Publications by authors named "Jacqueline K Barton"

100Publications

Extracellular DNA Promotes Efficient Extracellular Electron Transfer by Pyocyanin in Pseudomonas aeruginosa Biofilms.

Cell 2020 Aug 6;182(4):919-932.e19. Epub 2020 Aug 6.

Division of Biology and Biological Engineering, Caltech, Pasadena, CA, USA; Division of Geological and Planetary Sciences, Caltech, Pasadena, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457544PMC
August 2020

In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model.

Proc Natl Acad Sci U S A 2020 07 13;117(30):17535-17542. Epub 2020 Jul 13.

Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125;

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http://dx.doi.org/10.1073/pnas.2006569117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395490PMC
July 2020

UvrC Coordinates an O-Sensitive [4Fe4S] Cofactor.

J Am Chem Soc 2020 Jun 12;142(25):10964-10977. Epub 2020 Jun 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.0c01671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392197PMC
June 2020

Cell-Selective Cytotoxicity of a Fluorescent Rhodium Metalloinsertor Conjugate Results from Irreversible DNA Damage at Base Pair Mismatches.

Biochemistry 2020 02 30;59(5):717-726. Epub 2020 Jan 30.

Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b01037DOI Listing
February 2020

Redox Chemistry in the Genome: Emergence of the [4Fe4S] Cofactor in Repair and Replication.

Annu Rev Biochem 2019 06;88:163-190

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA; email:

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http://dx.doi.org/10.1146/annurev-biochem-013118-110644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590699PMC
June 2019

Effective Distance for DNA-Mediated Charge Transport between Repair Proteins.

ACS Cent Sci 2019 Jan 11;5(1):65-72. Epub 2019 Jan 11.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acscentsci.8b00566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346725PMC
January 2019

Cellular Target of a Rhodium Metalloinsertor is the DNA Base Pair Mismatch.

Chemistry 2019 Feb 29;25(12):3014-3019. Epub 2019 Jan 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 127-72, Pasadena, California, 91125, USA.

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http://dx.doi.org/10.1002/chem.201900042DOI Listing
February 2019

Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.

PLoS One 2018 18;13(12):e0209345. Epub 2018 Dec 18.

Departments of Biochemistry and Chemistry, and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209345PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298731PMC
May 2019

Yeast require redox switching in DNA primase.

Proc Natl Acad Sci U S A 2018 12 12;115(52):13186-13191. Epub 2018 Dec 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125;

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http://dx.doi.org/10.1073/pnas.1810715115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310810PMC
December 2018

Substrate Binding Regulates Redox Signaling in Human DNA Primase.

J Am Chem Soc 2018 12 29;140(49):17153-17162. Epub 2018 Nov 29.

Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

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http://pubs.acs.org/doi/10.1021/jacs.8b09914
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http://dx.doi.org/10.1021/jacs.8b09914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470046PMC
December 2018

Sensing DNA through DNA Charge Transport.

ACS Chem Biol 2018 07 1;13(7):1799-1809. Epub 2018 Jun 1.

Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

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http://dx.doi.org/10.1021/acschembio.8b00347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080280PMC
July 2018

A Compass at Weak Magnetic Fields Using Thymine Dimer Repair.

ACS Cent Sci 2018 Mar 7;4(3):405-412. Epub 2018 Mar 7.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acscentsci.8b00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879481PMC
March 2018

A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers.

J Am Chem Soc 2018 04 17;140(16):5612-5624. Epub 2018 Apr 17.

Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

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http://dx.doi.org/10.1021/jacs.8b02271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965675PMC
April 2018

A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ.

J Am Chem Soc 2017 12 6;139(50):18339-18348. Epub 2017 Dec 6.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.7b10284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881389PMC
December 2017

A Rhodium-Cyanine Fluorescent Probe: Detection and Signaling of Mismatches in DNA.

J Am Chem Soc 2017 12 21;139(48):17301-17304. Epub 2017 Nov 21.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.7b10639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892186PMC
December 2017

The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins.

J Am Chem Soc 2017 09 29;139(36):12784-12792. Epub 2017 Aug 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.7b07230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929122PMC
September 2017

Sulfur K-Edge XAS Studies of the Effect of DNA Binding on the [FeS] Site in EndoIII and MutY.

J Am Chem Soc 2017 08 10;139(33):11434-11442. Epub 2017 Aug 10.

