Jacqueline Palace

Jacqueline Palace

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Jacqueline Palace

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Reliable, high-quality suppression of NMR signals arising from water and macromolecules: application to bio-fluid analysis.

Analyst 2019 Dec;144(24):7270-7277

Department of Chemistry. Durham University, South Road, Durham, DH1 3LE, UK.

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http://dx.doi.org/10.1039/c9an01005jDOI Listing
December 2019

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral.

Ann Neurol 2019 Nov 22;86(5):704-713. Epub 2019 Aug 22.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25571DOI Listing
November 2019

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS.

Neurology 2019 Nov 14;93(20):e1852-e1866. Epub 2019 Oct 14.

From the Neuroimaging Research Unit (M.A.R., P.V., A.M., P.P., M.F.) and Neurology Unit (M.A.R., P.P., G.C., M.F.), Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Neurology (C.G., C.Z.), Neurocenter of Southern Switzerland, Regional Hospital Lugano (EOC), Lugano; Faculty of Biomedical Sciences (C.G., C.Z.), Università della Svizzera Italiana, Lugano, Switzerland; Section of Neuroradiology and MRI Unit, Department of Radiology (A.R.), and Department of Neurology/Neuroimmunology (X.M.), Multiple Sclerosis Centre of Catalonia, Hospital Universitari Vall d'Hebron, Barcelona, Spain; NMR Research Unit (H.K., O.C.), Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London; Nuffield Department of Clinical Neurosciences (L.M., J.P.), University of Oxford, UK; Department of Advanced Medical and Surgical Sciences, and 3T MRI Center, (A.G., A.B.), University of Campania "Luigi Vanvitelli," Naples, Italy; Department of Neurology (A.G., P.E.), Universitätsmedizin Mannheim, University of Heidelberg, Germany; Department of Radiology and Nuclear Medicine (C.L., B.B.) and Institute of Neuroradiology (C.L., B.B.), St. Josef Hospital, Ruhr-University Bochum, Germany; Department of Radiology and Nuclear Medicine (F.B., H.V.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, location VUmc, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; and Vita-Salute San Raffaele University (P.P., G.C., M.F.), Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000008466DOI Listing
November 2019

Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling.

Neurol Neuroimmunol Neuroinflamm 2019 Nov 28;6(6):e626. Epub 2019 Oct 28.

From the Department of Pharmacology (T.Y, F.P., M.S., D.C.A.), University of Oxford, UK; Department of Neurology (T.Y.), National Neuroscience Institute, Singapore; Nuffield Department of Clinical Neurosciences (M.J., A.C., M.W., P.W., M.I.L., J.P.), John Radcliffe Hospital, University of Oxford, UK; Department of Chemistry, (T.D.W.C.), Chemistry Research Laboratory, University of Oxford, UK.

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http://dx.doi.org/10.1212/NXI.0000000000000626DOI Listing
November 2019

Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder.

N Engl J Med 2019 11;381(22):2114-2124

From the Department of Immunology, National Institute of Neuroscience, and the Multiple Sclerosis Center, National Center of Neurology and Psychiatry (T.Y.), and Chugai Pharmaceutical (H.Y., Y.K.), Tokyo, and the Department of Multiple Sclerosis Therapeutics, Fukushima Medical University, and the Multiple Sclerosis and Neuromyelitis Optica Center, Southern Tohoku Research Institute for Neuroscience, Koriyama (K.F.) - all in Japan; the Department of Neurology, St. Josef Hospital, Ruhr University Bochum, Bochum, and Marianne-Strauß-Klinik, Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke, Berg - both in Germany (I.K.); the Department of Clinical Neurology, John Radcliffe Hospital, Oxford (J.P.), and Chugai Pharma Europe, London (P.W.) - both in the United Kingdom; the Department of Neurology, University of Texas Southwestern Medical Center, Dallas (B.G.); the Department of Neurology, Warsaw Medical University, Warsaw, Poland (B.Z.-P.); the Department G.F. Ingrassia, Neuroscience Section, University of Catania, Catania, Italy (F.P.); the Neurologic Institute, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan (C.-P.T.); the Service of Neurology, Hospital Clinic and Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Barcelona (A.S.); and the Department of Neurology, Hôpital de Hautepierre, Clinical Investigation Center, INSERM 1434, and Fédération de Médecine Translationelle, INSERM 1119 - all in Strasbourg, France (J.D.S.).

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http://dx.doi.org/10.1056/NEJMoa1901747DOI Listing
November 2019

The frequency of longitudinally extensive transverse myelitis in MS: A population-based study.

Mult Scler Relat Disord 2019 Oct 31;37:101487. Epub 2019 Oct 31.

Departments of Neurology, Mayo Clinic, Rochester, MN, USA; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2019.101487DOI Listing
October 2019

Eculizumab in Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder.

