Jacqueline Hecht

Jacqueline Hecht

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Jacqueline Hecht

Publications by authors named "Jacqueline Hecht"

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Novel mTORC1 Mechanism Suggests Therapeutic Targets for COMPopathies.

Am J Pathol 2019 Jan;189(1):132-146

Department of Pediatrics, McGovern Medical School, University of Texas Health Science Center, Houston, Texas; School of Dentistry, University of Texas Health Science Center, Houston, Texas.

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http://dx.doi.org/10.1016/j.ajpath.2018.09.008DOI Listing
January 2019

Multicenter study of mortality in achondroplasia.

Am J Med Genet A 2018 Nov 1;176(11):2359-2364. Epub 2018 Oct 1.

Department of Pediatrics, McGovern Medical School at UTHealth, Houston, Texas.

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http://doi.wiley.com/10.1002/ajmg.a.40528
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http://dx.doi.org/10.1002/ajmg.a.40528DOI Listing
November 2018

Cartilage oligomeric matrix protein: COMPopathies and beyond.

Matrix Biol 2018 10 9;71-72:161-173. Epub 2018 Mar 9.

McGovern Medical School, UTHealth, Department of Pediatrics, United States; UTHealth, School of Dentistry, United States.

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http://dx.doi.org/10.1016/j.matbio.2018.02.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129439PMC
October 2018

Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes.

Eur J Hum Genet 2018 Oct 13;26(10):1441-1450. Epub 2018 Jun 13.

Center for Craniofacial Research, University of Texas Health Science Center at Houston (UTHealth) School of Dentistry, Houston, TX, 77054, USA.

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http://dx.doi.org/10.1038/s41431-018-0192-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138754PMC
October 2018

Mapping genetic variants for cranial vault shape in humans.

PLoS One 2018 26;13(4):e0196148. Epub 2018 Apr 26.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196148PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919379PMC
July 2018

BRCA1 and BRCA2 gene variants and nonsyndromic cleft lip/palate.

Birth Defects Res 2018 Jul 19;110(12):1043-1048. Epub 2018 Jun 19.

Center for Craniofacial Research, UTHealth School of Dentistry at Houston, Houston TX, USA.

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http://dx.doi.org/10.1002/bdr2.1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105370PMC
July 2018

Soft tissue nasal asymmetry as an indicator of orofacial cleft predisposition.

Am J Med Genet A 2018 Jun 16;176(6):1296-1303. Epub 2018 Apr 16.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/ajmg.a.38688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992056PMC
June 2018

Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.

Am J Hum Genet 2017 Dec 30;101(6):913-924. Epub 2017 Nov 30.

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Anthropology, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812923PMC
December 2017

Role of WNT10A in failure of tooth development in humans and zebrafish.

Mol Genet Genomic Med 2017 11 14;5(6):730-741. Epub 2017 Sep 14.

Pediatric Research Center, University of Texas Health Science Center at Houston Medical School, Houston, Texas.

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http://dx.doi.org/10.1002/mgg3.332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702573PMC
November 2017

Novel therapeutic interventions for pseudoachondroplasia.

Bone 2017 Sep 21;102:60-68. Epub 2017 Mar 21.

McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, United States; School of Dentistry University of Texas Heath, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.bone.2017.03.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168010PMC
September 2017

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

Mol Ther 2017 03 3;25(3):705-714. Epub 2017 Feb 3.

Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.ymthe.2016.12.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363192PMC
March 2017

Functional Assessment of Clubfoot Associated HOXA9, TPM1, and TPM2 Variants Suggests a Potential Gene Regulation Mechanism.

Clin Orthop Relat Res 2016 Jul 28;474(7):1726-35. Epub 2016 Mar 28.

Department of Pediatrics, UTHealth McGovern Medical School, 6431 Fannin St., MSB 3.306, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11999-016-4788-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887369PMC
July 2016

Deletions of 5' HOXC genes are associated with lower extremity malformations, including clubfoot and vertical talus.

J Med Genet 2016 Apr 4;53(4):250-5. Epub 2016 Jan 4.