Department of Chemistry, Stanford University , Stanford, California 94035, United States.

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http://dx.doi.org/10.1021/jacs.7b03966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568943PMC
August 2017

A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites.

Inorg Chem 2017 Jul 28;56(14):8381-8389. Epub 2017 Jun 28.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acs.inorgchem.7b01037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516787PMC
July 2017

Electrical Probes of DNA-Binding Proteins.

Methods Enzymol 2017 10;591:355-414. Epub 2017 May 10.

California Institute of Technology, Pasadena, CA, United States.

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http://dx.doi.org/10.1016/bs.mie.2017.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314295PMC
April 2018

Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.

Proc Natl Acad Sci U S A 2017 07 20;114(27):6948-6953. Epub 2017 Jun 20.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125

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http://dx.doi.org/10.1073/pnas.1706665114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502648PMC
July 2017

The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.

Science 2017 02;355(6327)

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1126/science.aag1789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338353PMC
February 2017

Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA.

Langmuir 2017 03 2;33(10):2523-2530. Epub 2017 Mar 2.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acs.langmuir.6b04581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423460PMC
March 2017

Redox Signaling through DNA.

Isr J Chem 2016 Oct 29;56(9-10):705-723. Epub 2016 Jul 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena CA 91125.

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http://dx.doi.org/10.1002/ijch.201600022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225960PMC
October 2016

Helix-Dependent Spin Filtering through the DNA Duplex.

J Am Chem Soc 2016 12 22;138(48):15551-15554. Epub 2016 Nov 22.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.6b10538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175457PMC
December 2016

Targeting DNA Mismatches with Rhodium Metalloinsertors.

Inorganica Chim Acta 2016 Oct 16;452:3-11. Epub 2016 Jan 16.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena CA 91125.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061454PMC
http://dx.doi.org/10.1016/j.ica.2016.01.021DOI Listing
October 2016

Characterization of the DNA-Mediated Oxidation of Dps, A Bacterial Ferritin.

J Am Chem Soc 2016 09 29;138(35):11290-8. Epub 2016 Aug 29.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.6b06507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014645PMC
September 2016

[Ru(Me4phen)2dppz](2+), a Light Switch for DNA Mismatches.

J Am Chem Soc 2016 Apr 12;138(15):5020-3. Epub 2016 Apr 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/jacs.6b02022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989906PMC
April 2016

DNA Charge Transport: from Chemical Principles to the Cell.

Cell Chem Biol 2016 Jan;23(1):183-197

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803044PMC
January 2016

A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.

Inorg Chem 2015 Oct 23;54(19):9626-36. Epub 2015 Sep 23.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acs.inorgchem.5b01722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618505PMC
October 2015

DNA Electrochemistry Shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors.

Chem Biol 2015 Jul 25;22(7):938-45. Epub 2015 Jun 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518711PMC
July 2015

A Multiplexed, Two-Electrode Platform for Biosensing Based on DNA-Mediated Charge Transport.

Langmuir 2015 Jun 4;31(23):6554-62. Epub 2015 Jun 4.

†Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/acs.langmuir.5b00829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587567PMC
June 2015

Targeted Chemotherapy with Metal Complexes.

Comments Mod Chem A Comments Inorg Chem 2014 May;34(3-4):114-123

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.

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http://dx.doi.org/10.1080/02603594.2014.890099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309285PMC
May 2014

DNA charge transport within the cell.

Biochemistry 2015 Feb 21;54(4):962-73. Epub 2015 Jan 21.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/bi501520wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587570PMC
February 2015

Oxidation of p53 through DNA charge transport involves a network of disulfides within the DNA-binding domain.

Biochemistry 2015 Jan 13;54(3):932-41. Epub 2015 Jan 13.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/bi501424vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310631PMC
January 2015

Electrocatalysis in DNA Sensors.

Polyhedron 2014 Dec;84:150-159

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena CA 91125.

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http://dx.doi.org/10.1016/j.poly.2014.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243183PMC
December 2014

Label-free electrochemical detection of human methyltransferase from tumors.

Proc Natl Acad Sci U S A 2014 Oct 6;111(42):14985-9. Epub 2014 Oct 6.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125; and

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http://www.pnas.org/lookup/doi/10.1073/pnas.1417351111
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http://dx.doi.org/10.1073/pnas.1417351111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210341PMC
October 2014

An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.