N Engl J Med 2019 08 3;381(7):614-625. Epub 2019 May 3.

From the Mayo Clinic, Rochester, MN (S.J.P.); Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (A.B.); Tohoku University Graduate School of Medicine (K.F., I.N.) and Tohoku Medical and Pharmaceutical University (I.N.), Sendai, School of Medicine, Fukushima Medical University, Fukushima City (K.F.), and Southern Tohoku Research Institute for Neuroscience, Koriyama (K.F.) - all in Japan; Research Institute and Hospital, National Cancer Center, Goyang, South Korea (H.J.K.); Johns Hopkins University, Baltimore (M.L.); Massachusetts General Hospital and Harvard Medical School (M.L.) and Alexion Pharmaceuticals (A.P., K.P.F., R.A.) - all in Boston; John Radcliffe Hospital, Oxford, United Kingdom (J.P.); Ondokuz Mayis University, Samsun, Turkey (M.T.); First Pavlov State Medical University of St. Petersburg, St. Petersburg, Russia (N.T.); Kuala Lumpur Hospital, Kuala Lumpur, Malaysia (S.V.); Cheng-Hsin General Hospital and School of Medicine, National Yang Ming University, Taipei, Taiwan (K.-C.W.); and the Mayo Clinic, Scottsdale, AZ (D.M.W.).

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http://dx.doi.org/10.1056/NEJMoa1900866DOI Listing
August 2019

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease: practical considerations.

Pract Neurol 2019 Jun 8;19(3):187-195. Epub 2018 Dec 8.

Department of Clinical Neurology, John Radcliffe University Hospital, Oxford, UK

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2017-001787
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http://dx.doi.org/10.1136/practneurol-2017-001787DOI Listing
June 2019

A randomised double-blind placebo-controlled feasibility trial of flavonoid-rich cocoa for fatigue in people with relapsing and remitting multiple sclerosis.

J Neurol Neurosurg Psychiatry 2019 May 4;90(5):507-513. Epub 2019 Mar 4.

Department of Sport Health Sciences and Social Work, Centre for Movement Occupational and Rehabilitation Sciences, Oxford Brookes Centre for Nutrition and Health, Oxford Brookes Univeristy, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2018-319496DOI Listing
May 2019

Myasthenia gravis.

Nat Rev Dis Primers 2019 05 2;5(1):30. Epub 2019 May 2.

Department of Neurology, Leiden University Medical Centre, Leiden, Netherlands.

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http://dx.doi.org/10.1038/s41572-019-0079-yDOI Listing
May 2019

Visibility and representation of women in multiple sclerosis research.

Neurology 2019 04 20;92(15):713-719. Epub 2019 Mar 20.

From Blizard Institute (A.T., M.M., G.G.) and Preventive Neurology Unit, Wolfson Institute of Preventive Medicine (C.C., G.G., R.D.), Queen Mary University London; Department of Neurology (M.M., G.G., R.D.), Royal London Hospital, Whitechapel, London; Independent journalist (R.H.), London; and Department of Neurology (J.P.), John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511087PMC
April 2019

Brain and cord imaging features in neuromyelitis optica spectrum disorders.

Ann Neurol 2019 Mar 28;85(3):371-384. Epub 2019 Jan 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://doi.wiley.com/10.1002/ana.25411
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http://dx.doi.org/10.1002/ana.25411DOI Listing
March 2019

Amiloride does not protect retinal nerve fibre layer thickness in optic neuritis in a phase 2 randomised controlled trial.

Mult Scler 2019 02 27;25(2):246-255. Epub 2017 Nov 27.

Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1352458517742979DOI Listing
February 2019

Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge.

Neurology 2019 01 26;92(4):180-192. Epub 2018 Dec 26.

From the Department of Neurosciences (C.G., L.P.), San Camillo-Forlanini Hospital, Rome, Italy; Centre d'Esclerosi Multiple de Catalunya (Cemcat), Department of Neurology/Neuroimmunology (M.T., J.R., J.S.-G., X.M.), and Magnetic Resonance Unit, Department of Radiology (A.R.), Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Spain; Biostatistics Unit (M.P.S.), Department of Health Sciences, University of Genoa; Neuroimaging Research Unit (M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Nuffield Department of Clinical Neurosciences (J.P.), West Wing, John Radcliffe Hospital, Oxford; Institutes of Neurology & Healthcare Engineering (O.C., F.B.), University College London (O.C.), UK; Amsterdam Neuroscience and Department of Radiology and Nuclear Medicine (F.B., H.V.), VU University Medical Center, Amsterdam, the Netherlands; Department of Neurology (J.L.F.), Rigshospitalet Glostrup and University of Copenhagen, Denmark; Neuroradiological Academic Unit (T.A.Y.), Institute of Neurology, London, UK; Department of Neurology (C.E.), Medical University of Graz, Austria; Neurologic Clinic and Policlinic, Department of Medicine (L.K.), Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, University of Basel, Switzerland; Department of Neurology and Psychiatry (C.P.), Sapienza University, Rome; and Neurology and Neurometabolic Unit, Department of Neurological and Behavioral Sciences (N.D.S.), University of Siena, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000006810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345120PMC
January 2019

Multiple sclerosis and the risk of systemic venous thrombosis: A systematic review.

