Jack Favor

Jack Favor

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Jack Favor

Jack Favor

Publications by authors named "Jack Favor"

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Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.

Mol Cancer 2014 Aug 4;13:182. Epub 2014 Aug 4.

Institute of Radiation Biology, Helmholtz-Center Munich, National Research Centre for Health and Environment, Ingolstadter Landstrasse 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1186/1476-4598-13-182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237942PMC
August 2014

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Mamm Genome 2012 Oct 29;23(9-10):611-22. Epub 2012 Aug 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1007/s00335-012-9415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463795PMC
October 2012

COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke.

Am J Hum Genet 2012 Jan 29;90(1):91-101. Epub 2011 Dec 29.

Departments of Ophthalmology and Anatomy, Institute for Human Genetics, University of California, San Francisco School of Medicine, 94143, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292971100500
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http://dx.doi.org/10.1016/j.ajhg.2011.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257894PMC
January 2012

Memorial for Udo H. Ehling (1928-2010).

Environ Mol Mutagen 2011 Apr 6;52(3):171-3. Epub 2011 Jan 6.

Helmholtz Zentrum Muenchen, Ingolstaedter Landstr, Neuherberg, Germany.

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http://dx.doi.org/10.1002/em.20640DOI Listing
April 2011

The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype.

Hum Mol Genet 2011 Jan 13;20(2):223-34. Epub 2010 Oct 13.

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Edinburgh, UK.

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http://dx.doi.org/10.1093/hmg/ddq457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005898PMC
January 2011

Relationship of Pax6 activity levels to the extent of eye development in the mouse, Mus musculus.

Genetics 2008 Jul 18;179(3):1345-55. Epub 2008 Jun 18.

Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1534/genetics.108.088591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475738PMC
July 2008

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

Front Biosci 2008 May 1;13:5810-23. Epub 2008 May 1.

Institute of Developmental Genetics, Helmholtz Center Munich-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

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http://dx.doi.org/10.2741/3118DOI Listing
May 2008

Novel allele of crybb2 in the mouse and its expression in the brain.

Invest Ophthalmol Vis Sci 2008 Apr;49(4):1533-41

Institutes of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.07-0788DOI Listing
April 2008

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse.

Am J Physiol Renal Physiol 2007 Nov 19;293(5):F1736-45. Epub 2007 Sep 19.

Department of Pediatrics, Montreal Children's Hospital, McGill University, Quebec, Canada.

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http://dx.doi.org/10.1152/ajprenal.00221.2007DOI Listing
November 2007

Genetic, biochemical, and molecular characterization of nine glyceraldehyde-3-phosphate dehydrogenase mutants with reduced enzyme activity in Mus musculus.

Mamm Genome 2007 Oct 17;18(10):686-92. Epub 2007 Sep 17.

Institute of Human Genetics, GSF - National Research Center for Environment and Health, Ingolstädter Landstr. 1, D-85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-007-9055-zDOI Listing
October 2007

Endogenous retroviral insertion in Cryge in the mouse No3 cataract mutant.

Genomics 2007 Apr 12;89(4):512-20. Epub 2007 Jan 12.

Section on Molecular Structure and Functional Genomics, National Eye Institute, National Institutes of Health, Building 7, Room 201 Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ygeno.2006.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868556PMC
April 2007

Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina.

Development 2007 Mar 14;134(6):1151-60. Epub 2007 Feb 14.

II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universtität München, Ismaninger Str. 22, D-81675 Munich, Germany.

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http://dx.doi.org/10.1242/dev.02781DOI Listing
March 2007

Variations of eye size parameters among different strains of mice.

Mamm Genome 2006 Aug 4;17(8):851-7. Epub 2006 Aug 4.

Institutes of Developmental Genetics, GSF-National Research Center for Environment and Health, D-85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-006-0019-5DOI Listing
August 2006

Multilocus inheritance determines predisposition to alpha-radiation induced bone tumourigenesis in mice.

Int J Cancer 2006 May;118(9):2132-8

Institute of Pathology, Clinical Cooperation Group Osteosarcoma, GSF National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/ijc.21612DOI Listing
May 2006

Xcat, a novel mouse model for Nance-Horan syndrome inhibits expression of the cytoplasmic-targeted Nhs1 isoform.

Hum Mol Genet 2006 Jan 15;15(2):319-27. Epub 2005 Dec 15.

F.M. Kirby Center for Molecular Ophthalmology, Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, USA.