Department of Orthopedic Surgery, Washington University, St. Louis, Missouri, USA Department of Neurology, Washington University, St. Louis, Missouri, USA Department of Pediatrics, Washington University, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1136/jmedgenet-2015-103505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955942PMC
April 2016

A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.

Am J Hum Genet 2016 Apr 24;98(4):744-54. Epub 2016 Mar 24.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Clinical and Translational Science, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833215PMC
April 2016

Using the 3D Facial Norms Database to investigate craniofacial sexual dimorphism in healthy children, adolescents, and adults.

Biol Sex Differ 2016 22;7:23. Epub 2016 Apr 22.

Department of Anthropology, University of Pittsburgh, Pittsburgh, PA USA ; Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, 100 Technology Drive, Suite 500, Pittsburgh, PA 15219 USA.

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http://dx.doi.org/10.1186/s13293-016-0076-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841054PMC
April 2016

Pseudoachondroplasia and painful sequelae.

Am J Med Genet A 2015 Nov 14;167A(11):2618-22. Epub 2015 Jul 14.

Medical School, University of Texas Health Science Center at Houston, Texas.

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http://dx.doi.org/10.1002/ajmg.a.37253DOI Listing
November 2015

Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development.

Genesis 2015 Oct 5;53(10):660-7. Epub 2015 Sep 5.

Pediatric Research Center, Department of Pediatrics, The University of Texas Medical School, Houston, Texas.

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http://dx.doi.org/10.1002/dvg.22897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258193PMC
October 2015

Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family.

Mol Genet Genomic Med 2015 Sep 7;3(5):440-51. Epub 2015 May 7.

Department of Pediatrics, University of Texas Medical School at Houston Houston, Texas ; Graduate School of Biomedical Sciences, University of Texas Health Science Center Houston, Texas ; University of Texas School of Dentistry at Houston Houston, Texas.

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http://dx.doi.org/10.1002/mgg3.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585452PMC
September 2015

Antioxidant and anti-inflammatory agents mitigate pathology in a mouse model of pseudoachondroplasia.

Hum Mol Genet 2015 Jul 9;24(14):3918-28. Epub 2015 Apr 9.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, USA and Shriners Hospital for Children, Houston, TX, USA.

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http://dx.doi.org/10.1093/hmg/ddv122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476442PMC
July 2015

The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis.

Bone 2015 Mar 9;72:123-7. Epub 2014 Dec 9.

Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2014.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300120PMC
March 2015

Essential hypertension vs. secondary hypertension among children.

Am J Hypertens 2015 Jan 18;28(1):73-80. Epub 2014 May 18.

Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center, Houston, Texas.

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http://dx.doi.org/10.1093/ajh/hpu083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318949PMC
January 2015

Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate.

Birth Defects Res A Clin Mol Teratol 2014 Sep 27;100(9):679-85. Epub 2014 Aug 27.

Department of Endodontics, University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas; Craniofacial Research Center, University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas.

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http://dx.doi.org/10.1002/bdra.23286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623315PMC
September 2014

Etiopathogenesis of equinovarus foot malformations.

Eur J Med Genet 2014 Aug 13;57(8):473-9. Epub 2014 Jun 13.

University of Texas Medical School at Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmg.2014.06.001DOI Listing
August 2014

Pseudoachondroplasia/COMP - translating from the bench to the bedside.

Matrix Biol 2014 Jul 2;37:167-73. Epub 2014 Jun 2.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77030, USA; Shriners Hospital for Children, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.matbio.2014.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209947PMC
July 2014

Genome-wide association study identifies new disease loci for isolated clubfoot.

J Med Genet 2014 May 25;51(5):334-9. Epub 2014 Mar 25.

Division of Biology and Biomedical Sciences, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1136/jmedgenet-2014-102303DOI Listing
May 2014

Neurologic manifestations of achondroplasia.

Handb Clin Neurol 2014 ;119:551-63

Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Medical School, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/B978-0-7020-4086-3.00036-9DOI Listing
April 2014

Mortality in babies with achondroplasia: revisited.

Birth Defects Res A Clin Mol Teratol 2014 Apr 12;100(4):247-9. Epub 2014 Feb 12.

