Publications by authors named "Jacob A S Vorstman"

41Publications

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.

Authors:
Isabelle Cleynen Worrawat Engchuan Matthew S Hestand Tracy Heung Aaron M Holleman H Richard Johnston Thomas Monfeuga Donna M McDonald-McGinn Raquel E Gur Bernice E Morrow Ann Swillen Jacob A S Vorstman Carrie E Bearden Eva W C Chow Marianne van den Bree Beverly S Emanuel Joris R Vermeesch Stephen T Warren Michael J Owen Pankaj Chopra David J Cutler Richard Duncan Alex V Kotlar Jennifer G Mulle Anna J Voss Michael E Zwick Alexander Diacou Aaron Golden Tingwei Guo Jhih-Rong Lin Tao Wang Zhengdong Zhang Yingjie Zhao Christian Marshall Daniele Merico Andrea Jin Brenna Lilley Harold I Salmons Oanh Tran Peter Holmans Antonio Pardinas James T R Walters Wolfram Demaerel Erik Boot Nancy J Butcher Gregory A Costain Chelsea Lowther Rens Evers Therese A M J van Amelsvoort Esther van Duin Claudia Vingerhoets Jeroen Breckpot Koen Devriendt Elfi Vergaelen Annick Vogels T Blaine Crowley Daniel E McGinn Edward M Moss Robert J Sharkus Marta Unolt Elaine H Zackai Monica E Calkins Robert S Gallagher Ruben C Gur Sunny X Tang Rosemarie Fritsch Claudia Ornstein Gabriela M Repetto Elemi Breetvelt Sasja N Duijff Ania Fiksinski Hayley Moss Maria Niarchou Kieran C Murphy Sarah E Prasad Eileen M Daly Maria Gudbrandsen Clodagh M Murphy Declan G Murphy Antonio Buzzanca Fabio Di Fabio Maria C Digilio Maria Pontillo Bruno Marino Stefano Vicari Karlene Coleman Joseph F Cubells Opal Y Ousley Miri Carmel Doron Gothelf Ehud Mekori-Domachevsky Elena Michaelovsky Ronnie Weinberger Abraham Weizman Leila Kushan Maria Jalbrzikowski Marco Armando Stéphan Eliez Corrado Sandini Maude Schneider Frédérique Sloan Béna Kevin M Antshel Wanda Fremont Wendy R Kates Raoul Belzeaux Tiffany Busa Nicole Philip Linda E Campbell Kathryn L McCabe Stephen R Hooper Kelly Schoch Vandana Shashi Tony J Simon Flora Tassone Celso Arango David Fraguas Sixto García-Miñaúr Jaume Morey-Canyelles Jordi Rosell Damià H Suñer Jasna Raventos-Simic Michael P Epstein Nigel M Williams Anne S Bassett

Mol Psychiatry 2020 Feb 3. Epub 2020 Feb 3.

Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41380-020-0654-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396297PMC
February 2020

Neurobiological perspective of 22q11.2 deletion syndrome.

Lancet Psychiatry 2019 11 5;6(11):951-960. Epub 2019 Aug 5.

Department of Psychiatry & Neuropsychology, Maastricht University, Maastricht, Netherlands.

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http://dx.doi.org/10.1016/S2215-0366(19)30076-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008533PMC
November 2019

The 22q11.2 deletion syndrome as a model for idiopathic scoliosis - A hypothesis.

Med Hypotheses 2019 Jun 27;127:57-62. Epub 2019 Mar 27.

Department of Orthopaedic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.mehy.2019.03.024DOI Listing
June 2019

Understanding the pediatric psychiatric phenotype of 22q11.2 deletion syndrome.

Am J Med Genet A 2018 10 8;176(10):2182-2191. Epub 2018 Sep 8.

Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://doi.wiley.com/10.1002/ajmg.a.40387
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http://dx.doi.org/10.1002/ajmg.a.40387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209526PMC
October 2018

Double hits in schizophrenia.

Hum Mol Genet 2018 08;27(15):2755-2761

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddy175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049008PMC
August 2018

White matter abnormalities in 22q11.2 deletion syndrome patients showing cognitive decline.

Psychol Med 2018 07 16;48(10):1655-1663. Epub 2017 Nov 16.

Department of Psychiatry,Rudolf Magnus Institute of Neuroscience, University Medical Center,Utrecht,The Netherlands.

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http://dx.doi.org/10.1017/S0033291717003142DOI Listing
July 2018

Autism genetics: opportunities and challenges for clinical translation.

Nat Rev Genet 2017 06 6;18(6):362-376. Epub 2017 Mar 6.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nrg.2017.4DOI Listing
June 2017

[Formula: see text]Executive functioning and its relation to ASD and ADHD symptomatology in 22q11.2 deletion syndrome.

Child Neuropsychol 2018 Jan 9;24(1):1-19. Epub 2016 Sep 9.

a Department of Clinical Child and Adolescent Studies , Leiden University , Leiden , The Netherlands.

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http://dx.doi.org/10.1080/09297049.2016.1221064DOI Listing
January 2018

Genome-wide burden of deleterious coding variants increased in schizophrenia.