Mult Scler Relat Disord 2019 01 17;27:424-430. Epub 2018 Oct 17.

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals, Oxford, UK.

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http://dx.doi.org/10.1016/j.msard.2018.10.008DOI Listing
January 2019

Retinal ganglion cell loss in neuromyelitis optica: a longitudinal study.

J Neurol Neurosurg Psychiatry 2018 12 19;89(12):1259-1265. Epub 2018 Jun 19.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-318382
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http://dx.doi.org/10.1136/jnnp-2018-318382DOI Listing
December 2018

Racial differences in neuromyelitis optica spectrum disorder.

Neurology 2018 11 26;91(22):e2089-e2099. Epub 2018 Oct 26.

From the Department of Neurology (S.-H.K., H.-J.S., J.-W.H., H.J.K.) and Biometric Research Branch (M.H.), Research Institute and Hospital of National Cancer Center, Goyang, South Korea; Department of Neurology (M.A.M., M.L.), Johns Hopkins University School of Medicine, Baltimore, MD; NeuroCure Clinical Research Center (F.S., F.P.) and Department of Neurology (F.S., K.R., F.P.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Experimental and Clinical Research Center (F.S., F.P.), Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin; Department of Neurology (M.R., O.A., H.-P.H.), Medical Faculty, Heinrich Heine University, Düsseldorf, Germany; Department of Neurology (N.A.), Slagelse Hospital and Institute of Regional Health Research & Molecular Medicine, University of Southern Denmark, Odense; Department of Neurology (J.L.T.-C.), Queen Elizabeth Hospital, Hong Kong, China; Department of Medicine (S.S., N.P.), Siriraj Hospital, Mahidol University, Bangkok, Thailand; and Nuffield Department of Clinical Neurosciences (M.I.L., J.P.), John Radcliffe Hospital, University of Oxford, UK.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282238PMC
November 2018

Area postrema syndrome: Frequency, criteria, and severity in AQP4-IgG-positive NMOSD.

Neurology 2018 10 26;91(17):e1642-e1651. Epub 2018 Sep 26.

From the Departments of Neurology (E.S., D.D., M.M., E.F., A.G., B.W., S.J.P.), Laboratory Medicine and Pathology (M.M., E.F., A.G., S.J.P.), and Clinical Research Unit (C.H., J.S.), Mayo Clinic College of Medicine, Rochester, MN; Nuffield Department of Clinical Neurosciences (J.P., M.I.L., S.M.), Oxford; The Walton Centre (A.J., D.W., L.E.), NHS Foundation Trust, Liverpool, UK; Department of Neurology (I.N., K.F., T.T., T.M., Y.T.), Tohoku University Graduate School of Medicine, Sendai; Department of Multiple Sclerosis Therapeutics (K.F.), Fukushima Medical University School of Medicine and Multiple Sclerosis and Neuromyelitis Optica Center, Southern Tohoku Research Institute for NeuroScience, Koriyama, Japan; Department of Neurology (M.L., A.B.), Johns Hopkins University, Baltimore, MD; Departments of Neurology and Neurotherapeutics (B.M.G.), UT Southwestern Medical Center, Dallas, TX; Department of Neurology (T.T.), Yonezawa National Hospital; and Department of Neurology (I.N.), Tohoku Medical and Pharmaceutical University, Sendai, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000006392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205685PMC
October 2018

Measurement of Whole-Brain and Gray Matter Atrophy in Multiple Sclerosis: Assessment with MR Imaging.

Radiology 2018 08 1;288(2):554-564. Epub 2018 May 1.

From the Neuroimaging Research Unit (L.S., M.A.R., E.P., M.F.) and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience (M.A.R., M.F.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy; Department of Research and Development, Icometrix, Leuven, Belgium (W.V.H., D. Sima, D. Smeets); Xinapse Systems, Colchester, England (M.A.H.); Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy (N.D.S.); Section of Neuroradiology, Department of Radiology, Hospital Universitari Vall d'Hebron, Barcelona, Spain (A.R.); Unit of Clinical Neuroimmunology, CEM-Cat, Hospital Universitari Vall d'Hebron, Barcelona, Spain (J.S.G.); and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England (J.P.).

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http://dx.doi.org/10.1148/radiol.2018172468DOI Listing
August 2018

A practical approach to the diagnosis of spinal cord lesions.

Pract Neurol 2018 Jun 2;18(3):187-200. Epub 2018 Mar 2.