Pediatric Research Center, Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas.

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http://dx.doi.org/10.1002/bdra.23210DOI Listing
April 2014

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2.

PLoS Genet 2013 3;9(10):e1003846. Epub 2013 Oct 3.

Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany ; Berlin-Brandenburg School for Regenerative Therapies (BSRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1003846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789827PMC
March 2014

Craniofacial abnormalities result from knock down of nonsyndromic clefting gene, crispld2, in zebrafish.

Genesis 2012 Dec 21;50(12):871-81. Epub 2012 Aug 21.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas, USA.

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http://doi.wiley.com/10.1002/dvg.22051
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http://dx.doi.org/10.1002/dvg.22051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535582PMC
December 2012

Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene.

Tissue Eng Part A 2012 Sep 10;18(17-18):1882-9. Epub 2012 Aug 10.

Department of Orthopaedic Surgery, University of California, Davis School of Medicine, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1089/ten.TEA.2011.0497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432897PMC
September 2012

Association of MMP3 and TIMP2 promoter polymorphisms with nonsyndromic oral clefts.

Birth Defects Res A Clin Mol Teratol 2012 Jul 22;94(7):540-8. Epub 2012 Jun 22.

Department of Oral Biology and Center for Craniofacial and Dental Genetics, University of Pittsburgh, Pennsylvania, USA.

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http://doi.wiley.com/10.1002/bdra.23026
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http://dx.doi.org/10.1002/bdra.23026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393800PMC
July 2012

D469del-COMP retention in chondrocytes stimulates caspase-independent necroptosis.

Am J Pathol 2012 Feb 7;180(2):738-48. Epub 2011 Dec 7.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349870PMC
February 2012

Dominant and recessive forms of fibrochondrogenesis resulting from mutations at a second locus, COL11A2.

Am J Med Genet A 2012 Feb 13;158A(2):309-14. Epub 2012 Jan 13.

Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA.

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http://doi.wiley.com/10.1002/ajmg.a.34406
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http://dx.doi.org/10.1002/ajmg.a.34406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264686PMC
February 2012

Association of ABCA4 and MAFB with non-syndromic cleft lip with or without cleft palate.

Am J Med Genet A 2011 Jun 12;155A(6):1469-71. Epub 2011 May 12.

Department of Pediatrics, University of Texas Medical School at Houston, USA.

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http://dx.doi.org/10.1002/ajmg.a.33940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711398PMC
June 2011

Genetic causes of nonsyndromic cleft lip with or without cleft palate.

Adv Otorhinolaryngol 2011 24;70:107-13. Epub 2011 Feb 24.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, Tex., USA.

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http://dx.doi.org/10.1159/000322486DOI Listing
May 2011

Smoking, the xenobiotic pathway, and clubfoot.

Birth Defects Res A Clin Mol Teratol 2011 Jan 1;91(1):20-8. Epub 2010 Dec 1.

Department of Pediatrics, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.

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http://doi.wiley.com/10.1002/bdra.20742
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http://dx.doi.org/10.1002/bdra.20742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799798PMC
January 2011

Nonsyndromic cleft lip and palate: CRISPLD genes and the folate gene pathway connection.

Birth Defects Res A Clin Mol Teratol 2011 Jan 15;91(1):44-9. Epub 2010 Nov 15.

Department of Pediatrics, University of Texas Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/bdra.20737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142894PMC
January 2011

Folate pathway and nonsyndromic cleft lip and palate.

Birth Defects Res A Clin Mol Teratol 2011 Jan 1;91(1):50-60. Epub 2010 Dec 1.

University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1002/bdra.20740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098909PMC
January 2011

RNAi reduces expression and intracellular retention of mutant cartilage oligomeric matrix protein.

PLoS One 2010 Apr 22;5(4):e10302. Epub 2010 Apr 22.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858657PMC
April 2010

Maternal fever during early pregnancy and the risk of oral clefts.

Birth Defects Res A Clin Mol Teratol 2010 Mar;88(3):186-94

The University of Texas Medical School at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/bdra.20646DOI Listing
March 2010

Survival of Texas infants born with trisomies 21, 18, and 13.

