Publications by authors named "Jack Taunton"

100Publications

Bilateral difference between lower limbs in children practicing laterally dominant vs. non-laterally dominant sports.

Eur J Sport Sci 2020 Sep 12:1-9. Epub 2020 Sep 12.

School of Kinesiology, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1080/17461391.2020.1814425DOI Listing
September 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.

bioRxiv 2020 Mar 22. Epub 2020 Mar 22.

QBI COVID-19 Research Group (QCRG), San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1101/2020.03.22.002386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239059PMC
March 2020

Iliotibial band syndrome rehabilitation in female runners: a pilot randomized study.

J Orthop Surg Res 2020 May 24;15(1):188. Epub 2020 May 24.

Allan McGavin Sports Medicine Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1186/s13018-020-01713-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247177PMC
May 2020

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

Authors:
David E Gordon Gwendolyn M Jang Mehdi Bouhaddou Jiewei Xu Kirsten Obernier Kris M White Matthew J O'Meara Veronica V Rezelj Jeffrey Z Guo Danielle L Swaney Tia A Tummino Ruth Hüttenhain Robyn M Kaake Alicia L Richards Beril Tutuncuoglu Helene Foussard Jyoti Batra Kelsey Haas Maya Modak Minkyu Kim Paige Haas Benjamin J Polacco Hannes Braberg Jacqueline M Fabius Manon Eckhardt Margaret Soucheray Melanie J Bennett Merve Cakir Michael J McGregor Qiongyu Li Bjoern Meyer Ferdinand Roesch Thomas Vallet Alice Mac Kain Lisa Miorin Elena Moreno Zun Zar Chi Naing Yuan Zhou Shiming Peng Ying Shi Ziyang Zhang Wenqi Shen Ilsa T Kirby James E Melnyk John S Chorba Kevin Lou Shizhong A Dai Inigo Barrio-Hernandez Danish Memon Claudia Hernandez-Armenta Jiankun Lyu Christopher J P Mathy Tina Perica Kala Bharath Pilla Sai J Ganesan Daniel J Saltzberg Ramachandran Rakesh Xi Liu Sara B Rosenthal Lorenzo Calviello Srivats Venkataramanan Jose Liboy-Lugo Yizhu Lin Xi-Ping Huang YongFeng Liu Stephanie A Wankowicz Markus Bohn Maliheh Safari Fatima S Ugur Cassandra Koh Nastaran Sadat Savar Quang Dinh Tran Djoshkun Shengjuler Sabrina J Fletcher Michael C O'Neal Yiming Cai Jason C J Chang David J Broadhurst Saker Klippsten Phillip P Sharp Nicole A Wenzell Duygu Kuzuoglu-Ozturk Hao-Yuan Wang Raphael Trenker Janet M Young Devin A Cavero Joseph Hiatt Theodore L Roth Ujjwal Rathore Advait Subramanian Julia Noack Mathieu Hubert Robert M Stroud Alan D Frankel Oren S Rosenberg Kliment A Verba David A Agard Melanie Ott Michael Emerman Natalia Jura Mark von Zastrow Eric Verdin Alan Ashworth Olivier Schwartz Christophe d'Enfert Shaeri Mukherjee Matt Jacobson Harmit S Malik Danica G Fujimori Trey Ideker Charles S Craik Stephen N Floor James S Fraser John D Gross Andrej Sali Bryan L Roth Davide Ruggero Jack Taunton Tanja Kortemme Pedro Beltrao Marco Vignuzzi Adolfo García-Sastre Kevan M Shokat Brian K Shoichet Nevan J Krogan

Nature 2020 07 30;583(7816):459-468. Epub 2020 Apr 30.

QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41586-020-2286-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431030PMC
July 2020

Masters Athlete Screening Study (MASS): Insights Into the Psychological Impact of Cardiovascular Preparticipation Screening.

Clin J Sport Med 2020 Feb 13. Epub 2020 Feb 13.

