Publications by authors named "Jack Antel"

100Publications

Multiple Sclerosis as a Syndrome-Implications for Future Management.

Front Neurol 2020 28;11:784. Epub 2020 Aug 28.

Florey Institute of Neuroscience and Mental Health, Florey Department, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fneur.2020.00784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483755PMC
August 2020

Mitochondrial dynamics and bioenergetics regulated by netrin-1 in oligodendrocytes.

Glia 2020 Sep 10. Epub 2020 Sep 10.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/glia.23905DOI Listing
September 2020

Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic.

J Neurol Sci 2020 10 7;417:117085. Epub 2020 Aug 7.

Department of Neurological Surgery, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2020.117085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413162PMC
October 2020

Lesion stage-dependent causes for impaired remyelination in MS.

Acta Neuropathol 2020 09 24;140(3):359-375. Epub 2020 Jul 24.

Institut für Neuropathologie, Universitätsklinikum Münster, Pottkamp 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00401-020-02189-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424408PMC
September 2020

Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells.

J Immunol 2020 Jul 15;205(2):398-406. Epub 2020 Jun 15.

Neuroimmunology Unit, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 0G4, Canada;

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http://dx.doi.org/10.4049/jimmunol.2000129DOI Listing
July 2020

RNA-binding protein altered expression and mislocalization in MS.

Neurol Neuroimmunol Neuroinflamm 2020 05 26;7(3). Epub 2020 Mar 26.

From the Department of Neurology (K.M., Y.S., G.G., R.P.R.) and Department of Pathology (P.P.), University of Chicago Medical Center, IL; Neuroimmunology Research Laboratory (P.L., S.Z., A.P.), Centre du Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), QC, Canada; and Neuroimmunology Unit (F.P., Q.-L.C., J.P.A.), Montreal Neurological Institute, McGill University, QC, Canada.

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http://dx.doi.org/10.1212/NXI.0000000000000704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176246PMC
May 2020

Extensive subpial cortical demyelination is specific to multiple sclerosis.

Brain Pathol 2020 05 3;30(3):641-652. Epub 2020 Feb 3.

Institute of Neuropathology, University Medical Center Göttingen, Georg August University Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1111/bpa.12813DOI Listing
May 2020

Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System.

J Immunol 2020 01;204(2):251-255

Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115; and.

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http://dx.doi.org/10.4049/jimmunol.1900908DOI Listing
January 2020

Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS.

Cell 2019 12 5;179(7):1483-1498.e22. Epub 2019 Dec 5.

Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936326PMC
December 2019

Species differences in immune-mediated CNS tissue injury and repair: A (neuro)inflammatory topic.

Glia 2020 04 14;68(4):811-829. Epub 2019 Nov 14.

Neuroimmunology Unit, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1002/glia.23746DOI Listing
April 2020

Astrocytes in the Pathogenesis of Multiple Sclerosis: An In Situ MicroRNA Study.

J Neuropathol Exp Neurol 2019 12;78(12):1130-1146

Department of Pathology, The Ottawa Hospital, University of Ottawa.

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http://dx.doi.org/10.1093/jnen/nlz098DOI Listing
December 2019

Deep learning for high-throughput quantification of oligodendrocyte ensheathment at single-cell resolution.

Commun Biol 2019 26;2:116. Epub 2019 Mar 26.

McGill Program in Neuroengineering, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, H3A 2B4 Montreal, QC Canada.

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http://dx.doi.org/10.1038/s42003-019-0356-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435748PMC
May 2020

MSJ 2019 - Editorial comment.

Mult Scler 2019 01;25(1):4-5

VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458518819096DOI Listing
January 2019

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation.

Cell 2019 01 17;176(3):581-596.e18. Epub 2019 Jan 17.

Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183162
Publisher Site
http://dx.doi.org/10.1016/j.cell.2018.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440749PMC
January 2019

Helper CD4 T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner.

Glia 2019 04 16;67(4):582-593. Epub 2018 Nov 16.