J Am Chem Soc 2014 Oct 25;136(40):14160-72. Epub 2014 Sep 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena California 91125, United States.

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http://dx.doi.org/10.1021/ja5072064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195389PMC
October 2014

Construction and application of a Rh-Pt DNA metalloinsertor conjugate.

Inorg Chem 2014 Aug 17;53(15):7812-4. Epub 2014 Jul 17.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ic501509xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123934PMC
August 2014

DNA-mediated oxidation of p53.

Biochemistry 2014 Jun 22;53(21):3467-75. Epub 2014 May 22.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/bi5003184DOI Listing
June 2014

DNA-mediated signaling by proteins with 4Fe-4S clusters is necessary for genomic integrity.

J Am Chem Soc 2014 Apr 16;136(17):6470-8. Epub 2014 Apr 16.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja501973cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017601PMC
April 2014

DNA-modified electrodes fabricated using copper-free click chemistry for enhanced protein detection.

Langmuir 2013 Dec 11;29(52):16141-9. Epub 2013 Dec 11.

Department of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/la403262vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947573PMC
December 2013

Electrochemical patterning and detection of DNA arrays on a two-electrode platform.

J Am Chem Soc 2013 Dec 12;135(51):19099-102. Epub 2013 Dec 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja410902jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026266PMC
December 2013

DNA protection by the bacterial ferritin Dps via DNA charge transport.

J Am Chem Soc 2013 Oct 11;135(42):15726-9. Epub 2013 Oct 11.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja408760wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899832PMC
October 2013

Intraduplex DNA-mediated electrochemistry of covalently tethered redox-active reporters.

J Am Chem Soc 2013 Oct 30;135(40):14944-7. Epub 2013 Sep 30.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja408135gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899830PMC
October 2013

Luminescence of [Ru(bpy)2(dppz)]2+ bound to RNA mismatches.

Inorg Chem 2013 Sep 22;52(17):10131-6. Epub 2013 Aug 22.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ic401531rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823503PMC
September 2013

Multiplexed electrochemistry of DNA-bound metalloproteins.

J Am Chem Soc 2013 Aug 30;135(32):11869-78. Epub 2013 Jul 30.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja4041779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899834PMC
August 2013

Biological effects of simple changes in functionality on rhodium metalloinsertors.

Philos Trans A Math Phys Eng Sci 2013 Jul 17;371(1995):20120117. Epub 2013 Jun 17.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1098/rsta.2012.0117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685451PMC
July 2013

The path for metal complexes to a DNA target.

Chem Commun (Camb) 2013 May;49(35):3617-30

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1039/c3cc00177fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660861PMC
May 2013

Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization.

J Am Chem Soc 2012 Nov 8;134(46):19223-33. Epub 2012 Nov 8.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja3090687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740518PMC
November 2012

Luminescent properties of ruthenium(II) complexes with sterically expansive ligands bound to DNA defects.

Inorg Chem 2012 Nov 31;51(22):12511-20. Epub 2012 Oct 31.

Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ic3019524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622160PMC
November 2012

DNA charge transport for sensing and signaling.

Acc Chem Res 2012 Oct 3;45(10):1792-800. Epub 2012 Aug 3.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, 91125, United States.

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http://dx.doi.org/10.1021/ar3001298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495616PMC
October 2012

Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport.

Phys Chem Chem Phys 2012 Oct 31;14(40):13754-71. Epub 2012 Jul 31.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://xlink.rsc.org/?DOI=c2cp41602f
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http://dx.doi.org/10.1039/c2cp41602fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478128PMC
October 2012

Crystal structure of Δ-[Ru(bpy)₂dppz]²⁺ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation.

Nat Chem 2012 Jun 10;4(8):615-20. Epub 2012 Jun 10.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1038/nchem.1375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478149PMC
June 2012

Transducing methyltransferase activity into electrical signals in a carbon nanotube-DNA device().

Chem Sci 2012 Jan 20;3(1):62-65. Epub 2011 Oct 20.

Department of Chemistry, Columbia University, New York, NY, 10027, USA;

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http://dx.doi.org/10.1039/C1SC00772FDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399246PMC
January 2012

DNA sensing by electrocatalysis with hemoglobin.