Am J Med Genet A 2010 Feb;152A(2):360-6

Kaiser Permanente, San Jose Medical Center, San Jose, California, USA.

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http://dx.doi.org/10.1002/ajmg.a.33156DOI Listing
February 2010

Mutation analysis of the PVRL1 gene in caucasians with nonsyndromic cleft lip/palate.

Genet Test Mol Biomarkers 2009 Oct;13(5):617-21

Department of Medical Biology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

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http://dx.doi.org/10.1089/gtmb.2009.0052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953240PMC
October 2009

Mutation and association analysis of the PVR and PVRL2 genes in patients with non-syndromic cleft lip and palate.

Genet Mol Biol 2009 Jul 1;32(3):466-9. Epub 2009 Sep 1.

Department of Medical Biology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar Turkey.

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http://dx.doi.org/10.1590/S1415-47572009000300007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036061PMC
July 2009

Ribozyme-mediated reduction of wild-type and mutant cartilage oligomeric matrix protein (COMP) mRNA and protein.

RNA 2009 Apr 23;15(4):686-95. Epub 2009 Feb 23.

The Department of Pediatrics, The University of Texas Medical School at Houston, 77030, USA.

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http://dx.doi.org/10.1261/rna.1335909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661830PMC
April 2009

Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate.

Eur J Hum Genet 2009 Feb 20;17(2):195-204. Epub 2008 Aug 20.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77225, USA.

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http://dx.doi.org/10.1038/ejhg.2008.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874967PMC
February 2009

Asymmetric lower-limb malformations in individuals with homeobox PITX1 gene mutation.

Am J Hum Genet 2008 Nov 23;83(5):616-22. Epub 2008 Oct 23.

Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO 63119, USA.

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http://dx.doi.org/10.1016/j.ajhg.2008.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668044PMC
November 2008

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

Am J Pathol 2008 Jun 8;172(6):1664-74. Epub 2008 May 8.

Department of Pediatrics, University of Texas Medical School, 6431 Fannin, Houston, TX 77030, USA.

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http://dx.doi.org/10.2353/ajpath.2008.071094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408425PMC
June 2008

COMP mutations: domain-dependent relationship between abnormal chondrocyte trafficking and clinical PSACH and MED phenotypes.

J Cell Biochem 2008 Feb;103(3):778-87

Department of Cell Biology and Anatomy, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA.

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http://dx.doi.org/10.1002/jcb.21445DOI Listing
February 2008

Mortality in achondroplasia study: a 42-year follow-up.

Am J Med Genet A 2007 Nov;143A(21):2502-11

Department of Pediatrics, University of Texas Health Science Center at Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/ajmg.a.31919DOI Listing
November 2007

NAT2 variation and idiopathic talipes equinovarus (clubfoot).

Am J Med Genet A 2007 Oct;143A(19):2285-91

Department of Pediatrics, University of Texas Medical School, Houston, Texas 77225, USA.

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http://dx.doi.org/10.1002/ajmg.a.31927DOI Listing
October 2007

Computational identification and functional validation of regulatory motifs in cartilage-expressed genes.

Genome Res 2007 Oct 4;17(10):1438-47. Epub 2007 Sep 4.

Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1101/gr.6224007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1987341PMC
October 2007

Apoptotic gene analysis in idiopathic talipes equinovarus (clubfoot).

Clin Orthop Relat Res 2007 Sep;462:32-7

University of Texas Health Science Center, Houston Graduate School of Biomedical Sciences, Houston, TX, USA.

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http://dx.doi.org/10.1097/BLO.0b013e318073c2d9DOI Listing
September 2007

CRISPLD2: a novel NSCLP candidate gene.

Hum Mol Genet 2007 Sep 5;16(18):2241-8. Epub 2007 Jul 5.

Department of Pediatrics, University of Texas Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/hmg/ddm176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755375PMC
September 2007

Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan.

J Biol Chem 2007 Aug 22;282(34):24591-8. Epub 2007 Jun 22.

Cartilage Biology and Orthopaedics Branch, NIAMS, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M611390200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905148PMC
August 2007

Achondroplasia.

