Ivana A Souza

Ivana A Souza

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Ivana A Souza

Ivana A Souza

Publications by authors named "Ivana A Souza"

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19Publications

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A neuronal circuit for activating descending modulation of neuropathic pain.

Nat Neurosci 2019 Oct 9;22(10):1659-1668. Epub 2019 Sep 9.

Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1038/s41593-019-0481-5DOI Listing
October 2019

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels.

Mol Brain 2019 Sep 2;12(1):75. Epub 2019 Sep 2.

Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.

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http://dx.doi.org/10.1186/s13041-019-0494-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720858PMC
September 2019

Interactions of Rabconnectin-3 with Cav2 calcium channels.

Mol Brain 2019 Jun 28;12(1):62. Epub 2019 Jun 28.

Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr. NW, Calgary, T2N 4N1, Canada.

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http://dx.doi.org/10.1186/s13041-019-0483-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599304PMC
June 2019

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Authors:
Katherine L Helbig Robert J Lauerer Jacqueline C Bahr Ivana A Souza Candace T Myers Betül Uysal Niklas Schwarz Maria A Gandini Sun Huang Boris Keren Cyril Mignot Alexandra Afenjar Thierry Billette de Villemeur Delphine Héron Caroline Nava Stéphanie Valence Julien Buratti Christina R Fagerberg Kristina P Soerensen Maria Kibaek Erik-Jan Kamsteeg David A Koolen Boudewijn Gunning H Jurgen Schelhaas Michael C Kruer Jordana Fox Somayeh Bakhtiari Randa Jarrar Sergio Padilla-Lopez Kristin Lindstrom Sheng Chih Jin Xue Zeng Kaya Bilguvar Antigone Papavasileiou Qinghe Xing Changlian Zhu Katja Boysen Filippo Vairo Brendan C Lanpher Eric W Klee Jan-Mendelt Tillema Eric T Payne Margot A Cousin Teresa M Kruisselbrink Myra J Wick Joshua Baker Eric Haan Nicholas Smith Azita Sadeghpour Erica E Davis Nicholas Katsanis Mark A Corbett Alastair H MacLennan Jozef Gecz Saskia Biskup Eva Goldmann Lance H Rodan Elizabeth Kichula Eric Segal Kelly E Jackson Alexander Asamoah David Dimmock Julie McCarrier Lorenzo D Botto Francis Filloux Tatiana Tvrdik Gregory D Cascino Sherry Klingerman Catherine Neumann Raymond Wang Jessie C Jacobsen Melinda A Nolan Russell G Snell Klaus Lehnert Lynette G Sadleir Britt-Marie Anderlid Malin Kvarnung Renzo Guerrini Michael J Friez Michael J Lyons Jennifer Leonhard Gabriel Kringlen Kari Casas Christelle M El Achkar Lacey A Smith Alexander Rotenberg Annapurna Poduri Alba Sanchis-Juan Keren J Carss Julia Rankin Adam Zeman F Lucy Raymond Moira Blyth Bronwyn Kerr Karla Ruiz Jill Urquhart Imelda Hughes Siddharth Banka Ulrike B S Hedrich Ingrid E Scheffer Ingo Helbig Gerald W Zamponi Holger Lerche Heather C Mefford

Am J Hum Genet 2019 Mar;104(3):562

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http://dx.doi.org/10.1016/j.ajhg.2019.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407522PMC
March 2019

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC.

Mol Brain 2019 02 8;12(1):12. Epub 2019 Feb 8.

Molecular Neuroscience, Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr. NW, Calgary, T2N 4N1, Canada.

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https://molecularbrain.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s13041-019-0433-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368719PMC
February 2019