SportsCardiologyBC, UBCH Centre for Cardiovascular Excellence, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/JSM.0000000000000802DOI Listing
February 2020

Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90.

J Am Chem Soc 2020 02 3;142(7):3392-3400. Epub 2020 Feb 3.

Department of Cellular and Molecular Pharmacology , University of California , San Francisco , California 94158 , United States.

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http://dx.doi.org/10.1021/jacs.9b09684DOI Listing
February 2020

Consecutive non-training days over a weekend for assessing cardiac parasympathetic variation in response to accumulated exercise stress.

Eur J Sport Sci 2019 Nov 13:1-11. Epub 2019 Nov 13.

Cardiovascular Physiology & Rehabilitation Laboratory, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1080/17461391.2019.1688397DOI Listing
November 2019

Cartilage recovery in runners with and without knee osteoarthritis: A pilot study.

Knee 2019 Oct 18;26(5):1049-1057. Epub 2019 Aug 18.

Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.knee.2019.07.011DOI Listing
October 2019

Lysine-Targeted Inhibitors and Chemoproteomic Probes.

Annu Rev Biochem 2019 06 11;88:365-381. Epub 2019 Jan 11.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94158, USA; email: ,

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http://dx.doi.org/10.1146/annurev-biochem-061516-044805DOI Listing
June 2019

What are the perceptions about running and knee joint health among the public and healthcare practitioners in Canada?

PLoS One 2018 1;13(10):e0204872. Epub 2018 Oct 1.

Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204872PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166953PMC
March 2019

Efficacy of Hot Yoga as a Heat Stress Technique for Enhancing Plasma Volume and Cardiovascular Performance in Elite Female Field Hockey Players.

J Strength Cond Res 2018 Oct;32(10):2878-2887

Cardiovascular Physiology & Rehabilitation Laboratory, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1519/JSC.0000000000002705DOI Listing
October 2018

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.

Cell Death Dis 2018 03 14;9(3):397. Epub 2018 Mar 14.

Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.

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http://dx.doi.org/10.1038/s41419-018-0427-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852046PMC
March 2018

The effects of different passive static stretching intensities on recovery from unaccustomed eccentric exercise - a randomized controlled trial.

Appl Physiol Nutr Metab 2018 Aug 12;43(8):806-815. Epub 2018 Mar 12.

b Research Centre for Sport Exercise and Performance, Institute of Sport and Human Science, University of Wolverhampton, Walsall WS1 3BD, UK.

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http://dx.doi.org/10.1139/apnm-2017-0841DOI Listing
August 2018

Monitoring the Prescribed and Experienced Heart Rate-Derived Training Loads in Elite Field Hockey Players.

J Strength Cond Res 2019 May;33(5):1394-1399

Cardiovascular Physiology and Rehabilitation Laboratory, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1519/JSC.0000000000002474DOI Listing
May 2019

IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4 and CD8 T cells.

Sci Signal 2017 Dec 19;10(510). Epub 2017 Dec 19.

Rosalind Russell and Ephraim P. Engleman Arthritis Research Center, Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://stke.sciencemag.org/lookup/doi/10.1126/scisignal.aan4
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http://dx.doi.org/10.1126/scisignal.aan4931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741096PMC
December 2017

Mitogen- and stress-activated protein kinase 1 is required for gonadotropin-releasing hormone-mediated activation of gonadotropin α-subunit expression.

J Biol Chem 2017 12 20;292(50):20720-20731. Epub 2017 Oct 20.

From the Faculty of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel and

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http://dx.doi.org/10.1074/jbc.M117.797845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733607PMC
December 2017

Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes.

J Am Chem Soc 2017 01 4;139(2):680-685. Epub 2017 Jan 4.

Medicine Design, Pfizer , Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/jacs.6b08536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858558PMC
January 2017

Regulation of B cell fate by chronic activity of the IgE B cell receptor.

Elife 2016 12 9;5. Epub 2016 Dec 9.

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.

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http://dx.doi.org/10.7554/eLife.21238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207771PMC
December 2016

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.