Nuffield Department of Clinical Neuroscience, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/practneurol-2017-001845DOI Listing
June 2018

The Neuromuscular Junction and Wide Heterogeneity of Congenital Myasthenic Syndromes.

Int J Mol Sci 2018 Jun 5;19(6). Epub 2018 Jun 5.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.3390/ijms19061677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032286PMC
June 2018

Time to separate MOG-Ab-associated disease from AQP4-Ab-positive neuromyelitis optica spectrum disorder.

Neurology 2018 05 25;90(21):947-948. Epub 2018 Apr 25.

From the Department of Neuroinflammation (Y.H.), Queen Square MS Centre, UCL Institute of Neurology; Department of Paediatric Neurology (Y.H.), Great Ormond Street Hospital for Children, London; and Neurology Department (J.P.), John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005619DOI Listing
May 2018

Myasthenic syndromes due to defects in COL13A1 and in the N-linked glycosylation pathway.

Ann N Y Acad Sci 2018 02 24;1413(1):163-169. Epub 2018 Jan 24.

Nuffield Department of Clinical Neuroscience, Level 3 The West Wing, The John Radcliffe, Oxford, UK.

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http://doi.wiley.com/10.1111/nyas.13576
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http://dx.doi.org/10.1111/nyas.13576DOI Listing
February 2018

Serological and experimental studies in different forms of myasthenia gravis.

Ann N Y Acad Sci 2018 02 29;1413(1):143-153. Epub 2018 Jan 29.

Neuroimmunology Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/nyas.13592DOI Listing
February 2018

Atypical periodic paralysis and myalgia: A novel phenotype.

Neurology 2018 01 3;90(5):e412-e418. Epub 2018 Jan 3.

From the MRC Centre for Neuromuscular Diseases (E.M., F.J., R.S.S., D.F., M.P., D.R.R., K.S., H.H., E.H., R.Q., J.L.H., M.G.H.), Department of Molecular Neuroscience, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Neuromuscular Diseases Unit/ALS Clinic (C.N.), Kantonsspital St. Gallen, Switzerland; Neurogenetics Unit (R.S., H.H.) and Department of Neuropathology (J.L.H.), National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Human Genetics Laboratory Genetica (R.S.), Zurich, Switzerland; Genetics Department (R.M.), Viapath, Guy's Hospital, London; Wellcome Trust Centre for Mitochondrial Research (A.S.), University of Newcastle, Framlington Place, Newcastle Upon Tyne, UK; Institute of Pathology (E.H.), Belfast Health and Social Care Trust, Northern Ireland; Department of Neurology (J.P.), John Radcliffe Hospital, Oxford, UK; Departments of Biomedicine and Anesthesia (S.T.), Basel University Hospital, Switzerland; Department of Life Sciences (S.T.), Microbiology and Applied Pathology Section, University of Ferrara, Italy; Department of Paediatric Neurology (H.J.), Neuromuscular Service, Evelina Children's Hospital, St. Thomas' Hospital; and Department of Basic and Clinical Neuroscience (H.J.), Institute of Psychiatry, Psychology and Neuroscience, and Randall Division of Cell and Molecular Biophysics (H.J.), Muscle Signalling Section, King's College, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791790PMC
January 2018

Therapeutic strategies for congenital myasthenic syndromes.

Ann N Y Acad Sci 2018 01;1412(1):129-136

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1111/nyas.13538DOI Listing
January 2018

Age-related small vessel disease: a potential contributor to neurodegeneration in multiple sclerosis.

Brain Pathol 2017 11 12;27(6):707-722. Epub 2017 Mar 12.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1111/bpa.12460DOI Listing
November 2017

A mathematical model of cellular swelling in Neuromyelitis optica.

J Theor Biol 2017 11 23;433:39-48. Epub 2017 Aug 23.

Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Old Road Campus Research Building, OX3 7DQ, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2017.08.020DOI Listing
November 2017

Fibrin(ogen) and neurodegeneration in the progressive multiple sclerosis cortex.

Ann Neurol 2017 Aug 19;82(2):259-270. Epub 2017 Aug 19.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ana.24997DOI Listing
August 2017

Differential diagnosis of neuromyelitis optica spectrum disorders.

Ther Adv Neurol Disord 2017 Jul 24;10(7):265-289. Epub 2017 May 24.

Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan Department of Multiple Sclerosis Therapeutics, Fukushima Medical University School of Medicine, and MS & NMO Center, Southern TOHOKU Research Institute for Neuroscience (STRINS), Koriyama 963-8563, Japan.

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http://dx.doi.org/10.1177/1756285617709723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476332PMC
July 2017

Paraneoplastic and idiopathic autoimmune neurologic disorders: approach to diagnosis and treatment.