Department of Exercise Science, Department of Biology, PERFORM Centre, Concordia University, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1002/glia.23503DOI Listing
April 2019

2018 Editors' commentary.

Mult Scler 2018 10;24(11):1394-1395

VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458518801764DOI Listing
October 2018

Therapy in Multiple Sclerosis - Coming of Age.

Authors:
Jack Antel

N Engl J Med 2018 09;379(11):1085-1086

From the Montreal Neurological Institute, McGill University, Montreal.

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http://dx.doi.org/10.1056/NEJMe1810019DOI Listing
September 2018

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

J Neuroinflammation 2018 Apr 19;15(1):114. Epub 2018 Apr 19.

Neuroimmunology Unit, Montreal Neurological Institute, McGill University, 3801 University Street, Room 111, Montréal , QC, H3A 2B3, Canada.

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http://dx.doi.org/10.1186/s12974-018-1136-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907187PMC
April 2018

Immunology of oligodendrocyte precursor cells in vivo and in vitro.

J Neuroimmunol 2019 Jun 13;331:28-35. Epub 2018 Mar 13.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.03.006DOI Listing
June 2019

The reality of "ghosts" in authorship of clinical trials in multiple sclerosis.

Authors:
Jack Antel

Ann Neurol 2018 04;83(4):656-657

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.25199DOI Listing
April 2018

MSJ 2018-editorial comment.

Mult Scler 2018 02;24(2):90-91

VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458518756517DOI Listing
February 2018

MerTK-mediated regulation of myelin phagocytosis by macrophages generated from patients with MS.

Neurol Neuroimmunol Neuroinflamm 2017 Nov 16;4(6):e402. Epub 2017 Oct 16.

Neuroimmunology Unit (L.M.H., J.H.J., S.-Y.W., Y.H.L., H.T., S.A., A.B.-O., J.P.A.), Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; and Multiple Sclerosis Division (A.B.-O.), Department of Neurology and Center for Neuroinflammation and Neurotherapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/NXI.0000000000000402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777663PMC
November 2017

Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2017: Environmental factors, genetics, and epigenetics in MS susceptibility and clinical course.

Mult Scler 2018 01;24(1):4-5

Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1177/1352458517737397DOI Listing
January 2018

Corrigendum: Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Front Cell Neurosci 2017 24;11:256. Epub 2017 Aug 24.

The Royal (Dick) School of Veterinary Studies, University of EdinburghMidlothian, UK.

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http://dx.doi.org/10.3389/fncel.2017.00256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609595PMC
August 2017

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod.

Mult Scler 2017 Aug;23(9):1225-1232

Montreal Neurologic Institute, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1177/1352458517713147DOI Listing
August 2017

Comparative morphology and phagocytic capacity of primary human adult microglia with time-lapse imaging.

J Neuroimmunol 2017 09 22;310:143-149. Epub 2017 May 22.

Department of Exercise Science, Concordia University, Montréal, QC H4B 1R6, Canada; Department of Biology, Concordia University, Canada; PERFORM Centre, Concordia University, Canada; Center for Structural and Functional Genomics, Concordia University, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.05.012DOI Listing
September 2017

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Stem Cell Reports 2017 06;8(6):1727-1742

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK; Oxford Parkinson's Disease Centre, University of Oxford, South Parks Road, Oxford OX1 3QX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470330PMC
June 2017

Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis?

Ann Neurol 2017 Jun 2;81(6):811-824. Epub 2017 Jun 2.

Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.24944DOI Listing
June 2017

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

Neuron 2017 Apr;94(2):278-293.e9

Department of Neurobiology & Behavior, University of California Irvine, Irvine, CA 92697, USA; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482419PMC
April 2017

Dimethyl fumarate-induced lymphopenia in MS due to differential T-cell subset apoptosis.

Neurol Neuroimmunol Neuroinflamm 2017 May 23;4(3):e340. Epub 2017 Mar 23.

