University of Chicago, Maryland Avenue, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283364ed7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086058PMC
May 2010

Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy.

Future Oncol 2010 Apr;6(4):563-85

Department of Medicine, The University of Chicago, 5841 S. Maryland Avenue, MC2115, Chicago, IL 60637, USA.

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http://dx.doi.org/10.2217/fon.10.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102300PMC
April 2010

Interactions between MDM2 and TP53 Genetic Alterations, and Their Impact on Response to MDM2 Inhibitors and Other Chemotherapeutic Drugs in Cancer Cells.

Clin Cancer Res 2009 Dec;15(24):7602-7607

Authors' Affiliations: Section of Hematology/Oncology, Department of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, and Cancer Research Center, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794936PMC
December 2009

Lack of association between common polymorphisms in UGT1A9 and gene expression and activity.

Drug Metab Dispos 2007 Dec 30;35(12):2149-53. Epub 2007 Aug 30.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1124/dmd.107.015446DOI Listing
December 2007

Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer.

Cancer Chemother Pharmacol 2007 Nov 17;60(6):811-9. Epub 2007 Feb 17.

Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, 5841 S Maryland Ave, MC2115, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s00280-007-0428-5DOI Listing
November 2007

UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.

Pharmacogenet Genomics 2007 Aug;17(8):619-27

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3280121fe9DOI Listing
August 2007

Effects of green tea compounds on irinotecan metabolism.

Drug Metab Dispos 2007 Feb 15;35(2):228-33. Epub 2006 Nov 15.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1124/dmd.106.012047DOI Listing
February 2007

Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.

Clin Cancer Res 2005 Sep;11(18):6699-704

Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0703DOI Listing
September 2005

A phase I trial of pharmacokinetic modulation of carboxyamidotriazole (CAI) with ketoconazole in patients with advanced cancer.

Cancer Chemother Pharmacol 2004 Nov 3;54(5):377-84. Epub 2004 Jul 3.

Section of Hematology/Oncology, Department of Medicine, University of Chicago, 5841 S Maryland Ave, MC 2115, IL 60637-1470, USA.

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http://link.springer.com/10.1007/s00280-004-0841-y
Publisher Site
http://dx.doi.org/10.1007/s00280-004-0841-yDOI Listing
November 2004

A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.

Clin Pharmacol Ther 2004 Nov;76(5):490-502

Department of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.clpt.2004.07.016DOI Listing
November 2004

CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.

Drug Metab Dispos 2004 Sep;32(9):930-6

University of Chicago, Department of Medicine, Section of Hematology-Oncology, 5841 S. Maryland Avenue, MC2115, Chicago, IL 60637, USA.

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September 2004

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.

Pharmacogenetics 2002 Dec;12(9):725-33

Department of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, Cancer Research Center, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1097/00008571-200212000-00006DOI Listing
December 2002

Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice.

Cancer Chemother Pharmacol 2002 Apr 1;49(4):336-41. Epub 2002 Feb 1.

Department of Medicine, The University of Chicago, 5841 S. Maryland Ave., MC 2115, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s00280-001-0420-4DOI Listing
April 2002