Handb Clin Neurol 2016 ;133:165-83

Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1016/B978-0-444-63432-0.00010-4DOI Listing
February 2017

Chronic neuropathic pain severity is determined by lesion level in aquaporin 4-antibody-positive myelitis.

J Neurol Neurosurg Psychiatry 2017 Feb 24;88(2):165-169. Epub 2016 Nov 24.

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals NHS Trust, University of Oxford, Oxford, UK.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2016-314991
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http://dx.doi.org/10.1136/jnnp-2016-314991DOI Listing
February 2017

Pain in patients with transverse myelitis and its relationship to aquaporin 4 antibody status.

J Neurol Sci 2016 Sep 23;368:84-8. Epub 2016 Jun 23.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.06.041DOI Listing
September 2016

Clinical features of the myasthenic syndrome arising from mutations in GMPPB.

J Neurol Neurosurg Psychiatry 2016 08 4;87(8):802-9. Epub 2016 May 4.

Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2016-313163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047737PMC
August 2016

Chronic pain disrupts the reward circuitry in multiple sclerosis.

Eur J Neurosci 2016 08 10;44(3):1928-34. Epub 2016 Jun 10.

Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) & Nuffield Division Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/ejn.13272DOI Listing
August 2016

The clinical perspective: How to personalise treatment in MS and how may biomarkers including imaging contribute to this?

Mult Scler 2016 08;22(2 Suppl):18-33

Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1177/1352458516650739DOI Listing
August 2016

Atypical inflammatory demyelinating syndromes of the CNS.

Lancet Neurol 2016 08;15(9):967-981

Department of Neurology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/S1474-4422(16)30043-6DOI Listing
August 2016

International consensus guidance for management of myasthenia gravis: Executive summary.

Neurology 2016 Jul 29;87(4):419-25. Epub 2016 Jun 29.

From the Department of Neurology (D.B.S., J.M.M.), Duke University Medical Center, Durham, NC; Department of Neurology (G.I.W.), University at Buffalo School of Medicine and Biomedical Sciences, State University of New York; Department of Neurology (M.B.), University of Miami, Miller School of Medicine, FL; Department of Neurology (A.E.), Catholic University, Rome, Italy; Department of Clinical Medicine (N.E.G.), University of Bergen, Norway; Department of Neurology (I.I.), Hospital Santa Creu i Sant Pau, Universitat Autònoma de Barcelona; CIBERER U762 (I.I.), Barcelona, Spain; Departments of Pediatrics and Neurology (N.K.), Northwestern Feinberg School of Medicine, Chicago, IL; Neurologische Klinik (A.M.), Universitätsklinikum Erlangen; Hertie Institute for Clinical Research (A.M.), University of Tübingen, Germany; Department of Neurological Therapeutics (H.M.), Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Clinical Neurological Sciences (M.N.), Western University, London, Canada; Department of Clinical Neurology (J.P.), John Radcliffe Hospital, Oxford University Hospitals Trust, Oxford, UK; Department of Neurology (D.P.R.), University of California, Davis, CA; Department of Neurology (J.V.), Leiden University Medical Centre, Leiden, the Netherlands; and Department of Neurology, Beth Israel Deaconess Medical Center/Harvard Medical School (P.N.), Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977114PMC
July 2016

Imaging Surrogates of Disease Activity in Neuromyelitis Optica Allow Distinction from Multiple Sclerosis.

PLoS One 2015 18;10(9):e0137715. Epub 2015 Sep 18.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; Neurology Department, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575169PMC
May 2016

Neuromyelitis optica relapses: Race and rate, immunosuppression and impairment.

Mult Scler Relat Disord 2016 May 16;7:21-5. Epub 2016 Feb 16.

Nuffield Department of Clinical Neurosciences, Oxford University, John Radcliffe Hospital, Oxford, UK. Electronic address:

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May 2016

Myasthenia gravis: a clinical-immunological update.

J Neurol 2016 Apr 24;263(4):826-34. Epub 2015 Dec 24.

Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826656PMC
April 2016

The UK Risk-Sharing Scheme for interferon-beta and glatiramer acetate in multiple sclerosis. Outcome of the year-6 analysis.

Pract Neurol 2016 Feb 1;16(1):4-6. Epub 2015 Oct 1.

Department of Clinical Neurology, Oxford University Hospitals Trust, Oxford, UK.

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February 2016

Salbutamol-responsive fetal acetylcholine receptor inactivation syndrome.

Neurology 2016 Feb 20;86(7):692-4. Epub 2016 Jan 20.

From Evelina's Children Hospital (N.M.A., H.J.), Guy's & St. Thomas' Hospital NHS Foundation Trust, London; University of Oxford (Y.H., D.B., A.V.); John Radcliffe Hospital (J.P.), Oxford; and King's College (H.J.), London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762416PMC
February 2016

Multiple sclerosis in Japan appears to be a milder disease compared to the UK.

