Jaclyn A Biegel

Jaclyn A Biegel

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Jaclyn A Biegel

Publications by authors named "Jaclyn A Biegel"

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Expanding the spectrum of dicer1-associated sarcomas.

Mod Pathol 2019 Sep 19. Epub 2019 Sep 19.

Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41379-019-0366-xDOI Listing
September 2019

Germline genetic landscape of pediatric central nervous system (CNS) tumors.

Neuro Oncol 2019 Jun 19. Epub 2019 Jun 19.

Center for Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1093/neuonc/noz108DOI Listing
June 2019

Case-based review: atypical teratoid/rhabdoid tumor.

Neurooncol Pract 2019 May 5;6(3):163-178. Epub 2018 Oct 5.

Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1093/nop/npy037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656328PMC
May 2019

Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric Malignancies.

Cancer Res 2019 Apr 1;79(7):1318-1330. Epub 2019 Feb 1.

Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-2220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445760PMC
April 2019

A semiautomated whole-exome sequencing workflow leads to increased diagnostic yield and identification of novel candidate variants.

Cold Spring Harb Mol Case Stud 2019 Apr 1;5(2). Epub 2019 Apr 1.

Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1101/mcs.a003756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549575PMC
April 2019

The genomic landscape of pediatric cancers: Implications for diagnosis and treatment.

Science 2019 03;363(6432):1170-1175

Department of Pathology and Laboratory Medicine, Children's Hospital of Los Angeles, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1126/science.aaw3535DOI Listing
March 2019

Rare Pediatric Invasive Gliofibroma Has BRAFV600E Mutation and Transiently Responds to Targeted Therapy Before Progressive Clonal Evolution.

JCO Precis Oncol 2019 27;3. Epub 2019 Mar 27.

Division of Hematology, Oncology, and Blood and Marrow Transplant Program, Children's Center for Cancer and Blood Diseases, Department of Pediatrics, Children's Hospital Los Angeles.

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http://dx.doi.org/10.1200/PO.18.00138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555144PMC
March 2019

Embryonal rhabdomyosarcoma in a patient with a germline CBL pathogenic variant.

Cancer Genet 2019 Feb 30;231-232:62-66. Epub 2018 Dec 30.

Department of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, USA; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.cancergen.2018.12.006DOI Listing
February 2019

Sustained response of three pediatric BRAF mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.

Oncotarget 2019 Jan 11;10(4):551-557. Epub 2019 Jan 11.

Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.26560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355184PMC
January 2019

OncoKids: A Comprehensive Next-Generation Sequencing Panel for Pediatric Malignancies.

J Mol Diagn 2018 11 20;20(6):765-776. Epub 2018 Aug 20.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California; Department of Pathology, Keck School of Medicine of USC, Los Angeles, California.

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https://linkinghub.elsevier.com/retrieve/pii/S15251578183010
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http://dx.doi.org/10.1016/j.jmoldx.2018.06.009DOI Listing
November 2018

Three synchronous malignancies in a patient with DICER1 syndrome.

Eur J Cancer 2018 04 31;93:140-143. Epub 2018 Jan 31.

Division of Hematology, Oncology, and Blood and Marrow Transplantation, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.ejca.2017.12.021DOI Listing
April 2018

Transmission of a germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner.

Cold Spring Harb Mol Case Stud 2018 04 2;4(2). Epub 2018 Apr 2.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1101/mcs.a002576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880265PMC
April 2018

Copy number alterations determined by single nucleotide polymorphism array testing in the clinical laboratory are indicative of gene fusions in pediatric cancer patients.

Genes Chromosomes Cancer 2017 10 1;56(10):730-749. Epub 2017 Jul 1.

Department of Pathology and Laboratory Medicine Children's Hospital of Los Angeles, Center for Personalized Medicine, Los Angeles, California.

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http://dx.doi.org/10.1002/gcc.22477DOI Listing
October 2017

Concurrent myeloid sarcoma, atypical teratoid/rhabdoid tumor, and hypereosinophilia in an infant with a germline SMARCB1 mutation.

Pediatr Blood Cancer 2017 Sep 23;64(9). Epub 2017 Jan 23.

Division of Hematology/Oncology, Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, Georgia.