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Authors:
Katherine L Helbig Robert J Lauerer Jacqueline C Bahr Ivana A Souza Candace T Myers Betül Uysal Niklas Schwarz Maria A Gandini Sun Huang Boris Keren Cyril Mignot Alexandra Afenjar Thierry Billette de Villemeur Delphine Héron Caroline Nava Stéphanie Valence Julien Buratti Christina R Fagerberg Kristina P Soerensen Maria Kibaek Erik-Jan Kamsteeg David A Koolen Boudewijn Gunning H Jurgen Schelhaas Michael C Kruer Jordana Fox Somayeh Bakhtiari Randa Jarrar Sergio Padilla-Lopez Kristin Lindstrom Sheng Chih Jin Xue Zeng Kaya Bilguvar Antigone Papavasileiou Qinghe Xing Changlian Zhu Katja Boysen Filippo Vairo Brendan C Lanpher Eric W Klee Jan-Mendelt Tillema Eric T Payne Margot A Cousin Teresa M Kruisselbrink Myra J Wick Joshua Baker Eric Haan Nicholas Smith Azita Sadeghpour Erica E Davis Nicholas Katsanis Mark A Corbett Alastair H MacLennan Jozef Gecz Saskia Biskup Eva Goldmann Lance H Rodan Elizabeth Kichula Eric Segal Kelly E Jackson Alexander Asamoah David Dimmock Julie McCarrier Lorenzo D Botto Francis Filloux Tatiana Tvrdik Gregory D Cascino Sherry Klingerman Catherine Neumann Raymond Wang Jessie C Jacobsen Melinda A Nolan Russell G Snell Klaus Lehnert Lynette G Sadleir Britt-Marie Anderlid Malin Kvarnung Renzo Guerrini Michael J Friez Michael J Lyons Jennifer Leonhard Gabriel Kringlen Kari Casas Christelle M El Achkar Lacey A Smith Alexander Rotenberg Annapurna Poduri Alba Sanchis-Juan Keren J Carss Julia Rankin Adam Zeman F Lucy Raymond Moira Blyth Bronwyn Kerr Karla Ruiz Jill Urquhart Imelda Hughes Siddharth Banka Ulrike B S Hedrich Ingrid E Scheffer Ingo Helbig Gerald W Zamponi Holger Lerche Heather C Mefford

Am J Hum Genet 2018 11 18;103(5):666-678. Epub 2018 Oct 18.

Division of Genetic Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183031
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http://dx.doi.org/10.1016/j.ajhg.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216110PMC
November 2018

Identification of interleukin-1 beta as a key mediator in the upregulation of Cav3.2-USP5 interactions in the pain pathway.

Mol Pain 2017 Jan-Dec;13:1744806917724698

1Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Canada.

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http://journals.sagepub.com/doi/10.1177/1744806917724698
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http://dx.doi.org/10.1177/1744806917724698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560507PMC
September 2018

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

Mol Brain 2018 05 2;11(1):24. Epub 2018 May 2.

Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr. NW, Calgary, T2N 4N1, Canada.

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http://dx.doi.org/10.1186/s13041-018-0368-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930937PMC
May 2018

BK Potassium Channels Suppress Cavα2δ Subunit Function to Reduce Inflammatory and Neuropathic Pain.

Cell Rep 2018 02;22(8):1956-1964

Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.073DOI Listing
February 2018

Down-regulation of T-type Cav3.2 channels by hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1): Evidence of a signaling complex.

Channels (Austin) 2017 Sep 3;11(5):434-443. Epub 2017 May 3.

a Department of Physiology and Pharmacology , Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary , Calgary , Alberta , Canada.

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http://dx.doi.org/10.1080/19336950.2017.1326233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626362PMC
September 2017

Two heterozygous Cav3.2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects.

Pflugers Arch 2016 Apr 26;468(4):635-42. Epub 2015 Dec 26.

Department of Physiology and Pharmacology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr. NW, Calgary, T2N 4N1, Canada.

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http://dx.doi.org/10.1007/s00424-015-1776-3DOI Listing
April 2016

Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice.

Front Cell Neurosci 2016 24;10:74. Epub 2016 Mar 24.

Department of Physiology and Pharmacology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary Calgary, AB, Canada.

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http://dx.doi.org/10.3389/fncel.2016.00074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805597PMC
April 2016

Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain.

Cell Rep 2015 Aug 23;12(5):752-9. Epub 2015 Jul 23.

Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada; Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.07.001DOI Listing
August 2015

The Cav1.2 N terminus contains a CaM kinase site that modulates channel trafficking and function.

Pflugers Arch 2015 Apr 28;467(4):677-86. Epub 2014 May 28.

Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.

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http://dx.doi.org/10.1007/s00424-014-1538-7DOI Listing
April 2015

The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity.

Neuron 2014 Sep;83(5):1144-58

Department of Physiology and Pharmacology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.07.036DOI Listing
September 2014

Block of T-type calcium channels by protoxins I and II.

Mol Brain 2014 May 9;7:36. Epub 2014 May 9.

Department of Physiology & Pharmacology, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive, Calgary, NW, Canada.

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http://dx.doi.org/10.1186/1756-6606-7-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030284PMC
May 2014

Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.

PLoS Biol 2011 Nov 8;9(11):e1001194. Epub 2011 Nov 8.

Molecular Brain Research Group, Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pbio.1001194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210783PMC
November 2011