Montreal Neurological Institute (M.G., A.R., R.L., P.S.G., J.A., A.B.-O.), McGill University, Montreal, QC, Canada; Brain and Mind Centre (M.G.), University of Sydney, NSW, Australia; Institute of Actuaries of Australia (A.E.); Department of Neurology (F.L., F.Z.), University Medical Center Mainz, Germany; and Department of Neurology (A.R., R.L., A.B.-O.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/NXI.0000000000000340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365096PMC
May 2017

Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.

Front Cell Neurosci 2017 2;11:56. Epub 2017 Mar 2.

The Royal (Dick) School of Veterinary Studies, University of Edinburgh Midlothian, UK.

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http://dx.doi.org/10.3389/fncel.2017.00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332401PMC
March 2017

Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration.

Neuron 2017 Mar;93(5):1082-1093.e5

Department of Neurology and Neurosurgery, Montréal Neurological Institute, McGill University, Montréal, QC H3A 2B4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.02.018DOI Listing
March 2017

Editorial 2017.

Mult Scler 2017 01;23(1)

VU Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/1352458516688643DOI Listing
January 2017

An updated histological classification system for multiple sclerosis lesions.

Acta Neuropathol 2017 01 17;133(1):13-24. Epub 2016 Dec 17.

Center for Brain Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00401-016-1653-yDOI Listing
January 2017

Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.

J Immunol 2017 01 14;198(2):691-698. Epub 2016 Dec 14.

Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada;

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http://dx.doi.org/10.4049/jimmunol.1601649DOI Listing
January 2017

Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis.

Brain Pathol 2017 11 6;27(6):737-747. Epub 2017 Mar 6.

Department of Neuropathology, University Medical Center, Robert-Koch-Straße 40, Göttingen, D-37075, Germany.

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http://dx.doi.org/10.1111/bpa.12450DOI Listing
November 2017

Astrocytes in multiple sclerosis.

Mult Scler 2016 08 19;22(9):1114-24. Epub 2016 Apr 19.

Neuroimmunology, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1177/1352458516643396DOI Listing
August 2016

Differential transcriptional response profiles in human myeloid cell populations.

Clin Immunol 2018 04 16;189:63-74. Epub 2016 Apr 16.

Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.clim.2016.04.006DOI Listing
April 2018

Widening spectrum of inflammatory disorders of the central nervous system.

Authors:
Jack Antel

Curr Opin Neurol 2016 06;29(3):337-9

Neuroimmunology Unit, Montreal Neurologic Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/WCO.0000000000000330DOI Listing
June 2016

Central nervous system inflammation across the age span.

Curr Opin Neurol 2016 06;29(3):381-7

Neuroimmunology Unit, Montreal Neurologic institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/WCO.0000000000000331DOI Listing
June 2016

MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells.

J Immunol 2016 Apr 9;196(8):3375-84. Epub 2016 Mar 9.

Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada;

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http://dx.doi.org/10.4049/jimmunol.1502562DOI Listing
April 2016

Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis.

Ann Clin Transl Neurol 2016 Jan 2;3(1):27-41. Epub 2015 Dec 2.

Neuroimmunology Unit Department of Neurology and Neurosurgery Montreal Neurological Institute and Hospital McGill University Montreal Quebec Canada.

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http://dx.doi.org/10.1002/acn3.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704479PMC
January 2016

CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation.

PLoS One 2016 7;11(1):e0146503. Epub 2016 Jan 7.

Department of Neurology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146503PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704822PMC
July 2016

Editorial 2016.

Mult Scler 2016 Jan;22(1)

Deputy Editor; Europe.

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http://dx.doi.org/10.1177/1352458515622697DOI Listing
January 2016

Production of IL-27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses.

Glia 2016 Apr 9;64(4):553-69. Epub 2015 Dec 9.

Department of Neurosciences, Université De Montréal and CRCHUM Montreal, Quebec, Canada, H2X 0A9.