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http://doi.wiley.com/10.1002/pbc.26460
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http://dx.doi.org/10.1002/pbc.26460DOI Listing
September 2017

Inherited germline ATRX mutation in two brothers with ATR-X syndrome and osteosarcoma.

Am J Med Genet A 2017 May 28;173(5):1390-1395. Epub 2017 Mar 28.

Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.

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http://doi.wiley.com/10.1002/ajmg.a.38184
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http://dx.doi.org/10.1002/ajmg.a.38184DOI Listing
May 2017

Clonal hematopoiesis in patients with dyskeratosis congenita.

Am J Hematol 2016 12 21;91(12):1227-1233. Epub 2016 Oct 21.

Comprehensive Bone Marrow Failure Center, Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104.

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http://dx.doi.org/10.1002/ajh.24552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118079PMC
December 2016

Unique Familial MLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings.

Pediatr Blood Cancer 2016 07 21;63(7):1175-80. Epub 2016 Mar 21.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.25957DOI Listing
July 2016

Biology and Treatment of Rhabdoid Tumor.

Crit Rev Oncog 2015 ;20(3-4):199-216

Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles; Keck School of Medicine, University of Southern California, Los Angeles, Ca.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087667PMC
June 2016

Clonal evolution and clinical significance of copy number neutral loss of heterozygosity of chromosome arm 6p in acquired aplastic anemia.

Cancer Genet 2016 Jan-Feb;209(1-2):1-10. Epub 2015 Oct 30.

Comprehensive Bone Marrow Failure Center, Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738084PMC
June 2016

Atypical teratoid/rhabdoid tumors-current concepts, advances in biology, and potential future therapies.

Neuro Oncol 2016 06 10;18(6):764-78. Epub 2016 Jan 10.

Children's Hospital and Swabian Children's Cancer Center, Augsburg, Germany (M.C.F.); Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California (J.A.B.); INSERM U830, Laboratory of Genetics and Biology of Cancers, and Department of Pediatric Oncology, Curie Institute, Paris, France (F.B.); Comprehensive Cancer Center and Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee (C.W.M.R.); Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.N.C.); Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts (S.N.C.); Department of Pediatrics, Harvard Medical School, Boston, Massachusetts (S.N.C.).

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http://dx.doi.org/10.1093/neuonc/nov264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864253PMC
June 2016

Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status.

J Neuropathol Exp Neurol 2016 Apr 4;75(4):306-15. Epub 2016 Mar 4.

From the Department of Pediatrics (JJR, AJW), Department of Pathology and Laboratory Medicine (MS), and Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (AJW); Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania (JJR); Department of Bio- statistics and Epidemiology, Perelman School of Medicine at the Univer- sity of Pennsylvania, Philadelphia, Pennsylvania (LY); Department of Neurosurgery, Temple University School of Medicine, Philadelphia, Pennsylvania (TMF); Department of Pathology and Laboratory Medicine, Children s Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California (JAB).

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http://dx.doi.org/10.1093/jnen/nlw001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009478PMC
April 2016

Report of a patient with a constitutional missense mutation in SMARCB1, Coffin-Siris phenotype, and schwannomatosis.

Am J Med Genet A 2015 Dec 14;167A(12):3186-91. Epub 2015 Sep 14.

Division of Pediatric Hematology and Oncology, University of Minnesota Masonic Children's Hospital, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/ajmg.a.37356DOI Listing
December 2015

SMARCB1-deficient Vulvar Neoplasms: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 14 Cases.

Am J Surg Pathol 2015 Jun;39(6):836-49

*Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN ‡Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia ¶Department of Pediatrics at The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA §Department of Pathology, Carolinas Medical Center, Charlotte, NC ∥Department of Pathology, Massachusetts General Hospital, Boston, MA †Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.

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http://dx.doi.org/10.1097/PAS.0000000000000397DOI Listing
June 2015

Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia.

Cancer Genet 2015 Apr 2;208(4):115-28. Epub 2015 Feb 2.

Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Comprehensive Bone Marrow Failure Center, Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.cancergen.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433860PMC
April 2015

Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.

Brain Pathol 2015 Mar 12;25(2):182-92. Epub 2014 Sep 12.

Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1111/bpa.12167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282976PMC
March 2015

Mixed Phenotype Acute Leukemia with Low Hypodiploidy in a Pediatric Patient.

