Jacob Stewart-Ornstein

Jacob Stewart-Ornstein

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Jacob Stewart-Ornstein

Jacob Stewart-Ornstein

Publications by authors named "Jacob Stewart-Ornstein"

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Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.

Mol Cell 2018 Aug 26;71(4):581-591.e5. Epub 2018 Jul 26.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282757PMC
August 2018

p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.

Nat Struct Mol Biol 2017 Oct 21;24(10):840-847. Epub 2017 Aug 21.

Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nsmb.3452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629117PMC
October 2017

Conservation and Divergence of p53 Oscillation Dynamics across Species.

Cell Syst 2017 Oct 18;5(4):410-417.e4. Epub 2017 Oct 18.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687840PMC
October 2017

p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.

Sci Signal 2017 Apr 25;10(476). Epub 2017 Apr 25.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.aah6671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504473PMC
April 2017

Integrating genomic information and signaling dynamics for efficient cancer therapy.

Curr Opin Syst Biol 2017 Feb 19;1:38-43. Epub 2016 Dec 19.

Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.coisb.2016.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608455PMC
February 2017

Model-guided optogenetic study of PKA signaling in budding yeast.

Mol Biol Cell 2017 01 9;28(1):221-227. Epub 2016 Nov 9.

Department of Biochemistry and Biophysics, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158

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http://dx.doi.org/10.1091/mbc.E16-06-0354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221627PMC
January 2017

Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit.

Cell Rep 2016 Feb 11;14(7):1800-1811. Epub 2016 Feb 11.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(16)30023-7.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471630023
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http://dx.doi.org/10.1016/j.celrep.2016.01.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154611PMC
February 2016

Single-cell analysis of circadian dynamics in tissue explants.

Mol Biol Cell 2015 Nov 12;26(22):3940-5. Epub 2015 Aug 12.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115

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http://dx.doi.org/10.1091/mbc.E15-06-0403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710227PMC
November 2015

Using dynamic noise propagation to infer causal regulatory relationships in biochemical networks.

ACS Synth Biol 2015 Mar 11;4(3):258-64. Epub 2014 Jul 11.

∥The California Institute for Quantitative Biosciences, San Francisco, California 94158, United States.

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http://dx.doi.org/10.1021/sb5000059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384829PMC
March 2015

Msn2 coordinates a stoichiometric gene expression program.

Curr Biol 2013 Dec 7;23(23):2336-45. Epub 2013 Nov 7.

Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143,USA; Howard Hughes Medical Institute, St. Louis, MO 63110, USA; The California Institute for Quantitative Biosciences, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2013.09.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072881PMC
December 2013

Building robust functionality in synthetic circuits using engineered feedback regulation.

Curr Opin Biotechnol 2013 Aug 6;24(4):790-6. Epub 2013 Apr 6.

Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.copbio.2013.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732497PMC
August 2013

Formation of subnuclear foci is a unique spatial behavior of mating MAPKs during hyperosmotic stress.

Cell Rep 2013 Feb 14;3(2):328-34. Epub 2013 Feb 14.

Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616637PMC
February 2013

Stochastic modeling of cellular networks.

Methods Cell Biol 2012 ;110:111-37

Department of Biochemistry and Biophysics, California Institute for Quantitative Biosciences, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/B978-0-12-388403-9.00005-9DOI Listing
July 2012

Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae.

Mol Cell 2012 Feb;45(4):483-93

Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.molcel.2011.11.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327736PMC
February 2012

In silico feedback for in vivo regulation of a gene expression circuit.

Nat Biotechnol 2011 Nov 6;29(12):1114-6. Epub 2011 Nov 6.

Department of Electrical Engineering, ETH Zurich, Automatic Control Laboratory, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nbt.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565053PMC
November 2011

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.

Nat Methods 2008 Aug 11;5(8):711-8. Epub 2008 Jul 11.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 1700 4th Street, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nmeth.1234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756093PMC
August 2008

Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins.

J Phys Chem B 2007 Jul 9;111(26):7691-9. Epub 2007 Jun 9.

BIMR and Department of Chemistry, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1021/jp0720993DOI Listing
July 2007

In situ spatial and time-resolved studies of electrochemical reactions by scanning transmission X-ray microscopy.

Anal Chem 2005 Jun;77(11):3479-87

Centre Energie, Matériaux et Télécommunications, Institut National de la Recherche Scientifique, Varennes, QC, Canada J3X 1S2.

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http://dx.doi.org/10.1021/ac048077jDOI Listing
June 2005