Cell 2016 11;167(5):1229-1240.e15

MRC-LMB, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119991PMC
November 2016

Detecting Underlying Cardiovascular Disease in Young Competitive Athletes.

Can J Cardiol 2017 01 23;33(1):155-161. Epub 2016 Jun 23.

Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.cjca.2016.06.007DOI Listing
January 2017

Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization.

Mol Cell 2016 08 28;63(3):433-44. Epub 2016 Jul 28.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; The Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122673PMC
August 2016

Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel.

Cell Chem Biol 2016 05;23(5):561-566

Institute of Biotechnology, University of Helsinki, Viikinkaari 1, Biocenter 3, Helsinki 00014, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24519456163012
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http://dx.doi.org/10.1016/j.chembiol.2016.04.008DOI Listing
May 2016

Phase separation of signaling molecules promotes T cell receptor signal transduction.

Science 2016 Apr 7;352(6285):595-9. Epub 2016 Apr 7.

Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA. Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1126/science.aad9964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892427PMC
April 2016

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.

Nat Chem Biol 2016 May 28;12(5):373-9. Epub 2016 Mar 28.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nchembio.2056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837022PMC
May 2016

The Health Benefits of a 12-Week Home-Based Interval Training Cardiac Rehabilitation Program in Patients With Heart Failure.

Can J Cardiol 2016 Apr 4;32(4):561-7. Epub 2016 Feb 4.

Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Physical Activity Promotion and Chronic Disease Prevention Unit, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.01.031DOI Listing
April 2016

A Prospective Pilot Investigation of Brain Volume, White Matter Hyperintensities, and Hemorrhagic Lesions after Mild Traumatic Brain Injury.

Front Neurol 2016 12;7:11. Epub 2016 Feb 12.

UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada; Division of Neurology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.3389/fneur.2016.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751255PMC
February 2016

Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.

Elife 2015 Dec 10;4. Epub 2015 Dec 10.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.

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http://dx.doi.org/10.7554/eLife.10222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786417PMC
December 2015

Allosteric N-WASP activation by an inter-SH3 domain linker in Nck.

Proc Natl Acad Sci U S A 2015 Nov 9;112(47):E6436-45. Epub 2015 Nov 9.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158; The Howard Hughes Medical Institute Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543;

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http://dx.doi.org/10.1073/pnas.1510876112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664294PMC
November 2015

Gait modifications to change lower extremity gait biomechanics in runners: a systematic review.

Br J Sports Med 2015 Nov 23;49(21):1382-8. Epub 2015 Jun 23.

Faculty of Medicine, Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.

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https://www.brasilsaude.org.br/images/documentos/material-ex
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http://dx.doi.org/10.1136/bjsports-2014-094393DOI Listing
November 2015

Targeting protein kinases with selective and semipromiscuous covalent inhibitors.

Methods Enzymol 2014 ;548:93-116

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-397918-6.00004-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265651PMC
July 2015

Covalent docking of large libraries for the discovery of chemical probes.

Nat Chem Biol 2014 Dec 26;10(12):1066-72. Epub 2014 Oct 26.

1] Department of Cellular and Molecular Pharmacology, University of California-San Francisco, San Francisco, California, USA. [2] Howard Hughes Medical Institute, University of California-San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nchembio.1666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232467PMC
December 2014

Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.

J Am Chem Soc 2014 Sep 2;136(36):12624-30. Epub 2014 Sep 2.

Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California-San Francisco , San Francisco, California 94158, United States.

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http://dx.doi.org/10.1021/ja505194wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160273PMC
September 2014

An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate.

Elife 2014 4;3:e01483. Epub 2014 Feb 4.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.

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https://elifesciences.org/articles/01483
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http://dx.doi.org/10.7554/eLife.01483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913039PMC
November 2015

Examining injury risk and pain perception in runners using minimalist footwear.

Br J Sports Med 2014 Aug 19;48(16):1257-62. Epub 2013 Dec 19.