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http://dx.doi.org/10.1093/hmg/ddi449DOI Listing
January 2006

An ENU-induced mutation in Rs1h causes disruption of retinal structure and function.

Mol Vis 2005 Jul 27;11:569-81. Epub 2005 Jul 27.

Department of Ophthalmology, University of Tennessee Health Science Center and Tennessee Mouse Genome Consortium, Memphis, TN, USA.

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July 2005

Genetic and phenotypic analysis of Tcm, a mutation affecting early eye development.

Mamm Genome 2005 May;16(5):332-43

F.M. Kirby Center for Molecular Ophthalmology, Scheie Eye Institute, University of Pennsylvania School of Medicine, Stellar-Chance Bldg. Rm. 315, 422 Curie Blvd., Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1007/s00335-004-2444-7DOI Listing
May 2005

Transmitted mutational events induced in mouse germ cells following acrylamide or glycidamide exposure.

Mutat Res 2005 Feb;580(1-2):21-30

Institute of Human Genetics, GSF-National Research Center for Environment and Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.mrgentox.2004.09.010DOI Listing
February 2005

Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development.

Development 2004 Dec 17;131(24):6131-40. Epub 2004 Nov 17.

GSF-National Research Center for Environment and Health, Institute for Stem Cell Research, Neuherberg, Germany.

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http://dx.doi.org/10.1242/dev.01524DOI Listing
December 2004

Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification.

Proc Natl Acad Sci U S A 2004 Sep 3;101(37):13566-71. Epub 2004 Sep 3.

Mammalian Genetics Unit and Mary Lyon Centre, Medical Research Council, Harwell, Oxfordshire OX11 0RD, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0405516101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518795PMC
September 2004

Organization and annotation of the Xcat critical region: elimination of seven positional candidate genes.

Genomics 2004 May;83(5):893-901

F.M. Kirby Center for Molecular Ophthalmology, University of Pennsylvania School of Medicine, 422 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ygeno.2003.10.010DOI Listing
May 2004

Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse.

Invest Ophthalmol Vis Sci 2004 Apr;45(4):1202-13

Institute of Developmental Genetics, GSF-National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.03-0811DOI Listing
April 2004

Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin and glucagon content.

Eur J Endocrinol 2004 Mar;150(3):389-95

Diabetes Unit, Department of Medicine, University Hospital Geneva, 24 Micheli-du-Crest, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1530/eje.0.1500389DOI Listing
March 2004

Electroretinography as a screening method for mutations causing retinal dysfunction in mice.

Invest Ophthalmol Vis Sci 2004 Feb;45(2):601-9

GSF-National Research Center for Environment and Health, Institutes of. Developmental Genetics, Clinical Cooperation Group Ophthalmogenetics, Neuherberg, Germany.

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http://dx.doi.org/10.1167/iovs.03-0561DOI Listing
February 2004

Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud.

Development 2003 Dec;130(24):6037-47

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilian University, Munich, Germany.

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http://dx.doi.org/10.1242/dev.00861DOI Listing
December 2003

Crygf(Rop): the first mutation in the Crygf gene causing a unique radial lens opacity.

Invest Ophthalmol Vis Sci 2002 Sep;43(9):2998-3002

National Research Center for Environment and Health (GSF), Institute of Mammalian Genetics, Neuherberg, Germany.

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September 2002

Pax2.1 is required for the development of thyroid follicles in zebrafish.

Development 2002 Aug;129(15):3751-60

Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17, D-50923 Köln, Germany.

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August 2002

Ethylnitrosourea-induced base pair substitution affects splicing of the mouse gammaE-crystallin encoding gene leading to the expression of a hybrid protein and to a cataract.

Genetics 2002 Aug;161(4):1633-40

GSF-National Research Center for Environment and Health, Institute of Mammalian Genetics, D-85764 Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462215PMC
August 2002

Bone tumorigenesis induced by alpha-particle radiation: mapping of genetic loci influencing predisposition in mice.

Radiat Res 2002 Apr;157(4):426-34

Institute of Pathology at the GSF National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1667/0033-7587(2002)157[0426:btibap]2.0.co;2DOI Listing
April 2002

A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.

Invest Ophthalmol Vis Sci 2002 Jan;43(1):236-40

National Research Center for Environment and Health (Forschungszentrum für Umwelt und Gesundheit), Institute of Mammalian Genetics, Neuherberg, Germany.

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January 2002