Iyassu K Sebhat

Iyassu K Sebhat

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Iyassu K Sebhat

Iyassu K Sebhat

Publications by authors named "Iyassu K Sebhat"

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22Publications

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PAN-AMPK Activation Improves Renal Function in a Rat Model of Progressive Diabetic Nephropathy.

J Pharmacol Exp Ther 2019 Oct 12;371(1):45-55. Epub 2019 Jul 12.

Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey

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http://dx.doi.org/10.1124/jpet.119.258244DOI Listing
October 2019

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

ACS Med Chem Lett 2018 Jan 1;9(1):39-44. Epub 2017 Dec 1.

Medicinal Chemistry, PPDM Preclinical ADME, In Vitro Pharmacology, In Vivo Pharmacology, and Biology-Discovery Departments, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767883PMC
January 2018

Small molecule ligands of the human melanocortin-4 receptor.

Curr Top Med Chem 2007 ;7(11):1068-84

Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065-0900, USA.

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http://dx.doi.org/10.2174/156802607780906609DOI Listing
September 2007