Publications by authors named "Jacob Hochman"

26Publications

Effective Oral Administration of an Antitumorigenic Nanoformulated Titanium Complex.

ChemMedChem 2021 Jan 30;16(1):108-112. Epub 2020 Jul 30.

The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel.

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January 2021

Titanium Tackles the Endoplasmic Reticulum: A First Genomic Study on a Titanium Anticancer Metallodrug.

iScience 2020 Jul 12;23(7):101262. Epub 2020 Jun 12.

Department of Developmental Biology and Cancer Research, Institute of Medical Research-Israel-Canada, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel. Electronic address:

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July 2020

In Vivo Anticancer Activity of a Nontoxic Inert Phenolato Titanium Complex: High Efficacy on Solid Tumors Alone and Combined with Platinum Drugs.

ChemMedChem 2018 11 19;13(21):2290-2296. Epub 2018 Oct 19.

The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel.

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November 2018

Insights into molecular mechanism of action of salan titanium(IV) complex with in vitro and in vivo anticancer activity.

J Inorg Biochem 2016 10 9;163:250-257. Epub 2016 Apr 9.

Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Jerusalem 9190401, Israel. Electronic address:

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October 2016

Specific Design of Titanium(IV) Phenolato Chelates Yields Stable and Accessible, Effective and Selective Anticancer Agents.

Chemistry 2016 Jul 20;22(29):9986-95. Epub 2016 Jun 20.

The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel), Fax: (+972) 2-6584282.

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July 2016

Intraocular Lymphoma Models.

Ocul Oncol Pathol 2015 Apr 9;1(3):214-22. Epub 2015 Apr 9.

Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Md., USA.

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April 2015

Highly Effective and Hydrolytically Stable Vanadium(V) Amino Phenolato Antitumor Agents.

Inorg Chem 2016 Jan 23;55(2):610-8. Epub 2015 Dec 23.

Institute of Chemistry, the Hebrew University of Jerusalem , Jerusalem 9190404, Israel.

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January 2016

Highly Stable Tetra-Phenolato Titanium(IV) Agent Formulated into Nanoparticles Demonstrates Anti-Tumoral Activity and Selectivity.

Molecules 2015 Oct 9;20(10):18526-38. Epub 2015 Oct 9.

The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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October 2015

Central nervous system acute lymphoblastic leukemia: role of natural killer cells.

Blood 2015 May 20;125(22):3420-31. Epub 2015 Apr 20.

Childhood Leukemia Research Section, Department of Pediatric Oncology and the Cancer Research Center, Edmond and Lily Safra Children Hospital and Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel;

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May 2015

Anti-proliferative activity of nano-formulated phenolato titanium(IV) complexes against cancer cells.

ChemMedChem 2014 Jun 26;9(6):1294-8. Epub 2014 Mar 26.

The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel).

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June 2014

Anti-LFA-1 antibodies enhance metastasis of ocular lymphoma to the brain and contralateral eye.

Clin Exp Metastasis 2013 Jan 5;30(1):91-102. Epub 2012 Aug 5.

Department of Cell and Developmental Biology, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.

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January 2013

The signal peptide of mouse mammary tumor virus-env: a phosphoprotein tumor modulator.

Mol Cancer Res 2012 Aug 27;10(8):1077-86. Epub 2012 Jun 27.

Department of Cell and Developmental Biology, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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August 2012

Cytotoxic salan-titanium(IV) complexes: high activity toward a range of sensitive and drug-resistant cell lines, and mechanistic insights.

ChemMedChem 2012 Apr 20;7(4):703-8. Epub 2012 Jan 20.

Institute of Chemistry, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.

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April 2012

The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli.

J Biol Chem 2008 Apr 12;283(15):9966-76. Epub 2008 Feb 12.

Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Mayerhofstrasse 1, Heidelberg, Germany.

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April 2008

International Central Nervous System and Ocular Lymphoma Workshop: recommendations for the future.

Ocul Immunol Inflamm 2006 Jun;14(3):139-44

Laboratory of Immunology, National Eye Institute, NIH, 10 Center Drive, Building 10, Room 10S219, Bethesda, MD, 20892, USA.

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June 2006

Mouse mammary tumor virus Env-derived peptide associates with nucleolar targets in lymphoma, mammary carcinoma, and human breast cancer.

Cancer Res 2005 Aug;65(16):7223-30

Department of Cell and Animal Biology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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August 2005

Murine model of primary intraocular lymphoma.

Invest Ophthalmol Vis Sci 2005 Feb;46(2):415-9

Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892-1857, USA.

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February 2005

The leader peptide of MMTV Env precursor localizes to the nucleoli in MMTV-derived T cell lymphomas and interacts with nucleolar protein B23.

Virology 2003 Aug;313(1):22-32

Department of Cell and Animal Biology, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.

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August 2003