Division of Sports Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://bjsm.bmj.com/lookup/doi/10.1136/bjsports-2012-092061
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http://dx.doi.org/10.1136/bjsports-2012-092061DOI Listing
August 2014

Comparison of a physiotherapy program versus dexamethasone injections for plantar fasciopathy in prolonged standing workers: a randomized clinical trial.

Clin J Sport Med 2014 May;24(3):211-7

*Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, British Columbia, Canada; and †Griffith Health Institute, Griffith University, Southport, Australia.

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http://dx.doi.org/10.1097/JSM.0000000000000021DOI Listing
May 2014

Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei [corrected].

Elife 2013 Jul 9;2:e00712. Epub 2013 Jul 9.

Tetrad Graduate Program , University of California, San Francisco , San Francisco , United States ; Center for Discovery and Innovation in Parasitic Diseases , University of California, San Francisco , San Francisco , United States.

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http://dx.doi.org/10.7554/eLife.00712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707081PMC
July 2013

p90 RSK2 mediates antianoikis signals by both transcription-dependent and -independent mechanisms.

Mol Cell Biol 2013 Jul 22;33(13):2574-85. Epub 2013 Apr 22.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1128/MCB.01677-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700113PMC
July 2013

Electrophilic fragment-based design of reversible covalent kinase inhibitors.

J Am Chem Soc 2013 Apr 29;135(14):5298-301. Epub 2013 Mar 29.

Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1021/ja401221bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665406PMC
April 2013

Proteostasis modulators with discriminating taste.

Chem Biol 2013 Feb;20(2):144-5

Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.chembiol.2013.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647031PMC
February 2013

Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.

Beilstein J Org Chem 2013 4;9:15-25. Epub 2013 Jan 4.

Small Molecule Discovery Center, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA ; Department of Pharmaceutical Chemistry, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA ; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.3762/bjoc.9.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566858PMC
February 2013

Selective targeting of distinct active site nucleophiles by irreversible SRC-family kinase inhibitors.

J Am Chem Soc 2012 Dec 4;134(50):20214-7. Epub 2012 Dec 4.

Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94158, United States.

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http://pubs.acs.org/doi/10.1021/ja310659j
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http://dx.doi.org/10.1021/ja310659jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729023PMC
December 2012

Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation.

Mol Biol Cell 2012 Jul 30;23(14):2712-22. Epub 2012 May 30.

Department of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1091/mbc.E12-03-0228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395660PMC
July 2012

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.

Nat Chem Biol 2012 Apr 1;8(5):471-6. Epub 2012 Apr 1.

Graduate Program in Chemistry and Chemical Biology, University of California-San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nchembio.925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657615PMC
April 2012

Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.

Proc Natl Acad Sci U S A 2012 Apr 7;109(14):5277-82. Epub 2012 Mar 7.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1114487109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325720PMC
April 2012

Functional knee brace use effect on peak vertical ground reaction forces during drop jump landing.

Knee Surg Sports Traumatol Arthrosc 2012 Dec;20(12):2405-12

ACTIN Health and Rehabilitation Inc., 5767 Oak Street, Vancouver, BC, V6M 2V7, Canada.

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http://dx.doi.org/10.1007/s00167-012-1911-zDOI Listing
December 2012

Paralympic medical services for the 2010 paralympic winter games.

Clin J Sport Med 2012 Jan;22(1):10-20

*VANOC Medical Services, Vancouver, British Columbia, Canada †Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, British Columbia, Canada ‡International Paralympic Committee, Medical Committee, Bonn, Germany.

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http://dx.doi.org/10.1097/JSM.0b013e318242ec68DOI Listing
January 2012

The effects of exercise in hypoxic and normoxic conditions on endothelin-1 and arterial compliance.

J Sports Sci 2012 19;30(3):261-7. Epub 2011 Dec 19.

Kinesiology , University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1080/02640414.2011.633546DOI Listing
June 2012

Irreversible Nek2 kinase inhibitors with cellular activity.