Nat Commun 2015 Jul 9;6:7501. Epub 2015 Jul 9.

Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms8501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499856PMC
July 2015

22q11.2 deletion syndrome.

Nat Rev Dis Primers 2015 11 19;1:15071. Epub 2015 Nov 19.

The Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, Toronto General Hospital, University Health Network, and Clinical Genetics Research Program, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://www.nature.com/articles/nrdp201571
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http://dx.doi.org/10.1038/nrdp.2015.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900471PMC
November 2015

Behavioral phenotype in children with 22q11DS: agreement between parents and teachers.

Psychol Assess 2015 Mar 1;27(1):272-9. Epub 2014 Dec 1.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht.

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http://dx.doi.org/10.1037/a0038102DOI Listing
March 2015

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.

Authors:
Dalila Pinto Elsa Delaby Daniele Merico Mafalda Barbosa Alison Merikangas Lambertus Klei Bhooma Thiruvahindrapuram Xiao Xu Robert Ziman Zhuozhi Wang Jacob A S Vorstman Ann Thompson Regina Regan Marion Pilorge Giovanna Pellecchia Alistair T Pagnamenta Bárbara Oliveira Christian R Marshall Tiago R Magalhaes Jennifer K Lowe Jennifer L Howe Anthony J Griswold John Gilbert Eftichia Duketis Beth A Dombroski Maretha V De Jonge Michael Cuccaro Emily L Crawford Catarina T Correia Judith Conroy Inês C Conceição Andreas G Chiocchetti Jillian P Casey Guiqing Cai Christelle Cabrol Nadia Bolshakova Elena Bacchelli Richard Anney Steven Gallinger Michelle Cotterchio Graham Casey Lonnie Zwaigenbaum Kerstin Wittemeyer Kirsty Wing Simon Wallace Herman van Engeland Ana Tryfon Susanne Thomson Latha Soorya Bernadette Rogé Wendy Roberts Fritz Poustka Susana Mouga Nancy Minshew L Alison McInnes Susan G McGrew Catherine Lord Marion Leboyer Ann S Le Couteur Alexander Kolevzon Patricia Jiménez González Suma Jacob Richard Holt Stephen Guter Jonathan Green Andrew Green Christopher Gillberg Bridget A Fernandez Frederico Duque Richard Delorme Geraldine Dawson Pauline Chaste Cátia Café Sean Brennan Thomas Bourgeron Patrick F Bolton Sven Bölte Raphael Bernier Gillian Baird Anthony J Bailey Evdokia Anagnostou Joana Almeida Ellen M Wijsman Veronica J Vieland Astrid M Vicente Gerard D Schellenberg Margaret Pericak-Vance Andrew D Paterson Jeremy R Parr Guiomar Oliveira John I Nurnberger Anthony P Monaco Elena Maestrini Sabine M Klauck Hakon Hakonarson Jonathan L Haines Daniel H Geschwind Christine M Freitag Susan E Folstein Sean Ennis Hilary Coon Agatino Battaglia Peter Szatmari James S Sutcliffe Joachim Hallmayer Michael Gill Edwin H Cook Joseph D Buxbaum Bernie Devlin Louise Gallagher Catalina Betancur Stephen W Scherer

Am J Hum Genet 2014 May 24;94(5):677-94. Epub 2014 Apr 24.

Program in Genetics and Genome Biology, The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada; McLaughlin Centre, University of Toronto, Toronto, ON M5S 1A1, Canada. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(14)00150-5.pdf
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https://hal.archives-ouvertes.fr/inserm-00986225/file/mmc1.p
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http://linkinghub.elsevier.com/retrieve/pii/S000292971400150
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2014.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067558PMC
May 2014

Using genetic findings in autism for the development of new pharmaceutical compounds.

Psychopharmacology (Berl) 2014 Mar 30;231(6):1063-78. Epub 2013 Nov 30.

Department of Psychiatry, Brain Center Rudolf Magnus, A001.468, University Medical Center Utrecht, Heidelberglaan 100, 3485 CX, Utrecht, The Netherlands,

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http://dx.doi.org/10.1007/s00213-013-3334-zDOI Listing
March 2014

Cognitive and behavioral trajectories in 22q11DS from childhood into adolescence: a prospective 6-year follow-up study.

Res Dev Disabil 2013 Sep 29;34(9):2937-45. Epub 2013 Jun 29.

Department of Pediatric Psychology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ridd.2013.06.001DOI Listing
September 2013

Genetic causes of developmental disorders.

Curr Opin Neurol 2013 Apr;26(2):128-36

Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/WCO.0b013e32835f1a30DOI Listing
April 2013

No evidence that common genetic risk variation is shared between schizophrenia and autism.

Am J Med Genet B Neuropsychiatr Genet 2013 Jan 28;162B(1):55-60. Epub 2012 Nov 28.

Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.b.32121DOI Listing
January 2013

Expression of autism spectrum and schizophrenia in patients with a 22q11.2 deletion.

Schizophr Res 2013 Jan 13;143(1):55-9. Epub 2012 Nov 13.

Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.schres.2012.10.010DOI Listing
January 2013

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis.

PLoS One 2012 22;7(6):e37852. Epub 2012 Jun 22.

Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037852PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382234PMC
March 2013

Cognitive development in children with 22q11.2 deletion syndrome.

Br J Psychiatry 2012 Jun;200(6):462-8

Department of Paediatric Psychology, University Medical Centre Utrecht, The Netherlands.

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http://dx.doi.org/10.1192/bjp.bp.111.097139DOI Listing
June 2012

Is there a core neuropsychiatric phenotype in 22q11.2 deletion syndrome?

Curr Opin Neurol 2012 Apr;25(2):131-7

Department of Medical Genetics, University of Cambridge, UK.

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http://dx.doi.org/10.1097/WCO.0b013e328352dd58DOI Listing
April 2012

Proline and COMT status affect visual connectivity in children with 22q11.2 deletion syndrome.

PLoS One 2011 5;6(10):e25882. Epub 2011 Oct 5.

Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187802PMC
February 2012

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.

Authors:
Jillian P Casey Tiago Magalhaes Judith M Conroy Regina Regan Naisha Shah Richard Anney Denis C Shields Brett S Abrahams Joana Almeida Elena Bacchelli Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Patrick F Bolton Thomas Bourgeron Sean Brennan Phil Cali Catarina Correia Christina Corsello Marc Coutanche Geraldine Dawson Maretha de Jonge Richard Delorme Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Suzanne Foley Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jonathan Green Stephen J Guter Hakon Hakonarson Richard Holt Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Janine A Lamb Marion Leboyer Ann Le Couteur Bennett L Leventhal Catherine Lord Sabata C Lund Elena Maestrini Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Alison Merikangas Judith Miller Fiorella Minopoli Ghazala K Mirza Jeff Munson Stanley F Nelson Gudrun Nygren Guiomar Oliveira Alistair T Pagnamenta Katerina Papanikolaou Jeremy R Parr Barbara Parrini Andrew Pickles Dalila Pinto Joseph Piven David J Posey Annemarie Poustka Fritz Poustka Jiannis Ragoussis Bernadette Roge Michael L Rutter Ana F Sequeira Latha Soorya Inês Sousa Nuala Sykes Vera Stoppioni Raffaella Tancredi Maïté Tauber Ann P Thompson Susanne Thomson John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Jacob A S Vorstman Simon Wallace Kai Wang Thomas H Wassink Kathy White Kirsty Wing Kerstin Wittemeyer Brian L Yaspan Lonnie Zwaigenbaum Catalina Betancur Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Daniel H Geschwind Jonathan L Haines Joachim Hallmayer Anthony P Monaco John I Nurnberger Margaret A Pericak-Vance Gerard D Schellenberg Stephen W Scherer James S Sutcliffe Peter Szatmari Veronica J Vieland Ellen M Wijsman Andrew Green Michael Gill Louise Gallagher Astrid Vicente Sean Ennis

Hum Genet 2012 Apr 14;131(4):565-79. Epub 2011 Oct 14.

School of Medicine and Medical Science University College, Dublin, Ireland.

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http://researchrepository.ucd.ie/bitstream/handle/10197/6163
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http://link.springer.com/10.1007/s00439-011-1094-6
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http://dx.doi.org/10.1007/s00439-011-1094-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303079PMC
April 2012

Proline affects brain function in 22q11DS children with the low activity COMT 158 allele.

Neuropsychopharmacology 2009 Feb 3;34(3):739-46. Epub 2008 Sep 3.

Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/npp.2008.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817942PMC
February 2009

Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome.

Am J Med Genet B Neuropsychiatr Genet 2009 Apr;150B(3):430-3

Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.b.30827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127866PMC
April 2009

Prevalence of 22q11.2 deletions in 311 Dutch patients with schizophrenia.

Schizophr Res 2008 Jan 26;98(1-3):84-8. Epub 2007 Oct 26.

Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.schres.2007.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810966PMC
January 2008

Psychopathology in 22q11 deletion syndrome.

J Am Acad Child Adolesc Psychiatry 2007 Aug;46(8):942-944

Department of Child and Adolescent Psychiatry, University Medical Centre, Rudolf Magnus Institute of Neurosciences, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/chi.0b013e318068fc0eDOI Listing
August 2007

The 22q11.2 deletion in children: high rate of autistic disorders and early onset of psychotic symptoms.

J Am Acad Child Adolesc Psychiatry 2006 Sep;45(9):1104-1113

Drs. Vorstman, Swaab, and van Engeland and Ms. Morcus are with the Department of Child and Adolescent Psychiatry; Dr. Heineman-de Boer, Ms. Duijff, and Ms. Klaassen are with the Department of Pediatric Psychology; Dr. Beemer is with the Department of Medical Genetics; Dr. Kahn is with the Department of Psychiatry, University Medical Centre, Utrecht, The Netherlands. Drs. Vorstman, Swaab, Kahn, and van Engeland and Ms. Morcus are also with the Rudolf Magnus Institute of Neurosciences, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/01.chi.0000228131.56956.c1DOI Listing
September 2006