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http://dx.doi.org/10.1002/glia.22948DOI Listing
April 2016

Sphingosine-1-Phosphate Receptors in the Central Nervous and Immune Systems.

Curr Drug Targets 2016 ;17(16):1841-1850

Jack Antel, Neuroimmunology Unit, Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, Quebec H3A2B4, Canada.

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http://dx.doi.org/10.2174/1389450116666151001112710DOI Listing
August 2017

Sequencing the immunopathologic heterogeneity in multiple sclerosis.

Ann Clin Transl Neurol 2015 Sep;2(9):873-4

Neuroimmunology Unit, Montreal Neurologic Institute, McGill University Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/acn3.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574805PMC
September 2015

Long-term results from a phase 2 extension study of fingolimod at high and approved dose in relapsing multiple sclerosis.

J Neurol 2015 Dec 4;262(12):2627-34. Epub 2015 Sep 4.

Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital, Basel, Switzerland.

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http://dx.doi.org/10.1007/s00415-015-7834-0DOI Listing
December 2015

Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation.

Front Cell Neurosci 2015 4;9:294. Epub 2015 Aug 4.

Department of Obstetrics and Gynaecology, Faculty of Medicine, CHU Ste-Justine Research Centre, Université de Montréal Montréal, QC, Canada ; Department of Neurosciences, Faculty of Medicine, CHU Ste-Justine Research Centre, Université de Montréal Montréal, QC, Canada ; Faculty of Veterinary Medicine, Animal Reproduction Research Centre, Université de Montréal Montréal, QC, Canada.

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http://dx.doi.org/10.3389/fncel.2015.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524165PMC
August 2015

Regulation of human glia by multiple sclerosis disease modifying therapies.

Semin Immunopathol 2015 Nov 11;37(6):639-49. Epub 2015 Aug 11.

Neuroimmunology Unit, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, 3801 University Street, Montreal, QC, H3A 2B4, Canada.

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http://dx.doi.org/10.1007/s00281-015-0514-4DOI Listing
November 2015

Properties of human central nervous system neurons in a glia-depleted (isolated) culture system.

J Neurosci Methods 2015 Sep 18;253:142-50. Epub 2015 Jun 18.

Neuroimmunlogy Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, H3A 2B4, Canada.

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http://dx.doi.org/10.1016/j.jneumeth.2015.06.009DOI Listing
September 2015

Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination.

Acta Neuropathol 2015 Aug 6;130(2):247-61. Epub 2015 May 6.

Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00401-015-1426-zDOI Listing
August 2015

Netrin 1 regulates blood-brain barrier function and neuroinflammation.

Brain 2015 Jun 22;138(Pt 6):1598-612. Epub 2015 Apr 22.

1 Neuroimmunology Unit, Department of Neuroscience, Centre de Recherche du CHUM (CRCHUM), Université de Montréal, Montréal, Québec, Canada

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614143PMC
http://dx.doi.org/10.1093/brain/awv092DOI Listing
June 2015

MSJ-ETC Editorial.

Mult Scler J Exp Transl Clin 2015 Jan-Dec;1:2055217315575457. Epub 2015 Apr 21.

Faculty of Brain Sciences, University College London.

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http://dx.doi.org/10.1177/2055217315575457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408888PMC
April 2015

P2Y12 expression and function in alternatively activated human microglia.

Neurol Neuroimmunol Neuroinflamm 2015 Apr 19;2(2):e80. Epub 2015 Mar 19.

Division of BioMedical Sciences (C.S.M.), Neuroscience, Memorial University of Newfoundland and Labrador, St. John's, Newfoundland, Canada; Neuroimmunology Unit (C.S.M., A.A., A.K., V.T.S.R., M.M.-R., S.Y.L., P.S., A.B.-O., J.P.A.), Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; Center for Neurologic Diseases (O.B.), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and Department of Pathology and Molecular Medicine (S.K.L.), Queens University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1212/NXI.0000000000000080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370387PMC
April 2015

Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain.

