Publications by authors named "J S Garcia-Morillo"

32 Publications

Cutaneous and Ganglion Sarcoidosis Induced by Polycaprolactone Facial Filler: A New Expression of ASIA Syndrome?

Eur J Case Rep Intern Med 2021 9;8(7):002652. Epub 2021 Jun 9.

Unidad de Enfermedades Raras y Autoinmunes del Adulto, UGC Medicina Integral, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

Dermal fillers are applied using a minimally invasive technique with a good safety profile. However, they can have side effects. We present the case of a patient who, 2 months after undergoing polycaprolactone (Ellansé) injections, developed nodular facial and nodal lesions that were compatible with sarcoidosis on histology. This complication has not been previously described for polycaprolactone and could be the expression of an autoimmune syndrome induced by adjuvants.

Learning Points: Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a recently devised umbrella term for autoimmune diseases caused by adjuvants.Aesthetic procedures, which are increasingly common, may be a cause of ASIA syndrome.Polycaprolactone is a bioabsorbable polymer with a safe profile but can have adverse events, including systemic sarcoidosis.
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http://dx.doi.org/10.12890/2021_002652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276932PMC
June 2021

Clinical characterization and outcomes of 85 patients with neurosarcoidosis.

Sci Rep 2021 Jul 2;11(1):13735. Epub 2021 Jul 2.

Department of Neurology, Hospital Clínic, Barcelona, Spain.

To analyze the frequency and clinical phenotype of neurosarcoidosis (NS) in one of the largest nationwide cohorts of patients with sarcoidosis reported from southern Europe. NS was evaluated according to the Diagnostic Criteria for Central Nervous System and Peripheral Nervous System Sarcoidosis recently proposed by Stern et al. Pathologic confirmation of granulomatous disease was used to subclassify NS into definite (confirmation in neurological tissue), probable (confirmation in extraneurological tissue) and possible (no histopathological confirmation of the disease). Of the 1532 patients included in the cohort, 85 (5.5%) fulfilled the Stern criteria for NS (49 women, mean age at diagnosis of NS of 47.6 years, 91% White). These patients developed 103 neurological conditions involving the brain (38%), cranial nerves (36%), the meninges (3%), the spinal cord (10%) and the peripheral nerves (14%); no patient had concomitant central and peripheral nerve involvements. In 59 (69%) patients, neurological involvement preceded or was present at the time of diagnosis of the disease. According to the classification proposed by Stern et al., 11 (13%) were classified as a definite NS, 61 (72%) as a probable NS and the remaining 13 (15%) as a possible NS. In comparison with the systemic phenotype of patients without NS, patients with CNS involvement presented a lower frequency of thoracic involvement (82% vs 93%, q = 0.018), a higher frequency of ocular (27% vs 10%, q < 0.001) and salivary gland (15% vs 4%, q = 0.002) WASOG involvements. In contrast, patients with PNS involvement showed a higher frequency of liver involvement (36% vs 12%, p = 0.02) in comparison with patients without NS. Neurosarcoidosis was identified in 5.5% of patients. CNS involvement prevails significantly over PNS involvement, and both conditions do not overlap in any patient. The systemic phenotype associated to each involvement was clearly differentiated, and can be helpful not only in the early identification of neurological involvement, but also in the systemic evaluation of patients diagnosed with neurosarcoidosis.
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http://dx.doi.org/10.1038/s41598-021-92967-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253777PMC
July 2021

[Nail involvement as a solitary manifestation of pemphigus vulgaris at the time of diagnosis].

Medicina (B Aires) 2021 ;81(2):305

Unidad de Enfermedades Autoinmunes y Minoritarias del Adulto, Unidad de Gestión Clínica de Medicina Integral, Hospital Universitario Virgen del Rocío, Sevilla, España. E-mail:

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May 2021

Quality of life and perceived health in patients with porphyrias.

Med Clin (Barc) 2020 Dec 11. Epub 2020 Dec 11.

Servicio de Medicina Interna, Hospital Universitario Virgen del Rocío, Sevilla, España.

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http://dx.doi.org/10.1016/j.medcli.2020.08.014DOI Listing
December 2020

Design and Implementation of a Pressure Monitoring System Based on IoT for Water Supply Networks.

Sensors (Basel) 2020 Jul 30;20(15). Epub 2020 Jul 30.

Department of Agronomy, University of Córdoba, Campus Rabanales, Ed. Da Vinci, 14071 Córdoba, Spain.

Increasing the efficiency of water supply networks is essential in arid and semi-arid regions to ensure the supply of drinking water to the inhabitants. The cost of renovating these systems is high. However, customized management models can facilitate the maintenance and rehabilitation of hydraulic infrastructures by optimizing the use of resources. The implementation of current Internet of Things (IoT) monitoring systems allows decisions to be based on objective data. In water supply systems, IoT helps to monitor the key elements to improve system efficiency. To implement IoT in a water distribution system requires sensors that are suitable for measuring the main hydraulic variables, a communication system that is adaptable to the water service companies and a friendly system for data analysis and visualization. A smart pressure monitoring and alert system was developed using low-cost hardware and open-source software. An Arduino family microcontroller transfers pressure gauge signals using Sigfox communication, a low-power wide-area network (LPWAN). The IoT ThingSpeak platform is used for data analysis and visualization. Additionally, the system can send alarms via SMS/email in real time using the If This, Then That (IFTTT) web service when anomalous pressure data are detected. The pressure monitoring system was successfully implemented in a real water distribution network in Spain. It was able to detect both breakdowns and leaks in real time.
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http://dx.doi.org/10.3390/s20154247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435998PMC
July 2020
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