J Med Chem 2011 Jun 31;54(12):4133-46. Epub 2011 May 31.

Program in Chemistry and Chemical Biology, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94158, United States.

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http://dx.doi.org/10.1021/jm200222mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663048PMC
June 2011

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

Blood 2011 Jun 28;117(25):6885-94. Epub 2011 Apr 28.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute of Emory, Atlanta, GA, USA.

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http://dx.doi.org/10.1182/blood-2010-10-315721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128480PMC
June 2011

Effect of functional knee brace use on acceleration, agility, leg power and speed performance in healthy athletes.

Br J Sports Med 2011 Dec 18;45(15):1230-7. Epub 2011 Apr 18.

ACTIN Health and Rehabilitation Inc., 5767 Oak Street, Vancouver, BC V6M 2V7, Canada.

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http://dx.doi.org/10.1136/bjsm.2010.079244DOI Listing
December 2011

Ultrasound-guided injections of hyperosmolar dextrose for overuse patellar tendinopathy: a pilot study.

Br J Sports Med 2011 Sep 21;45(12):972-7. Epub 2011 Feb 21.

Department of Orthopedics and Rehabilitation, Universityof Wisconsin, Madison, USA.

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http://dx.doi.org/10.1136/bjsm.2010.081455DOI Listing
September 2011

ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1.

J Biol Chem 2010 Dec 2;285(53):41310-9. Epub 2010 Nov 2.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M110.153775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009856PMC
December 2010

Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia.

J Biol Chem 2010 Nov 3;285(45):35155-68. Epub 2010 Sep 3.

Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1074/jbc.M110.101212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966129PMC
November 2010

The effect of three different levels of footwear stability on pain outcomes in women runners: a randomised control trial.

Br J Sports Med 2011 Jul 27;45(9):715-21. Epub 2010 Jun 27.

Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1136/bjsm.2009.069849DOI Listing
July 2011

p90 activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1.

J Neurochem 2010 Sep 16;114(5):1476-86. Epub 2010 Jun 16.

Department of Neurosurgery, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06868.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924815PMC
September 2010

Favorable outcomes after sonographically guided intratendinous injection of hyperosmolar dextrose for chronic insertional and midportion achilles tendinosis.

AJR Am J Roentgenol 2010 Apr;194(4):1047-53

Experimental Medicine Programme, University of British Columbia, Allan McGavin Sports Medicine Centre, John Owen Pavilion, 3055 Westbrook Mall, Vancouver, BC, Canada V6T 1Z3.

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http://dx.doi.org/10.2214/AJR.09.3255DOI Listing
April 2010

Kinematic analysis of runners with achilles mid-portion tendinopathy.

Foot Ankle Int 2009 Dec;30(12):1190-5

University of British Columbia, Experimental Medicine Program, 602-1355 West 14th, Vancouver V6H1R2, Canada.

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http://journals.sagepub.com/doi/10.3113/FAI.2009.1190
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http://dx.doi.org/10.3113/FAI.2009.1190DOI Listing
December 2009

Target Identification by Diazirine Photo-Cross-linking and Click Chemistry.

Curr Protoc Chem Biol 2009 Dec;1:55-73

Program in Chemistry and Chemical Biology and Department of Cellular and Molecular Pharmacology University of California, San Francisco San Francisco, California 94158-2280, USA.

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http://dx.doi.org/10.1002/9780470559277.ch090167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647699PMC
December 2009

The potential role of prophylactic/functional knee bracing in preventing knee ligament injury.

Sports Med 2009 ;39(11):937-60

School of Physiotherapy, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.2165/11317790-000000000-00000DOI Listing
January 2010

The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function.

J Biol Chem 2009 Aug 1;284(35):23670-81. Epub 2009 Jul 1.

Department of Pharmacology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1074/jbc.M109.032813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749142PMC
August 2009

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis.

Mol Cell 2009 Jan;33(1):109-16

Department of Pathology, NYU Cancer Institute, Smilow Research Center, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655121PMC
January 2009