J Pediatr Oncol 2015;3(1):24-28. Epub 2015 Mar 25.

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.14205/2309-3021.2015.03.01.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626005PMC
March 2015

Malignant rhabdoid tumor of the bladder and ganglioglioma in a 14 year-old male with a germline 22q11.2 deletion.

Cancer Genet 2014 Sep 21;207(9):415-9. Epub 2014 May 21.

Division of Oncology, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Department of Pediatrics, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.05.007DOI Listing
September 2014

SWI/SNF chromatin remodeling complexes and cancer.

Am J Med Genet C Semin Med Genet 2014 Sep 28;166C(3):350-66. Epub 2014 Aug 28.

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http://doi.wiley.com/10.1002/ajmg.c.31410
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http://dx.doi.org/10.1002/ajmg.c.31410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516040PMC
September 2014

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors.

Cancer Genet 2014 Apr 15;207(4):111-23. Epub 2014 Mar 15.

Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161453PMC
April 2014

Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes.

Br J Haematol 2014 Jan 14;164(1):73-82. Epub 2013 Oct 14.

Division of Hematology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; Comprehensive Bone Marrow Failure Center, Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.12603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986350PMC
January 2014

Cribriform neuroepithelial tumor arising in the lateral ventricle.

Pediatr Dev Pathol 2013 Jul-Aug;16(4):301-7. Epub 2013 Mar 15.

Department of Pathology and Laboratory Medicine, Ohio State University College of Medicine, Columbus, OH, USA.

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http://journals.sagepub.com/doi/10.2350/12-12-1287-CR.1
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http://dx.doi.org/10.2350/12-12-1287-CR.1DOI Listing
October 2013

Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients.

Am J Hematol 2013 Oct 23;88(10):862-7. Epub 2013 Jul 23.

Division of Hematology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.23521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983712PMC
October 2013

Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions.

Mod Pathol 2013 Mar 12;26(3):385-92. Epub 2012 Oct 12.

Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/modpathol.2012.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556344PMC
March 2013

Proximal-type Epithelioid Sarcoma of the Head and Neck (HN): A Study with Immunohistochemical and Molecular Analysis of SMARCB1.

J Clin Exp Oncol 2013 ;2(2)

Anatomic Pathology, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.4172/2324-9110.1000106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846256PMC
January 2013

Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors.

Pediatr Blood Cancer 2012 Dec 19;59(7):1155-7. Epub 2012 Sep 19.

Director, Pediatric Medical Neuro-Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Pediatric Hematology/Oncology, Boston, MA 02215, USA.

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http://dx.doi.org/10.1002/pbc.24315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538080PMC
December 2012

Clinical utilization of high-resolution single nucleotide polymorphism based oligonucleotide arrays in diagnostic studies of pediatric patients with solid tumors.

Cancer Genet 2012 Jan-Feb;205(1-2):42-54

Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.cancergen.2012.01.014DOI Listing
May 2012

Novel cell lines established from pediatric brain tumors.

J Neurooncol 2012 Apr 27;107(2):269-80. Epub 2011 Nov 27.

Developmental Therapeutics Program, Division of Hematology-Oncology, USC-CHLA Institute for Pediatric Clinical Research, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://link.springer.com/10.1007/s11060-011-0756-5
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http://dx.doi.org/10.1007/s11060-011-0756-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379550PMC
April 2012

Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies.

Congenit Heart Dis 2011 Nov-Dec;6(6):592-602. Epub 2011 Oct 20.

Divisions of Cardiology Human Genetics Oncology Center for Applied Genomics Center for Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/j.1747-0803.2011.00582.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575121PMC
March 2012

Ganglioglioma arising from dysplastic cortex.

Epilepsia 2011 Sep 10;52(9):e106-8. Epub 2011 Jun 10.

Department of Pediatrics and Neurology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1111/j.1528-1167.2011.03124.xDOI Listing
September 2011

Clinicopathologic comparison of familial versus sporadic atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system.

Pediatr Blood Cancer 2011 Jul 16;56(7):1026-31. Epub 2010 Sep 16.

Division of Hematology-Oncology, Department of Pediatrics, University of Utah School of Medicine and Primary Children's Medical Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1002/pbc.22757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210729PMC
July 2011

p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors.