Lancet 2007 Jul;370(9582):162-172

Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736076109
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http://dx.doi.org/10.1016/S0140-6736(07)61090-3DOI Listing
July 2007

Unique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes.

Am J Pathol 2007 Jan;170(1):293-300

Department of Pediatrics, University of Texas-Houston Medical School, 6431 Fannin St., MSB 3.136, Houston, TX 77030, USA.

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http://dx.doi.org/10.2353/ajpath.2007.060530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762700PMC
January 2007

Expression of mutant cartilage oligomeric matrix protein in human chondrocytes induces the pseudoachondroplasia phenotype.

J Orthop Res 2006 Apr;24(4):700-7

Department of Pediatrics, University of Texas Medical School at Houston, University of Texas, 6431 Fannin Street, MSB 3.136, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/jor.20100DOI Listing
April 2006

Retention of the matricellular protein SPARC in the endoplasmic reticulum of chondrocytes from patients with pseudoachondroplasia.

J Histochem Cytochem 2006 Mar 14;54(3):269-74. Epub 2005 Nov 14.

Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1369/jhc.5C6834.2005DOI Listing
March 2006

In vivo human Cartilage oligomeric matrix protein (COMP) promoter activity.

Matrix Biol 2005 Dec 7;24(8):539-49. Epub 2005 Oct 7.

Department of Pediatrics, University of Texas Medical School at Houston, 6431 Fannin, 77030, USA.

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http://dx.doi.org/10.1016/j.matbio.2005.07.007DOI Listing
December 2005

Variation in CASP10 gene is associated with idiopathic talipes equinovarus.

J Pediatr Orthop 2005 Sep-Oct;25(5):598-602

University of Texas-Houston School of Public Health, Houston, TX 77225, USA.

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November 2005

Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.

J Biol Chem 2005 Sep 28;280(38):32655-61. Epub 2005 Jul 28.

Department of Orthopaedic Surgery, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M504778200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896261PMC
September 2005

Variation in IRF6 contributes to nonsyndromic cleft lip and palate.

Am J Med Genet A 2005 Sep;137A(3):259-62

University of Virginia, Charlottesville, USA.

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http://dx.doi.org/10.1002/ajmg.a.30887DOI Listing
September 2005

Heparan sulfate proteoglycans: key players in cartilage biology.

Crit Rev Eukaryot Gene Expr 2005 ;15(1):29-48

Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.

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August 2005

Hereditary multiple exostosis and pain.

J Pediatr Orthop 2005 May-Jun;25(3):369-76

Department of Pediatrics, University of Texas-Houston Medical School, Houston, TX 77225, USA.

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July 2005

Racial-ethnic differences in genetic amniocentesis uptake.

J Genet Couns 2005 Jun;14(3):189-95

Genzyme Genetics, Austin, Texas 78628, USA.

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http://dx.doi.org/10.1007/s10897-005-0641-5DOI Listing
June 2005

Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes.

Differentiation 2005 Jun;73(5):212-21

Department of Pediatrics, University of Texas-Houston Medical School, 6431 Fannin St. MSB 3.136, Houston, TX 77030, USA.

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http://dx.doi.org/10.1111/j.1432-0436.2005.00025.xDOI Listing
June 2005

Prevalence of nonsyndromic oral clefts in Texas: 1995-1999.

Am J Med Genet A 2005 May;134(4):368-72

University of Texas Health Sciences Center, Houston School of Public Health, Houston, Texas, USA.

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http://dx.doi.org/10.1002/ajmg.a.30618DOI Listing
May 2005

Idiopathic talipes equinovarus (ITEV) (clubfeet) in Texas.

Am J Med Genet A 2005 Feb;132A(4):376-80

University of Texas Health Sciences Center Houston School of Public Health, Houston, Texas, USA.

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http://dx.doi.org/10.1002/ajmg.a.30505DOI Listing
February 2005

COMP mutations, chondrocyte function and cartilage matrix.

Matrix Biol 2005 Jan 18;23(8):525-33. Epub 2004 Nov 18.

Department of Pediatrics, University of Texas-Houston Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.matbio.2004.09.006DOI Listing
January 2005