Proc Natl Acad Sci U S A 2012 Jul 25;109(29):11528-33. Epub 2012 Jun 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1201551109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406877PMC
July 2012

DNA electrochemistry with tethered methylene blue.

Langmuir 2012 May 18;28(17):7063-70. Epub 2012 Apr 18.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/la300566xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398613PMC
May 2012

DNA charge transport as a first step in coordinating the detection of lesions by repair proteins.

Proc Natl Acad Sci U S A 2012 Feb 23;109(6):1856-61. Epub 2012 Jan 23.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1120063109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277573PMC
February 2012

Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.

Biochemistry 2011 Dec 21;50(50):10919-28. Epub 2011 Nov 21.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/bi2015822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364161PMC
December 2011

Using metal complex reduced states to monitor the oxidation of DNA.

Inorg Chem 2011 Dec 1;50(23):12034-44. Epub 2011 Nov 1.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ic201511yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277451PMC
December 2011

ATP-stimulated, DNA-mediated redox signaling by XPD, a DNA repair and transcription helicase.

J Am Chem Soc 2011 Oct 22;133(41):16378-81. Epub 2011 Sep 22.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja207222tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234108PMC
October 2011

Charge photoinjection in intercalated and covalently bound [Re(CO)3(dppz)(py)]+-DNA constructs monitored by time-resolved visible and infrared spectroscopy.

J Am Chem Soc 2011 Aug 9;133(34):13718-30. Epub 2011 Aug 9.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja205568rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227519PMC
August 2011

Mutants of the base excision repair glycosylase, endonuclease III: DNA charge transport as a first step in lesion detection.

Biochemistry 2011 Jul 9;50(27):6133-45. Epub 2011 Jun 9.

Division of Chemistry and Chemical Engineering, California Institute of Technolog, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi2003179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134277PMC
July 2011

Metal Complexes for DNA-Mediated Charge Transport.

Coord Chem Rev 2011 Apr;255(7-8):619-634

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1016/j.ccr.2010.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105778PMC
April 2011

Single-step charge transport through DNA over long distances.

J Am Chem Soc 2011 Mar 24;133(11):3863-8. Epub 2011 Feb 24.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

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http://dx.doi.org/10.1021/ja107033vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079569PMC
March 2011

DNA charge transport over 34 nm.

Nat Chem 2011 Mar 30;3(3):228-33. Epub 2011 Jan 30.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1038/nchem.982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079570PMC
March 2011

Targeting a ruthenium complex to the nucleus with short peptides.

Bioorg Med Chem 2010 May 8;18(10):3564-9. Epub 2010 Apr 8.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, United States.

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http://dx.doi.org/10.1016/j.bmc.2010.03.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873839PMC
May 2010

DNA-mediated electron transfer in naphthalene-modified oligonucleotides.

J Org Chem 2010 Apr;75(8):2423-8

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/jo1000862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879047PMC
April 2010

Mechanisms for DNA charge transport.

Chem Rev 2010 Mar;110(3):1642-62

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/cr900228fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879062PMC
March 2010

Multiplexed DNA-modified electrodes.

J Am Chem Soc 2010 Mar;132(8):2769-74

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja909915mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334307PMC
March 2010

Exploring the cellular accumulation of metal complexes.

Dalton Trans 2010 Feb 23;39(5):1159-70. Epub 2009 Dec 23.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1039/b922209jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873847PMC
February 2010

DNA-mediated charge transport in redox sensing and signaling.

J Am Chem Soc 2010 Jan;132(3):891-905

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja907669cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902267PMC
January 2010

Redox signaling between DNA repair proteins for efficient lesion detection.

Proc Natl Acad Sci U S A 2009 Sep 31;106(36):15237-42. Epub 2009 Aug 31.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0908059106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741234PMC
September 2009

DNA-mediated redox signaling for transcriptional activation of SoxR.

Proc Natl Acad Sci U S A 2009 Aug 27;106(32):13164-8. Epub 2009 Jul 27.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0906429106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726364PMC
August 2009

Fluorescein redirects a ruthenium-octaarginine conjugate to the nucleus.

J Am Chem Soc 2009 Jul;131(25):8738-9

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja9025165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747598PMC
July 2009

Sensitivity of Ru(bpy)2dppz2+ luminescence to DNA defects.