J Neurosci 2015 Feb;35(8):3346-59

Neurology and Neurosurgery, Alan Edwards Centre for Research on Pain, and Faculty of Dentistry, McGill University, Montreal Quebec, Canada H3A 0G4, and

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http://dx.doi.org/10.1523/JNEUROSCI.4040-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605560PMC
February 2015

Editor's commentary.

Mult Scler 2015 Jan;21(1):3-4

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http://dx.doi.org/10.1177/1352458515569405DOI Listing
January 2015

Heterogeneity of oligodendrocyte progenitor cells in adult human brain.

Ann Clin Transl Neurol 2014 Apr 26;1(4):272-83. Epub 2014 Mar 26.

Neuroimmunology Unit, Montreal Neurological Institute, McGill University Montreal, Quebec, Canada, H3A 2B4.

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http://dx.doi.org/10.1002/acn3.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292744PMC
April 2014

Direct and indirect effects of immune and central nervous system-resident cells on human oligodendrocyte progenitor cell differentiation.

J Immunol 2015 Jan 10;194(2):761-72. Epub 2014 Dec 10.

Neuroimmunology Unit, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada

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http://dx.doi.org/10.4049/jimmunol.1401156DOI Listing
January 2015

A novel microRNA-132-sirtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis [corrected].

PLoS One 2014 19;9(8):e105421. Epub 2014 Aug 19.

Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; Clinical Research Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; Experimental Therapeutics Program, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105421PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138149PMC
December 2015

Role of p38MAPK in S1P receptor-mediated differentiation of human oligodendrocyte progenitors.

Glia 2014 Aug 9;62(8):1361-75. Epub 2014 May 9.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/glia.22688DOI Listing
August 2014

Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS.

Neurology 2014 Feb 22;82(8):681-90. Epub 2014 Jan 22.

From Neuroscience (E.Z., L.F.-G.), Department of Pathology (D.G.H.), and McGill Centre for Bioinformatics (M.H.), McGill University, Montreal; Neurology (J.A., A.B.-O., Y.L.), Montreal Neurological Hospital, Montreal, Canada; and Neurology (S.B.), UCSF, San Francisco, CA.

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http://dx.doi.org/10.1212/WNL.0000000000000146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945666PMC
February 2014

The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF-1 signaling in rat and human oligodendrocyte progenitors.

Glia 2014 Jan 26;62(1):64-77. Epub 2013 Oct 26.

Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada.

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http://doi.wiley.com/10.1002/glia.22584
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http://dx.doi.org/10.1002/glia.22584DOI Listing
January 2014

Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with multiple sclerosis.

Neurology 2013 Nov 16;81(20):1768-72. Epub 2013 Oct 16.

From the Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Canada.

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http://dx.doi.org/10.1212/01.wnl.0000435564.92609.2cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821716PMC
November 2013

Limited TCF7L2 expression in MS lesions.

PLoS One 2013 20;8(8):e72822. Epub 2013 Aug 20.

Institute of Neuropathology, University Hospital Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072822PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748032PMC
January 2015

Full-length and fragmented netrin-1 in multiple sclerosis plaques are inhibitors of oligodendrocyte precursor cell migration.

Am J Pathol 2013 Sep 4;183(3):673-80. Epub 2013 Jul 4.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2013.06.004DOI Listing
September 2013

miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization.

Ann Neurol 2013 Nov 23;74(5):709-20. Epub 2013 Sep 23.

Neuroimmunology Unit, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec.

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http://dx.doi.org/10.1002/ana.23967DOI Listing
November 2013

Isolating, culturing, and polarizing primary human adult and fetal microglia.

Methods Mol Biol 2013 ;1041:199-211

McGill University, Montreal, Canada.

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http://dx.doi.org/10.1007/978-1-62703-520-0_19DOI Listing
January 2014

Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis.

Am J Pathol 2013 Aug 5;183(2):516-25. Epub 2013 Jun 5.

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2013.04.016DOI Listing
August 2013