J Neurol 2015 22;262(4):831-6. Epub 2015 Jan 22.

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals NHS Trust, University of Oxford, Level 3 West Wing, Headley Way, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1007/s00415-015-7637-3DOI Listing
January 2016

Pregnancy outcomes in aquaporin-4-positive neuromyelitis optica spectrum disorder.

Neurology 2016 Jan 18;86(1):79-87. Epub 2015 Nov 18.

From the Nuffield Department of Clinical Neurosciences (M.M.N., E.C., M.W., J.R., J.G., J.K., J.M.N., F.C., G.C.D., A.V., J.P., P.W., M.I.L.), John Radcliffe Hospital, University of Oxford, UK; Departments of Neurology (I.N., Y.T., H.K.) and Multiple Sclerosis Therapeutics (T.M., K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Clinical Neurology (F.S.), Hospital de São Marcos, Braga; and Department of Clinical Neurology (A.M.-d.-S., M.E.S.), Hospital Geral Santo Antonio, Porto, Portugal.

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http://dx.doi.org/10.1212/WNL.0000000000002208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731292PMC
January 2016

Antibodies to aquaporin-1 are not present in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Dec 1;2(6):e160. Epub 2015 Oct 1.

Clinical Department of Neurology (K.S., H.H., T.B., M.R.), Medical University of Innsbruck, Austria; Nuffield Department of Clinical Neurosciences (P.W., M.I.L.), University of Oxford, United Kingdom; Department of Neurology (F.A.-D.), Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders, Sozialmedizinisches Zentrum Ost Donauspital, Vienna, Austria; Department of Neurology (J.P.), Oxford University Hospitals Trust, Oxford, United Kingdom; and Department of Neurology (S.V., R.M.), Lyon University Hospital and Lyon Neurosciences Research Centre, Lyon, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592537PMC
December 2015

Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol: a randomised, double blind, placebo controlled trial.

BMJ Open 2015 Nov 9;5(11):e009200. Epub 2015 Nov 9.

Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1136/bmjopen-2015-009200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654308PMC
November 2015

Structural imaging of the cervical spinal cord with suppressed CSF signal using DANTE pulse trains.

Magn Reson Med 2015 Oct 25;74(4):971-7. Epub 2014 Sep 25.

FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/mrm.25474DOI Listing
October 2015

Predictive value of MRI parameters in severity and recovery of first-episode myelitis in aquaporin-4 antibody disease.

J Neurol Sci 2015 Aug 16;355(1-2):49-53. Epub 2015 May 16.

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals NHS Trust, University of Oxford, Oxford, UK. Electronic address:

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August 2015

Update on biomarkers in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 23;2(4):e134. Epub 2015 Jul 23.

Stanford University (E.M., M.H.H.), Stanford, CA; Johns Hopkins University (M.L.), Baltimore, MD; University of Oxford (P.J.W.), UK; Tohoku University (D.K.S.), Sendai, Japan; University of São Paulo (D.K.S.), Brazil; University of Colorado (J.L.B.), Denver; Mt. Sinai University (G.R.J.), New York, NY; Thomas Jefferson University (D.C.H.), Philadelphia, PA; IDIBAPS (A.S.), Barcelona, Spain; Montreal Neurological Institute and Hospital (A.B.-O.), McGill University, Montreal, Quebec, Canada; Research Institute and Hospital of National Cancer Center (H.J.K.), Goyang, Korea; KS Hegde Medical Academy (L.P.), Nitte University, Mangalore, India; Oxford University Hospital (M.I.L.), Oxford, UK; University of Southern Denmark (N.A.), Odense; Vejle Hospital (N.A.), Denmark; University Hospital (N.K.), Marrakech, Morocco; MS Center (R.H.), Erasmus MC University Medical Center, Rotterdam, the Netherlands; Service de Neurologie A (R.M.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France; Molecular Neuroimmunology (S.J.), Department of Neurology, University Hospital Heidelberg, Germany; Tandem Labs (J.M.), San Diego, CA; University of Michigan Medical School (T.J.S.), Ann Arbor, MI; and David Geffen School of Medicine (M.R.Y.), University of California, Los Angeles.

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http://dx.doi.org/10.1212/NXI.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516398PMC
August 2015

MOG cell-based assay detects non-MS patients with inflammatory neurologic disease.

Neurol Neuroimmunol Neuroinflamm 2015 Jun 19;2(3):e89. Epub 2015 Mar 19.

Nuffield Department of Clinical Neurosciences (P.W., M.W., B.L., M.J., G.T., J.R., J.P., M.I.L., A.V.), John Radcliffe Hospital, Oxford, UK; Department of Neurology (K.C.O.), Yale School of Medicine, New Haven, CT; Clinical Department of Neurology (M.R.), Innsbruck Medical University, Innsbruck, Austria; Department of Neurology (D.K.S., I.N.) and Department of Multiple Sclerosis Therapeutics (T.M., K.F.) Tohoku University School of Medicine, Sendai, Japan; and Department of Neurology (T.T.), Yonezawa National Hospital, Yonezawa, Japan.