Inorg Chem 2009 Jun;48(12):5392-7

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ic900407nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747521PMC
June 2009

Molecular electronics: DNA charges ahead.

Nat Chem 2009 May;1(2):106-7

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http://dx.doi.org/10.1038/nchem.188DOI Listing
May 2009

A bulky rhodium complex bound to an adenosine-adenosine DNA mismatch: general architecture of the metalloinsertion binding mode.

Biochemistry 2009 May;48(20):4247-53

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi900194eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747516PMC
May 2009

DNA mismatch binding and antiproliferative activity of rhodium metalloinsertors.

J Am Chem Soc 2009 Feb;131(6):2359-66

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja8081044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747594PMC
February 2009

Recognition of abasic sites and single base bulges in DNA by a metalloinsertor.

Biochemistry 2009 Feb;48(5):839-49

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi801885wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747346PMC
February 2009

Common mitochondrial DNA mutations generated through DNA-mediated charge transport.

Biochemistry 2009 Feb;48(4):660-6

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi801570jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668510PMC
February 2009

Scanning electrochemical microscopy of DNA monolayers modified with Nile Blue.

Langmuir 2008 Dec;24(24):14282-8

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/la8029243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668266PMC
December 2008

DNA-mediated electrochemistry.

Bioconjug Chem 2008 Dec;19(12):2285-96

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bc8003149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663395PMC
December 2008

Ping-pong electron transfer through DNA.

Angew Chem Int Ed Engl 2008 ;47(47):9067-70

Chimie Organique et Médicinale, Université catholique de Louvain, Belgium.

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http://dx.doi.org/10.1002/anie.200803556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748353PMC
December 2008

Mechanism of cellular uptake of a ruthenium polypyridyl complex.

Biochemistry 2008 Nov 15;47(45):11711-6. Epub 2008 Oct 15.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi800856tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747514PMC
November 2008

Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts.

J Am Chem Soc 2008 Nov 15;130(45):15150-6. Epub 2008 Oct 15.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja8052738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663386PMC
November 2008

Redmond Red as a redox probe for the DNA-mediated detection of abasic sites.

Bioconjug Chem 2008 Nov;19(11):2110-2

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bc800339yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747513PMC
November 2008

Conductivity of a single DNA duplex bridging a carbon nanotube gap.

Nat Nanotechnol 2008 Mar 10;3(3):163-7. Epub 2008 Feb 10.

Department of Chemistry, Columbia University, New York 10027, USA.

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http://dx.doi.org/10.1038/nnano.2008.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747584PMC
March 2008

Binding of Ru(bpy)2(eilatin)2+ to matched and mismatched DNA.

Inorg Chem 2008 Jul 25;47(14):6452-7. Epub 2008 Jun 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ic8006537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747595PMC
July 2008

Targeting abasic sites and single base bulges in DNA with metalloinsertors.

J Am Chem Soc 2008 Jun 21;130(24):7530-1. Epub 2008 May 21.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja801479yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759749PMC
June 2008

DNA binding shifts the redox potential of the transcription factor SoxR.

Proc Natl Acad Sci U S A 2008 Mar 3;105(10):3684-9. Epub 2008 Mar 3.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0800093105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268809PMC
March 2008

Biological contexts for DNA charge transport chemistry.

Curr Opin Chem Biol 2008 Apr 17;12(2):229-37. Epub 2008 Mar 17.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S136759310800032
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http://dx.doi.org/10.1016/j.cbpa.2008.01.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227530PMC
April 2008

Electrical detection of TATA binding protein at DNA-modified microelectrodes.

J Am Chem Soc 2008 Mar 14;130(10):2924-5. Epub 2008 Feb 14.

Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja7106756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747583PMC
March 2008

DNA oxidation by charge transport in mitochondria.

Biochemistry 2008 Feb 12;47(6):1511-7. Epub 2008 Jan 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi701775sDOI Listing
February 2008

Charge migration along the DNA duplex: hole versus electron transport.

J Am Chem Soc 2008 Jan 10;130(4):1152-3. Epub 2008 Jan 10.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/ja710358pDOI Listing
January 2008

A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance.

Proc Natl Acad Sci U S A 2007 Nov 19;104(48):18907-12. Epub 2007 Nov 19.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0709326104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141881PMC
November 2007