J Neuropathol Exp Neurol 2011 Jul;70(7):596-609

Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31822146caDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145456PMC
July 2011

Temporal lobe pleomorphic xanthoastrocytoma and acquired BRAF mutation in an adolescent with the constitutional 22q11.2 deletion syndrome.

J Neurooncol 2011 May 21;102(3):509-14. Epub 2010 Aug 21.

Neurosciences Program, Hematology and Oncology Center, Cook Children's Medical Center, 901 Seventh Avenue, Suite 220, Fort Worth, TX 76104, USA.

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http://dx.doi.org/10.1007/s11060-010-0350-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998545PMC
May 2011

Educational paper: screening in cancer predisposition syndromes: guidelines for the general pediatrician.

Eur J Pediatr 2011 Mar 6;170(3):285-94. Epub 2011 Jan 6.

Division of Oncology, Children's Hospital of Philadelphia, Colket Translational Research Building, Rm 3012, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00431-010-1377-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086787PMC
March 2011

Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors.

Pediatr Blood Cancer 2011 Jan;56(1):7-15

Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/pbc.22831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086793PMC
January 2011

Implementation of high resolution single nucleotide polymorphism array analysis as a clinical test for patients with hematologic malignancies.

Cancer Genet 2011 Jan;204(1):26-38

Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.10.007DOI Listing
January 2011

Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.

Neuro Oncol 2010 Jul 14;12(7):621-30. Epub 2010 Feb 14.

The Children's Hospital of Philadelphia, Room 1002 Abramson Research Building, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/neuonc/noq007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940652PMC
July 2010

ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.

Cancer Res 2010 Feb 26;70(3):1236-46. Epub 2010 Jan 26.

The Wistar Institute, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2249DOI Listing
February 2010

Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor.

J Neurosurg Pediatr 2010 Jan;5(1):75-9

Department of Neurosurgery, Children's Hospital of Philadelphia, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-4399, USA.

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http://dx.doi.org/10.3171/2009.8.PEDS08421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840717PMC
January 2010

ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.

Pediatr Dev Pathol 2009 Jul-Aug;12(4):275-83

Department of Pathology, A. I. DuPont Hospital for Children, Wilmington, DE, USA.

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http://dx.doi.org/10.2350/08-03-0434.1DOI Listing
November 2009

SMARCB1/INI1 alterations and hepatoblastoma: another extrarenal rhabdoid tumor revealed?

Pediatr Blood Cancer 2009 Mar;52(3):312-3

Department of Pathology, Laboratory Medicine and Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1002/pbc.21893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094586PMC
March 2009

The role of SMARCB1/INI1 in development of rhabdoid tumor.

Cancer Biol Ther 2009 Mar 29;8(5):412-6. Epub 2009 Mar 29.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709499PMC
http://dx.doi.org/10.4161/cbt.8.5.8019DOI Listing
March 2009

Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy.

Genome Res 2009 Feb 13;19(2):276-83. Epub 2009 Jan 13.

Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, and Abramson Family Cancer Research Institute, Philadelphia, Pennsylvania 19104-4318, USA.

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http://dx.doi.org/10.1101/gr.075671.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652209PMC
February 2009

Loss of INI1 expression defines a unique subset of pediatric undifferentiated soft tissue sarcomas.

Mod Pathol 2009 Jan 7;22(1):142-50. Epub 2008 Nov 7.

Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/modpathol.2008.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094585PMC
January 2009

Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.

Mol Cell Biol 2008 Oct 18;28(20):6223-33. Epub 2008 Aug 18.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1128/MCB.00658-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577431PMC
October 2008

Atypical teratoid/rhabdoid tumor arising from the third cranial nerve.

J Neuroophthalmol 2008 Sep;28(3):207-11

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine and Miami Children's Hospital, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1097/WNO.0b013e318183c770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839362PMC
September 2008

Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of rhabdoid tumors.

Clin Cancer Res 2008 Feb;14(4):1218-27

Department of Oncology, University of Calgary, the Tom Baker Cancer Centre, and the Clark H. Smith Brain Tumour Research Centre, Calgary, Alberta, Canada.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-07-1330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844789PMC
February 2008

Malignant rhabdoid tumor mimicking hepatoblastoma: a case report and literature review.