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http://dx.doi.org/10.1212/NXI.0000000000000089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370386PMC
June 2015

Placebo studies should not be undertaken in NMO--Yes.

Mult Scler 2015 May 28;21(6):689-91. Epub 2015 Apr 28.

Neurology Department, University of Oxford and Oxford Radcliffe Hospitals NHS Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK

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http://dx.doi.org/10.1177/1352458515579446DOI Listing
May 2015

The influence of HLA-DRB1*15 on motor cortical pathology in multiple sclerosis.

Neuropathol Appl Neurobiol 2015 Apr;41(3):371-84

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/nan.12165DOI Listing
April 2015

Paediatric neuromyelitis optica: clinical, MRI of the brain and prognostic features.

J Neurol Neurosurg Psychiatry 2015 Apr 4;86(4):470-2. Epub 2014 Aug 4.

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals National Health Service Trust, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2014-308550DOI Listing
April 2015

Myelin oligodendrocyte glycoprotein antibodies are associated with a non-MS course in children.

Neurol Neuroimmunol Neuroinflamm 2015 Apr 12;2(2):e81. Epub 2015 Mar 12.

Nuffield Department of Clinical Neurosciences (Y.H., M.W., J.P., A.V., M.L., P.W.), John Radcliffe Hospital, University of Oxford, UK; Children's Neurosciences (M.A., M.L.), Evelina Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, King's Health Partners Academic Health Science Centre, London, UK; Assistance Publique Hôpitaux de Paris (K.D., M.T.), Hopitaux Universitaires Paris Sud, France; Pediatric Neurology Department and National Referral Center for Neuroinflammatory Diseases (K.D., M.T.), Université Paris Sud, Le Kremlin-Bicêtre, Paris, France; Department of Paediatric Neurology (C.H.), Great Ormond Street Hospital for Children, London, UK; Department of Neurology and Center of Clinical Neuroscience (P.N.), General University Hospital in Prague, Czech Republic; First Faculty of Medicine (P.N.), Charles University in Prague, Czech Republic; and Department of Paediatric Neurology (E.W.), Birmingham Children's Hospital, UK.

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http://dx.doi.org/10.1212/NXI.0000000000000081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360800PMC
April 2015

Challenges and opportunities in designing clinical trials for neuromyelitis optica.

Neurology 2015 Apr 3;84(17):1805-15. Epub 2015 Apr 3.

From the Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN; MedImmune Ltd. (G.B., A.F.), Riverside Building, Granta Park, Great Abington, Cambridge, UK; Guthy-Jackson Foundation (J.M.B., K.V.H.), San Diego, CA; Departments of Neurology and Ophthalmology (J.L.B.), University of Colorado Denver, Aurora; Novartis Pharmaceuticals Corporation (P.S.C.), East Hanover, NJ; Department of Neurology (B.A.C.C.), University of California San Francisco; CIC (Clinical Investigation Center) INSERM and UMR 1119 (J.d.S.), INSERM, Federation de Medecine Translationelle de Strasbourg, Université de Strasbourg; Department of Multiple Sclerosis Therapeutics (K.F.), Tohoku University, Sendai, Japan; Department of Neurology (B.G.), University of Texas Southwestern; Chugai Pharma USA (S.H., A.T.M.), Berkeley Heights, NJ; PPD Inc. (W.H.), Wilmington, NC; Department of Neurology (O.K.), Wayne State University, Detroit, MI; Teva Pharmaceuticals (V.K.), Frazer, PA; Department of Neurology (V.K.), Heinrich-Heine University, Dusseldorf, Germany; Department of Neurology (M.L.), Johns Hopkins University, Baltimore, MD; Department of Neurology (J.P.), Oxford University Hospital Trust, UK; Department of Ophthalmology and Visual Sciences (T.J.S.), Kellogg Eye Center, and Division of Metabolism, Endocrine, and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor; Department of Health Science (M.P.S.), University of Genoa, Italy; David Geffen School of Medicine at UCLA (K.V.H.), Los Angeles, CA; GlaxoSmithKline (S.V.), Research Triangle Park, NC; Center of Neuroimmunology (P.V.), Institute of Biomedical Research August Pi Sunyer (IDIBAPS)-Hospital Clinic Barcelona, Villarroel, Spain; United States Food and Drug Administration (M.K.W.), Center for Drug Evaluation and Research, Silver Spring, MD; Alexion Pharmaceuticals Inc. (W.W.), Cheshire, CT; Department of Neurology (D.M.W.), Mayo Clinic, Scottsdale, AZ; Department of Medicine (M.R.Y.), Divisions of M

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000152
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http://dx.doi.org/10.1212/WNL.0000000000001520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424131PMC
April 2015

MRI characteristics of neuromyelitis optica spectrum disorder: an international update.

Neurology 2015 Mar 18;84(11):1165-73. Epub 2015 Feb 18.

From the Department of Neurology (H.J.K., S.-H.K.), Research Institute and Hospital of National Cancer Center, Goyang, Korea; NeuroCure Clinical Research Center and Clinical and Experimental Multiple Sclerosis Research Center (F.P., J.W.), Department of Neurology, Charité University Medicine, Berlin, Germany; CIEM MS Research Center (M.A.L.-P.), Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil; Department of Neurology (S.T.), National Paediatric Hospital Dr. Juan P. Garrahan, Buenos Aires, Argentina; Neurobiology (N.A.), Institute of Molecular Medicine, University of Southern Denmark; Department of Neurology (N.A.), Vejle Hospital, Denmark; Department of Clinical Neurology (J.P.), John Radcliffe Hospital, Oxford, UK; Department of Neurology, Massachusetts General Hospital (E.C.K.), Harvard Medical School, Boston, MA; Department of Neurology (D.K.S.), Tohoku University School of Medicine, Sendai, Japan; Neurology Department (J.d.S.), Hôpitaux Universitaires de Strasbourg, France; Institute of Neuroradiology (J.W.), University Medicine Goettingen, Germany; Department of Pediatrics (B.L.B.), Division of Neurology, The Children's Hospital of Philadelphia; Department of Neurology (B.L.B.), The University of Pennsylvania; Center of Neuroimmunology (P.V., A.S.), Service of Neurology, Hospital Clinic and Institute of Biomedical Research August Pi Sunyer, Barcelona, Spain; and Department of Multiple Sclerosis Therapeutics (K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371410PMC
March 2015

Overlapping CNS inflammatory diseases: differentiating features of NMO and MS.

J Neurol Neurosurg Psychiatry 2015 Jan 23;86(1):20-5. Epub 2014 Sep 23.

Department of Neurology, Oxford University Hospitals National Health Service Trust, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2014-308984DOI Listing
January 2015

Congenital myopathies with secondary neuromuscular transmission defects; a case report and review of the literature.

Neuromuscul Disord 2014 Dec 30;24(12):1103-10. Epub 2014 Jul 30.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2014.07.005DOI Listing
December 2014

Neuroimmunology: towards more-accurate diagnosis in neuromyelitis optica.

Nat Rev Neurol 2014 Dec 11;10(12):679-81. Epub 2014 Nov 11.

Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1038/nrneurol.2014.216DOI Listing
December 2014

Inherited disorders of the neuromuscular junction: an update.

J Neurol 2014 Nov 11;261(11):2234-43. Epub 2014 Oct 11.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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November 2014

Congenital myasthenic syndromes and the neuromuscular junction.

Curr Opin Neurol 2014 Oct;27(5):566-75

aNuffield Department of Clinical Neurosciences, University of Oxford bNeurosciences Group, Weatherall Institute of Molecular Medicine, University of Oxford, The John Radcliffe Hospital, Oxford, UK.

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October 2014

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis.

Neurology 2014 Oct 24;83(17):1492-9. Epub 2014 Sep 24.

From the CR-UK/MRC Gray Institute for Radiation Oncology and Biology (A.M.D., J.R.L., N.R.S.), Department of Pharmacology (A.M.D., D.C.A.), Department of Chemistry (A.M.D., B.G.D., T.D.W.C.), Nuffield Department of Clinical Neurosciences (A.C., L.M., M.R.T.), and Nuffield Department of Medicine (G.K.W.), University of Oxford; and the Department of Biochemistry (J.L.G., J.P.), University of Cambridge, UK.

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http://dx.doi.org/10.1212/WNL.0000000000000905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222850PMC
October 2014

Magnetic resonance imaging in neuromyelitis optica.

Mult Scler 2014 08 14;20(9):1153-64. Epub 2014 May 14.

Oxford University Hospitals Trust, Oxford, OX3 9DU, UK

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http://dx.doi.org/10.1177/1352458514531087DOI Listing
August 2014

Features of neuromyelitis optica spectrum disorders and aquaporin-4 with myelin-oligodendrocyte glycoprotein antibodies-reply.

JAMA Neurol 2014 Jul;71(7):924

Nuffield Department of Clinical Neurosciences, Oxford University Hospitals NHS Trust, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamaneurol.2014.940DOI Listing
July 2014

The role of imaging in diagnosing neuromyelitis optica spectrum disorder.

Mult Scler Relat Disord 2014 May 4;3(3):284-93. Epub 2013 Dec 4.

Oxford University Hospitals NHS Trust, United Kingdom; Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.msard.2013.11.003DOI Listing
May 2014