Pediatr Dev Pathol 2007 Sep-Oct;10(5):409-15

Division of Hematology/Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.2350/06-08-0155.1DOI Listing
December 2007

Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma.

J Neurooncol 2007 Sep 13;84(2):217-22. Epub 2007 Apr 13.

Division of Neuropathology, Department of Neurological Sciences, Christian Medical College, Vellore, India.

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http://dx.doi.org/10.1007/s11060-007-9361-zDOI Listing
September 2007

Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging.

J Neurosurg 2007 Sep;107(3):600-9

Department of Neurosurgery, The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.3171/JNS-07/09/0600DOI Listing
September 2007

Atypical teratoid/rhabdoid tumor of the spine in an adult: case report and review of the literature.

J Neurooncol 2007 Aug 22;84(1):49-55. Epub 2007 Mar 22.

Department of Pathology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1007/s11060-007-9339-xDOI Listing
August 2007

Atypical teratoid/rhabdoid tumor in a patient with Beckwith-Wiedemann syndrome.

Am J Med Genet A 2007 Aug;143A(15):1767-70

Department of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1002/ajmg.a.31843
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http://dx.doi.org/10.1002/ajmg.a.31843DOI Listing
August 2007

Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium.

Hum Pathol 2007 Jun 21;38(6):935-9. Epub 2007 Mar 21.

Department of Pathology, Scott and White Memorial Hospital and Clinic, Scott, Sherwood and Brindley Foundation, Texas A&M University Health Science Center College of Medicine, Temple, TX 76508, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963314PMC
http://dx.doi.org/10.1016/j.humpath.2006.12.003DOI Listing
June 2007

Predisposition to atypical teratoid/rhabdoid tumor due to an inherited INI1 mutation.

Pediatr Blood Cancer 2006 Sep;47(3):279-84

Department of Radiation Oncology, Tulane University, New Orleans, Los Angeles, USA.

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http://dx.doi.org/10.1002/pbc.20622DOI Listing
September 2006

Parental heat exposure and risk of childhood brain tumor: a Children's Oncology Group study.

Am J Epidemiol 2006 Aug 14;164(3):222-31. Epub 2006 Jun 14.

Division of Oncology, Children's Hospital of Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/aje/kwj174DOI Listing
August 2006

Atypical teratoid/rhabdoid tumor evolving from an optic pathway ganglioglioma: case study.

Neuro Oncol 2006 Jan;8(1):79-82

Department of Neurology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1215/S1522851705000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871926PMC
January 2006

Molecular genetics of atypical teratoid/rhabdoid tumor.

Authors:
Jaclyn A Biegel

Neurosurg Focus 2006 Jan 15;20(1):E11. Epub 2006 Jan 15.

Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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January 2006

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.

Genes Chromosomes Cancer 2005 Aug;43(4):390-403

Division of Oncology, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1002/gcc.20198DOI Listing
August 2005

INI1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomas.

Mod Pathol 2005 Jul;18(7):951-8

Department of Pathology, Washington University School of Medicine, St Louis, MO 63001-1093, USA.

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http://dx.doi.org/10.1038/modpathol.3800375DOI Listing
July 2005

Chromophobe renal cell carcinoma in a pediatric living-related kidney transplant recipient.

Am J Kidney Dis 2005 Jun;45(6):e105-8

Department of Surgery, The Children's Hospital of Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1053/j.ajkd.2005.03.012DOI Listing
June 2005

INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma.

J Neuropathol Exp Neurol 2005 May;64(5):391-7

Department of Pathology, University of Pennsylvania School of Medicine and Children's Hospital of Philadelphia, 3615 Civic Center Blvd., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/jnen/64.5.391DOI Listing
May 2005

Early molecular detection of central nervous system relapse in a child with systemic anaplastic large cell lymphoma: case report and review of the literature.

Pediatr Blood Cancer 2005 Apr;44(4):400-6

Division of Hematology and Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104-4399, USA.

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http://dx.doi.org/10.1002/pbc.20250DOI Listing
April 2005

Chromosome 22q deletions in atypical teratoid/rhabdoid tumors in adults.

Brain Pathol 2005 Jan;15(1):23-8

Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9073, USA.

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January 2005